Alejandro Benjamin Balazs

Publications (23)

Delivering genes across the blood-brain barrier: LY6A, a novel cellular receptor for AAV-PHP.B capsids.

PloS one

Avec: Qin Huang , Ken Y Chan , Isabelle G Tobey , Yujia Alina Chan , Tim Poterba , Christine L Boutros , Alejandro B Balazs , Richard Daneman , Jonathan M Bloom , Cotton Seed , Benjamin E Deverman

Comprehensive antibody profiling of mRNA vaccination in children.

bioRxiv : the preprint server for biology

Avec: Yannic C Bartsch , Kerri J St Denis , Paulina Kaplonek , Jaewon Kang , Evan C Lam , Madeleine D Burns , Eva J Farkas , Jameson P Davis , Brittany P Boribong , Andrea G Edlow , Alessio Fasano , Wayne Shreffler , Dace Zavadska , Marina Johnson , David Goldblatt , Alejandro B Balazs , Lael M Yonker , Galit Alter

Naive human B cells engage the receptor binding domain of SARS-CoV-2, variants of concern, and related sarbecoviruses.

Science immunology

Avec: Jared Feldman , Julia Bals , Clara G Altomare , Kerri St Denis , Evan C Lam , Blake M Hauser , Larance Ronsard , Maya Sangesland , Thalia Bracamonte Moreno , Vintus Okonkwo , Nathania Hartojo , Alejandro B Balazs , Goran Bajic , Daniel Lingwood , Aaron G Schmidt

COVID-19 neutralizing antibodies predict disease severity and survival.

medRxiv : the preprint server for health sciences

Avec: Wilfredo F Garcia-Beltran , Evan C Lam , Michael G Astudillo , Diane Yang , Tyler E Miller , Jared Feldman , Blake M Hauser , Timothy M Caradonna , Kiera L Clayton , Adam D Nitido , Mandakolathur R Murali , Galit Alter , Richelle C Charles , Anand Dighe , John A Branda , Jochen K Lennerz , Daniel Lingwood , Aaron G Schmidt , A John Iafrate , Alejandro B Balazs

Enhancing durability of CIS43 monoclonal antibody by Fc mutation or AAV delivery for malaria prevention.

JCI insight

Avec: Neville K Kisalu , Lais D Pereira , Keenan Ernste , Yevel Flores-Garcia , Azza H Idris , Mangaiarkarasi Asokan , Marlon Dillon , Scott MacDonald , Wei Shi , Xuejun Chen , Amarendra Pegu , Arne Schön , Fidel Zavala , Alejandro B Balazs , Joseph R Francica , Robert A Seder

mRNA-based COVID-19 vaccine boosters induce neutralizing immunity against SARS-CoV-2 Omicron variant.

Cell

Avec: Wilfredo F Garcia-Beltran , Kerri J St Denis , Angelique Hoelzemer , Evan C Lam , Adam D Nitido , Maegan L Sheehan , Cristhian Berrios , Onosereme Ofoman , Christina C Chang , Blake M Hauser , Jared Feldman , Alex L Roederer , David J Gregory , Mark C Poznansky , Aaron G Schmidt , A John Iafrate , Vivek Naranbhai , Alejandro B Balazs

T cell reactivity to the SARS-CoV-2 Omicron variant is preserved in most but not all individuals.

Cell

Avec: Vivek Naranbhai , Anusha Nathan , Clarety Kaseke , Cristhian Berrios , Ashok Khatri , Shawn Choi , Matthew A Getz , Rhoda Tano-Menka , Onosereme Ofoman , Alton Gayton , Fernando Senjobe , Zezhou Zhao , Kerri J St Denis , Evan C Lam , Mary Carrington , Wilfredo F Garcia-Beltran , Alejandro B Balazs , Bruce D Walker , A John Iafrate , Gaurav D Gaiha

Durability of immunity and clinical protection in nursing home residents following bivalent SARS-CoV-2 vaccination.

