Engineering the biological conversion of formate into crotonate in Cupriavidus necator.
C1 bioeconomy
Crotonate
Cupriavidus necator
Fed-batch
Formate
Formate toxicity
Modular pathway engineering
Reverse beta-oxidation
Journal
Metabolic engineering
ISSN: 1096-7184
Titre abrégé: Metab Eng
Pays: Belgium
ID NLM: 9815657
Informations de publication
Date de publication:
09 2023
09 2023
Historique:
received:
14
03
2023
revised:
08
06
2023
accepted:
29
06
2023
medline:
12
9
2023
pubmed:
7
7
2023
entrez:
6
7
2023
Statut:
ppublish
Résumé
To advance the sustainability of the biobased economy, our society needs to develop novel bioprocesses based on truly renewable resources. The C1-molecule formate is increasingly proposed as carbon and energy source for microbial fermentations, as it can be efficiently generated electrochemically from CO
Identifiants
pubmed: 37414134
pii: S1096-7176(23)00097-6
doi: 10.1016/j.ymben.2023.06.015
pii:
doi:
Substances chimiques
formic acid
0YIW783RG1
Crotonates
0
Formates
0
Carbon
7440-44-0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
49-65Informations de copyright
Copyright © 2023 The Authors. Published by Elsevier Inc. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of competing interest F.C., A.K. and F.K. are employed by b.fab GmbH, a German biotech company aiming for the biomanufacturing of proteins and chemicals from C1 feedstocks. The other authors declare no competing interest.