A Ebneth

Affiliations

Neuroscience Therapeutic Area, Janssen Research & Development, A Division of Janssen Pharmaceutica NV, UK.

Publications (13)

The EBiSC iPSC bank for disease studies.

Stem cell research

Avec: Rachel Steeg , Julia C Neubauer , Sabine C Müller , Andreas Ebneth , Heiko Zimmermann

Development of a fully human assay combining NGN2-inducible neurons co-cultured with iPSC-derived astrocytes amenable for electrophysiological studies.

Stem cell research

Avec: Pei-Yu Shih , Mohamed Kreir , Devesh Kumar , Frederik Seibt , Francisco Pestana , Benjamin Schmid , Bjørn Holst , Christian Clausen , Rachel Steeg , Benjamin Fischer , Juan Pita-Almenar , Andreas Ebneth , Alfredo Cabrera-Socorro

Small Molecule Binding to Alzheimer Risk Factor CD33 Promotes Aβ Phagocytosis.

iScience

Avec: Luke A Miles , Stefan J Hermans , Gabriela A N Crespi , Jonathan H Gooi , Larissa Doughty , Tracy L Nero , Jasmina Markulić , Andreas Ebneth , Berthold Wroblowski , Daniel Oehlrich , Andrés A Trabanco , Marie-Laure Rives , Ines Royaux , Nancy C Hancock , Michael W Parker

Scalable expansion of iPSC and their derivatives across multiple lineages.

Reproductive toxicology (Elmsford, N.Y.)

Avec: Chee Keong Kwok , Isabelle Sébastien , Krithika Hariharan , Ina Meiser , Jeanette Wihan , Saskia Altmaier , Isabell Karnatz , Dominic Bauer , Benjamin Fischer , Alexander Feile , Alfredo Cabrera-Socorro , Mikkel Rasmussen , Bjørn Holst , Julia C Neubauer , Christian Clausen , Catherine Verfaillie , Andreas Ebneth , Mattias Hansson , Rachel Steeg , Heiko Zimmermann

Diazaspirononane Nonsaccharide Inhibitors of O-GlcNAcase (OGA) for the Treatment of Neurodegenerative Disorders.

Journal of medicinal chemistry

Avec: Carlos M Martínez-Viturro , Andrés A Trabanco , Jordi Royes , Elena Fernández , Gary Tresadern , Juan A Vega , Alcira Del Cerro , Francisca Delgado , Aránzazu García Molina , Fulgencio Tovar , Paul Shaffer , Andreas Ebneth , Alexis Bretteville , Liesbeth Mertens , Marijke Somers , Jose M Alonso , José M Bartolomé-Nebreda

Generation of a set of isogenic iPSC lines carrying all APOE genetic variants (Ɛ2/Ɛ3/Ɛ4) and knock-out for the study of APOE biology in health and disease.

Stem cell research

Avec: Benjamin Schmid , Bjørn Holst , Christian Clausen , Lamiaa Bahnassawy , Peter Reinhardt , Margot H M Bakker , Eva Díaz-Guerra , Carlos Vicario , Pamela V Martino-Adami , Michaela Thoenes , Alfredo Ramirez , Klaus Fliessbach , Clara Grezella , Oliver Brüstle , Michael Peitz , Andreas Ebneth , Alfredo Cabrera-Socorro

Imaging Mutant Huntingtin Aggregates: Development of a Potential PET Ligand.

Journal of medicinal chemistry

Avec: Longbin Liu , Michael E Prime , Matt R Lee , Vinod Khetarpal , Christopher J Brown , Peter D Johnson , Patricia Miranda-Azpiazu , Xuemei Chen , Daniel Clark-Frew , Samuel Coe , Randall Davis , Anthony Dickie , Andreas Ebneth , Simone Esposito , Elise Gadouleau , Xinjie Gai , Sebastien Galan , Samantha Green , Catherine Greenaway , Paul Giles , Christer Halldin , Sarah Hayes , Todd Herbst , Frank Herrmann , Manuela Heßmann , Zhisheng Jia , Alexander Kiselyov , Adrian Kotey , Thomas Krulle , John E Mangette , Richard W Marston , Sergio Menta , Matthew R Mills , Edith Monteagudo , Sangram Nag , Martina Nibbio , Laura Orsatti , Sabine Schaertl , Christoph Scheich , Joanne Sproston , Vladimir Stepanov , Marie Svedberg , Akihiro Takano , Malcolm Taylor , Wayne Thomas , Miklós Toth , Darshan Vaidya , Katarina Vanräs , Derek Weddell , Ian Wigginton , John Wityak , Ladislav Mrzljak , Ignacio Munoz-Sanjuan , Jonathan A Bard , Celia Dominguez

Deploying human pluripotent stem cells to treat central nervous system disorders: facts, challenges and realising the potential.

Stem cell research

Avec: Timothy E Allsopp , Andreas Ebneth , Alfredo Cabrera-Socorro

Generation of two gene edited iPSC-lines carrying a DOX-inducible NGN2 expression cassette with and without GFP in the AAVS1 locus.