medRxiv : the preprint server for health sciences

Avec: Stefan Gravenstein , Frank DeVone , Oladayo A Oyebanji , Yasin Abul , Yi Cao , Philip A Chan , Christopher W Halladay , Kevin W McConeghy , Clare Nugent , Jürgen Bosch , Christopher L King , Brigid M Wilson , Alejandro B Balazs , Elizabeth M White , David H Canaday

Heterologous sarbecovirus receptor binding domains as scaffolds for SARS-CoV-2 receptor binding motif presentation.

bioRxiv : the preprint server for biology

Avec: Blake M Hauser , Maya Sangesland , Evan C Lam , Kerri J St Denis , Maegan L Sheehan , Mya L Vu , Agnes H Cheng , Alejandro B Balazs , Daniel Lingwood , Aaron G Schmidt

AAV-Mediated Expression of Broadly Neutralizing and Vaccine-like Antibodies Targeting the HIV-1 Envelope V2 Region.

Molecular therapy. Methods & clinical development

Avec: Fiona T van den Berg , Nigel A Makoah , Stuart A Ali , Tristan A Scott , Rutendo E Mapengo , Lorraine Z Mutsvunguma , Nonhlanhla N Mkhize , Bronwen E Lambson , Prudence D Kgagudi , Carol Crowther , Salim S Abdool Karim , Alejandro B Balazs , Marc S Weinberg , Abdullah Ely , Patrick B Arbuthnot , Lynn Morris

Rationally designed immunogens enable immune focusing to the SARS-CoV-2 receptor binding motif.

bioRxiv : the preprint server for biology

Avec: Blake M Hauser , Maya Sangesland , Kerri J St Denis , Ian W Windsor , Jared Feldman , Evan C Lam , Ty Kannegieter , Alejandro B Balazs , Daniel Lingwood , Aaron G Schmidt

Multiple SARS-CoV-2 variants escape neutralization by vaccine-induced humoral immunity.

Cell

Avec: Wilfredo F Garcia-Beltran , Evan C Lam , Kerri St Denis , Adam D Nitido , Zeidy H Garcia , Blake M Hauser , Jared Feldman , Maia N Pavlovic , David J Gregory , Mark C Poznansky , Alex Sigal , Aaron G Schmidt , A John Iafrate , Vivek Naranbhai , Alejandro B Balazs

COVID-19-neutralizing antibodies predict disease severity and survival.

Cell

Heterogeneous immunogenicity of SARS-CoV-2 vaccines in cancer patients receiving radiotherapy.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Avec: Cynthia L Bowes , Vivek Naranbhai , Kerri J St Denis , Evan C Lam , Brittany Bertaux , Florence K Keane , Melin J Khandekar , Alejandro B Balazs , John A Iafrate , Justin F Gainor , Henning Willers

mRNA-based COVID-19 vaccine boosters induce neutralizing immunity against SARS-CoV-2 Omicron variant.

medRxiv : the preprint server for health sciences

Avec: Wilfredo F Garcia-Beltran , Kerri J St Denis , Angelique Hoelzemer , Evan C Lam , Adam D Nitido , Maegan L Sheehan , Cristhian Berrios , Onosereme Ofoman , Christina C Chang , Blake M Hauser , Jared Feldman , David J Gregory , Mark C Poznansky , Aaron G Schmidt , A John Iafrate , Vivek Naranbhai , Alejandro B Balazs

Humanized mice reveal a macrophage-enriched gene signature defining human lung tissue protection during SARS-CoV-2 infection.

Cell reports

Avec: Devin J Kenney , Aoife K O'Connell , Jacquelyn Turcinovic , Paige Montanaro , Ryan M Hekman , Tomokazu Tamura , Andrew R Berneshawi , Thomas R Cafiero , Salam Al Abdullatif , Benjamin Blum , Stanley I Goldstein , Brigitte L Heller , Hans P Gertje , Esther Bullitt , Alexander J Trachtenberg , Elizabeth Chavez , Evans Tuekam Nono , Catherine Morrison , Anna E Tseng , Amira Sheikh , Susanna Kurnick , Kyle Grosz , Markus Bosmann , Maria Ericsson , Bertrand R Huber , Mohsan Saeed , Alejandro B Balazs , Kevin P Francis , Alexander Klose , Neal Paragas , Joshua D Campbell , John H Connor , Andrew Emili , Nicholas A Crossland , Alexander Ploss , Florian Douam

Rationally designed immunogens enable immune focusing following SARS-CoV-2 spike imprinting.

