Characterization of the Morphological Nature of Hollow Spray Dried Dispersion Particles Using X-ray Submicron-Computed Tomography.

materials science morphology physical characterization solid dispersion spray drying

Journal

AAPS PharmSciTech
ISSN: 1530-9932
Titre abrégé: AAPS PharmSciTech
Pays: United States
ID NLM: 100960111

Informations de publication

Date de publication:
28 Dec 2021
Historique:
received: 13 09 2021
accepted: 18 11 2021
entrez: 29 12 2021
pubmed: 30 12 2021
medline: 31 12 2021
Statut: epublish

Résumé

Graphical Abstract.

Identifiants

pubmed: 34964066
doi: 10.1208/s12249-021-02184-7
pii: 10.1208/s12249-021-02184-7
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

40

Informations de copyright

© 2021. The Author(s), under exclusive licence to American Association of Pharmaceutical Scientists.

Références

Tobyn M, Brown J, Dennis AB, Fakes M, Gao Q, Gamble J, et al. Amorphous drug-PVP dispersions: application of theoretical, thermal and spectroscopic analytical techniques to the study of a molecule with intermolecular bonds in both the crystalline and pure amorphous state. J Pharm Sci. 2009;98(9):3456–68.
doi: 10.1002/jps.21738
Paudel A, Worku ZA, Meeus J, Guns S, Van Den Mooter G. Manufacturing of solid dispersions of poorly water soluble drugs by spray drying: formulation and process considerations. Int J Pharm. 2013;453(1):253–84.
doi: 10.1016/j.ijpharm.2012.07.015
Wegiel LA, Mauer LJ, Edgar KJ, Taylor LS. Crystallization of amorphous solid dispersions of resveratrol during preparation and storage-impact of different polymers. J Pharm Sci. 2013;102(1):171–84.
doi: 10.1002/jps.23358
Al-Khattawi A, Bayly A, Phillips A, Wilson D. The design and scale-up of spray dried particle delivery systems. Expert Opin Drug Deliv. 2018;15(1):47–63.
doi: 10.1080/17425247.2017.1321634
Elversson J, Millqvist-Fureby A, Alderborn G, Elofsson U. Droplet and particle size relationship and shell thickness of inhalable lactose particles during spray drying. J Pharm Sci. 2003;92(4):900–10.
doi: 10.1002/jps.10352
Gamble JF, Terada M, Holzner C, Lavery L, Nicholson SJ, Timmins P, Tobyn M. Application of X-ray microtomography for the characterisation of hollow polymer-stabilised spray dried amorphous dispersion particles. Int J Pharm. 2016;510(1):1–8.
doi: 10.1016/j.ijpharm.2016.05.051
Gamble JF, Ferreira AP, Tobyn M, DiMemmo L, Martin K, Mathias N, Schild R, Vig B, Baumann JM, Parks S, Ashton M. Application of imaging based tools for the characterisation of hollow spray dried amorphous dispersion particles. Int J Pharm. 2014;465(1-2):210–7.
doi: 10.1016/j.ijpharm.2014.02.002
Vehring R, Foss WR, Lechuga-Ballesteros D. Particle formation in spray drying. J Aerosol Sci. 2007;38(7):728–46.
doi: 10.1016/j.jaerosci.2007.04.005
Vehring R. Pharmaceutical particle engineering via spray drying. Pharm Res. 2008;25(5):999–1022.
doi: 10.1007/s11095-007-9475-1
Maher PG, Auty MAE, Roos YH, Zychowski LM, Fenelon MA. Microstructure and lactose crystallization properties in spray dried nanoemulsions. Food Struct. 2015;3(0):1–11.
doi: 10.1016/j.foostr.2014.10.001
Zhang S, Stroud PA, Zhu A, Johnson MJ, Lomeo J, Burcham CL, Hinds J, Allen-Francis Blakely K, Walworth MJ. Characterizing the impact of spray dried particle morphology on tablet dissolution using quantitative X-ray microscopy. Eur J Pharm Sci. 2021;165:105921.
doi: 10.1016/j.ejps.2021.105921
Elversson J, Millqvist-Fureby A. Particle size and density in spray drying—effects of carbohydrate properties. J Pharm Sci. 2005;94(9):2049–60.
doi: 10.1002/jps.20418
Hsieh DS, Yue H, Nicholson SJ, Roberts D, Schild R, Gamble JF, Lindrud M. The secondary drying and the fate of organic solvents for spray dried dispersion drug product. Pharm Res. 2015;32(5):1804–16.
doi: 10.1007/s11095-014-1577-y
Vicente J, Pinto J, Menezes J, Gaspar F. Fundamental analysis of particle formation in spray drying. Powder Technol. 2013;247:1–7.
doi: 10.1016/j.powtec.2013.06.038
Bosquillon C, Rouxhet PG, Ahimou F, Simon D, Culot C, Préat V, Vanbever R. Aerosolization properties, surface composition and physical state of spray-dried protein powders. J Control Release. 2004;99(3):357–67.
doi: 10.1016/j.jconrel.2004.07.022
Yates I, Regan D, Ketner R, Gamble JF, editors. Calculation of wall thickness and solid volume fraction of spray dried particles by mercury intrusion. AAPS; 2015; Orlando, USA.
Wong J, D’Sa D, Foley M, Chan J, Chan H-K. NanoXCT: A novel technique to probe the internal architecture of pharmaceutical particles. Pharm Res. 2014;31(11):3085–94.
doi: 10.1007/s11095-014-1401-8
De Chiffre L, Carmignato S, Kruth JP, Schmitt R, Weckenmann A. Industrial applications of computed tomography. CIRP Ann. 2014;63(2):655–77.
doi: 10.1016/j.cirp.2014.05.011
Kampschulte M, Langheinirch A, Sender J, Litzlbauer H, Althöhn U, Schwab J, Alejandre-Lafont E, Martels G, Krombach G. Nano-computed tomography: technique and applications. RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren. 2016;188(02):146–54.
doi: 10.1055/s-0041-106541
Zabler S, Ullherr M, Fella C, Schielein R, Focke O, Zeller-Plumhoff B, Lhuissier P, DeBoever W, Hanke R. Comparing image quality in phase contrast subμ X-raytomography—A round-robin study. Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment 2020;951:162992.
Paganin D, Mayo SC, Gureyev TE, Miller PR, Wilkins SW. Simultaneous phase and amplitude extraction from a single defocused image of a homogeneous object. J Microsc. 2002;206(1):33–40.
doi: 10.1046/j.1365-2818.2002.01010.x
Xi H, Zhu A, Klinzing GR, Zhou L, Zhang S, Gmitter AJ, Ploeger K, Sundararajan P, Mahjour M, Xu W. Characterization of spray dried particles through microstructural imaging. J Pharm Sci. 2020;109(11):3404–12.
doi: 10.1016/j.xphs.2020.07.032
Zhang S, Zhu A. Reconstruction of thin wall features marginally resolved by multi-dimensional images. Application No. 17/204,726. Filing Date 17 March 2021.
Zhang S, Byrnes AP, Jankovic J, Neilly J. Management, analysis, and simulation of micrographs with cloud computing. Microscopy Today. 2019;27(2):26–33.
doi: 10.1017/S1551929519000026

