Gerald F Späth

Affiliations

Institut Pasteur and Institut National de Santé et Recherche Médicale INSERM U1201, Unité de Parasitologie Moléculaire et Signalisation, Paris, France. Electronic address: gerald.spaeth@pasteur.fr.

Publications (14)

SILAC-based quantitative proteomics reveals pleiotropic, phenotypic modulation in primary murine macrophages infected with the protozoan pathogen Leishmania donovani.

Journal of proteomics

Avec: Despina Smirlis , Florent Dingli , Pascale Pescher , Eric Prina , Damarys Loew , Najma Rachidi , Gerald F Späth

Trans-Atlantic Spill Over: Deconstructing the Ecological Adaptation of

Genes

Avec: Mariana C Boité , Gerald F Späth , Giovanni Bussotti , Renato Porrozzi , Fernanda N Morgado , Martin Llewellyn , Philipp Schwabl , Elisa Cupolillo

Leishmania donovani 90 kD Heat Shock Protein - Impact of Phosphosites on Parasite Fitness, Infectivity and Casein Kinase Affinity.

Scientific reports

Avec: Antje Hombach-Barrigah , Katharina Bartsch , Despina Smirlis , Heidi Rosenqvist , Andrea MacDonald , Florent Dingli , Damarys Loew , Gerald F Späth , Najma Rachidi , Martin Wiese , Joachim Clos

Trifloxystrobin blocks the growth of Theileria parasites and is a promising drug to treat Buparvaquone resistance.

Communications biology

Avec: Marie Villares , Nelly Lourenço , Jeremy Berthelet , Suzanne Lamotte , Leslie Regad , Souhila Medjkane , Eric Prina , Fernando Rodrigues-Lima , Gerald F Späth , Jonathan B Weitzman

Dangerous Duplicity: The Dual Functions of Casein Kinase 1 in Parasite Biology and Host Subversion.

Frontiers in cellular and infection microbiology

Avec: Najma Rachidi , Uwe Knippschild , Gerald F Späth

Drug Discovery for Kinetoplastid Diseases: Future Directions.

ACS infectious diseases

Avec: Srinivasa P S Rao , Michael P Barrett , Glenn Dranoff , Christopher J Faraday , Claudio R Gimpelewicz , Asrat Hailu , Catherine L Jones , John M Kelly , Janis K Lazdins-Helds , Pascal Mäser , Jose Mengel , Jeremy C Mottram , Charles E Mowbray , David L Sacks , Phillip Scott , Gerald F Späth , Rick L Tarleton , Jonathan M Spector , Thierry T Diagana

Leishmania dual-specificity tyrosine-regulated kinase 1 (DYRK1) is required for sustaining Leishmania stationary phase phenotype.

Molecular microbiology

Avec: Vinícius Pinto Costa Rocha , Mariko Dacher , Simon Alan Young , Foteini Kolokousi , Antonia Efstathiou , Gerald Frank Späth , Milena Botelho Pereira Soares , Despina Smirlis

Nitric oxide controls proliferation of Leishmania major by inhibiting the recruitment of permissive host cells.

Immunity

Avec: Pauline Formaglio , Mohamad Alabdullah , Anastasios Siokis , Juliane Handschuh , Ina Sauerland , Yan Fu , Anna Krone , Patricia Gintschel , Juliane Stettin , Sandrina Heyde , Juliane Mohr , Lars Philipsen , Anja Schröder , Philippe A Robert , Gang Zhao , Sahamoddin Khailaie , Anne Dudeck , Jessica Bertrand , Gerald F Späth , Sascha Kahlfuß , Philippe Bousso , Burkhart Schraven , Jochen Huehn , Sebastian Binder , Michael Meyer-Hermann , Andreas J Müller

Infectivity and Drug Susceptibility Profiling of Different

Pathogens (Basel, Switzerland)

Avec: Kyung-Hwa Baek , Laura Piel , Thibault Rosazza , Eric Prina , Gerald F Späth , Joo Hwan No

Author Correction: Discovery of novel hit compounds with broad activity against visceral and cutaneous Leishmania species by comparative phenotypic screening.

