Daniel Durocher

Affiliations

Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada.
Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.

ORCID: 0000-0003-3863-8635

Publications (11)

Assessment of the Accuracy and Reliability of Vascular Surgery Quality Metrics.

Annals of vascular surgery

Avec: Zachary B Fang , Calvin Chao , Dawn Durocher , Julie M Flahive , Jessica P Simons , Andres Schanzer , Francesco A Aiello

Synthetic Lethality in Cancer Therapeutics: The Next Generation.

Cancer discovery

Avec: Jeremy Setton , Michael Zinda , Nadeem Riaz , Daniel Durocher , Michal Zimmermann , Maria Koehler , Jorge S Reis-Filho , Simon N Powell

Lineage-defined leiomyosarcoma subtypes emerge years before diagnosis and determine patient survival.

Nature communications

Avec: Nathaniel D Anderson , Yael Babichev , Fabio Fuligni , Federico Comitani , Mehdi Layeghifard , Rosemarie E Venier , Stefan C Dentro , Anant Maheshwari , Sheena Guram , Claire Wunker , J Drew Thompson , Kyoko E Yuki , Huayun Hou , Matthew Zatzman , Nicholas Light , Marcus Q Bernardini , Jay S Wunder , Irene L Andrulis , Peter Ferguson , Albiruni R Abdul Razak , Carol J Swallow , James J Dowling , Rima S Al-Awar , Richard Marcellus , Marjan Rouzbahman , Moritz Gerstung , Daniel Durocher , Ludmil B Alexandrov , Brendan C Dickson , Rebecca A Gladdy , Adam Shlien

CCNE1 amplification is synthetic lethal with PKMYT1 kinase inhibition.

Nature

Avec: David Gallo , Jordan T F Young , Jimmy Fourtounis , Giovanni Martino , Alejandro Álvarez-Quilón , Cynthia Bernier , Nicole M Duffy , Robert Papp , Anne Roulston , Rino Stocco , Janek Szychowski , Artur Veloso , Hunain Alam , Prasamit S Baruah , Alexanne Bonneau Fortin , Julian Bowlan , Natasha Chaudhary , Jessica Desjardins , Evelyne Dietrich , Sara Fournier , Chloe Fugère-Desjardins , Theo Goullet de Rugy , Marie-Eve Leclaire , Bingcan Liu , Vivek Bhaskaran , Yael Mamane , Henrique Melo , Olivier Nicolas , Akul Singhania , Rachel K Szilard , Ján Tkáč , Shou Yun Yin , Stephen J Morris , Michael Zinda , C Gary Marshall , Daniel Durocher

Functional characterization of a PROTAC directed against BRAF mutant V600E.

Nature chemical biology

Avec: Ganna Posternak , Xiaojing Tang , Pierre Maisonneuve , Ting Jin , Hugo Lavoie , Salima Daou , Stephen Orlicky , Theo Goullet de Rugy , Lauren Caldwell , Kin Chan , Ahmed Aman , Michael Prakesch , Gennady Poda , Pavel Mader , Cassandra Wong , Stefan Maier , Julia Kitaygorodsky , Brett Larsen , Karen Colwill , Zhe Yin , Derek F Ceccarelli , Robert A Batey , Mikko Taipale , Igor Kurinov , David Uehling , Jeff Wrana , Daniel Durocher , Anne-Claude Gingras , Rima Al-Awar , Marc Therrien , Frank Sicheri

Control of homologous recombination by the HROB-MCM8-MCM9 pathway.

Genes & development

Avec: Nicole Hustedt , Yuichiro Saito , Michal Zimmermann , Alejandro Álvarez-Quilón , Dheva Setiaputra , Salomé Adam , Andrea McEwan , Jing Yi Yuan , Michele Olivieri , Yichao Zhao , Masato T Kanemaki , Andrea Jurisicova , Daniel Durocher

Identifying chemogenetic interactions from CRISPR screens with drugZ.

Genome medicine

Avec: Medina Colic , Gang Wang , Michal Zimmermann , Keith Mascall , Megan McLaughlin , Lori Bertolet , W Frank Lenoir , Jason Moffat , Stephane Angers , Daniel Durocher , Traver Hart

RIF1 acts in DNA repair through phosphopeptide recognition of 53BP1.