Cell reports

Avec: Blake M Hauser , Maya Sangesland , Kerri J St Denis , Evan C Lam , James Brett Case , Ian W Windsor , Jared Feldman , Timothy M Caradonna , Ty Kannegieter , Michael S Diamond , Alejandro B Balazs , Daniel Lingwood , Aaron G Schmidt

Antibody-mediated prevention of vaginal HIV transmission is dictated by IgG subclass in humanized mice.

Science translational medicine

Avec: Jacqueline M Brady , Meredith Phelps , Scott W MacDonald , Evan C Lam , Adam Nitido , Dylan Parsons , Christine L Boutros , Cailin E Deal , Wilfredo F Garcia-Beltran , Serah Tanno , Harini Natarajan , Margaret E Ackerman , Vladimir D Vrbanac , Alejandro B Balazs

Maternally transferred mAbs protect neonatal mice from HSV-induced mortality and morbidity.

The Journal of experimental medicine

Avec: Iara M Backes , Brook K Byrd , Matthew D Slein , Chaya D Patel , Sean A Taylor , Callaghan R Garland , Scott W MacDonald , Alejandro B Balazs , Scott C Davis , Margaret E Ackerman , David A Leib

Cross-reactive SARS-CoV-2 epitope targeted across donors informs immunogen design.

Cell reports. Medicine

Avec: Blake M Hauser , Jared Feldman , Maya Sangesland , Larance Ronsard , Kerri J St Denis , Maegan L Sheehan , Yi Cao , Julie Boucau , Ian W Windsor , Agnes H Cheng , Mya L Vu , Marcella R Cardoso , Ty Kannegieter , Alejandro B Balazs , Daniel Lingwood , Wilfredo F Garcia-Beltran , Aaron G Schmidt

De novo hematopoiesis from the fetal lung.

Blood advances

Avec: Anthony K Yeung , Carlos Villacorta-Martin , Jonathan Lindstrom-Vautrin , Anna C Belkina , Kim Vanuytsel , Todd W Dowrey , Alexandra B Ysasi , Pushpinder Bawa , Feiya Wang , Vladimir Vrbanac , Gustavo Mostoslavsky , Alejandro B Balazs , George J Murphy

QuickFit: A High-Throughput RT-qPCR-Based Assay to Quantify Viral Growth and Fitness In Vitro.

Viruses

Avec: Nicolas M S Galvez , Maegan L Sheehan , Allen Z Lin , Yi Cao , Evan C Lam , Abigail M Jackson , Alejandro B Balazs

Durability of immunity and clinical protection in nursing home residents following bivalent SARS-CoV-2 vaccination.

EBioMedicine

Avec: Stefan Gravenstein , Frank DeVone , Oladayo A Oyebanji , Yasin Abul , Yi Cao , Philip A Chan , Christopher W Halladay , James L Rudolph , Clare Nugent , Jürgen Bosch , Christopher L King , Brigid M Wilson , Alejandro B Balazs , Elizabeth M White , David H Canaday , Kevin W McConeghy

