The genome of the diatom Chaetoceros tenuissimus carries an ancient integrated fragment of an extant virus.
Journal
Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288
Informations de publication
Date de publication:
24 11 2021
24 11 2021
Historique:
received:
21
04
2021
accepted:
11
10
2021
entrez:
25
11
2021
pubmed:
26
11
2021
medline:
3
2
2022
Statut:
epublish
Résumé
Diatoms are one of the most prominent oceanic primary producers and are now recognized to be distributed throughout the world. They maintain their population despite predators, infections, and unfavourable environmental conditions. One of the smallest diatoms, Chaetoceros tenuissimus, can coexist with infectious viruses during blooms. To further understand this relationship, we sequenced the C. tenuissimus strain NIES-3715 genome. A gene fragment of a replication-associated gene from the infectious ssDNA virus (designated endogenous virus-like fragment, EVLF) was found to be integrated into each 41 Mb of haploid assembly. In addition, the EVLF was transcriptionally active and conserved in nine other C. tenuissimus strains from different geographical areas, although the primary structures of their proteins varied. The phylogenetic tree further suggested that the EVLF was acquired by the ancestor of C. tenuissimus. Additionally, retrotransposon genes possessing a reverse transcriptase function were more abundant in C. tenuissimus than in Thalassiosira pseudonana and Phaeodactylum tricornutum. Moreover, a target site duplication, a hallmark for long interspersed nuclear element retrotransposons, flanked the EVLF. Therefore, the EVLF was likely integrated by a retrotransposon during viral infection. The present study provides further insights into the diatom-virus evolutionary relationship.
Identifiants
pubmed: 34819553
doi: 10.1038/s41598-021-00565-3
pii: 10.1038/s41598-021-00565-3
pmc: PMC8613185
doi:
Substances chimiques
DNA, Single-Stranded
0
Retroelements
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
22877Subventions
Organisme : Japan Society for the Promotion of Science
ID : Young Scientists (A) (22688016)
Informations de copyright
© 2021. The Author(s).
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