A Denadai-Souza

Affiliations

Translational Research Center for Gastrointestinal Disorders, Department of Chronic Diseases, Metabolism and Ageing, Katholieke Universiteit Leuven , Leuven , Belgium.

Publications (17)

Histamine-mediated potentiation of transient receptor potential (TRP) ankyrin 1 and TRP vanilloid 4 signaling in submucosal neurons in patients with irritable bowel syndrome.

American journal of physiology. Gastrointestinal and liver physiology

Avec: D Balemans , J Aguilera-Lizarraga , M V Florens , P Jain , A Denadai-Souza , M F Viola , Y A Alpizar , S Van Der Merwe , P Vanden Berghe , K Talavera , S Vanner , M M Wouters , G E Boeckxstaens

Treatment of non-constipated irritable bowel syndrome with the histamine 1 receptor antagonist ebastine: a randomised, double-blind, placebo-controlled trial.

Gut

Avec: Lisse Decraecker , Danny De Looze , David P Hirsch , Heiko De Schepper , Joris Arts , Philip Caenepeel , Albert J Bredenoord , Jeroen Kolkman , Koen Bellens , Kim Van Beek , Fedrica Pia , Willy Peetermans , Tim Vanuytsel , Alexandre Denadai-Souza , Ann Belmans , Guy Boeckxstaens

Tumor necrosis factor receptor-associated factor 6 interaction with alpha-synuclein enhances cell death through the Nuclear Factor-kB pathway.

IBRO reports

Avec: Lidia M Yshii , Adriana O Manfiolli , Alexandre Denadai-Souza , Paula F Kinoshita , Marcelo D Gomes , Cristoforo Scavone

Active thrombin produced by the intestinal epithelium controls mucosal biofilms.

Nature communications

Avec: Jean-Paul Motta , Alexandre Denadai-Souza , David Sagnat , Laura Guiraud , Anissa Edir , Chrystelle Bonnart , Mireille Sebbag , Perrine Rousset , Ariane Lapeyre , Carine Seguy , Noa Mathurine-Thomas , Heather J Galipeau , Delphine Bonnet , Laurent Alric , Andre G Buret , John L Wallace , Antoine Dufour , Elena F Verdu , Morley D Hollenberg , Eric Oswald , Matteo Serino , Celine Deraison , Nathalie Vergnolle

Protein disulfide isomerase-mediated transcriptional upregulation of Nox1 contributes to vascular dysfunction in hypertension.

Journal of hypertension

Avec: Livia De Lucca Camargo , Silvia Cellone Trevelin , Guilherme Henrique Gatti da Silva , Ana Alice Dos Santos Dias , Maria Aparecida Oliveira , Olga Mikhaylichenko , Aline C D Androwiki , Celio Xavier Dos Santos , Lisa-Marie Holbrook , Graziela Scalianti Ceravolo , Alexandre Denadai-Souza , Izabela Martina Ramos Ribeiro , Simone Sartoretto , Francisco Rafael Martins Laurindo , Patricia Pereira Coltri , Vagner Roberto Antunes , Rhian Touyz , Francis J Miller , Ajay M Shah , Lucia Rossetti Lopes

A Roadmap for the Human Gut Cell Atlas.

Nature reviews. Gastroenterology & hepatology

Avec: Matthias Zilbauer , Kylie R James , Mandeep Kaur , Sebastian Pott , Zhixin Li , Albert Burger , Jay R Thiagarajah , Joseph Burclaff , Frode L Jahnsen , Francesca Perrone , Alexander D Ross , Gianluca Matteoli , Nathalie Stakenborg , Tomohisa Sujino , Andreas Moor , Raquel Bartolome-Casado , Espen S Bækkevold , Ran Zhou , Bingqing Xie , Ken S Lau , Shahida Din , Scott T Magness , Qiuming Yao , Semir Beyaz , Mark Arends , Alexandre Denadai-Souza , Lori A Coburn , Jellert T Gaublomme , Richard Baldock , Irene Papatheodorou , Jose Ordovas-Montanes , Guy Boeckxstaens , Anna Hupalowska , Sarah A Teichmann , Aviv Regev , Ramnik J Xavier , Alison Simmons , Michael P Snyder , Keith T Wilson , Auteur inconnu , Auteur inconnu

The Interplay Between Genetic Risk Factors and Proteolytic Dysregulation in the Pathophysiology of Inflammatory Bowel Disease.

