David Cobrinik

Affiliations

The Vision Center and The Saban Research Institute, Children's Hospital Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles, CA, United States.

Publications (21)

Detection of mitochondrial DNA variants at low level heteroplasmy in pediatric CNS and extra-CNS solid tumors with three different enrichment methods.

Mitochondrion

Avec: Kristiyana Kaneva , Daria Merkurjev , Dejerianne Ostrow , Alex Ryutov , Petr Triska , Kevin Stachelek , David Cobrinik , Jaclyn A Biegel , Xiaowu Gai

Simultaneous identification of clinically relevant

Ophthalmic genetics

Avec: Liya Xu , Lishuang Shen , Ashley Polski , Rishvanth K Prabakar , Rachana Shah , Rima Jubran , Jonathan W Kim , Jacklyn Biegel , Peter Kuhn , David Cobrinik , James Hicks , Xiaowu Gai , Jesse L Berry

Aberrant gene expression yet undiminished retinal ganglion cell genesis in iPSC-derived models of optic nerve hypoplasia.

Ophthalmic genetics

Avec: Jennifer G Aparicio , Hanno Hopp , Narine Harutyunyan , Carly Stewart , David Cobrinik , Mark Borchert

Conservative management of retinoblastoma: Challenging orthodoxy without compromising the state of metastatic grace. "Alive, with good vision and no comorbidity".

Progress in retinal and eye research

Avec: Francis L Munier , Maja Beck-Popovic , Guillermo L Chantada , David Cobrinik , Tero T Kivelä , Dietmar Lohmann , Philippe Maeder , Annette C Moll , Angel Montero Carcaboso , Alexandre Moulin , Paula Schaiquevich , Ciara Bergin , Paul J Dyson , Susan Houghton , Francesco Puccinelli , Yvan Vial , Marie-Claire Gaillard , Christina Stathopoulos

Benign Lobular Inner Nuclear Layer Proliferations of the Retina Associated with Congenital Hypertrophy of the Retinal Pigment Epithelium.

Ophthalmology

Avec: Christian J Sanfilippo , Michael Javaheri , Sheryl Handler , Jesse L Berry , David Cobrinik , Matthew A Deardorff , Miao Sun , Ryan J Schmidt , Andrew J Barkmeier , Aaron Nagiel

Non-synonymous, synonymous, and non-coding nucleotide variants contribute to recurrently altered biological processes during retinoblastoma progression.

Genes, chromosomes & cancer

Avec: Kevin Stachelek , Narine Harutyunyan , Susan Lee , Assaf Beck , Jonathan Kim , Liya Xu , Jesse L Berry , Aaron Nagiel , C Patrick Reynolds , A Linn Murphree , Thomas C Lee , Jennifer G Aparicio , David Cobrinik

Establishing the Clinical Utility of ctDNA Analysis for Diagnosis, Prognosis, and Treatment Monitoring of Retinoblastoma: The Aqueous Humor Liquid Biopsy.

Cancers

Avec: Liya Xu , Mary E Kim , Ashley Polski , Rishvanth K Prabakar , Lishuang Shen , Chen-Ching Peng , Mark W Reid , Patricia Chévez-Barrios , Jonathan W Kim , Rachana Shah , Rima Jubran , Peter Kuhn , David Cobrinik , Jaclyn A Biegel , Xiaowu Gai , James Hicks , Jesse L Berry

Cell-Free DNA Tumor Fraction in the Aqueous Humor Is Associated With Therapeutic Response in Retinoblastoma Patients.

Translational vision science & technology

Avec: Ashley Polski , Liya Xu , Rishvanth K Prabakar , Jonathan W Kim , Rachana Shah , Rima Jubran , Peter Kuhn , David Cobrinik , James Hicks , Jesse L Berry

Characterizing DNA methylation signatures of retinoblastoma using aqueous humor liquid biopsy.

