One-step ultra-sensitive immunochromatographic strip authenticating an emergent fraud acetophenetidin in herbal tea.
Acetophenetidin
Antibody
Hapten
Herbal tea
Immunochromatography
Strip
Journal
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
ISSN: 1873-6351
Titre abrégé: Food Chem Toxicol
Pays: England
ID NLM: 8207483
Informations de publication
Date de publication:
Jul 2022
Jul 2022
Historique:
received:
10
03
2022
revised:
17
05
2022
accepted:
23
05
2022
pubmed:
2
6
2022
medline:
18
6
2022
entrez:
1
6
2022
Statut:
ppublish
Résumé
Herbal tea is a highly popular and widely consumed beverage. However, a pain-relieving and fever-reducing drug, acetophenetidin, was recently found to illegally occur in herbal tea for a fraud purpose. Due to the potential health risk and urgent requirement for on-site screening method, a one-step and high specificity strip for identifying acetophenetidin was developed for the first time. Assisted by computational chemistry, four haptens were designed to prepare immunogens and coating antigens for antibody generation, and a specific antibody with ultra-sensitivity and high specificity was generated, showing half maximal inhibitory (IC
Identifiants
pubmed: 35643229
pii: S0278-6915(22)00381-7
doi: 10.1016/j.fct.2022.113183
pii:
doi:
Substances chimiques
Antibodies
0
Teas, Herbal
0
Gold
7440-57-5
Phenacetin
ER0CTH01H9
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
113183Informations de copyright
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