Journal of Crohn's & colitis

Avec: Núria Solà-Tapias , Nathalie Vergnolle , Alexandre Denadai-Souza , Frédérick Barreau

FAK alternative splice mRNA variants expression pattern in colorectal cancer.

International journal of cancer

Avec: Christel Devaud , Anne-Françoise Tilkin-Mariamé , Alix Vignolle-Vidoni , Philippine Souleres , Alexandre Denadai-Souza , Corinne Rolland , Christine Duthoit , Catherine Blanpied , Sophie Chabot , Pascale Bouillé , Philippe Lluel , Nathalie Vergnolle , Claire Racaud-Sultan , Audrey Ferrand

Sexual dimorphism in PAR

Biology of sex differences

Avec: Julie Noguerol , Pierre-Jean Roustan , Mikael N'Taye , Léo Delcombel , Corinne Rolland , Laura Guiraud , David Sagnat , Anissa Edir , Chrystelle Bonnart , Alexandre Denadai-Souza , Céline Deraison , Nathalie Vergnolle , Claire Racaud-Sultan

Increased Mucosal Thrombin is Associated with Crohn's Disease and Causes Inflammatory Damage through Protease-activated Receptors Activation.

Journal of Crohn's & colitis

Avec: Jean-Paul Motta , Simone Palese , Carmine Giorgio , Kevin Chapman , Alexandre Denadai-Souza , Perrine Rousset , David Sagnat , Laura Guiraud , Anissa Edir , Carine Seguy , Laurent Alric , Delphine Bonnet , Barbara Bournet , Louis Buscail , Cyrielle Gilletta , Andre G Buret , John L Wallace , Morley D Hollenberg , Eric Oswald , Elisabetta Barocelli , Sylvie Le Grand , Bruno Le Grand , Celine Deraison , Nathalie Vergnolle

Chemically diverse activity-based probes with unexpected inhibitory mechanisms targeting trypsin-like serine proteases.

Frontiers in chemistry

Avec: Alba Ramos-Llorca , Lisse Decraecker , Valérie M Y Cacheux , Irena Zeiburlina , Michelle De Bruyn , Louise Battut , Carlos Moreno-Cinos , Davide Ceradini , Eric Espinosa , Gilles Dietrich , Maya Berg , Ingrid De Meester , Pieter Van Der Veken , Guy Boeckxstaens , Anne-Marie Lambeir , Alexandre Denadai-Souza , Koen Augustyns

The potential anti-inflammatory and anti-nociceptive effects of rat hemopressin (PVNFKFLSH) in experimental arthritis.

European journal of pharmacology

Avec: Livia L Camargo , Alexandre Denadai-Souza , Lidia M Yshii , Carla Lima , Simone A Teixeira , Anderson R A Cerqueira , Mayara C F Gewehr , Elizabeth S Fernandes , André A Schenka , Marcelo N Muscará , Emer S Ferro , Soraia K P Costa

Local immune response to food antigens drives meal-induced abdominal pain.

Nature

Avec: Javier Aguilera-Lizarraga , Morgane V Florens , Maria Francesca Viola , Piyush Jain , Lisse Decraecker , Iris Appeltans , Maria Cuende-Estevez , Naomi Fabre , Kim Van Beek , Eluisa Perna , Dafne Balemans , Nathalie Stakenborg , Stavroula Theofanous , Goele Bosmans , Stéphanie U Mondelaers , Gianluca Matteoli , Sales Ibiza Martínez , Cintya Lopez-Lopez , Josue Jaramillo-Polanco , Karel Talavera , Yeranddy A Alpizar , Thorsten B Feyerabend , Hans-Reimer Rodewald , Ricard Farre , Frank A Redegeld , Jiyeon Si , Jeroen Raes , Christine Breynaert , Rik Schrijvers , Cédric Bosteels , Bart N Lambrecht , Scott D Boyd , Ramona A Hoh , Deirdre Cabooter , Maxim Nelis , Patrick Augustijns , Sven Hendrix , Jessica Strid , Raf Bisschops , David E Reed , Stephen J Vanner , Alexandre Denadai-Souza , Mira M Wouters , Guy E Boeckxstaens

Colitis Linked to Endoplasmic Reticulum Stress Induces Trypsin Activity Affecting Epithelial Functions.