Nature communications

Avec: Hong-Tao Li , Liya Xu , Daniel J Weisenberger , Meng Li , Wanding Zhou , Chen-Ching Peng , Kevin Stachelek , David Cobrinik , Gangning Liang , Jesse L Berry

Single cell transcriptomics reveals early photoreceptor states, cell-specific transcript isoforms, and cancer-predisposing features.

bioRxiv : the preprint server for biology

Avec: Dominic W H Shayler , Kevin Stachelek , Linda Cambier , Sunhye Lee , Jinlun Bai , Mark W Reid , Daniel J Weisenberger , Bhavana Bhat , Jennifer G Aparicio , Yeha Kim , Mitali Singh , Maxwell Bay , Matthew E Thornton , Eamon K Doyle , Zachary Fouladian , Stephan G Erberich , Brendan H Grubbs , Michael A Bonaguidi , Cheryl Mae Craft , Hardeep P Singh , David Cobrinik

Chromosome 6p Amplification in Aqueous Humor Cell-Free DNA Is a Prognostic Biomarker for Retinoblastoma Ocular Survival.

Molecular cancer research : MCR

Avec: Liya Xu , Ashley Polski , Rishvanth K Prabakar , Mark W Reid , Patricia Chevez-Barrios , Rima Jubran , Jonathan W Kim , Peter Kuhn , David Cobrinik , James Hicks , Jesse L Berry

Variability in retinoblastoma genome stability is driven by age and not heritability.

Genes, chromosomes & cancer

Avec: Ashley Polski , Liya Xu , Rishvanth K Prabakar , Xiaowu Gai , Jonathan W Kim , Rachana Shah , Rima Jubran , Peter Kuhn , David Cobrinik , James Hicks , Jesse L Berry

A novel thyroid hormone receptor isoform, TRβ2-46, promotes SKP2 expression and retinoblastoma cell proliferation.

The Journal of biological chemistry

Avec: Zhengke Li , Dong-Lai Qi , Hardeep P Singh , Yue Zou , Binghui Shen , David Cobrinik

Reciprocal Induction of MDM2 and MYCN in Neural and Neuroendocrine Cancers.

Frontiers in oncology

Avec: Hung N Tran , Hardeep P Singh , Wenxuan Guo , Linda Cambier , Luke Riggan , Gregory M Shackleford , Matthew E Thornton , Brendan H Grubbs , Anat Erdreich-Epstein , Dong-Lai Qi , David Cobrinik

Characterization and staging of outer plexiform layer development in human retina and retinal organoids.

Development (Cambridge, England)

Avec: Sumitha Prameela Bharathan , Angela Ferrario , Kayla Stepanian , G Esteban Fernandez , Mark W Reid , Justin S Kim , Chloe Hutchens , Narine Harutyunyan , Carolyn Marks , Matthew E Thornton , Brendan H Grubbs , David Cobrinik , Jennifer G Aparicio , Aaron Nagiel

Extracellular vesicle-associated repetitive element DNAs as candidate osteosarcoma biomarkers.

Scientific reports

Avec: Linda Cambier , Kevin Stachelek , Martin Triska , Rima Jubran , Manyu Huang , Wuyin Li , Jianying Zhang , Jitian Li , David Cobrinik

Improved third-generation lentiviral packaging with pLKO.1C vectors.

BioTechniques

Avec: Sunhye Lee , David Cobrinik

Comprehensive Somatic Copy Number Analysis Using Aqueous Humor Liquid Biopsy for Retinoblastoma.

Cancers

Avec: Mary E Kim , Ashley Polski , Liya Xu , Rishvanth K Prabakar , Chen-Ching Peng , Mark W Reid , Rachana Shah , Peter Kuhn , David Cobrinik , James Hicks , Jesse L Berry

An immature, dedifferentiated, and lineage-deconstrained cone precursor origin of N-Myc-initiated retinoblastoma.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Hardeep P Singh , Dominic W H Shayler , G Esteban Fernandez , Matthew E Thornton , Cheryl Mae Craft , Brendan H Grubbs , David Cobrinik

Episodic live imaging of cone photoreceptor maturation in GNAT2-EGFP retinal organoids.

bioRxiv : the preprint server for biology

Avec: Jinlun Bai , David S Koos , Kayla Stepanian , Zachary Fouladian , Dominic W H Shayler , Jennifer G Aparicio , Scott E Fraser , Rex A Moats , David Cobrinik

Episodic live imaging of cone photoreceptor maturation in GNAT2-EGFP retinal organoids.

