Ciro Milite

Publications (15)

Turning Nonselective Inhibitors of Type I Protein Arginine Methyltransferases into Potent and Selective Inhibitors of Protein Arginine Methyltransferase 4 through a Deconstruction-Reconstruction and Fragment-Growing Approach.

Journal of medicinal chemistry

Avec: Giulia Iannelli , Nils Marechal , Vincent Cura , Luc Bonnefond , Nathalie Troffer-Charlier , Alessandra Feoli , Donatella Rescigno , Yalong Wang , Alessandra Cipriano , Monica Viviano , Mark T Bedford , Jean Cavarelli , Sabrina Castellano , Gianluca Sbardella

NADPH Oxidases: From Molecular Mechanisms to Current Inhibitors.

Journal of medicinal chemistry

Avec: Alessandra Cipriano , Monica Viviano , Alessandra Feoli , Giuliana Sarno , Sabrina Castellano , Gianluca Sbardella

Identification of a Protein Arginine Methyltransferase 7 (PRMT7)/Protein Arginine Methyltransferase 9 (PRMT9) Inhibitor.

Journal of medicinal chemistry

Avec: Alessandra Feoli , Giulia Iannelli , Alessandra Cipriano , Lei Shen , Zhihao Wang , Andrea Hadjikyriacou , Troy L Lowe , Cyrus Safaeipour , Monica Viviano , Giuliana Sarno , Elva Morretta , Maria Chiara Monti , Yanzhong Yang , Steven G Clarke , Sandro Cosconati , Sabrina Castellano , Gianluca Sbardella

Prodrug Approach to Exploit (S) Alanine as Arginine Mimic Moiety in the Development of Protein Arginine Methyltransferase 4 Inhibitors.

ChemMedChem

Avec: Giuliana Sarno , Ida Pacilio , Agostino Cianciulli , Monica Viviano , Giulia Iannelli , Erica Gazzillo , Alessandra Feoli , Alessandra Cipriano , Maria Giovanna Chini , Sabrina Castellano , Giuseppe Bifulco , Gianluca Sbardella

The Lysine Acetyltransferase PCAF Functionally Interacts with Estrogen Receptor Alpha in the Hippocampus of Gonadally Intact Male - but not Female - Rats to Enhance Short-term Memory.

The Journal of neuroscience : the official journal of the Society for Neuroscience

Avec: Krista A Mitchnick , Kate Nicholson , Cassidy Wideman , Kristen Jardine , Rhiannon Jamieson-Williams , Samantha D Creighton , Allison Lacoursiere , Sabrina Castellano , Gianluca Sbardella , Neil J MacLusky , Elena Choleris , Boyer D Winters

Reverse transcriptase inhibitors promote the remodelling of nuclear architecture and induce autophagy in prostate cancer cells.

Cancer letters

Avec: Cristina Bellisai , Ilaria Sciamanna , Paola Rovella , Daniela Giovannini , Mirko Baranzini , Giusj Monia Pugliese , Mohammad Salik Zeya Ansari , Paola Sinibaldi-Vallebona , Roberto Cirilli , Gianluca Sbardella , Pietro Pichierri , Daniela Trisciuoglio , Patrizia Lavia , Annalucia Serafino , Corrado Spadafora

Novel 2-substituted-benzimidazole-6-sulfonamides as carbonic anhydrase inhibitors: synthesis, biological evaluation against isoforms I, II, IX and XII and molecular docking studies.

Journal of enzyme inhibition and medicinal chemistry

Avec: Giorgio Amendola , Alessio Nocentini , Silvia Bua , Alessandra Cipriano , Elisabetta Barresi , Alessandra Feoli , Ettore Novellino , Federico Da Settimo , Claudiu T Supuran , Sabrina Castellano , Sandro Cosconati , Sabrina Taliani

Reverse transcriptase inhibition potentiates target therapy in BRAF-mutant melanomas: effects on cell proliferation, apoptosis, DNA-damage, ROS induction and mitochondrial membrane depolarization.

Cell communication and signaling : CCS

Avec: Luigi Fattore , Debora Malpicci , Sabrina Castellano , Gianluca Sbardella , Gerardo Botti , Paolo A Ascierto , Rita Mancini , Gennaro Ciliberto

Age-dependent attenuation of spatial memory deficits by the histone acetyltransferase p300/CBP-associated factor (PCAF) in 3xTG Alzheimer's disease mice.

Learning & memory (Cold Spring Harbor, N.Y.)

Avec: Samantha D Creighton , Kristen H Jardine , Alexa Desimone , Megan Zmetana , Sabrina Castellano , Gianluca Sbardella , Boyer D Winters

Discovery of a Novel Chemotype of Histone Lysine Methyltransferase EHMT1/2 (GLP/G9a) Inhibitors: Rational Design, Synthesis, Biological Evaluation, and Co-crystal Structure.

Journal of medicinal chemistry

Avec: Alessandra Feoli , John R Horton , Donatella Rescigno , Alessandra Cipriano , Vincenzo Pisapia , Monica Viviano , Giacomo Pepe , Giorgio Amendola , Ettore Novellino , Sandro Cosconati , Xiaodong Cheng , Sabrina Castellano , Gianluca Sbardella

Benzothiopyranoindole- and pyridothiopyranoindole-based antiproliferative agents targeting topoisomerases.