Journal of Crohn's & colitis

Avec: Núria Solà Tapias , Alexandre Denadai-Souza , Claire Rolland-Fourcade , Muriel Quaranta-Nicaise , Catherine Blanpied , Marlène Marcellin , Anissa Edir , Corinne Rolland , Carla Cirillo , Gilles Dietrich , Laurent Alric , Guillaume Portier , Sylvain Kirzin , Delphine Bonnet , Emmanuel Mas , Odile Burlet-Schiltz , Céline Deraison , Chrystelle Bonnart , Nathalie Vergnolle , Frédérick Barreau

Inhibition of Serine Proteases as a Novel Therapeutic Strategy for Abdominal Pain in IBS.

Frontiers in physiology

Avec: Lisse Decraecker , Guy Boeckxstaens , Alexandre Denadai-Souza

Spatially resolved transcriptomic profiling of degraded and challenging fresh frozen samples.

Nature communications

Avec: Reza Mirzazadeh , Zaneta Andrusivova , Ludvig Larsson , Phillip T Newton , Leire Alonso Galicia , Xesús M Abalo , Mahtab Avijgan , Linda Kvastad , Alexandre Denadai-Souza , Nathalie Stakenborg , Alexandra B Firsova , Alia Shamikh , Aleksandra Jurek , Niklas Schultz , Monica Nistér , Christos Samakovlis , Guy Boeckxstaens , Joakim Lundeberg

Fecal Proteolytic Bacteria and Staphylococcal Superantigens are Associated with Abdominal Pain Severity in Irritable Bowel Syndrome.

The American journal of gastroenterology

Avec: Runze Quan , Lisse Decraecker , Iris Appeltans , María Cuende-Estévez , Samuel Van Remoortel , Javier Aguilera-Lizarraga , Zheng Wang , Gareth Hicks , Jill Wykosky , Peter McLean , Alexandre Denadai-Souza , Hind Hussein , Guy E Boeckxstaens

