Single-nucleus profiling of human dilated and hypertrophic cardiomyopathy.
CRISPR-Cas Systems
Cardiomyopathy, Dilated
/ genetics
Cardiomyopathy, Hypertrophic
/ genetics
Case-Control Studies
Cell Nucleus
/ genetics
Cells, Cultured
Gene Expression Profiling
Gene Knockout Techniques
Heart Failure
/ genetics
Heart Ventricles
/ metabolism
Humans
Myocardium
/ metabolism
Myofibroblasts
/ metabolism
RNA-Seq
Single-Cell Analysis
Transcription, Genetic
Transforming Growth Factor beta1
Journal
Nature
ISSN: 1476-4687
Titre abrégé: Nature
Pays: England
ID NLM: 0410462
Informations de publication
Date de publication:
08 2022
08 2022
Historique:
received:
24
02
2021
accepted:
27
04
2022
pubmed:
23
6
2022
medline:
9
8
2022
entrez:
22
6
2022
Statut:
ppublish
Résumé
Heart failure encompasses a heterogeneous set of clinical features that converge on impaired cardiac contractile function
Identifiants
pubmed: 35732739
doi: 10.1038/s41586-022-04817-8
pii: 10.1038/s41586-022-04817-8
doi:
Substances chimiques
Transforming Growth Factor beta1
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
174-180Subventions
Organisme : NHLBI NIH HHS
ID : R01 HL128914
Pays : United States
Organisme : NHLBI NIH HHS
ID : K24 HL105780
Pays : United States
Organisme : NIH HHS
ID : S10 OD026839
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL105993
Pays : United States
Organisme : NHLBI NIH HHS
ID : K01 HL140187
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL092577
Pays : United States
Organisme : American Heart Association-American Stroke Association
Pays : United States
Informations de copyright
© 2022. The Author(s), under exclusive licence to Springer Nature Limited.
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