Alejandro Bertolet

Affiliations

Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.

Publications (30)

Organic generation of real-world real-time data for clinical evidence in radiation oncology.

International journal of medical informatics

Avec: A Bertolet , A Wals , H Miras , J Macías

Impact of DNA Geometry and Scoring on Monte Carlo Track-Structure Simulations of Initial Radiation-Induced Damage.

Radiation research

Avec: Alejandro Bertolet , José Ramos-Méndez , Aimee McNamara , Dohyeon Yoo , Samuel Ingram , Nicholas Henthorn , John-William Warmenhoven , Bruce Faddegon , Michael Merchant , Stephen J McMahon , Harald Paganetti , Jan Schuemann

Absence of Tissue-Sparing Effects in Partial Proton FLASH Irradiation in Murine Intestine.

Cancers

Avec: Qixian Zhang , Leo E Gerweck , Ethan Cascio , Liqun Gu , Qingyuan Yang , Xinyue Dong , Peigen Huang , Alejandro Bertolet , Konrad Pawel Nesteruk , Wonmo Sung , Aimee L McNamara , Jan Schuemann

Localized

bioRxiv : the preprint server for biology

Avec: J M Quintana , F Jiang , M Kang , V Valladolid Onecha , A Könik , L Qin , V E Rodriguez , H Hu , N Borges , I Khurana , L I Banla , M Le Fur , P Caravan , J Schuemann , A Bertolet , R Weissleder , M A Miller , T S C Ng

Sequencing microsphere selective internal radiotherapy after external beam radiotherapy for hepatocellular carcinoma: proof of concept of a synergistic combination.

The British journal of radiology

Avec: Carlos Huesa-Berral , Jack F Terry , Louis Kunz , Alejandro Bertolet

AMBER: A Modular Model for Tumor Growth, Vasculature and Radiation Response.

Bulletin of mathematical biology

Avec: Louis V Kunz , Jesús J Bosque , Mohammad Nikmaneshi , Ibrahim Chamseddine , Lance L Munn , Jan Schuemann , Harald Paganetti , Alejandro Bertolet

Modelling Dose Effects from Space Irradiations: Combination of High-LET and Low-LET Radiations with a Modified Microdosimetric Kinetic Model.

Life (Basel, Switzerland)

Avec: Alejandro Bertolet , Alejandro Carabe

Implementation of the microdosimetric kinetic model using analytical microdosimetry in a treatment planning system for proton therapy.

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)

Avec: A Bertolet , M A Cortés-Giraldo , A Carabe-Fernandez

Modified Geometry of

Journal of personalized medicine

Avec: Héctor Miras , José Antonio Terrón , Alejandro Bertolet , Antonio Leal

MIDOS: a novel stochastic model towards a treatment planning system for microsphere dosimetry in liver tumors.

European journal of nuclear medicine and molecular imaging

Avec: Carlos Huesa-Berral , Julia D Withrow , Robert J Dawson , Chris Beekman , Wesley E Bolch , Harald Paganetti , Eric Wehrenberg-Klee , Alejandro Bertolet

A framework for in-field and out-of-field patient specific secondary cancer risk estimates from treatment plans using the TOPAS Monte Carlo system.

Physics in medicine and biology

Avec: Isaac Meyer , Nils Peters , Giulia Tamborino , Hoyeon Lee , Alejandro Bertolet , Bruce A Faddegon , Matthew M Mille , Choonsik Lee , Jan Schuemann , Harald Paganetti

Monte Carlo dosimetric analyses on the use of

Physics in medicine and biology

Avec: Mislav Bobić , Carlos Huesa-Berral , Jack F Terry , Louis V Kunz , Jan Schuemann , Darrell R Fisher , Charles Maitz , Alejandro Bertolet

Clinical implications of variable relative biological effectiveness in proton therapy for prostate cancer.

Acta oncologica (Stockholm, Sweden)

Avec: A Bertolet , A Carabe-Fernandez

Segment-averaged LET concept and analytical calculation from microdosimetric quantities in proton radiation therapy.

Medical physics

Avec: A Bertolet , A Baratto-Roldán , M A Cortés-Giraldo , A Carabe-Fernandez

Experimental validation of an analytical microdosimetric model based on Geant4-DNA simulations by using a silicon-based microdosimeter.

Radiation physics and chemistry (Oxford, England : 1993)

Avec: A Bertolet , V Grilj , C Guardiola , A D Harken , M A Cortés-Giraldo , A Baratto-Roldán , A Carabe

An Analytical Microdosimetric Model for Radioimmunotherapeutic Alpha Emitters.

