Reference-grade Taxus genome unleashes its pharmacological potential.

Paclitaxel Phylogeny Taxus / genetics
Taxus WGD genome paclitaxel taxadiene synthase

Journal

Trends in plant science
ISSN: 1878-4372
Titre abrégé: Trends Plant Sci
Pays: England
ID NLM: 9890299

Informations de publication

Date de publication:
01 2022
Historique:
received: 21 09 2021
revised: 24 10 2021
accepted: 26 10 2021
pubmed: 14 11 2021
medline: 28 1 2022
entrez: 13 11 2021
Statut: ppublish

Résumé

The genus Taxus is well known for its anticancer metabolite, paclitaxel. Recent releases of chromosome-scale reference genomes for two Taxus species (Xiong et al. and Cheng et al.) now provide novel insights on genome structure and phylogenomics and the origin and evolution of the paclitaxel biosynthesis pathway.

Identifiants

DOI: 10.1016/j.tplants.2021.10.010 PMID: 34772612
pubmed: 34772612
pii: S1360-1385(21)00302-2
doi: 10.1016/j.tplants.2021.10.010
pii:
doi:

Substances chimiques

Paclitaxel P88XT4IS4D

Types de publication

Journal Article Comment

Langues

eng

Sous-ensembles de citation

IM

Pagination

10-12

Commentaires et corrections

Type : CommentOn
Type : CommentOn

Informations de copyright

Copyright © 2021 Elsevier Ltd. All rights reserved.

Auteurs

Ling Kui (L)

Shenzhen Qianhai Shekou Free Trade Zone Hospital, Shenzhen 518067, China; School of Pharmacy, Jiangsu University, Zhenjiang 212013, China; Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA.

Aasim Majeed (A)

School of Agricultural Biotechnology, Punjab Agriculture University, Ludhiana 141004, India.

Yang Dong (Y)

BGI Institute of Applied Agriculture, BGI-Shenzhen, Shenzhen 518120, China; State Key Laboratory for Conservation and Utilization of Bio-Resources in Yunnan, Kunming 650201, China. Electronic address: loyalyang@163.com.

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Classifications MeSH

questionsmedicales.fr › Composés chimiques organiques › Hydrocarbures › Terpènes › Diterpènes › Taxoïdes › Paclitaxel › Reference-grade Taxus genome unleashes its...
questionsmedicales.fr › Sciences de l'information › Phylogenèse › Reference-grade Taxus genome unleashes its...
questionsmedicales.fr › Eucaryotes › Viridiplantae › Streptophyta › Embryophyta › Tracheobionta › Pinales › Taxaceae › Taxus › Reference-grade Taxus genome unleashes its...