Functional Crosstalk between Discrete Indole Terpenoid Gene Clusters in


Journal

Organic letters
ISSN: 1523-7052
Titre abrégé: Org Lett
Pays: United States
ID NLM: 100890393

Informations de publication

Date de publication:
20 10 2023
Historique:
pmc-release: 05 10 2024
medline: 23 10 2023
pubmed: 6 10 2023
entrez: 5 10 2023
Statut: ppublish

Résumé

Indole terpenoids make up a large group of secondary metabolites that display an enticing array of bioactivities. While indole diterpene (IDT) and rarely indole sesquiterpene (IST) pathways have been found individually in filamentous fungi, here we show that both cluster types are encoded within the genome of

Identifiants

pubmed: 37797949
doi: 10.1021/acs.orglett.3c02412
pmc: PMC10595974
doi:

Substances chimiques

Terpenes 0
Diterpenes 0
Indoles 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

7470-7475

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Auteurs

Taylor R Hibbard (TR)

Ferrier Research Institute, Victoria University of Wellington, Wellington 6012, New Zealand.
Maurice Wilkins Centre for Molecular Biodiscovery, Victoria University of Wellington, Wellington 6012, New Zealand.

Rose M McLellan (RM)

Ferrier Research Institute, Victoria University of Wellington, Wellington 6012, New Zealand.
Maurice Wilkins Centre for Molecular Biodiscovery, Victoria University of Wellington, Wellington 6012, New Zealand.

Luke J Stevenson (LJ)

Ferrier Research Institute, Victoria University of Wellington, Wellington 6012, New Zealand.
Maurice Wilkins Centre for Molecular Biodiscovery, Victoria University of Wellington, Wellington 6012, New Zealand.

Alistair T Richardson (AT)

Ferrier Research Institute, Victoria University of Wellington, Wellington 6012, New Zealand.
Maurice Wilkins Centre for Molecular Biodiscovery, Victoria University of Wellington, Wellington 6012, New Zealand.

Matthew J Nicholson (MJ)

Ferrier Research Institute, Victoria University of Wellington, Wellington 6012, New Zealand.
Wellington UniVentures, Victoria University of Wellington, Wellington 6012, New Zealand.

Emily J Parker (EJ)

Ferrier Research Institute, Victoria University of Wellington, Wellington 6012, New Zealand.
Maurice Wilkins Centre for Molecular Biodiscovery, Victoria University of Wellington, Wellington 6012, New Zealand.

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Classifications MeSH