Unravelling the complexity of enzyme catalysis.
catalysis
drug discovery
enzyme kinetics
enzymes
phosphorylation
thermodynamics
Journal
The FEBS journal
ISSN: 1742-4658
Titre abrégé: FEBS J
Pays: England
ID NLM: 101229646
Informations de publication
Date de publication:
05 2023
05 2023
Historique:
received:
03
04
2023
accepted:
11
04
2023
medline:
4
5
2023
pubmed:
3
5
2023
entrez:
3
5
2023
Statut:
ppublish
Résumé
The study of enzymes never disappoints. Despite its long history-almost 150 years following the first documented use of the word enzyme in 1878-the field of enzymology advances apace. This long journey has witnessed landmark developments that have defined modern enzymology as a broad discipline, leading to improved understanding at the molecular level, as we aspire to discover the complex relationships between enzyme structures, catalytic mechanisms and biological function. How enzymes are regulated at the gene and post-translational levels and how catalytic activity is modulated by interactions with small ligands and macromolecules, or the broader enzyme environment, are topical areas of study. Insights from such studies guide the exploitation of natural and engineered enzymes in biomedical or industrial processes; for example, in diagnostics, pharmaceuticals manufacture and processing technologies that use immobilised enzymes and enzyme reactor-based systems. In this Focus Issue, The FEBS Journal seeks to highlight breaking science and informative reviews, as well as personal reflections, to illustrate the breadth and importance of contemporary molecular enzymology research.
Substances chimiques
Enzymes
0
Types de publication
Editorial
Langues
eng
Sous-ensembles de citation
IM
Pagination
2204-2207Informations de copyright
© 2023 Federation of European Biochemical Societies.
Références
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