Stem cell research

Avec: Benjamin Schmid , Bjørn Holst , Ulla Poulsen , Ida Jørring , Christian Clausen , M Rasmussen , Ulrike A Mau-Holzmann , Rachel Steeg , Hugh Nuthall , A Ebneth , A Cabrera-Socorro

SOX9-induced Generation of Functional Astrocytes Supporting Neuronal Maturation in an All-human System.

Stem cell reviews and reports

Avec: Katrien Neyrinck , Johanna Van Den Daele , Tim Vervliet , Jonathan De Smedt , Keimpe Wierda , Melissa Nijs , Tom Vanbokhoven , Astrid D'hondt , Mélanie Planque , Sarah-Maria Fendt , Pei-Yu Shih , Frederik Seibt , Juan Pita Almenar , Mohamed Kreir , Devesh Kumar , Vania Broccoli , Geert Bultynck , Andreas Ebneth , Alfredo Cabrera-Socorro , Catherine Verfaillie

Generation of a set of isogenic, gene-edited iPSC lines homozygous for all main APOE variants and an APOE knock-out line.

Stem cell research

Avec: Benjamin Schmid , Kennie R Prehn , Natakarn Nimsanor , Blanca Irene Aldana Garcia , Ulla Poulsen , Ida Jørring , Mikkel A Rasmussen , Christian Clausen , Ulrike A Mau-Holzmann , Sarayu Ramakrishna , Ravi Muddashetty , Rachel Steeg , Kevin Bruce , Peter Mackintosh , Andreas Ebneth , Bjørn Holst , Alfredo Cabrera-Socorro

Pharmacological characterization of mutant huntingtin aggregate-directed PET imaging tracer candidates.

Scientific reports

Avec: Frank Herrmann , Manuela Hessmann , Sabine Schaertl , Karola Berg-Rosseburg , Christopher J Brown , Galina Bursow , Anass Chiki , Andreas Ebneth , Miriam Gehrmann , Nicole Hoeschen , Madlen Hotze , Stefanie Jahn , Peter D Johnson , Vinod Khetarpal , Alex Kiselyov , Karsten Kottig , Stefanie Ladewig , Hilal Lashuel , Sven Letschert , Matthew R Mills , Kathrin Petersen , Michael E Prime , Christoph Scheich , Gerhard Schmiedel , John Wityak , Longbin Liu , Celia Dominguez , Ignacio Muñoz-Sanjuán , Jonathan A Bard

Generation of three isogenic, gene-edited iPSC lines carrying the APOE-Christchurch mutation into the three common APOE variants: APOE2Ch, APOE3Ch and APOE4Ch.

Stem cell research

Avec: Mansour Haidar , Benjamin Schmid , Agustín Ruiz , Andreas Ebneth , Alfredo Cabrera-Socorro

