Nicking mechanism underlying the DNA phosphorothioate-sensing antiphage defense by SspE.

DNA, Bacterial / genetics Genome, Bacterial DNA / genetics Phosphates / metabolism Guanosine Triphosphate

Journal

Nature communications
ISSN: 2041-1723
Titre abrégé: Nat Commun
Pays: England
ID NLM: 101528555

Informations de publication

Date de publication:
09 11 2022
Historique:
received: 14 08 2022
accepted: 26 10 2022
entrez: 9 11 2022
pubmed: 10 11 2022
medline: 15 11 2022
Statut: epublish

Résumé

DNA phosphorothioate (PT) modification, with a nonbridging phosphate oxygen substituted by sulfur, represents a widespread epigenetic marker in prokaryotes and provides protection against genetic parasites. In the PT-based defense system Ssp, SspABCD confers a single-stranded PT modification of host DNA in the 5'-C

Identifiants

DOI: 10.1038/s41467-022-34505-0 PMID: 36351933 PMC: PMC9646914
pubmed: 36351933
doi: 10.1038/s41467-022-34505-0
pii: 10.1038/s41467-022-34505-0
pmc: PMC9646914
doi:

Substances chimiques

DNA, Bacterial 0
DNA 9007-49-2
thiophosphoric acid TYM4M7EWCW
Phosphates 0
Guanosine Triphosphate 86-01-1

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

6773

Informations de copyright

© 2022. The Author(s).

Références

Chem Biol. 1996 May;3(5):319-23
pubmed: 8807859
Nucleic Acids Res. 2021 Apr 19;49(7):3672-3680
pubmed: 33764453
Int J Biol Macromol. 2020 Dec 1;164:4415-4422
pubmed: 32926904
FEMS Microbiol Rev. 2019 Mar 1;43(2):109-122
pubmed: 30289455
Biochemistry. 2007 Jun 19;46(24):7215-25
pubmed: 17516660
Nucleic Acids Res. 2016 Jan 8;44(1):485-95
pubmed: 26635397
Nat Commun. 2019 Apr 11;10(1):1688
pubmed: 30975999
Nucleic Acid Ther. 2014 Dec;24(6):374-87
pubmed: 25353652
Nucleic Acids Res. 2021 Nov 8;49(19):11257-11273
pubmed: 34657954
J Appl Crystallogr. 2007 Aug 1;40(Pt 4):658-674
pubmed: 19461840
PLoS Genet. 2010 Dec 23;6(12):e1001253
pubmed: 21203499
Nat Commun. 2022 Aug 2;13(1):4491
pubmed: 35918338
Mol Microbiol. 2014 Aug;93(4):776-85
pubmed: 25040300
Acta Crystallogr D Biol Crystallogr. 1994 Sep 1;50(Pt 5):760-3
pubmed: 15299374
Structure. 2004 Feb;12(2):205-14
pubmed: 14962381
Nat Chem Biol. 2007 Nov;3(11):709-10
pubmed: 17934475
Bioinformatics. 2013 Apr 1;29(7):845-54
pubmed: 23407358
Acta Crystallogr D Biol Crystallogr. 1997 May 1;53(Pt 3):240-55
pubmed: 15299926
Proc Natl Acad Sci U S A. 2011 Feb 15;108(7):2963-8
pubmed: 21285367
Nucleic Acids Res. 2010 Nov;38(20):7133-41
pubmed: 20627870
Proc Natl Acad Sci U S A. 2020 Jun 23;117(25):14322-14330
pubmed: 32518115
Nat Commun. 2018 Nov 8;9(1):4689
pubmed: 30409991
Assay Drug Dev Technol. 2011 Aug;9(4):342-53
pubmed: 21812660
Proteins. 2010 Nov 15;78(15):3150-5
pubmed: 20806233
Nucleic Acids Res. 2005 Jul 1;33(Web Server issue):W299-302
pubmed: 15980475
Methods Enzymol. 1997;276:307-26
pubmed: 27754618
Nat Commun. 2014 Jun 05;5:3951
pubmed: 24899568
Proc Natl Acad Sci U S A. 2017 Apr 25;114(17):4501-4506
pubmed: 28400512
Sci Rep. 2014 Oct 16;4:6642
pubmed: 25319634
Proc Natl Acad Sci U S A. 2018 Mar 27;115(13):E2988-E2996
pubmed: 29531068
Protein Sci. 2006 Feb;15(2):269-80
pubmed: 16434744
Nucleic Acids Res. 2004 Jul 1;32(Web Server issue):W610-4
pubmed: 15215461
Biophys J. 2004 Aug;87(2):899-906
pubmed: 15298897
Cell. 2014 Feb 27;156(5):935-49
pubmed: 24529477
Acta Crystallogr D Biol Crystallogr. 2010 Apr;66(Pt 4):486-501
pubmed: 20383002
Nat Microbiol. 2020 Jul;5(7):917-928
pubmed: 32251370
Acta Crystallogr D Biol Crystallogr. 2004 Dec;60(Pt 12 Pt 1):2126-32
pubmed: 15572765