Molecular cell

Avec: Dheva Setiaputra , Cristina Escribano-Díaz , Julia K Reinert , Pooja Sadana , Dali Zong , Elsa Callen , Chérine Sifri , Jan Seebacher , André Nussenzweig , Nicolas H Thomä , Daniel Durocher

A consensus set of genetic vulnerabilities to ATR inhibition.

Open biology

Avec: Nicole Hustedt , Alejandro Álvarez-Quilón , Andrea McEwan , Jing Yi Yuan , Tiffany Cho , Lisa Koob , Traver Hart , Daniel Durocher

FAM72A antagonizes UNG2 to promote mutagenic repair during antibody maturation.

Nature

Avec: Yuqing Feng , Conglei Li , Jessica A Stewart , Philip Barbulescu , Noé Seija Desivo , Alejandro Álvarez-Quilón , Rossanna C Pezo , Madusha L W Perera , Katherine Chan , Amy Hin Yan Tong , Rukshana Mohamad-Ramshan , Maribel Berru , Diana Nakib , Gavin Li , Gholam Ali Kardar , James R Carlyle , Jason Moffat , Daniel Durocher , Javier M Di Noia , Ashok S Bhagwat , Alberto Martin

A Fast-Track Pathway for Emergency General Surgery at an Academic Medical Center.

The Journal of surgical research

Avec: Amanda Fazzalari , Shruthi Srinivas , Suraj Panjwani , Natalie Pozzi , Ann Friedrich , Reeti Sheoran , Joseph Sabato , Dawn Durocher , Martin Reznek , Francesco Aiello , Demetrius Litwin , Mitchell A Cahan