Scientific reports

Avec: S Lamotte , N Aulner , G F Späth , E Prina

Identification of the Host Substratome of

Frontiers in cell and developmental biology

Avec: Despina Smirlis , Florent Dingli , Valentin Sabatet , Aileen Roth , Uwe Knippschild , Damarys Loew , Gerald F Späth , Najma Rachidi

In vitro identification of imidazo[1,2-a]pyrazine-based antileishmanial agents and evaluation of L. major casein kinase 1 inhibition.

European journal of medicinal chemistry

Avec: Marc-Antoine Bazin , Sandrine Cojean , Fabrice Pagniez , Guillaume Bernadat , Christian Cavé , Isabelle Ourliac-Garnier , Marie-Renée Nourrisson , Cathy Morgado , Carine Picot , Olivier Leclercq , Blandine Baratte , Thomas Robert , Gérald F Späth , Najma Rachidi , Stéphane Bach , Philippe M Loiseau , Patrice Le Pape , Pascal Marchand

Experimental evolution links post-transcriptional regulation to Leishmania fitness gain.

PLoS pathogens

Avec: Laura Piel , K Shanmugha Rajan , Giovanni Bussotti , Hugo Varet , Rachel Legendre , Caroline Proux , Thibaut Douché , Quentin Giai-Gianetto , Thibault Chaze , Thomas Cokelaer , Barbora Vojtkova , Nadav Gordon-Bar , Tirza Doniger , Smadar Cohen-Chalamish , Praveenkumar Rengaraj , Céline Besse , Anne Boland , Jovana Sadlova , Jean-François Deleuze , Mariette Matondo , Ron Unger , Petr Volf , Shulamit Michaeli , Pascale Pescher , Gerald F Späth

Effects of Structurally Different HDAC Inhibitors against

ACS infectious diseases

Avec: Elisabetta Di Bello , Beatrice Noce , Rossella Fioravanti , Clemens Zwergel , Sergio Valente , Dante Rotili , Giulia Fianco , Daniela Trisciuoglio , Marina M Mourão , Policarpo Sales , Suzanne Lamotte , Eric Prina , Gerald F Späth , Cécile Häberli , Jennifer Keiser , Antonello Mai