Disease models & mechanisms

Avec: Jinlun Bai , David S Koos , Kayla Stepanian , Zachary Fouladian , Dominic W H Shayler , Jennifer G Aparicio , Scott E Fraser , Rex A Moats , David Cobrinik

Réseau de co-auteurs

Jesse L Berry 9 collaborations

Liya Xu 8 collaborations

Ashley Polski 6 collaborations

Rishvanth K Prabakar 6 collaborations

Rima Jubran 6 collaborations

Peter Kuhn 6 collaborations

James Hicks 6 collaborations

Jennifer G Aparicio 6 collaborations

Kevin Stachelek 5 collaborations

Rachana Shah 5 collaborations

Jonathan W Kim 5 collaborations

Mark W Reid 5 collaborations

Xiaowu Gai 4 collaborations

Dominic W H Shayler 4 collaborations

Matthew E Thornton 4 collaborations

Brendan H Grubbs 4 collaborations

Hardeep P Singh 4 collaborations

Narine Harutyunyan 3 collaborations

Aaron Nagiel 3 collaborations

Chen-Ching Peng 3 collaborations

Linda Cambier 3 collaborations

Jinlun Bai 3 collaborations

Zachary Fouladian 3 collaborations

Kayla Stepanian 3 collaborations

Jaclyn A Biegel 2 collaborations

Lishuang Shen 2 collaborations

Mary E Kim 2 collaborations

Daniel J Weisenberger 2 collaborations

Sunhye Lee 2 collaborations

Cheryl Mae Craft 2 collaborations

Dong-Lai Qi 2 collaborations

G Esteban Fernandez 2 collaborations

David S Koos 2 collaborations

Scott E Fraser 2 collaborations

Rex A Moats 2 collaborations

Kristiyana Kaneva 1 collaboration

Daria Merkurjev 1 collaboration

Dejerianne Ostrow 1 collaboration

Alex Ryutov 1 collaboration

Petr Triska 1 collaboration

Jacklyn Biegel 1 collaboration

Hanno Hopp 1 collaboration

Carly Stewart 1 collaboration

Mark Borchert 1 collaboration

Francis L Munier 1 collaboration

Maja Beck-Popovic 1 collaboration

Guillermo L Chantada 1 collaboration

Tero T Kivelä 1 collaboration

Dietmar Lohmann 1 collaboration

Philippe Maeder 1 collaboration

Annette C Moll 1 collaboration

Angel Montero Carcaboso 1 collaboration

Alexandre Moulin 1 collaboration

Paula Schaiquevich 1 collaboration

Ciara Bergin 1 collaboration

Paul J Dyson 1 collaboration

Susan Houghton 1 collaboration

Francesco Puccinelli 1 collaboration

Yvan Vial 1 collaboration

Marie-Claire Gaillard 1 collaboration

Christina Stathopoulos 1 collaboration

Christian J Sanfilippo 1 collaboration

Michael Javaheri 1 collaboration

Sheryl Handler 1 collaboration

Matthew A Deardorff 1 collaboration

Miao Sun 1 collaboration

Ryan J Schmidt 1 collaboration

Andrew J Barkmeier 1 collaboration

Susan Lee 1 collaboration

Assaf Beck 1 collaboration

Jonathan Kim 1 collaboration

C Patrick Reynolds 1 collaboration

A Linn Murphree 1 collaboration

Thomas C Lee 1 collaboration

Patricia Chévez-Barrios 1 collaboration

Hong-Tao Li 1 collaboration

Meng Li 1 collaboration

Wanding Zhou 1 collaboration

Gangning Liang 1 collaboration

Bhavana Bhat 1 collaboration

Yeha Kim 1 collaboration

Mitali Singh 1 collaboration

Maxwell Bay 1 collaboration

Eamon K Doyle 1 collaboration

Stephan G Erberich 1 collaboration

Michael A Bonaguidi 1 collaboration

Patricia Chevez-Barrios 1 collaboration

Zhengke Li 1 collaboration

Yue Zou 1 collaboration

Binghui Shen 1 collaboration

Hung N Tran 1 collaboration

Wenxuan Guo 1 collaboration

Luke Riggan 1 collaboration

Gregory M Shackleford 1 collaboration

Anat Erdreich-Epstein 1 collaboration

Sumitha Prameela Bharathan 1 collaboration

Angela Ferrario 1 collaboration

Justin S Kim 1 collaboration

Chloe Hutchens 1 collaboration

Carolyn Marks 1 collaboration

Martin Triska 1 collaboration

Manyu Huang 1 collaboration

Wuyin Li 1 collaboration

Jianying Zhang 1 collaboration

Jitian Li 1 collaboration