Réseau de co-auteurs

Alejandro B Balazs 23 collaborations

Evan C Lam 14 collaborations

Blake M Hauser 10 collaborations

Aaron G Schmidt 10 collaborations

Kerri J St Denis 9 collaborations

Jared Feldman 9 collaborations

Wilfredo F Garcia-Beltran 8 collaborations

Daniel Lingwood 7 collaborations

A John Iafrate 6 collaborations

Maya Sangesland 5 collaborations

Adam D Nitido 5 collaborations

Maegan L Sheehan 5 collaborations

Vivek Naranbhai 5 collaborations

Yi Cao 4 collaborations

Galit Alter 3 collaborations

Timothy M Caradonna 3 collaborations

Cristhian Berrios 3 collaborations

Onosereme Ofoman 3 collaborations

David J Gregory 3 collaborations

Mark C Poznansky 3 collaborations

Ian W Windsor 3 collaborations

Ty Kannegieter 3 collaborations

Christine L Boutros 2 collaborations

Kerri St Denis 2 collaborations

Larance Ronsard 2 collaborations

Michael G Astudillo 2 collaborations

Diane Yang 2 collaborations

Tyler E Miller 2 collaborations

Kiera L Clayton 2 collaborations

Mandakolathur R Murali 2 collaborations

Richelle C Charles 2 collaborations

Anand Dighe 2 collaborations

John A Branda 2 collaborations

Jochen K Lennerz 2 collaborations

Angelique Hoelzemer 2 collaborations

Christina C Chang 2 collaborations

Stefan Gravenstein 2 collaborations

Frank DeVone 2 collaborations

Oladayo A Oyebanji 2 collaborations

Yasin Abul 2 collaborations

Philip A Chan 2 collaborations

Christopher W Halladay 2 collaborations

Kevin W McConeghy 2 collaborations

Clare Nugent 2 collaborations

Jürgen Bosch 2 collaborations

Christopher L King 2 collaborations

Brigid M Wilson 2 collaborations

Elizabeth M White 2 collaborations

David H Canaday 2 collaborations

Mya L Vu 2 collaborations

Agnes H Cheng 2 collaborations

Scott W MacDonald 2 collaborations

Margaret E Ackerman 2 collaborations

Qin Huang 1 collaboration

Ken Y Chan 1 collaboration

Isabelle G Tobey 1 collaboration

Yujia Alina Chan 1 collaboration

Tim Poterba 1 collaboration

Richard Daneman 1 collaboration

Jonathan M Bloom 1 collaboration

Cotton Seed 1 collaboration

Benjamin E Deverman 1 collaboration

Yannic C Bartsch 1 collaboration

Paulina Kaplonek 1 collaboration

Jaewon Kang 1 collaboration

Madeleine D Burns 1 collaboration

Eva J Farkas 1 collaboration

Jameson P Davis 1 collaboration

Brittany P Boribong 1 collaboration

Andrea G Edlow 1 collaboration

Alessio Fasano 1 collaboration

Wayne Shreffler 1 collaboration

Dace Zavadska 1 collaboration

Marina Johnson 1 collaboration

David Goldblatt 1 collaboration

Lael M Yonker 1 collaboration

Julia Bals 1 collaboration

Clara G Altomare 1 collaboration

Thalia Bracamonte Moreno 1 collaboration

Vintus Okonkwo 1 collaboration

Nathania Hartojo 1 collaboration

Goran Bajic 1 collaboration

Neville K Kisalu 1 collaboration

Lais D Pereira 1 collaboration

Keenan Ernste 1 collaboration

Yevel Flores-Garcia 1 collaboration

Azza H Idris 1 collaboration

Mangaiarkarasi Asokan 1 collaboration

Marlon Dillon 1 collaboration

Scott MacDonald 1 collaboration

Wei Shi 1 collaboration

Xuejun Chen 1 collaboration

Amarendra Pegu 1 collaboration

Arne Schön 1 collaboration

Fidel Zavala 1 collaboration

Joseph R Francica 1 collaboration

Robert A Seder 1 collaboration

Alex L Roederer 1 collaboration

Anusha Nathan 1 collaboration

Clarety Kaseke 1 collaboration

Ashok Khatri 1 collaboration

Shawn Choi 1 collaboration

Matthew A Getz 1 collaboration

