FAN1 removes triplet repeat extrusions via a PCNA- and RFC-dependent mechanism.


Journal

Proceedings of the National Academy of Sciences of the United States of America
ISSN: 1091-6490
Titre abrégé: Proc Natl Acad Sci U S A
Pays: United States
ID NLM: 7505876

Informations de publication

Date de publication:
15 08 2023
Historique:
medline: 9 8 2023
pubmed: 7 8 2023
entrez: 7 8 2023
Statut: ppublish

Résumé

Human genome-wide association studies have identified

Identifiants

pubmed: 37549289
doi: 10.1073/pnas.2302103120
pmc: PMC10438374
doi:

Substances chimiques

Cell Extracts 0
Endodeoxyribonucleases EC 3.1.-
Endonucleases EC 3.1.-
Exodeoxyribonucleases EC 3.1.-
FAN1 protein, human EC 3.1.-
Multifunctional Enzymes 0
Proliferating Cell Nuclear Antigen 0

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

e2302103120

Subventions

Organisme : NINDS NIH HHS
ID : R01 NS118082
Pays : United States
Organisme : NINDS NIH HHS
ID : R03 NS114976
Pays : United States
Organisme : NCI NIH HHS
ID : P30 CA056036
Pays : United States

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Auteurs

Ashutosh S Phadte (AS)

Department of Biochemistry and Molecular Biology, Thomas Jefferson University, Philadelphia, PA 19107.

Mayuri Bhatia (M)

Department of Biochemistry and Molecular Biology, Thomas Jefferson University, Philadelphia, PA 19107.

Hope Ebert (H)

Department of Biochemistry and Molecular Biology, Thomas Jefferson University, Philadelphia, PA 19107.

Haaris Abdullah (H)

Department of Biochemistry and Molecular Biology, Thomas Jefferson University, Philadelphia, PA 19107.

Essam Abed Elrazaq (EA)

Department of Biochemistry and Molecular Biology, Thomas Jefferson University, Philadelphia, PA 19107.

Konstantin E Komolov (KE)

Department of Biochemistry and Molecular Biology, Thomas Jefferson University, Philadelphia, PA 19107.

Anna Pluciennik (A)

Department of Biochemistry and Molecular Biology, Thomas Jefferson University, Philadelphia, PA 19107.

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Classifications MeSH