Free-Energy Landscape and Rate Estimation of the Aromatic Ring Flips in Basic Pancreatic Trypsin Inhibitors Using Metadynamics.


Journal

Journal of chemical theory and computation
ISSN: 1549-9626
Titre abrégé: J Chem Theory Comput
Pays: United States
ID NLM: 101232704

Informations de publication

Date de publication:
10 Oct 2023
Historique:
medline: 11 10 2023
pubmed: 12 9 2023
entrez: 12 9 2023
Statut: ppublish

Résumé

Aromatic side chains (phenylalanine and tyrosine) of a protein flip by 180° around the

Identifiants

pubmed: 37698852
doi: 10.1021/acs.jctc.3c00460
pmc: PMC10569046
doi:

Substances chimiques

Aprotinin 9087-70-1
Trypsin Inhibitors 0
Tyrosine 42HK56048U
Phenylalanine 47E5O17Y3R

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

6605-6618

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Auteurs

Mandar Kulkarni (M)

Division of Biophysical Chemistry, Lund University, Chemical Center, 22100 Lund, Sweden.

Pär Söderhjelm (P)

Division of Biophysical Chemistry, Lund University, Chemical Center, 22100 Lund, Sweden.

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Classifications MeSH