Réseau de co-auteurs

Najma Rachidi 5 collaborations

Despina Smirlis 4 collaborations

Eric Prina 4 collaborations

Florent Dingli 3 collaborations

Damarys Loew 3 collaborations

Pascale Pescher 2 collaborations

Giovanni Bussotti 2 collaborations

Suzanne Lamotte 2 collaborations

Uwe Knippschild 2 collaborations

Laura Piel 2 collaborations

Mariana C Boité 1 collaboration

Renato Porrozzi 1 collaboration

Fernanda N Morgado 1 collaboration

Martin Llewellyn 1 collaboration

Philipp Schwabl 1 collaboration

Elisa Cupolillo 1 collaboration

Antje Hombach-Barrigah 1 collaboration

Katharina Bartsch 1 collaboration

Heidi Rosenqvist 1 collaboration

Andrea MacDonald 1 collaboration

Martin Wiese 1 collaboration

Joachim Clos 1 collaboration

Marie Villares 1 collaboration

Nelly Lourenço 1 collaboration

Jeremy Berthelet 1 collaboration

Leslie Regad 1 collaboration

Souhila Medjkane 1 collaboration

Fernando Rodrigues-Lima 1 collaboration

Jonathan B Weitzman 1 collaboration

Srinivasa P S Rao 1 collaboration

Michael P Barrett 1 collaboration

Glenn Dranoff 1 collaboration

Christopher J Faraday 1 collaboration

Claudio R Gimpelewicz 1 collaboration

Asrat Hailu 1 collaboration

Catherine L Jones 1 collaboration

John M Kelly 1 collaboration

Janis K Lazdins-Helds 1 collaboration

Pascal Mäser 1 collaboration

Jose Mengel 1 collaboration

Jeremy C Mottram 1 collaboration

Charles E Mowbray 1 collaboration

David L Sacks 1 collaboration

Phillip Scott 1 collaboration

Rick L Tarleton 1 collaboration

Jonathan M Spector 1 collaboration

Thierry T Diagana 1 collaboration

Vinícius Pinto Costa Rocha 1 collaboration

Mariko Dacher 1 collaboration

Simon Alan Young 1 collaboration

Foteini Kolokousi 1 collaboration

Antonia Efstathiou 1 collaboration

Gerald Frank Späth 1 collaboration

Milena Botelho Pereira Soares 1 collaboration

Pauline Formaglio 1 collaboration

Mohamad Alabdullah 1 collaboration

Anastasios Siokis 1 collaboration

Juliane Handschuh 1 collaboration

Ina Sauerland 1 collaboration

Yan Fu 1 collaboration

Anna Krone 1 collaboration

Patricia Gintschel 1 collaboration

Juliane Stettin 1 collaboration

Sandrina Heyde 1 collaboration

Juliane Mohr 1 collaboration

Lars Philipsen 1 collaboration

Anja Schröder 1 collaboration

Philippe A Robert 1 collaboration

Gang Zhao 1 collaboration

Sahamoddin Khailaie 1 collaboration

Anne Dudeck 1 collaboration

Jessica Bertrand 1 collaboration

Sascha Kahlfuß 1 collaboration

Philippe Bousso 1 collaboration

Burkhart Schraven 1 collaboration

Jochen Huehn 1 collaboration

Sebastian Binder 1 collaboration

Michael Meyer-Hermann 1 collaboration

Andreas J Müller 1 collaboration

Kyung-Hwa Baek 1 collaboration

Thibault Rosazza 1 collaboration

Joo Hwan No 1 collaboration

S Lamotte 1 collaboration

N Aulner 1 collaboration

G F Späth 1 collaboration

E Prina 1 collaboration

Valentin Sabatet 1 collaboration

Aileen Roth 1 collaboration

Marc-Antoine Bazin 1 collaboration

Sandrine Cojean 1 collaboration

Fabrice Pagniez 1 collaboration

Guillaume Bernadat 1 collaboration

Christian Cavé 1 collaboration

Isabelle Ourliac-Garnier 1 collaboration

Marie-Renée Nourrisson 1 collaboration

Cathy Morgado 1 collaboration

Carine Picot 1 collaboration

Olivier Leclercq 1 collaboration

Blandine Baratte 1 collaboration

Thomas Robert 1 collaboration

Gérald F Späth 1 collaboration

Stéphane Bach 1 collaboration

Philippe M Loiseau 1 collaboration

Patrice Le Pape 1 collaboration

Pascal Marchand 1 collaboration

K Shanmugha Rajan 1 collaboration

Hugo Varet 1 collaboration

Rachel Legendre 1 collaboration

Caroline Proux 1 collaboration

Thibaut Douché 1 collaboration

Quentin Giai-Gianetto 1 collaboration

Thibault Chaze 1 collaboration

Thomas Cokelaer 1 collaboration

Barbora Vojtkova 1 collaboration

Nadav Gordon-Bar 1 collaboration

Tirza Doniger 1 collaboration

Smadar Cohen-Chalamish 1 collaboration

Praveenkumar Rengaraj 1 collaboration

Céline Besse 1 collaboration

Anne Boland 1 collaboration

Jovana Sadlova 1 collaboration

Jean-François Deleuze 1 collaboration

Mariette Matondo 1 collaboration

Ron Unger 1 collaboration

Petr Volf 1 collaboration

Shulamit Michaeli 1 collaboration

Elisabetta Di Bello 1 collaboration

Beatrice Noce 1 collaboration

Rossella Fioravanti 1 collaboration

Clemens Zwergel 1 collaboration

Sergio Valente 1 collaboration

Dante Rotili 1 collaboration

Giulia Fianco 1 collaboration

Daniela Trisciuoglio 1 collaboration

Marina M Mourão 1 collaboration

Policarpo Sales 1 collaboration

Cécile Häberli 1 collaboration

Jennifer Keiser 1 collaboration

Antonello Mai 1 collaboration