Healthy myeloid-derived suppressor cells express the surface ectoenzyme Vanin-2 (VNN2).

Amidohydrolases / metabolism Biomarkers / analysis CD8-Positive T-Lymphocytes / immunology Cell Adhesion Molecules / metabolism Cell Proliferation / physiology GPI-Linked Proteins / metabolism Glioma / diagnosis HLA-DR Antigens / metabolism Humans Lipopolysaccharide Receptors / metabolism Lymphocyte Activation / immunology Membrane Proteins / metabolism Monocytes / immunology Myeloid-Derived Suppressor Cells / immunology Neoplasm Grading Protein Array Analysis Sialic Acid Binding Ig-like Lectin 3 / metabolism
GPI-80 Immunosuppression Mo-MDSC VNN2

Journal

Molecular immunology
ISSN: 1872-9142
Titre abrégé: Mol Immunol
Pays: England
ID NLM: 7905289

Informations de publication

Date de publication:
02 2022
Historique:
received: 21 06 2021
revised: 18 11 2021
accepted: 09 12 2021
pubmed: 26 12 2021
medline: 24 2 2022
entrez: 25 12 2021
Statut: ppublish

Résumé

Study of human monocytic Myeloid-Derived Suppressor cells Mo-MDSC (CD14

Identifiants

DOI: 10.1016/j.molimm.2021.12.011 PMID: 34953280 PMC: PMC8800381
pubmed: 34953280
pii: S0161-5890(21)00350-3
doi: 10.1016/j.molimm.2021.12.011
pmc: PMC8800381
mid: NIHMS1766753
pii:
doi:

Substances chimiques

Biomarkers 0
CD14 protein, human 0
CD33 protein, human 0
Cell Adhesion Molecules 0
GPI-Linked Proteins 0
HLA-DR Antigens 0
Lipopolysaccharide Receptors 0
Membrane Proteins 0
Sialic Acid Binding Ig-like Lectin 3 0
Amidohydrolases EC 3.5.-
VNN2 protein, human EC 3.5.1.92

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1-10

Subventions

Organisme : NIAMS NIH HHS
ID : P30 AR039750
Pays : United States
Organisme : NIAMS NIH HHS
ID : P50 AR055508
Pays : United States
Organisme : NIAMS NIH HHS
ID : R01 AR051498
Pays : United States
Organisme : NCI NIH HHS
ID : R21 CA256573
Pays : United States

Informations de copyright

Copyright © 2021 Elsevier Ltd. All rights reserved.

Références

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Auteurs

David C Soler (DC)

The Department of Neurosurgery, USA; The Brain Tumor and Neuro-Oncology Center, and the Center of Excellence for Translational Neuro-Oncology, USA; University Hospitals-Seidman Center and the Case Comprehensive Cancer Center, USA.

Amber Kerstetter-Fogle (A)

The Department of Neurosurgery, USA; The Brain Tumor and Neuro-Oncology Center, and the Center of Excellence for Translational Neuro-Oncology, USA; University Hospitals-Seidman Center and the Case Comprehensive Cancer Center, USA.

Andrew B Young (AB)

The Department of Dermatology, University Hospitals-Cleveland Medical Center and the Case Western University School of Medicine, 11100 Euclid Avenue, Cleveland, OH, 44106, USA; The Murdough Family Center for Psoriasis, University Hospitals-Cleveland Medical Center and the Case Western University School of Medicine, 11100 Euclid Avenue, Cleveland, OH, 44106, USA.

Pat Rayman (P)

Case Western Reserve University School of Medicine, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, OH, 44195, USA.

James H Finke (JH)

Case Western Reserve University School of Medicine, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, OH, 44195, USA.

Sarah M Debanne (SM)

Epidemiology and Biostatistics, USA.

Kevin D Cooper (KD)

The Department of Dermatology, University Hospitals-Cleveland Medical Center and the Case Western University School of Medicine, 11100 Euclid Avenue, Cleveland, OH, 44106, USA; The Murdough Family Center for Psoriasis, University Hospitals-Cleveland Medical Center and the Case Western University School of Medicine, 11100 Euclid Avenue, Cleveland, OH, 44106, USA.

