Paracetamol Treatment for Patent Ductus Arteriosus, an Apparent Association with Acute Hemolysis in Three Preterm Infants: Case Series.
Case series
Hemolysis
Paracetamol
Patent ductus arteriosus
Preterm infants
Journal
Neonatology
ISSN: 1661-7819
Titre abrégé: Neonatology
Pays: Switzerland
ID NLM: 101286577
Informations de publication
Date de publication:
2022
2022
Historique:
received:
14
03
2022
accepted:
11
05
2022
pubmed:
22
6
2022
medline:
22
7
2022
entrez:
21
6
2022
Statut:
ppublish
Résumé
We report three preterm infants who were treated with paracetamol for hemodynamically significant patent ductus arteriosus and developed acute hemolysis. No other apparent cause of acute hemolysis was found during Neonatal Intensive Care Unit hospitalization. All three infants were born within 1 year. As this side effect of paracetamol has not been reported previously and many preterm infants receive paracetamol for PDA closure, we advocate awareness. We cannot be sure whether the hemolysis occurred due to an underlying cause that was augmented by paracetamol or whether the drug itself caused acute hemolysis in these preterm infants.
Identifiants
pubmed: 35728580
pii: 000525128
doi: 10.1159/000525128
doi:
Substances chimiques
Acetaminophen
362O9ITL9D
Ibuprofen
WK2XYI10QM
Types de publication
Case Reports
Langues
eng
Sous-ensembles de citation
IM
Pagination
530-534Informations de copyright
© 2022 The Author(s). Published by S. Karger AG, Basel.