Réseau de co-auteurs

Alejandro Álvarez-Quilón 4 collaborations

Michal Zimmermann 3 collaborations

Dawn Durocher 2 collaborations

Michael Zinda 2 collaborations

Theo Goullet de Rugy 2 collaborations

Nicole Hustedt 2 collaborations

Dheva Setiaputra 2 collaborations

Andrea McEwan 2 collaborations

Jing Yi Yuan 2 collaborations

Jason Moffat 2 collaborations

Traver Hart 2 collaborations

Zachary B Fang 1 collaboration

Calvin Chao 1 collaboration

Julie M Flahive 1 collaboration

Jessica P Simons 1 collaboration

Andres Schanzer 1 collaboration

Francesco A Aiello 1 collaboration

Jeremy Setton 1 collaboration

Nadeem Riaz 1 collaboration

Maria Koehler 1 collaboration

Jorge S Reis-Filho 1 collaboration

Simon N Powell 1 collaboration

Nathaniel D Anderson 1 collaboration

Yael Babichev 1 collaboration

Fabio Fuligni 1 collaboration

Federico Comitani 1 collaboration

Mehdi Layeghifard 1 collaboration

Rosemarie E Venier 1 collaboration

Stefan C Dentro 1 collaboration

Anant Maheshwari 1 collaboration

Sheena Guram 1 collaboration

Claire Wunker 1 collaboration

J Drew Thompson 1 collaboration

Kyoko E Yuki 1 collaboration

Huayun Hou 1 collaboration

Matthew Zatzman 1 collaboration

Nicholas Light 1 collaboration

Marcus Q Bernardini 1 collaboration

Jay S Wunder 1 collaboration

Irene L Andrulis 1 collaboration

Peter Ferguson 1 collaboration

Albiruni R Abdul Razak 1 collaboration

Carol J Swallow 1 collaboration

James J Dowling 1 collaboration

Rima S Al-Awar 1 collaboration

Richard Marcellus 1 collaboration

Marjan Rouzbahman 1 collaboration

Moritz Gerstung 1 collaboration

Ludmil B Alexandrov 1 collaboration

Brendan C Dickson 1 collaboration

Rebecca A Gladdy 1 collaboration

Adam Shlien 1 collaboration

David Gallo 1 collaboration

Jordan T F Young 1 collaboration

Jimmy Fourtounis 1 collaboration

Giovanni Martino 1 collaboration

Cynthia Bernier 1 collaboration

Nicole M Duffy 1 collaboration

Robert Papp 1 collaboration

Anne Roulston 1 collaboration

Rino Stocco 1 collaboration

Janek Szychowski 1 collaboration

Artur Veloso 1 collaboration

Hunain Alam 1 collaboration

Prasamit S Baruah 1 collaboration

Alexanne Bonneau Fortin 1 collaboration

Julian Bowlan 1 collaboration

Natasha Chaudhary 1 collaboration

Jessica Desjardins 1 collaboration

Evelyne Dietrich 1 collaboration

Sara Fournier 1 collaboration

Chloe Fugère-Desjardins 1 collaboration

Marie-Eve Leclaire 1 collaboration

Bingcan Liu 1 collaboration

Vivek Bhaskaran 1 collaboration

Yael Mamane 1 collaboration

Henrique Melo 1 collaboration

Olivier Nicolas 1 collaboration

Akul Singhania 1 collaboration

Rachel K Szilard 1 collaboration

Ján Tkáč 1 collaboration

Shou Yun Yin 1 collaboration

Stephen J Morris 1 collaboration

C Gary Marshall 1 collaboration

Ganna Posternak 1 collaboration

Xiaojing Tang 1 collaboration

Pierre Maisonneuve 1 collaboration

Ting Jin 1 collaboration

Hugo Lavoie 1 collaboration

Salima Daou 1 collaboration

Stephen Orlicky 1 collaboration

Lauren Caldwell 1 collaboration

Kin Chan 1 collaboration

Ahmed Aman 1 collaboration

Michael Prakesch 1 collaboration

Gennady Poda 1 collaboration

Pavel Mader 1 collaboration

Cassandra Wong 1 collaboration

Stefan Maier 1 collaboration

Julia Kitaygorodsky 1 collaboration

Brett Larsen 1 collaboration

Karen Colwill 1 collaboration

Zhe Yin 1 collaboration

Derek F Ceccarelli 1 collaboration

Robert A Batey 1 collaboration

Mikko Taipale 1 collaboration

Igor Kurinov 1 collaboration

David Uehling 1 collaboration

Jeff Wrana 1 collaboration

Anne-Claude Gingras 1 collaboration

Rima Al-Awar 1 collaboration

Marc Therrien 1 collaboration

Frank Sicheri 1 collaboration

Yuichiro Saito 1 collaboration

Salomé Adam 1 collaboration

Michele Olivieri 1 collaboration

Yichao Zhao 1 collaboration

Masato T Kanemaki 1 collaboration

Andrea Jurisicova 1 collaboration

Medina Colic 1 collaboration

Gang Wang 1 collaboration

Keith Mascall 1 collaboration

Megan McLaughlin 1 collaboration

Lori Bertolet 1 collaboration

W Frank Lenoir 1 collaboration

Stephane Angers 1 collaboration

Cristina Escribano-Díaz 1 collaboration

Julia K Reinert 1 collaboration

Pooja Sadana 1 collaboration

Dali Zong 1 collaboration

Elsa Callen 1 collaboration

Chérine Sifri 1 collaboration

Jan Seebacher 1 collaboration

André Nussenzweig 1 collaboration

Nicolas H Thomä 1 collaboration

Tiffany Cho 1 collaboration

Lisa Koob 1 collaboration

Yuqing Feng 1 collaboration

Conglei Li 1 collaboration

Jessica A Stewart 1 collaboration

Philip Barbulescu 1 collaboration

Noé Seija Desivo 1 collaboration

Rossanna C Pezo 1 collaboration

Madusha L W Perera 1 collaboration

Katherine Chan 1 collaboration

Amy Hin Yan Tong 1 collaboration

Rukshana Mohamad-Ramshan 1 collaboration

Maribel Berru 1 collaboration

Diana Nakib 1 collaboration

Gavin Li 1 collaboration

Gholam Ali Kardar 1 collaboration

James R Carlyle 1 collaboration

Javier M Di Noia 1 collaboration

Ashok S Bhagwat 1 collaboration

Alberto Martin 1 collaboration

Amanda Fazzalari 1 collaboration

Shruthi Srinivas 1 collaboration

Suraj Panjwani 1 collaboration

Natalie Pozzi 1 collaboration

Ann Friedrich 1 collaboration

Reeti Sheoran 1 collaboration

Joseph Sabato 1 collaboration

Martin Reznek 1 collaboration

Francesco Aiello 1 collaboration

Demetrius Litwin 1 collaboration

Mitchell A Cahan 1 collaboration