Jan Beumer

Publications (20)

Snake Venom Gland Organoids.

Cell

Avec: Yorick Post , Jens Puschhof , Joep Beumer , Harald M Kerkkamp , Merijn A G de Bakker , Julien Slagboom , Buys de Barbanson , Nienke R Wevers , Xandor M Spijkers , Thomas Olivier , Taline D Kazandjian , Stuart Ainsworth , Carmen Lopez Iglesias , Willine J van de Wetering , Maria C Heinz , Ravian L van Ineveld , Regina G D M van Kleef , Harry Begthel , Jeroen Korving , Yotam E Bar-Ephraim , Walter Getreuer , Anne C Rios , Remco H S Westerink , Hugo J G Snippert , Alexander van Oudenaarden , Peter J Peters , Freek J Vonk , Jeroen Kool , Michael K Richardson , Nicholas R Casewell , Hans Clevers

An implant-retained auricular prosthesis complicated by a modified temporal bone resection.

The Journal of prosthetic dentistry

Avec: Paul Canallatos , Jay Jayanetti , John Beumer

Hallmarks of stemness in mammalian tissues.

Cell stem cell

Avec: Joep Beumer , Hans Clevers

Rapid tissue prototyping with micro-organospheres.

Stem cell reports

Avec: Zhaohui Wang , Matteo Boretto , Rosemary Millen , Naveen Natesh , Elena S Reckzeh , Carolyn Hsu , Marcos Negrete , Haipei Yao , William Quayle , Brook E Heaton , Alfred T Harding , Shree Bose , Else Driehuis , Joep Beumer , Grecia O Rivera , Ravian L van Ineveld , Donald Gex , Jessica DeVilla , Daisong Wang , Jens Puschhof , Maarten H Geurts , Athena Yeung , Cait Hamele , Amber Smith , Eric Bankaitis , Kun Xiang , Shengli Ding , Daniel Nelson , Daniel Delubac , Anne Rios , Ralph Abi-Hachem , David Jang , Bradley J Goldstein , Carolyn Glass , Nicholas S Heaton , David Hsu , Hans Clevers , Xiling Shen

Sequencing metabolically labeled transcripts in single cells reveals mRNA turnover strategies.

Science (New York, N.Y.)

Avec: Nico Battich , Joep Beumer , Buys de Barbanson , Lenno Krenning , Chloé S Baron , Marvin E Tanenbaum , Hans Clevers , Alexander van Oudenaarden

The Role of Biofilms and Material Surface Characteristics in Microbial Adhesion to Maxillary Obturator Materials: A Literature Review.

The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association

Avec: Karl M Lyons , Richard D Cannon , John Beumer , Mahmoud M Bakr , Robert M Love

High-Resolution mRNA and Secretome Atlas of Human Enteroendocrine Cells.

Cell

Avec: Joep Beumer , Jens Puschhof , Julia Bauzá-Martinez , Adriana Martínez-Silgado , Rasa Elmentaite , Kylie R James , Alexander Ross , Delilah Hendriks , Benedetta Artegiani , Georg A Busslinger , Bas Ponsioen , Amanda Andersson-Rolf , Aurelia Saftien , Charelle Boot , Kai Kretzschmar , Maarten H Geurts , Yotam E Bar-Ephraim , Cayetano Pleguezuelos-Manzano , Yorick Post , Harry Begthel , Franka van der Linden , Carmen Lopez-Iglesias , Willine J van de Wetering , Reinier van der Linden , Peter J Peters , Albert J R Heck , Joachim Goedhart , Hugo Snippert , Matthias Zilbauer , Sarah A Teichmann , Wei Wu , Hans Clevers

Mutational signature in colorectal cancer caused by genotoxic pks

Nature

Avec: Cayetano Pleguezuelos-Manzano , Jens Puschhof , Axel Rosendahl Huber , Arne van Hoeck , Henry M Wood , Jason Nomburg , Carino Gurjao , Freek Manders , Guillaume Dalmasso , Paul B Stege , Fernanda L Paganelli , Maarten H Geurts , Joep Beumer , Tomohiro Mizutani , Yi Miao , Reinier van der Linden , Stefan van der Elst , Auteur inconnu , K Christopher Garcia , Janetta Top , Rob J L Willems , Marios Giannakis , Richard Bonnet , Phil Quirke , Matthew Meyerson , Edwin Cuppen , Ruben van Boxtel , Hans Clevers

Druggable growth dependencies and tumor evolution analysis in patient-derived organoids of neuroendocrine neoplasms from multiple body sites.