Rhoda Tano-Menka 1 collaboration

Alton Gayton 1 collaboration

Fernando Senjobe 1 collaboration

Zezhou Zhao 1 collaboration

Mary Carrington 1 collaboration

Bruce D Walker 1 collaboration

Gaurav D Gaiha 1 collaboration

Fiona T van den Berg 1 collaboration

Nigel A Makoah 1 collaboration

Stuart A Ali 1 collaboration

Tristan A Scott 1 collaboration

Rutendo E Mapengo 1 collaboration

Lorraine Z Mutsvunguma 1 collaboration

Nonhlanhla N Mkhize 1 collaboration

Bronwen E Lambson 1 collaboration

Prudence D Kgagudi 1 collaboration

Carol Crowther 1 collaboration

Salim S Abdool Karim 1 collaboration

Marc S Weinberg 1 collaboration

Abdullah Ely 1 collaboration

Patrick B Arbuthnot 1 collaboration

Lynn Morris 1 collaboration

Zeidy H Garcia 1 collaboration

Maia N Pavlovic 1 collaboration

Alex Sigal 1 collaboration

Cynthia L Bowes 1 collaboration

Brittany Bertaux 1 collaboration

Florence K Keane 1 collaboration

Melin J Khandekar 1 collaboration

John A Iafrate 1 collaboration

Justin F Gainor 1 collaboration

Henning Willers 1 collaboration

Devin J Kenney 1 collaboration

Aoife K O'Connell 1 collaboration

Jacquelyn Turcinovic 1 collaboration

Paige Montanaro 1 collaboration

Ryan M Hekman 1 collaboration

Tomokazu Tamura 1 collaboration

Andrew R Berneshawi 1 collaboration

Thomas R Cafiero 1 collaboration

Salam Al Abdullatif 1 collaboration

Benjamin Blum 1 collaboration

Stanley I Goldstein 1 collaboration

Brigitte L Heller 1 collaboration

Hans P Gertje 1 collaboration

Esther Bullitt 1 collaboration

Alexander J Trachtenberg 1 collaboration

Elizabeth Chavez 1 collaboration

Evans Tuekam Nono 1 collaboration

Catherine Morrison 1 collaboration

Anna E Tseng 1 collaboration

Amira Sheikh 1 collaboration

Susanna Kurnick 1 collaboration

Kyle Grosz 1 collaboration

Markus Bosmann 1 collaboration

Maria Ericsson 1 collaboration

Bertrand R Huber 1 collaboration

Mohsan Saeed 1 collaboration

Kevin P Francis 1 collaboration

Alexander Klose 1 collaboration

Neal Paragas 1 collaboration

Joshua D Campbell 1 collaboration

John H Connor 1 collaboration

Andrew Emili 1 collaboration

Nicholas A Crossland 1 collaboration

Alexander Ploss 1 collaboration

Florian Douam 1 collaboration

James Brett Case 1 collaboration

Michael S Diamond 1 collaboration

Jacqueline M Brady 1 collaboration

Meredith Phelps 1 collaboration

Adam Nitido 1 collaboration

Dylan Parsons 1 collaboration

Cailin E Deal 1 collaboration

Serah Tanno 1 collaboration

Harini Natarajan 1 collaboration

Vladimir D Vrbanac 1 collaboration

Iara M Backes 1 collaboration

Brook K Byrd 1 collaboration

Matthew D Slein 1 collaboration

Chaya D Patel 1 collaboration

Sean A Taylor 1 collaboration

Callaghan R Garland 1 collaboration

Scott C Davis 1 collaboration

David A Leib 1 collaboration

Julie Boucau 1 collaboration

Marcella R Cardoso 1 collaboration

Anthony K Yeung 1 collaboration

Carlos Villacorta-Martin 1 collaboration

Jonathan Lindstrom-Vautrin 1 collaboration

Anna C Belkina 1 collaboration

Kim Vanuytsel 1 collaboration

Todd W Dowrey 1 collaboration

Alexandra B Ysasi 1 collaboration

Pushpinder Bawa 1 collaboration

Feiya Wang 1 collaboration

Vladimir Vrbanac 1 collaboration

Gustavo Mostoslavsky 1 collaboration

George J Murphy 1 collaboration

Nicolas M S Galvez 1 collaboration

Allen Z Lin 1 collaboration

Abigail M Jackson 1 collaboration

James L Rudolph 1 collaboration