Preparation and application of a pseudo-templated multi-monomer aflatoxins imprinted polymer.
Aflatoxins
Fluorescence spectroscopy
Molecularly imprinted polymers
Multi-monomer
Pseudo-template
Solid phase extraction
Journal
Mikrochimica acta
ISSN: 1436-5073
Titre abrégé: Mikrochim Acta
Pays: Austria
ID NLM: 7808782
Informations de publication
Date de publication:
18 09 2024
18 09 2024
Historique:
received:
24
05
2024
accepted:
30
08
2024
medline:
18
9
2024
pubmed:
18
9
2024
entrez:
17
9
2024
Statut:
epublish
Résumé
A functional material was developed with specific recognition properties for aflatoxins for pre-processing enrichment and separation in the detection of aflatoxins in Chinese herbal medicines. In the experiment, ethyl coumarin-3-carboxylate, which has a highly similar structure to the oxonaphthalene o-ketone of aflatoxin, was selected as a pseudo-template, zinc acrylate, neutral red derivative, and methacrylic acid, which have complementary functions, were selected as co-monomers to prepare a pseudo-template multifunctional monomer molecularly imprinted polymer (MIP). The MIP obtained under the optimal preparation conditions has a maximum adsorption capacity of 0.036 mg/mg and an imprinting factor of 3.67. The physical property evaluation of the polymers by Fourier infrared spectrometer, scanning electron microscopy, pore size analyzer, thermogravimetric analyzer, and diffuse reflectance spectroscopy showed that the MIP were successfully prepared and porous spherical-like particles were obtained. The synthesized polymer was used as a solid-phase extraction agent for the separation of aflatoxins from the extract of spina date seed. The linear range of the developed method was 10-1000 ng/mL, the limit of detection was 0.36 ng/mL, the limit of quantification was 1.19 ng/mL, and the recoveries of the extracts at the concentration level of 0.2 μg/mL were in the range 88.0-93.4%, with relative standard deviations (RSDs) of 1.97% (n). The results showed that the preparation of MIPs using ethyl coumarin-3-carboxylate as a template was simple, economical, and convenient. It is expected to become a promising functional material for the enrichment and separation aflatoxins from complex matrices.
Identifiants
pubmed: 39289224
doi: 10.1007/s00604-024-06677-7
pii: 10.1007/s00604-024-06677-7
doi:
Substances chimiques
Aflatoxins
0
Molecularly Imprinted Polymers
0
Acrylates
0
Drugs, Chinese Herbal
0
Methacrylates
0
Polymers
0
methacrylic acid
1CS02G8656
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
607Subventions
Organisme : Lianyungang Science and Technology Plan Project (Social Development)
ID : SF2105
Organisme : Open Project of Jiangsu Province Key Laboratory for Active Molecular Screening of Marine Drugs
ID : HY202202
Organisme : Jiangsu Ocean University Talent Introduction Research Fund
ID : KQ21027
Informations de copyright
© 2024. The Author(s), under exclusive licence to Springer-Verlag GmbH Austria, part of Springer Nature.
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