Predicting the Three-Dimensional Structure of the c-

G-Quadruplexes Promoter Regions, Genetic / genetics DNA / chemistry Proto-Oncogenes

Journal

The journal of physical chemistry letters
ISSN: 1948-7185
Titre abrégé: J Phys Chem Lett
Pays: United States
ID NLM: 101526034

Informations de publication

Date de publication:
25 May 2023
Historique:
medline: 26 5 2023
pubmed: 12 5 2023
entrez: 12 5 2023
Statut: ppublish

Résumé

Guanine quadruplexes (G4s) play essential protective and regulatory roles within cells, influencing gene expression. In several gene-promoter regions, multiple G4-forming sequences are in close proximity and may form three-dimensional arrangements. We analyze the interplay among the three neighboring G4s in the c-

Identifiants

DOI: 10.1021/acs.jpclett.3c00765 PMID: 37171167
pubmed: 37171167
doi: 10.1021/acs.jpclett.3c00765
doi:

Substances chimiques

DNA 9007-49-2

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

4704-4710

Auteurs

Emmanuelle Bignon (E)

Université de Lorraine and CNRS, UMR 7019 LPCT, F-54000 Nancy, France.
ORCID: 0000-0001-9475-5049

Angelo Spinello (A)

Department of Biological, Chemical and Pharmaceutical Sciences and Technologies Viale delle Scienze, Università di Palermo, Edificio 17, 90128 Palermo, Italy.
ORCID: 0000-0002-8387-8956

Tom Miclot (T)

Université de Lorraine and CNRS, UMR 7019 LPCT, F-54000 Nancy, France.
Department of Biological, Chemical and Pharmaceutical Sciences and Technologies Viale delle Scienze, Università di Palermo, Edificio 17, 90128 Palermo, Italy.

Luisa D'Anna (L)

Department of Biological, Chemical and Pharmaceutical Sciences and Technologies Viale delle Scienze, Università di Palermo, Edificio 17, 90128 Palermo, Italy.
ORCID: 0000-0002-7046-5140

Cosimo Ducani (C)

Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm 171 65, Sweden.
Moligo Technologies AB, Banvaktsvägen 20, 171 48 Solna, Sweden.
ORCID: 0000-0002-5877-1049

Stéphanie Grandemange (S)

Université de Lorraine and CNRS, UMR 7039 CRAN, F-54000 Nancy, France.

Giampaolo Barone (G)

Department of Biological, Chemical and Pharmaceutical Sciences and Technologies Viale delle Scienze, Università di Palermo, Edificio 17, 90128 Palermo, Italy.
ORCID: 0000-0001-8773-2359

Antonio Monari (A)

Université Paris Cité and CNRS, ITODYS, F-75006 Paris, France.
ORCID: 0000-0001-9464-1463

Alessio Terenzi (A)

Department of Biological, Chemical and Pharmaceutical Sciences and Technologies Viale delle Scienze, Università di Palermo, Edificio 17, 90128 Palermo, Italy.
ORCID: 0000-0001-9751-1373

Articles similaires

A computational model for bacteriophage ϕX174 gene expression.

Alexis M Hill, Tanvi A Ingle, Claus O Wilke
1.00
Gene Expression Regulation, Viral Promoter Regions, Genetic Bacteriophage phi X 174 Computer Simulation Models, Genetic

iDNA-ITLM: An interpretable and transferable learning model for identifying DNA methylation.

Xia Yu, Cui Yani, Zhichao Wang et al.
1.00
DNA Methylation Humans DNA Animals Machine Learning

Structural basis for human OGG1 processing 8-oxodGuo within nucleosome core particles.

Mengtian Ren, Fabian Gut, Yilan Fan et al.
1.00
DNA Glycosylases Nucleosomes Humans 8-Hydroxy-2'-Deoxyguanosine DNA Repair

Genome-wide analysis of the Amorphophallus konjac AkCSLA gene family and its functional characterization in drought tolerance of transgenic arabidopsis.

Changxin Luo, Shicheng Luo, Zhe Chen et al.
1.00
Arabidopsis Amorphophallus Plants, Genetically Modified Phylogeny Droughts

Classifications MeSH

questionsmedicales.fr › Phénomènes génétiques › Structures génétiques › Conformation d'acide nucléique › G-quadruplexes › Predicting the Three-Dimensional Structure of the c-
questionsmedicales.fr › Phénomènes génétiques › Structures génétiques › Génome › Composants de génome › Gènes › Composants de gène › Éléments de régulation transcriptionnelle › Régions promotrices (génétique) › Predicting the Three-Dimensional Structure of the c-
questionsmedicales.fr › Acides nucléiques, nucléotides et nucléosides › Acides nucléiques › ADN › Predicting the Three-Dimensional Structure of the c-
questionsmedicales.fr › Phénomènes génétiques › Structures génétiques › Génome › Composants de génome › Gènes › Gènes tumoraux › Oncogènes › Proto-oncogènes › Predicting the Three-Dimensional Structure of the c-