European journal of medicinal chemistry

Avec: Silvia Salerno , Valeria La Pietra , Mariafrancesca Hyeraci , Sabrina Taliani , Marco Robello , Elisabetta Barresi , Francesca Simorini , Aída Nelly García-Argáez , Luciana Marinelli , Ettore Novellino , Federico Da Settimo , Anna Maria Marini , Lisa Dalla Via

Patent evaluation of WO2019209182 (A1) 2019-10-31 (Conjugated Oligoelectrolytes as Antimicrobial Agents).

Expert opinion on therapeutic patents

Avec:

Lysine methyltransferase inhibitors: where we are now.

RSC chemical biology

Avec: Alessandra Feoli , Monica Viviano , Alessandra Cipriano , Sabrina Castellano , Gianluca Sbardella

Successes and challenges in the development of BD1-selective BET inhibitors: a patent review.

Expert opinion on therapeutic patents

Avec: Monica Viviano , Alessandra Cipriano , Emanuele Fabbrizi , Alessandra Feoli , Sabrina Castellano , Gianluca Sbardella , Antonello Mai , Dante Rotili

Discovery of Benzo[d]imidazole-6-sulfonamides as Bromodomain and Extra-Terminal Domain (BET) Inhibitors with Selectivity for the First Bromodomain.

ChemMedChem

Avec: Alessandra Cipriano , Alessandra Feoli , Monica Viviano , Giacomo Pepe , Pietro Campiglia , Giuliana Sarno , Sarah Picaud , Satomi Imaide , Nikolai Makukhin , Panagis Filippakopoulos , Alessio Ciulli , Sabrina Castellano , Gianluca Sbardella

Réseau de co-auteurs

Sabrina Castellano 12 collaborations

Gianluca Sbardella 12 collaborations

Alessandra Feoli 9 collaborations

Alessandra Cipriano 9 collaborations

Monica Viviano 8 collaborations

Giuliana Sarno 4 collaborations

Giulia Iannelli 3 collaborations

Sandro Cosconati 3 collaborations

Ettore Novellino 3 collaborations

Donatella Rescigno 2 collaborations

Samantha D Creighton 2 collaborations

Boyer D Winters 2 collaborations

Giorgio Amendola 2 collaborations

Elisabetta Barresi 2 collaborations

Federico Da Settimo 2 collaborations

Sabrina Taliani 2 collaborations

Giacomo Pepe 2 collaborations

Nils Marechal 1 collaboration

Vincent Cura 1 collaboration

Luc Bonnefond 1 collaboration

Nathalie Troffer-Charlier 1 collaboration

Yalong Wang 1 collaboration

Mark T Bedford 1 collaboration

Jean Cavarelli 1 collaboration

Lei Shen 1 collaboration

Zhihao Wang 1 collaboration

Andrea Hadjikyriacou 1 collaboration

Troy L Lowe 1 collaboration

Cyrus Safaeipour 1 collaboration

Elva Morretta 1 collaboration

Maria Chiara Monti 1 collaboration

Yanzhong Yang 1 collaboration

Steven G Clarke 1 collaboration

Ida Pacilio 1 collaboration

Agostino Cianciulli 1 collaboration

Erica Gazzillo 1 collaboration

Maria Giovanna Chini 1 collaboration

Giuseppe Bifulco 1 collaboration

Krista A Mitchnick 1 collaboration

Kate Nicholson 1 collaboration

Cassidy Wideman 1 collaboration

Kristen Jardine 1 collaboration

Rhiannon Jamieson-Williams 1 collaboration

Allison Lacoursiere 1 collaboration

Neil J MacLusky 1 collaboration

Elena Choleris 1 collaboration

Cristina Bellisai 1 collaboration

Ilaria Sciamanna 1 collaboration

Paola Rovella 1 collaboration

Daniela Giovannini 1 collaboration

Mirko Baranzini 1 collaboration

Giusj Monia Pugliese 1 collaboration

Mohammad Salik Zeya Ansari 1 collaboration

Paola Sinibaldi-Vallebona 1 collaboration

Roberto Cirilli 1 collaboration

Pietro Pichierri 1 collaboration

Daniela Trisciuoglio 1 collaboration

Patrizia Lavia 1 collaboration

Annalucia Serafino 1 collaboration

Corrado Spadafora 1 collaboration

Alessio Nocentini 1 collaboration

Silvia Bua 1 collaboration

Claudiu T Supuran 1 collaboration

Luigi Fattore 1 collaboration

Debora Malpicci 1 collaboration

Gerardo Botti 1 collaboration

Paolo A Ascierto 1 collaboration

Rita Mancini 1 collaboration

Gennaro Ciliberto 1 collaboration

Kristen H Jardine 1 collaboration

Alexa Desimone 1 collaboration

Megan Zmetana 1 collaboration

John R Horton 1 collaboration

Vincenzo Pisapia 1 collaboration

Xiaodong Cheng 1 collaboration

Silvia Salerno 1 collaboration

Valeria La Pietra 1 collaboration

Mariafrancesca Hyeraci 1 collaboration

Marco Robello 1 collaboration

Francesca Simorini 1 collaboration

Aída Nelly García-Argáez 1 collaboration

Luciana Marinelli 1 collaboration

Anna Maria Marini 1 collaboration

Lisa Dalla Via 1 collaboration

Emanuele Fabbrizi 1 collaboration

Antonello Mai 1 collaboration

Dante Rotili 1 collaboration

Pietro Campiglia 1 collaboration

Sarah Picaud 1 collaboration

Satomi Imaide 1 collaboration

Nikolai Makukhin 1 collaboration

Panagis Filippakopoulos 1 collaboration

Alessio Ciulli 1 collaboration