Réseau de co-auteurs

Alexandre Denadai-Souza 16 collaborations

Nathalie Vergnolle 6 collaborations

Lisse Decraecker 5 collaborations

Guy Boeckxstaens 5 collaborations

Anissa Edir 4 collaborations

David Sagnat 3 collaborations

Laura Guiraud 3 collaborations

Chrystelle Bonnart 3 collaborations

Delphine Bonnet 3 collaborations

Laurent Alric 3 collaborations

Nathalie Stakenborg 3 collaborations

Corinne Rolland 3 collaborations

Kim Van Beek 2 collaborations

Lidia M Yshii 2 collaborations

Jean-Paul Motta 2 collaborations

Perrine Rousset 2 collaborations

Carine Seguy 2 collaborations

Andre G Buret 2 collaborations

John L Wallace 2 collaborations

Morley D Hollenberg 2 collaborations

Eric Oswald 2 collaborations

Celine Deraison 2 collaborations

Gianluca Matteoli 2 collaborations

None None 2 collaborations

Frédérick Barreau 2 collaborations

Catherine Blanpied 2 collaborations

Claire Racaud-Sultan 2 collaborations

Céline Deraison 2 collaborations

Gilles Dietrich 2 collaborations

Javier Aguilera-Lizarraga 2 collaborations

Iris Appeltans 2 collaborations

Guy E Boeckxstaens 2 collaborations

D Balemans 1 collaboration

J Aguilera-Lizarraga 1 collaboration

M V Florens 1 collaboration

P Jain 1 collaboration

M F Viola 1 collaboration

Y A Alpizar 1 collaboration

S Van Der Merwe 1 collaboration

P Vanden Berghe 1 collaboration

K Talavera 1 collaboration

S Vanner 1 collaboration

M M Wouters 1 collaboration

G E Boeckxstaens 1 collaboration

Danny De Looze 1 collaboration

David P Hirsch 1 collaboration

Heiko De Schepper 1 collaboration

Joris Arts 1 collaboration

Philip Caenepeel 1 collaboration

Albert J Bredenoord 1 collaboration

Jeroen Kolkman 1 collaboration

Koen Bellens 1 collaboration

Fedrica Pia 1 collaboration

Willy Peetermans 1 collaboration

Tim Vanuytsel 1 collaboration

Ann Belmans 1 collaboration

Adriana O Manfiolli 1 collaboration

Paula F Kinoshita 1 collaboration

Marcelo D Gomes 1 collaboration

Cristoforo Scavone 1 collaboration

Mireille Sebbag 1 collaboration

Ariane Lapeyre 1 collaboration

Noa Mathurine-Thomas 1 collaboration

Heather J Galipeau 1 collaboration

Antoine Dufour 1 collaboration

Elena F Verdu 1 collaboration

Matteo Serino 1 collaboration

Livia De Lucca Camargo 1 collaboration

Silvia Cellone Trevelin 1 collaboration

Guilherme Henrique Gatti da Silva 1 collaboration

Ana Alice Dos Santos Dias 1 collaboration

Maria Aparecida Oliveira 1 collaboration

Olga Mikhaylichenko 1 collaboration

Aline C D Androwiki 1 collaboration

Celio Xavier Dos Santos 1 collaboration

Lisa-Marie Holbrook 1 collaboration

Graziela Scalianti Ceravolo 1 collaboration

Izabela Martina Ramos Ribeiro 1 collaboration

Simone Sartoretto 1 collaboration

Francisco Rafael Martins Laurindo 1 collaboration

Patricia Pereira Coltri 1 collaboration

Vagner Roberto Antunes 1 collaboration

Rhian Touyz 1 collaboration

Francis J Miller 1 collaboration

Ajay M Shah 1 collaboration

Lucia Rossetti Lopes 1 collaboration

Matthias Zilbauer 1 collaboration

Kylie R James 1 collaboration

Mandeep Kaur 1 collaboration

Sebastian Pott 1 collaboration

Zhixin Li 1 collaboration

Albert Burger 1 collaboration

Jay R Thiagarajah 1 collaboration

Joseph Burclaff 1 collaboration

Frode L Jahnsen 1 collaboration

Francesca Perrone 1 collaboration

Alexander D Ross 1 collaboration

Tomohisa Sujino 1 collaboration

Andreas Moor 1 collaboration

Raquel Bartolome-Casado 1 collaboration

Espen S Bækkevold 1 collaboration

Ran Zhou 1 collaboration

Bingqing Xie 1 collaboration

Ken S Lau 1 collaboration

Shahida Din 1 collaboration

Scott T Magness 1 collaboration

Qiuming Yao 1 collaboration

Semir Beyaz 1 collaboration

Mark Arends 1 collaboration

Lori A Coburn 1 collaboration

Jellert T Gaublomme 1 collaboration

Richard Baldock 1 collaboration

Irene Papatheodorou 1 collaboration

Jose Ordovas-Montanes 1 collaboration

Anna Hupalowska 1 collaboration

Sarah A Teichmann 1 collaboration

