Control of Variant Surface Glycoprotein Expression by CFB2 in Trypanosoma brucei and Quantitative Proteomic Connections to Translation and Cytokinesis.


Journal

mSphere
ISSN: 2379-5042
Titre abrégé: mSphere
Pays: United States
ID NLM: 101674533

Informations de publication

Date de publication:
27 04 2022
Historique:
pubmed: 22 3 2022
medline: 30 4 2022
entrez: 21 3 2022
Statut: ppublish

Résumé

Variant surface glycoproteins (VSGs) coat parasitic African trypanosomes and underpin antigenic variation and immune evasion. These VSGs are superabundant virulence factors that are subject to posttranscriptional gene expression controls mediated via the

Identifiants

pubmed: 35306877
doi: 10.1128/msphere.00069-22
pmc: PMC9044945
doi:

Substances chimiques

3' Untranslated Regions 0
Membrane Glycoproteins 0
RNA, Messenger 0
Ribosomal Proteins 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

e0006922

Subventions

Organisme : Wellcome Trust
ID : 217105/Z/19/Z
Pays : United Kingdom
Organisme : Wellcome Trust
ID : 101842/Z13/Z
Pays : United Kingdom
Organisme : Wellcome Trust
ID : 097945/B/11/Z
Pays : United Kingdom

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Auteurs

Gustavo Bravo Ruiz (G)

The Wellcome Trust Centre for Anti-Infectives Research, School of Life Sciences, University of Dundeegrid.8241.f, Dundee, United Kingdom.

Michele Tinti (M)

The Wellcome Trust Centre for Anti-Infectives Research, School of Life Sciences, University of Dundeegrid.8241.f, Dundee, United Kingdom.

Melanie Ridgway (M)

The Wellcome Trust Centre for Anti-Infectives Research, School of Life Sciences, University of Dundeegrid.8241.f, Dundee, United Kingdom.

David Horn (D)

The Wellcome Trust Centre for Anti-Infectives Research, School of Life Sciences, University of Dundeegrid.8241.f, Dundee, United Kingdom.

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Classifications MeSH