Molecular insights into the inhibition of glutamate dehydrogenase by the dicarboxylic acid metabolites.
Allosteric Regulation
Amino Acid Sequence
Aspergillus
/ enzymology
Aspergillus niger
Catalytic Domain
Coenzymes
/ metabolism
Dicarboxylic Acids
/ metabolism
Enzyme Inhibitors
/ chemistry
Glutamate Dehydrogenase
/ antagonists & inhibitors
Glutamate Dehydrogenase (NADP+)
/ metabolism
Ketoglutaric Acids
/ metabolism
Kinetics
Metabolome
NADP
/ metabolism
Protein Binding
Aspergillus terreus
crystal structure
dicarboxylic acid metabolites
glutamate dehydrogenase
malonate
succinate
tartrate
Journal
Proteins
ISSN: 1097-0134
Titre abrégé: Proteins
Pays: United States
ID NLM: 8700181
Informations de publication
Date de publication:
03 2022
03 2022
Historique:
revised:
02
11
2021
received:
10
08
2021
accepted:
03
11
2021
pubmed:
9
11
2021
medline:
17
3
2022
entrez:
8
11
2021
Statut:
ppublish
Résumé
Glutamate dehydrogenase (GDH) is a salient metabolic enzyme which catalyzes the NAD
Substances chimiques
Coenzymes
0
Dicarboxylic Acids
0
Enzyme Inhibitors
0
Ketoglutaric Acids
0
NADP
53-59-8
Glutamate Dehydrogenase
EC 1.4.1.2
Glutamate Dehydrogenase (NADP+)
EC 1.4.1.4
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
810-823Informations de copyright
© 2021 Wiley Periodicals LLC.
Références
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