Cancer cell

Avec: Talya L Dayton , Nicolas Alcala , Laura Moonen , Lisanne den Hartigh , Veerle Geurts , Lise Mangiante , Lisa Lap , Antonella F M Dost , Joep Beumer , Sonja Levy , Rachel S van Leeuwaarde , Wenzel M Hackeng , Kris Samsom , Catherine Voegele , Alexandra Sexton-Oates , Harry Begthel , Jeroen Korving , Lisa Hillen , Lodewijk A A Brosens , Sylvie Lantuejoul , Sridevi Jaksani , Niels F M Kok , Koen J Hartemink , Houke M Klomp , Inne H M Borel Rinkes , Anne-Marie Dingemans , Gerlof D Valk , Menno R Vriens , Wieneke Buikhuisen , José van den Berg , Margot Tesselaar , Jules Derks , Ernst Jan Speel , Matthieu Foll , Lynnette Fernández-Cuesta , Hans Clevers

Tubuloid differentiation to model the human distal nephron and collecting duct in health and disease.

Cell reports

Avec: Fjodor A Yousef Yengej , Carla Pou Casellas , Carola M E Ammerlaan , Charlotte J A Olde Hanhof , Emre Dilmen , Joep Beumer , Harry Begthel , Elise M G Meeder , Joost G Hoenderop , Maarten B Rookmaaker , Marianne C Verhaar , Hans Clevers

Establishment and Culture of Human Intestinal Organoids Derived from Adult Stem Cells.

Current protocols in immunology

Avec: Cayetano Pleguezuelos-Manzano , Jens Puschhof , Stieneke van den Brink , Veerle Geurts , Joep Beumer , Hans Clevers

Integration of metabolomics, genomics, and immune phenotypes reveals the causal roles of metabolites in disease.

Genome biology

Avec: Xiaojing Chu , Martin Jaeger , Joep Beumer , Olivier B Bakker , Raul Aguirre-Gamboa , Marije Oosting , Sanne P Smeekens , Simone Moorlag , Vera P Mourits , Valerie A C M Koeken , Charlotte de Bree , Trees Jansen , Ian T Mathews , Khoi Dao , Mahan Najhawan , Jeramie D Watrous , Irma Joosten , Sonia Sharma , Hans J P M Koenen , Sebo Withoff , Iris H Jonkers , Romana T Netea-Maier , Ramnik J Xavier , Lude Franke , Cheng-Jian Xu , Leo A B Joosten , Serena Sanna , Mohit Jain , Vinod Kumar , Hans Clevers , Cisca Wijmenga , Mihai G Netea , Yang Li

Intestinal organoid cocultures with microbes.

Nature protocols

Avec: Jens Puschhof , Cayetano Pleguezuelos-Manzano , Adriana Martinez-Silgado , Ninouk Akkerman , Aurelia Saftien , Charelle Boot , Amy de Waal , Joep Beumer , Devanjali Dutta , Inha Heo , Hans Clevers

Mapping prohormone processing by proteases in human enteroendocrine cells using genetically engineered organoid models.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Joep Beumer , Julia Bauzá-Martinez , Tim S Veth , Veerle Geurts , Charelle Boot , Hannah Gilliam-Vigh , Steen S Poulsen , Filip K Knop , Wei Wu , Hans Clevers

SARS-CoV-2 Omicron entry is type II transmembrane serine protease-mediated in human airway and intestinal organoid models.

Journal of virology

Avec: Anna Z Mykytyn , Tim I Breugem , Maarten H Geurts , Joep Beumer , Debby Schipper , Romy van Acker , Petra B van den Doel , Martin E van Royen , Jingshu Zhang , Hans Clevers , Bart L Haagmans , Mart M Lamers

Analysis of off-tumour toxicities of T-cell-engaging bispecific antibodies via donor-matched intestinal organoids and tumouroids.

