A molecular analysis of substituted phenylethylamines as potential microtubule targeting agents through in silico methods and in vitro microtubule-polymerization activity.


Journal

Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288

Informations de publication

Date de publication:
01 09 2023
Historique:
received: 19 06 2023
accepted: 29 08 2023
medline: 4 9 2023
pubmed: 2 9 2023
entrez: 1 9 2023
Statut: epublish

Résumé

Natural phenethylamines are trace amine neurotransmitters associated with dopamine transmission and related illnesses such Parkinson's disease, and addiction. Synthetic phenethylamines can have psychoactive and hallucinogenic effects due to their high affinity with the 5-HT

Identifiants

pubmed: 37658096
doi: 10.1038/s41598-023-41600-9
pii: 10.1038/s41598-023-41600-9
pmc: PMC10474033
doi:

Substances chimiques

Phenethylamines 0
Colchicine SML2Y3J35T

Types de publication

Journal Article Research Support, U.S. Gov't, Non-P.H.S. Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

14406

Informations de copyright

© 2023. Springer Nature Limited.

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Auteurs

Isadora Rocha De Abreu (IR)

Clinical Systems Biology Group, Institute for Neuro-Immune Medicine, Nova Southeastern University, Fort Lauderdale, FL, USA.
Department of Psychology and Neuroscience, Nova Southeastern University, Fort Lauderdale, FL, USA.

Allison Barkdull (A)

Clinical Systems Biology Group, Institute for Neuro-Immune Medicine, Nova Southeastern University, Fort Lauderdale, FL, USA.
Department of Biomedical Engineering, University of Florida, Gainesville, FL, USA.

James R Munoz (JR)

Department of Psychology and Neuroscience, Nova Southeastern University, Fort Lauderdale, FL, USA.

Robert P Smith (RP)

Cell Therapy Institute, Dr. Kiran C. Patel College of Osteopathic Medicine, Nova Southeastern University, Fort Lauderdale, FL, USA.

Travis J A Craddock (TJA)

Clinical Systems Biology Group, Institute for Neuro-Immune Medicine, Nova Southeastern University, Fort Lauderdale, FL, USA. tcraddock@nova.edu.
Department of Psychology and Neuroscience, Nova Southeastern University, Fort Lauderdale, FL, USA. tcraddock@nova.edu.
Departments of Computer Science, and Clinical Immunology, Nova Southeastern University, Fort Lauderdale, FL, USA. tcraddock@nova.edu.

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Classifications MeSH