Radiation research

Avec: A Bertolet , M A Cortés-Giraldo , A Carabe-Fernandeza

Proton monoenergetic arc therapy (PMAT) to enhance LETd within the target.

Physics in medicine and biology

Avec: A Bertolet , A Carabe

Radiobiological effectiveness difference of proton arc beams versus conventional proton and photon beams.

Physics in medicine and biology

Avec: Alejandro Carabe , Ilias V Karagounis , Kiet Huynh , Alejandro Bertolet , Noelle François , Michele M Kim , Amit Maity , Eric Abel , Roger Dale

Dose-averaged LET calculation for proton track segments using microdosimetric Monte Carlo simulations.

Medical physics

Avec: A Bertolet , A Baratto-Roldán , S Barbieri , G Baiocco , A Carabe , M A Cortés-Giraldo

Calculation of clinical dose distributions in proton therapy from microdosimetry.

Medical physics

Avec: Alejandro Bertolet , Miguel Antonio Cortés-Giraldo , Kevin Souris , Marie Cohilis , Alejandro Carabe-Fernandez

The relation between microdosimetry and induction of direct damage to DNA by alpha particles.

Physics in medicine and biology

Avec: Alejandro Bertolet , José Ramos-Méndez , Harald Paganetti , Jan Schuemann

Large anatomical changes in head-and-neck cancers - A dosimetric comparison of online and offline adaptive proton therapy.

Clinical and translational radiation oncology

Avec: Mislav Bobić , Arthur Lalonde , Konrad P Nesteruk , Hoyeon Lee , Lena Nenoff , Bram L Gorissen , Alejandro Bertolet , Paul M Busse , Annie W Chan , Brian A Winey , Gregory C Sharp , Joost M Verburg , Antony J Lomax , Harald Paganetti

A systematic analysis of the particle irradiation data ensemble in the key of the microdosimetric kinetic model: Should clonogenic data be used for clinical relative biological effectiveness?

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Avec: Daniel Suárez-García , Miguel Antonio Cortés-Giraldo , Alejandro Bertolet

Gadolinium-Based Nanoparticles Sensitize Ovarian Peritoneal Carcinomatosis to Targeted Radionuclide Therapy.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine

Avec: Clara Diaz Garcia-Prada , Léna Carmes , Salima Atis , Ali Parach , Alejandro Bertolet , Marta Jarlier , Sophie Poty , Daniel Suarez Garcia , Wook-Geun Shin , Stanislas Du Manoir , Jan Schuemann , Olivier Tillement , François Lux , Julie Constanzo , Jean-Pierre Pouget

Decoding Patient Heterogeneity Influencing Radiation-Induced Brain Necrosis.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Ibrahim Chamseddine , Keyur Shah , Hoyeon Lee , Felix Ehret , Jan Schuemann , Alejandro Bertolet , Helen A Shih , Harald Paganetti

Impact of Cardiovascular Disease Risk Factors on Subfoveal Choroidal Thickness by Enhanced-depth Spectral Domain Optical Coherence Tomography.

Optometry and vision science : official publication of the American Academy of Optometry

Avec: Rachel C Druckenbrod , Baharak Asefzadeh , Anne Bertolet

On the concepts of dose-mean lineal energy, unrestricted and restricted dose-averaged LET in proton therapy.

Physics in medicine and biology

Avec: A Bertolet , M A Cortés-Giraldo , A Carabe-Fernandez

A kernel-based algorithm for the spectral fluence of clinical proton beams to calculate dose-averaged LET and other dosimetric quantities of interest.

Medical physics

Avec: A Bertolet , M A Cortés-Giraldo , K Souris , A Carabe

Correlation of LET With MRI Changes in Brain and Potential Implications for Normal Tissue Complication Probability for Patients With Meningioma Treated With Pencil Beam Scanning Proton Therapy.

International journal of radiation oncology, biology, physics

Avec: Alejandro Bertolet , Ramin Abolfath , David J Carlson , Robert A Lustig , Christine Hill-Kayser , Michelle Alonso-Basanta , Alejandro Carabe

The complexity of DNA damage by radiation follows a Gamma distribution: insights from the Microdosimetric Gamma Model.