Nature biomedical engineering

Avec: Marius F Harter , Timothy Recaldin , Regine Gerard , Blandine Avignon , Yannik Bollen , Cinzia Esposito , Karolina Guja-Jarosz , Kristina Kromer , Adrian Filip , Julien Aubert , Anneliese Schneider , Marina Bacac , Michael Bscheider , Nadine Stokar-Regenscheit , Salvatore Piscuoglio , Joep Beumer , Nikolche Gjorevski

A comprehensive transcriptome characterization of individual nuclear receptor pathways in the human small intestine.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Sam Willemsen , Fjodor A Yousef Yengej , Jens Puschhof , Maarten B Rookmaaker , Marianne C Verhaar , Johan van Es , Joep Beumer , Hans Clevers

Enteroendocrine Dynamics - New Tools Reveal Hormonal Plasticity in the Gut.

Endocrine reviews

Avec: Joep Beumer , Helmuth Gehart , Hans Clevers

Fast and efficient generation of knock-in human organoids using homology-independent CRISPR-Cas9 precision genome editing.

Nature cell biology

Avec: Benedetta Artegiani , Delilah Hendriks , Joep Beumer , Rutger Kok , Xuan Zheng , Indi Joore , Susana Chuva de Sousa Lopes , Jeroen van Zon , Sander Tans , Hans Clevers

SARS-CoV-2 productively infects human gut enterocytes.

Science (New York, N.Y.)

Avec: Mart M Lamers , Joep Beumer , Jelte van der Vaart , Kèvin Knoops , Jens Puschhof , Tim I Breugem , Raimond B G Ravelli , J Paul van Schayck , Anna Z Mykytyn , Hans Q Duimel , Elly van Donselaar , Samra Riesebosch , Helma J H Kuijpers , Debby Schipper , Willine J van de Wetering , Miranda de Graaf , Marion Koopmans , Edwin Cuppen , Peter J Peters , Bart L Haagmans , Hans Clevers