Auteurs

Haiyan Gao (H)

Department of Gastroenterology, TaiKang Center for Life and Medical Sciences, Zhongnan Hospital of Wuhan University, School of Pharmaceutical Sciences, Wuhan University, Wuhan, 430071, China.
State Key Laboratory of Microbial Metabolism, School of Life Sciences & Biotechnology, The Joint International Research Laboratory of Metabolic & Developmental Sciences, Shanghai Jiao Tong University, Shanghai, 200240, China.
ORCID: 0000-0001-6158-7552

Xinqi Gong (X)

Mathematics Intelligence Application Lab, Institute for Mathematical Sciences, Renmin University of China, Beijing, 100872, China.
ORCID: 0000-0003-2802-6176

Jinchuan Zhou (J)

Department of Gastroenterology, TaiKang Center for Life and Medical Sciences, Zhongnan Hospital of Wuhan University, School of Pharmaceutical Sciences, Wuhan University, Wuhan, 430071, China.

Yubing Zhang (Y)

Department of Gastroenterology, TaiKang Center for Life and Medical Sciences, Zhongnan Hospital of Wuhan University, School of Pharmaceutical Sciences, Wuhan University, Wuhan, 430071, China.
State Key Laboratory of Microbial Metabolism, School of Life Sciences & Biotechnology, The Joint International Research Laboratory of Metabolic & Developmental Sciences, Shanghai Jiao Tong University, Shanghai, 200240, China.

Jinsong Duan (J)

State Key Laboratory of Membrane Biology, Beijing Advanced Innovation Center for Structural Biology, School of Life Sciences, Tsinghua University, Beijing, 100084, China.

Yue Wei (Y)

Department of Gastroenterology, TaiKang Center for Life and Medical Sciences, Zhongnan Hospital of Wuhan University, School of Pharmaceutical Sciences, Wuhan University, Wuhan, 430071, China.
Department of Burn and Plastic Surgery, Shenzhen Institute of Translational Medicine, Health Science Center, the First Affiliated Hospital of Shenzhen University, Shenzhen Second People's Hospital, Shenzhen, 518035, China.

Liuqing Chen (L)

State Key Laboratory of Microbial Metabolism, School of Life Sciences & Biotechnology, The Joint International Research Laboratory of Metabolic & Developmental Sciences, Shanghai Jiao Tong University, Shanghai, 200240, China.

Zixin Deng (Z)

Department of Gastroenterology, TaiKang Center for Life and Medical Sciences, Zhongnan Hospital of Wuhan University, School of Pharmaceutical Sciences, Wuhan University, Wuhan, 430071, China.
ORCID: 0000-0003-0724-3390

Jiawei Wang (J)

State Key Laboratory of Membrane Biology, Beijing Advanced Innovation Center for Structural Biology, School of Life Sciences, Tsinghua University, Beijing, 100084, China.
ORCID: 0000-0001-9893-8539

Shi Chen (S)

Department of Gastroenterology, TaiKang Center for Life and Medical Sciences, Zhongnan Hospital of Wuhan University, School of Pharmaceutical Sciences, Wuhan University, Wuhan, 430071, China. shichen@whu.edu.cn.
Department of Burn and Plastic Surgery, Shenzhen Institute of Translational Medicine, Health Science Center, the First Affiliated Hospital of Shenzhen University, Shenzhen Second People's Hospital, Shenzhen, 518035, China. shichen@whu.edu.cn.
ORCID: 0000-0002-8965-1015

Geng Wu (G)

State Key Laboratory of Microbial Metabolism, School of Life Sciences & Biotechnology, The Joint International Research Laboratory of Metabolic & Developmental Sciences, Shanghai Jiao Tong University, Shanghai, 200240, China. geng.wu@sjtu.edu.cn.
ORCID: 0000-0002-1120-8638

Lianrong Wang (L)

Department of Gastroenterology, TaiKang Center for Life and Medical Sciences, Zhongnan Hospital of Wuhan University, School of Pharmaceutical Sciences, Wuhan University, Wuhan, 430071, China. lianrong@whu.edu.cn.
ORCID: 0000-0003-1669-6340

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Classifications MeSH

questionsmedicales.fr › Acides nucléiques, nucléotides et nucléosides › Acides nucléiques › ADN › ADN bactérien › Nicking mechanism underlying the DNA...
questionsmedicales.fr › Phénomènes génétiques › Structures génétiques › Génome › Génome microbien › Génome bactérien › Nicking mechanism underlying the DNA...
questionsmedicales.fr › Acides nucléiques, nucléotides et nucléosides › Acides nucléiques › ADN › Nicking mechanism underlying the DNA...
questionsmedicales.fr › Produits chimiques inorganiques › Composés du phosphore › Acides du phosphore › Acides phosphoriques › Phosphates › Nicking mechanism underlying the DNA...
questionsmedicales.fr › Acides nucléiques, nucléotides et nucléosides › Nucléotides › Ribonucléotides › Nucléotides guanyliques › Guanosine triphosphate › Nicking mechanism underlying the DNA...