Intricate Evolution of Multifunctional Lipoxygenase in Red Algae.

Rhodophyta / genetics Lipoxygenase / genetics Phylogeny Evolution, Molecular Amino Acid Sequence Molecular Docking Simulation Shewanella / enzymology Mutagenesis, Site-Directed
algae cytochrome P450 fatty acid oxidation lipoxygenase multifunctional enzyme protein evolution

Journal

International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791

Informations de publication

Date de publication:
11 Oct 2024
Historique:
received: 10 09 2024
revised: 02 10 2024
accepted: 09 10 2024
medline: 26 10 2024
pubmed: 26 10 2024
entrez: 26 10 2024
Statut: epublish

Résumé

Lipoxygenases (LOXs) from lower organisms have substrate flexibility and function versatility in fatty acid oxidation, but it is not clear how these LOXs acquired the ability to execute multiple functions within only one catalytic domain. This work studied a multifunctional LOX from red alga

Identifiants

DOI: 10.3390/ijms252010956 PMID: 39456739
pubmed: 39456739
pii: ijms252010956
doi: 10.3390/ijms252010956
pii:
doi:

Substances chimiques

Lipoxygenase EC 1.13.11.12

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Zhejiang Provincial Natural Science Foundation of China
ID : LQ23C190003

Auteurs

Zhujun Zhu (Z)

Marine Drugs and Biological Products Department, Ningbo Institute of Oceanography, Ningbo 315832, China.
State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-Products, Ningbo University, Ningbo 315832, China.
ORCID: 0000-0002-9391-9838

Yanrong Li (Y)

Marine Drugs and Biological Products Department, Ningbo Institute of Oceanography, Ningbo 315832, China.

Xinru Wu (X)

State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-Products, Ningbo University, Ningbo 315832, China.

Jia Li (J)

State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-Products, Ningbo University, Ningbo 315832, China.

Xiaodong Mo (X)

State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-Products, Ningbo University, Ningbo 315832, China.

Xiaojun Yan (X)

Collaborative Innovation Center for Zhejiang Marine High-Efficiency and Healthy Aquaculture, Ningbo University, Ningbo 315832, China.
ORCID: 0000-0003-0257-0157

Haimin Chen (H)

State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-Products, Ningbo University, Ningbo 315832, China.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Rhodophyta › Intricate Evolution of Multifunctional...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Métalloprotéines › Protéines de liaison au fer › Protéines à fer non hème › Lipoxygénases › Lipoxygenase › Intricate Evolution of Multifunctional...
questionsmedicales.fr › Sciences de l'information › Phylogenèse › Intricate Evolution of Multifunctional...
questionsmedicales.fr › Phénomènes biologiques › Évolution biologique › Évolution moléculaire › Intricate Evolution of Multifunctional...
questionsmedicales.fr › Sciences de l'information › Sources d'information › Services d'information › Documentation › Données de séquences moléculaires › Séquence d'acides aminés › Intricate Evolution of Multifunctional...
questionsmedicales.fr › Sciences de l'information › Méthodologies informatiques › Simulation numérique › Simulation de docking moléculaire › Intricate Evolution of Multifunctional...
questionsmedicales.fr › Bactéries › Proteobacteria › Gammaproteobacteria › Alteromonadaceae › Shewanella › Intricate Evolution of Multifunctional...
questionsmedicales.fr › Techniques d'investigation › Techniques génétiques › Génie génétique › Ingénierie des protéines › Mutagenèse dirigée › Intricate Evolution of Multifunctional...