Jill Barnholtz-Sloan (J)

The Department of Neurosurgery, USA; The Brain Tumor and Neuro-Oncology Center, and the Center of Excellence for Translational Neuro-Oncology, USA; University Hospitals-Seidman Center and the Case Comprehensive Cancer Center, USA; Epidemiology and Biostatistics, USA.

Andrew E Sloan (AE)

The Department of Neurosurgery, USA; The Brain Tumor and Neuro-Oncology Center, and the Center of Excellence for Translational Neuro-Oncology, USA; University Hospitals-Seidman Center and the Case Comprehensive Cancer Center, USA.

Thomas S McCormick (TS)

The Department of Dermatology, University Hospitals-Cleveland Medical Center and the Case Western University School of Medicine, 11100 Euclid Avenue, Cleveland, OH, 44106, USA; The Murdough Family Center for Psoriasis, University Hospitals-Cleveland Medical Center and the Case Western University School of Medicine, 11100 Euclid Avenue, Cleveland, OH, 44106, USA. Electronic address: tsm4@case.edu.

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Classifications MeSH

questionsmedicales.fr › Enzymes et coenzymes › Enzymes › Hydrolases › Amidohydrolases › Healthy myeloid-derived suppressor cells...
questionsmedicales.fr › Facteurs biologiques › Marqueurs biologiques › Healthy myeloid-derived suppressor cells...
questionsmedicales.fr › Systèmes sanguin et immunitaire › Système immunitaire › Leucocytes › Agranulocytes › Lymphocytes › Lymphocytes T › Lymphocytes T CD8+ › Healthy myeloid-derived suppressor cells...
questionsmedicales.fr › Facteurs biologiques › Antigènes › Antigènes de surface › Molécules d'adhérence cellulaire › Healthy myeloid-derived suppressor cells...
questionsmedicales.fr › Phénomènes physiologiques › Croissance et développement › Croissance › Processus de croissance cellulaire › Prolifération cellulaire › Healthy myeloid-derived suppressor cells...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Glycoprotéines membranaires › Protéines liées au GPI › Healthy myeloid-derived suppressor cells...
questionsmedicales.fr › Tumeurs › Tumeurs par type histologique › Tumeurs du tissu nerveux › Tumeurs neuroectodermiques › Tumeurs neuroépitheliales › Gliome › Healthy myeloid-derived suppressor cells...
questionsmedicales.fr › Facteurs biologiques › Antigènes › Isoantigènes › Antigènes d'histocompatibilité › Antigènes HLA › Antigènes HLA-D › Antigènes HLA-DR › Healthy myeloid-derived suppressor cells...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Healthy myeloid-derived suppressor cells...
questionsmedicales.fr › Facteurs biologiques › Marqueurs biologiques › Antigènes de différenciation › Antigènes de différenciation des myélomonocytes › Antigènes CD14 › Healthy myeloid-derived suppressor cells...
questionsmedicales.fr › Phénomènes du système immunitaire › Activation des lymphocytes › Healthy myeloid-derived suppressor cells...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Healthy myeloid-derived suppressor cells...
questionsmedicales.fr › Systèmes sanguin et immunitaire › Système immunitaire › Phagocytes › Monocytes › Healthy myeloid-derived suppressor cells...
questionsmedicales.fr › Cellules › Cellules myéloïdes › Cellules myéloïdes suppressives › Healthy myeloid-derived suppressor cells...
questionsmedicales.fr › Diagnostic › Pronostic › Grading des tumeurs › Healthy myeloid-derived suppressor cells...
questionsmedicales.fr › Techniques d'investigation › Techniques de sonde moléculaire › Analyse par réseau de protéines › Healthy myeloid-derived suppressor cells...
questionsmedicales.fr › Facteurs biologiques › Marqueurs biologiques › Antigènes de différenciation › Antigènes de différenciation des myélomonocytes › Lectine-3 de type Ig liant l'acide sialique › Healthy myeloid-derived suppressor cells...