Frontiers in oncology

Avec: Alejandro Bertolet , Ibrahim Chamseddine , Harald Paganetti , Jan Schuemann

Réseau de co-auteurs

A Bertolet 11 collaborations

Jan Schuemann 9 collaborations

Harald Paganetti 8 collaborations

M A Cortés-Giraldo 7 collaborations

A Carabe-Fernandez 4 collaborations

A Carabe 4 collaborations

Carlos Huesa-Berral 3 collaborations

Ibrahim Chamseddine 3 collaborations

Alejandro Carabe 3 collaborations

Hoyeon Lee 3 collaborations

A Baratto-Roldán 3 collaborations

José Ramos-Méndez 2 collaborations

Jack F Terry 2 collaborations

Louis V Kunz 2 collaborations

Mislav Bobić 2 collaborations

Miguel Antonio Cortés-Giraldo 2 collaborations

A Wals 1 collaboration

H Miras 1 collaboration

J Macías 1 collaboration

Aimee McNamara 1 collaboration

Dohyeon Yoo 1 collaboration

Samuel Ingram 1 collaboration

Nicholas Henthorn 1 collaboration

John-William Warmenhoven 1 collaboration

Bruce Faddegon 1 collaboration

Michael Merchant 1 collaboration

Stephen J McMahon 1 collaboration

Qixian Zhang 1 collaboration

Leo E Gerweck 1 collaboration

Ethan Cascio 1 collaboration

Liqun Gu 1 collaboration

Qingyuan Yang 1 collaboration

Xinyue Dong 1 collaboration

Peigen Huang 1 collaboration

Konrad Pawel Nesteruk 1 collaboration

Wonmo Sung 1 collaboration

Aimee L McNamara 1 collaboration

J M Quintana 1 collaboration

F Jiang 1 collaboration

M Kang 1 collaboration

V Valladolid Onecha 1 collaboration

A Könik 1 collaboration

L Qin 1 collaboration

V E Rodriguez 1 collaboration

H Hu 1 collaboration

N Borges 1 collaboration

I Khurana 1 collaboration

L I Banla 1 collaboration

M Le Fur 1 collaboration

P Caravan 1 collaboration

J Schuemann 1 collaboration

R Weissleder 1 collaboration

M A Miller 1 collaboration

T S C Ng 1 collaboration

Louis Kunz 1 collaboration

Jesús J Bosque 1 collaboration

Mohammad Nikmaneshi 1 collaboration

Lance L Munn 1 collaboration

Héctor Miras 1 collaboration

José Antonio Terrón 1 collaboration

Antonio Leal 1 collaboration

Julia D Withrow 1 collaboration

Robert J Dawson 1 collaboration

Chris Beekman 1 collaboration

Wesley E Bolch 1 collaboration

Eric Wehrenberg-Klee 1 collaboration

Isaac Meyer 1 collaboration

Nils Peters 1 collaboration

Giulia Tamborino 1 collaboration

Bruce A Faddegon 1 collaboration

Matthew M Mille 1 collaboration

Choonsik Lee 1 collaboration

Darrell R Fisher 1 collaboration

Charles Maitz 1 collaboration

V Grilj 1 collaboration

C Guardiola 1 collaboration

A D Harken 1 collaboration

A Carabe-Fernandeza 1 collaboration

Ilias V Karagounis 1 collaboration

Kiet Huynh 1 collaboration

Noelle François 1 collaboration

Michele M Kim 1 collaboration

Amit Maity 1 collaboration

Eric Abel 1 collaboration

Roger Dale 1 collaboration

S Barbieri 1 collaboration

G Baiocco 1 collaboration

Kevin Souris 1 collaboration

Marie Cohilis 1 collaboration

Alejandro Carabe-Fernandez 1 collaboration

Arthur Lalonde 1 collaboration

Konrad P Nesteruk 1 collaboration

Lena Nenoff 1 collaboration

Bram L Gorissen 1 collaboration

Paul M Busse 1 collaboration

Annie W Chan 1 collaboration

Brian A Winey 1 collaboration

Gregory C Sharp 1 collaboration

Joost M Verburg 1 collaboration

Antony J Lomax 1 collaboration

Daniel Suárez-García 1 collaboration

Clara Diaz Garcia-Prada 1 collaboration

Léna Carmes 1 collaboration

Salima Atis 1 collaboration

Ali Parach 1 collaboration

Marta Jarlier 1 collaboration

Sophie Poty 1 collaboration

Daniel Suarez Garcia 1 collaboration

Wook-Geun Shin 1 collaboration

Stanislas Du Manoir 1 collaboration

Olivier Tillement 1 collaboration

François Lux 1 collaboration

Julie Constanzo 1 collaboration

Jean-Pierre Pouget 1 collaboration

Keyur Shah 1 collaboration

Felix Ehret 1 collaboration

Helen A Shih 1 collaboration

Rachel C Druckenbrod 1 collaboration

Baharak Asefzadeh 1 collaboration

Anne Bertolet 1 collaboration

K Souris 1 collaboration

Ramin Abolfath 1 collaboration

David J Carlson 1 collaboration

Robert A Lustig 1 collaboration

Christine Hill-Kayser 1 collaboration

Michelle Alonso-Basanta 1 collaboration