Ultrasonic-assisted supercritical fluid separation removing plasticizers from ganoderma lucidum spores' oil.

Ganoderma lucidum spores’ oil Nanofiltration Plasticizer Triterpenes Ultrasonic-assisted supercritical fluid separation

Journal

Ultrasonics sonochemistry
ISSN: 1873-2828
Titre abrégé: Ultrason Sonochem
Pays: Netherlands
ID NLM: 9433356

Informations de publication

Date de publication:
Nov 2023
Historique:
received: 14 07 2023
revised: 04 09 2023
accepted: 22 09 2023
medline: 6 11 2023
pubmed: 28 9 2023
entrez: 27 9 2023
Statut: ppublish

Résumé

Ultrasonic-assisted supercritical fluid separation (USFS) was firstly applied to regulate solubility and remove plasticizers from ganoderma lucidum spores' oil to improve product safety. Separation efficiency was related with four variables, including temperature, pressure and ultrasonic power. The QD-T6A ultrasonic generator probe, which provided for the study with adjustable ultrasonic power 0 W to 800 W and the ultrasonic frequency was 40 kHz, was fixed at the entrance of the primary separation kettle. The optimal separation conditions were determined to be temperature as 15.0 °C, pressure as 18.0 MPa, and ultrasonic power as 360 W of ultrasonic power on the basis of response surface methodology (RSM). Experimental Di-n-butylphthalate (DBP) and Diethyl phthalate (DEP) content were 0.09 mg and 0.04 mg, respectively, which were below the limits for plasticizers. Meanwhile, the total triterpene and ganoderic acid A contents were 6.89 g and 1.10 g, respectively, comparable to conventional supercritical fluid extraction. The experiments with USFS at different power intensities revealed that ultrasonic at a power intensity of 36 W/L and the power density of 0.20 W/cm

Identifiants

pubmed: 37757601
pii: S1350-4177(23)00334-6
doi: 10.1016/j.ultsonch.2023.106622
pmc: PMC10550761
pii:
doi:

Substances chimiques

Plasticizers 0
Triterpenes 0
Dibutyl Phthalate 2286E5R2KE

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

106622

Informations de copyright

Copyright © 2023 The Author(s). Published by Elsevier B.V. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of Competing Interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: Cunyu Li reports financial support was provided by Nanjing University of Chinese Medicine. Cunyu Li reports a relationship with Nanjing University of Chinese Medicine that includes: employment.

Auteurs

Cunyu Li (C)

College of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, China; Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, Nanjing 210023, China. Electronic address: licunyuok@163.com.

Yun Ma (Y)

The Fourth People's Hospital of Taizhou City, Taizhou 225300, China.

Xin Shen (X)

College of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, China.

Wei Chen (W)

Suzhou TCM Hospital Affiliated to Nanjing University of Chinese Medicine, Suzhou 215109, China.

Yuqing Zhou (Y)

Jiangsu Hongshou Biological Engineering Co., Ltd, Haian 226623, China.

Xinglei Zhi (X)

College of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, China. Electronic address: 12317231@qq.com.

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Classifications MeSH