Aviv Regev 1 collaboration

Ramnik J Xavier 1 collaboration

Alison Simmons 1 collaboration

Michael P Snyder 1 collaboration

Keith T Wilson 1 collaboration

Núria Solà-Tapias 1 collaboration

Christel Devaud 1 collaboration

Anne-Françoise Tilkin-Mariamé 1 collaboration

Alix Vignolle-Vidoni 1 collaboration

Philippine Souleres 1 collaboration

Christine Duthoit 1 collaboration

Sophie Chabot 1 collaboration

Pascale Bouillé 1 collaboration

Philippe Lluel 1 collaboration

Audrey Ferrand 1 collaboration

Julie Noguerol 1 collaboration

Pierre-Jean Roustan 1 collaboration

Mikael N'Taye 1 collaboration

Léo Delcombel 1 collaboration

Simone Palese 1 collaboration

Carmine Giorgio 1 collaboration

Kevin Chapman 1 collaboration

Barbara Bournet 1 collaboration

Louis Buscail 1 collaboration

Cyrielle Gilletta 1 collaboration

Elisabetta Barocelli 1 collaboration

Sylvie Le Grand 1 collaboration

Bruno Le Grand 1 collaboration

Alba Ramos-Llorca 1 collaboration

Valérie M Y Cacheux 1 collaboration

Irena Zeiburlina 1 collaboration

Michelle De Bruyn 1 collaboration

Louise Battut 1 collaboration

Carlos Moreno-Cinos 1 collaboration

Davide Ceradini 1 collaboration

Eric Espinosa 1 collaboration

Maya Berg 1 collaboration

Ingrid De Meester 1 collaboration

Pieter Van Der Veken 1 collaboration

Anne-Marie Lambeir 1 collaboration

Koen Augustyns 1 collaboration

Livia L Camargo 1 collaboration

Carla Lima 1 collaboration

Simone A Teixeira 1 collaboration

Anderson R A Cerqueira 1 collaboration

Mayara C F Gewehr 1 collaboration

Elizabeth S Fernandes 1 collaboration

André A Schenka 1 collaboration

Marcelo N Muscará 1 collaboration

Emer S Ferro 1 collaboration

Soraia K P Costa 1 collaboration

Morgane V Florens 1 collaboration

Maria Francesca Viola 1 collaboration

Piyush Jain 1 collaboration

Maria Cuende-Estevez 1 collaboration

Naomi Fabre 1 collaboration

Eluisa Perna 1 collaboration

Dafne Balemans 1 collaboration

Stavroula Theofanous 1 collaboration

Goele Bosmans 1 collaboration

Stéphanie U Mondelaers 1 collaboration

Sales Ibiza Martínez 1 collaboration

Cintya Lopez-Lopez 1 collaboration

Josue Jaramillo-Polanco 1 collaboration

Karel Talavera 1 collaboration

Yeranddy A Alpizar 1 collaboration

Thorsten B Feyerabend 1 collaboration

Hans-Reimer Rodewald 1 collaboration

Ricard Farre 1 collaboration

Frank A Redegeld 1 collaboration

Jiyeon Si 1 collaboration

Jeroen Raes 1 collaboration

Christine Breynaert 1 collaboration

Rik Schrijvers 1 collaboration

Cédric Bosteels 1 collaboration

Bart N Lambrecht 1 collaboration

Scott D Boyd 1 collaboration

Ramona A Hoh 1 collaboration

Deirdre Cabooter 1 collaboration

Maxim Nelis 1 collaboration

Patrick Augustijns 1 collaboration

Sven Hendrix 1 collaboration

Jessica Strid 1 collaboration

Raf Bisschops 1 collaboration

David E Reed 1 collaboration

Stephen J Vanner 1 collaboration

Mira M Wouters 1 collaboration

Núria Solà Tapias 1 collaboration

Claire Rolland-Fourcade 1 collaboration

Muriel Quaranta-Nicaise 1 collaboration

Marlène Marcellin 1 collaboration

Carla Cirillo 1 collaboration

Guillaume Portier 1 collaboration

Sylvain Kirzin 1 collaboration

Emmanuel Mas 1 collaboration

Odile Burlet-Schiltz 1 collaboration

Reza Mirzazadeh 1 collaboration

Zaneta Andrusivova 1 collaboration

Ludvig Larsson 1 collaboration

Phillip T Newton 1 collaboration

Leire Alonso Galicia 1 collaboration

Xesús M Abalo 1 collaboration

Mahtab Avijgan 1 collaboration

Linda Kvastad 1 collaboration

Alexandra B Firsova 1 collaboration

Alia Shamikh 1 collaboration

Aleksandra Jurek 1 collaboration

Niklas Schultz 1 collaboration

Monica Nistér 1 collaboration

Christos Samakovlis 1 collaboration

Joakim Lundeberg 1 collaboration

Runze Quan 1 collaboration

María Cuende-Estévez 1 collaboration

Samuel Van Remoortel 1 collaboration

Zheng Wang 1 collaboration

Gareth Hicks 1 collaboration

Jill Wykosky 1 collaboration

Peter McLean 1 collaboration

Hind Hussein 1 collaboration