Réseau de co-auteurs

Andreas Ebneth 12 collaborations

Alfredo Cabrera-Socorro 7 collaborations

Rachel Steeg 5 collaborations

Benjamin Schmid 5 collaborations

Bjørn Holst 5 collaborations

Christian Clausen 5 collaborations

Julia C Neubauer 2 collaborations

Heiko Zimmermann 2 collaborations

Pei-Yu Shih 2 collaborations

Mohamed Kreir 2 collaborations

Devesh Kumar 2 collaborations

Frederik Seibt 2 collaborations

Benjamin Fischer 2 collaborations

Andrés A Trabanco 2 collaborations

Catherine Verfaillie 2 collaborations

Longbin Liu 2 collaborations

Michael E Prime 2 collaborations

Vinod Khetarpal 2 collaborations

Christopher J Brown 2 collaborations

Peter D Johnson 2 collaborations

Frank Herrmann 2 collaborations

Matthew R Mills 2 collaborations

Sabine Schaertl 2 collaborations

Christoph Scheich 2 collaborations

John Wityak 2 collaborations

Jonathan A Bard 2 collaborations

Celia Dominguez 2 collaborations

Ulla Poulsen 2 collaborations

Ida Jørring 2 collaborations

Ulrike A Mau-Holzmann 2 collaborations

Sabine C Müller 1 collaboration

Francisco Pestana 1 collaboration

Juan Pita-Almenar 1 collaboration

Luke A Miles 1 collaboration

Stefan J Hermans 1 collaboration

Gabriela A N Crespi 1 collaboration

Jonathan H Gooi 1 collaboration

Larissa Doughty 1 collaboration

Tracy L Nero 1 collaboration

Jasmina Markulić 1 collaboration

Berthold Wroblowski 1 collaboration

Daniel Oehlrich 1 collaboration

Marie-Laure Rives 1 collaboration

Ines Royaux 1 collaboration

Nancy C Hancock 1 collaboration

Michael W Parker 1 collaboration

Chee Keong Kwok 1 collaboration

Isabelle Sébastien 1 collaboration

Krithika Hariharan 1 collaboration

Ina Meiser 1 collaboration

Jeanette Wihan 1 collaboration

Saskia Altmaier 1 collaboration

Isabell Karnatz 1 collaboration

Dominic Bauer 1 collaboration

Alexander Feile 1 collaboration

Mikkel Rasmussen 1 collaboration

Mattias Hansson 1 collaboration

Carlos M Martínez-Viturro 1 collaboration

Jordi Royes 1 collaboration

Elena Fernández 1 collaboration

Gary Tresadern 1 collaboration

Juan A Vega 1 collaboration

Alcira Del Cerro 1 collaboration

Francisca Delgado 1 collaboration

Aránzazu García Molina 1 collaboration

Fulgencio Tovar 1 collaboration

Paul Shaffer 1 collaboration

Alexis Bretteville 1 collaboration

Liesbeth Mertens 1 collaboration

Marijke Somers 1 collaboration

Jose M Alonso 1 collaboration

José M Bartolomé-Nebreda 1 collaboration

Lamiaa Bahnassawy 1 collaboration

Peter Reinhardt 1 collaboration

Margot H M Bakker 1 collaboration

Eva Díaz-Guerra 1 collaboration

Carlos Vicario 1 collaboration

Pamela V Martino-Adami 1 collaboration

Michaela Thoenes 1 collaboration

Alfredo Ramirez 1 collaboration

Klaus Fliessbach 1 collaboration

Clara Grezella 1 collaboration

Oliver Brüstle 1 collaboration

Michael Peitz 1 collaboration

Matt R Lee 1 collaboration

Patricia Miranda-Azpiazu 1 collaboration

Xuemei Chen 1 collaboration

Daniel Clark-Frew 1 collaboration

Samuel Coe 1 collaboration

Randall Davis 1 collaboration

Anthony Dickie 1 collaboration

Simone Esposito 1 collaboration

Elise Gadouleau 1 collaboration

Xinjie Gai 1 collaboration

Sebastien Galan 1 collaboration

Samantha Green 1 collaboration

Catherine Greenaway 1 collaboration

Paul Giles 1 collaboration

Christer Halldin 1 collaboration

Sarah Hayes 1 collaboration

Todd Herbst 1 collaboration

Manuela Heßmann 1 collaboration

Zhisheng Jia 1 collaboration

Alexander Kiselyov 1 collaboration

Adrian Kotey 1 collaboration

Thomas Krulle 1 collaboration

John E Mangette 1 collaboration

Richard W Marston 1 collaboration

Sergio Menta 1 collaboration

Edith Monteagudo 1 collaboration

Sangram Nag 1 collaboration

Martina Nibbio 1 collaboration

Laura Orsatti 1 collaboration

Joanne Sproston 1 collaboration

Vladimir Stepanov 1 collaboration

Marie Svedberg 1 collaboration

Akihiro Takano 1 collaboration

Malcolm Taylor 1 collaboration

Wayne Thomas 1 collaboration

Miklós Toth 1 collaboration

Darshan Vaidya 1 collaboration

Katarina Vanräs 1 collaboration

Derek Weddell 1 collaboration

Ian Wigginton 1 collaboration

Ladislav Mrzljak 1 collaboration

Ignacio Munoz-Sanjuan 1 collaboration

Timothy E Allsopp 1 collaboration

M Rasmussen 1 collaboration

Hugh Nuthall 1 collaboration

A Cabrera-Socorro 1 collaboration

Katrien Neyrinck 1 collaboration

Johanna Van Den Daele 1 collaboration

Tim Vervliet 1 collaboration

Jonathan De Smedt 1 collaboration

Keimpe Wierda 1 collaboration

Melissa Nijs 1 collaboration

Tom Vanbokhoven 1 collaboration

Astrid D'hondt 1 collaboration

Mélanie Planque 1 collaboration

Sarah-Maria Fendt 1 collaboration

Juan Pita Almenar 1 collaboration

Vania Broccoli 1 collaboration

Geert Bultynck 1 collaboration

Kennie R Prehn 1 collaboration

Natakarn Nimsanor 1 collaboration

Blanca Irene Aldana Garcia 1 collaboration

Mikkel A Rasmussen 1 collaboration

Sarayu Ramakrishna 1 collaboration

Ravi Muddashetty 1 collaboration

Kevin Bruce 1 collaboration

Peter Mackintosh 1 collaboration

Manuela Hessmann 1 collaboration

Karola Berg-Rosseburg 1 collaboration

Galina Bursow 1 collaboration

Anass Chiki 1 collaboration

Miriam Gehrmann 1 collaboration

Nicole Hoeschen 1 collaboration

Madlen Hotze 1 collaboration

Stefanie Jahn 1 collaboration

Alex Kiselyov 1 collaboration

Karsten Kottig 1 collaboration

Stefanie Ladewig 1 collaboration

Hilal Lashuel 1 collaboration

Sven Letschert 1 collaboration

Kathrin Petersen 1 collaboration

Gerhard Schmiedel 1 collaboration

Ignacio Muñoz-Sanjuán 1 collaboration

Mansour Haidar 1 collaboration

Agustín Ruiz 1 collaboration