Auteurs

John F Gamble (JF)

Materials Science & Engineering, Bristol Myers Squibb, Reeds Lane, Moreton, Wirral, CH46 1QW, UK. john.gamble@bms.com.

Mike Tobyn (M)

Materials Science & Engineering, Bristol Myers Squibb, Reeds Lane, Moreton, Wirral, CH46 1QW, UK.

Shawn Zhang (S)

DigiM Solution LLC, Burlington, Massachusetts, 01803, USA.

Aiden Zhu (A)

DigiM Solution LLC, Burlington, Massachusetts, 01803, USA.

Jakub Šalplachta (J)

CEITEC - Central European Institute of Technology, Brno University of Technology, Purkynova 656/123, 612 00, Brno, Czech Republic.

Jan Matula (J)

CEITEC - Central European Institute of Technology, Brno University of Technology, Purkynova 656/123, 612 00, Brno, Czech Republic.

Tomáš Zikmund (T)

CEITEC - Central European Institute of Technology, Brno University of Technology, Purkynova 656/123, 612 00, Brno, Czech Republic.

Jozef Kaiser (J)

CEITEC - Central European Institute of Technology, Brno University of Technology, Purkynova 656/123, 612 00, Brno, Czech Republic.

Peter Oberta (P)

Institute of Physics, Academy of Sciences of the Czech Republic v.v.i., Na Slovance 1999/2, 182 21, Praha 8, Czech Republic.

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Classifications MeSH