Réseau de co-auteurs

Joep Beumer 18 collaborations

Hans Clevers 17 collaborations

Jens Puschhof 8 collaborations

Harry Begthel 4 collaborations

Maarten H Geurts 4 collaborations

Cayetano Pleguezuelos-Manzano 4 collaborations

Willine J van de Wetering 3 collaborations

Peter J Peters 3 collaborations

Charelle Boot 3 collaborations

Veerle Geurts 3 collaborations

Yorick Post 2 collaborations

Buys de Barbanson 2 collaborations

Ravian L van Ineveld 2 collaborations

Jeroen Korving 2 collaborations

Yotam E Bar-Ephraim 2 collaborations

Alexander van Oudenaarden 2 collaborations

John Beumer 2 collaborations

Julia Bauzá-Martinez 2 collaborations

Delilah Hendriks 2 collaborations

Benedetta Artegiani 2 collaborations

Aurelia Saftien 2 collaborations

Reinier van der Linden 2 collaborations

Wei Wu 2 collaborations

Edwin Cuppen 2 collaborations

Fjodor A Yousef Yengej 2 collaborations

Maarten B Rookmaaker 2 collaborations

Marianne C Verhaar 2 collaborations

Anna Z Mykytyn 2 collaborations

Tim I Breugem 2 collaborations

Debby Schipper 2 collaborations

Bart L Haagmans 2 collaborations

Mart M Lamers 2 collaborations

Harald M Kerkkamp 1 collaboration

Merijn A G de Bakker 1 collaboration

Julien Slagboom 1 collaboration

Nienke R Wevers 1 collaboration

Xandor M Spijkers 1 collaboration

Thomas Olivier 1 collaboration

Taline D Kazandjian 1 collaboration

Stuart Ainsworth 1 collaboration

Carmen Lopez Iglesias 1 collaboration

Maria C Heinz 1 collaboration

Regina G D M van Kleef 1 collaboration

Walter Getreuer 1 collaboration

Anne C Rios 1 collaboration

Remco H S Westerink 1 collaboration

Hugo J G Snippert 1 collaboration

Freek J Vonk 1 collaboration

Jeroen Kool 1 collaboration

Michael K Richardson 1 collaboration

Nicholas R Casewell 1 collaboration

Paul Canallatos 1 collaboration

Jay Jayanetti 1 collaboration

Zhaohui Wang 1 collaboration

Matteo Boretto 1 collaboration

Rosemary Millen 1 collaboration

Naveen Natesh 1 collaboration

Elena S Reckzeh 1 collaboration

Carolyn Hsu 1 collaboration

Marcos Negrete 1 collaboration

Haipei Yao 1 collaboration

William Quayle 1 collaboration

Brook E Heaton 1 collaboration

Alfred T Harding 1 collaboration

Shree Bose 1 collaboration

Else Driehuis 1 collaboration

Grecia O Rivera 1 collaboration

Donald Gex 1 collaboration

Jessica DeVilla 1 collaboration

Daisong Wang 1 collaboration

Athena Yeung 1 collaboration

Cait Hamele 1 collaboration

Amber Smith 1 collaboration

Eric Bankaitis 1 collaboration

Kun Xiang 1 collaboration

Shengli Ding 1 collaboration

Daniel Nelson 1 collaboration

Daniel Delubac 1 collaboration

Anne Rios 1 collaboration

Ralph Abi-Hachem 1 collaboration

David Jang 1 collaboration

Bradley J Goldstein 1 collaboration

Carolyn Glass 1 collaboration

Nicholas S Heaton 1 collaboration

David Hsu 1 collaboration

Xiling Shen 1 collaboration

Nico Battich 1 collaboration

Lenno Krenning 1 collaboration

Chloé S Baron 1 collaboration

Marvin E Tanenbaum 1 collaboration

Karl M Lyons 1 collaboration

Richard D Cannon 1 collaboration

Mahmoud M Bakr 1 collaboration

Robert M Love 1 collaboration

Adriana Martínez-Silgado 1 collaboration

Rasa Elmentaite 1 collaboration

Kylie R James 1 collaboration

Alexander Ross 1 collaboration

Georg A Busslinger 1 collaboration

Bas Ponsioen 1 collaboration

Amanda Andersson-Rolf 1 collaboration

Kai Kretzschmar 1 collaboration

Franka van der Linden 1 collaboration

Carmen Lopez-Iglesias 1 collaboration

Albert J R Heck 1 collaboration

Joachim Goedhart 1 collaboration

Hugo Snippert 1 collaboration

Matthias Zilbauer 1 collaboration

Sarah A Teichmann 1 collaboration

Axel Rosendahl Huber 1 collaboration

Arne van Hoeck 1 collaboration

Henry M Wood 1 collaboration

Jason Nomburg 1 collaboration

Carino Gurjao 1 collaboration

Freek Manders 1 collaboration

Guillaume Dalmasso 1 collaboration

Paul B Stege 1 collaboration

Fernanda L Paganelli 1 collaboration

Tomohiro Mizutani 1 collaboration

Yi Miao 1 collaboration

Stefan van der Elst 1 collaboration

None None 1 collaboration

K Christopher Garcia 1 collaboration

Janetta Top 1 collaboration

Rob J L Willems 1 collaboration

Marios Giannakis 1 collaboration

Richard Bonnet 1 collaboration

Phil Quirke 1 collaboration

Matthew Meyerson 1 collaboration

Ruben van Boxtel 1 collaboration

Talya L Dayton 1 collaboration

Nicolas Alcala 1 collaboration

Laura Moonen 1 collaboration

Lisanne den Hartigh 1 collaboration

Lise Mangiante 1 collaboration

Lisa Lap 1 collaboration

Antonella F M Dost 1 collaboration

Sonja Levy 1 collaboration

Rachel S van Leeuwaarde 1 collaboration

Wenzel M Hackeng 1 collaboration

Kris Samsom 1 collaboration

Catherine Voegele 1 collaboration

Alexandra Sexton-Oates 1 collaboration

Lisa Hillen 1 collaboration

Lodewijk A A Brosens 1 collaboration

Sylvie Lantuejoul 1 collaboration

Sridevi Jaksani 1 collaboration

Niels F M Kok 1 collaboration

Koen J Hartemink 1 collaboration

Houke M Klomp 1 collaboration

Inne H M Borel Rinkes 1 collaboration

Anne-Marie Dingemans 1 collaboration

Gerlof D Valk 1 collaboration

Menno R Vriens 1 collaboration

Wieneke Buikhuisen 1 collaboration

José van den Berg 1 collaboration

Margot Tesselaar 1 collaboration

Jules Derks 1 collaboration

Ernst Jan Speel 1 collaboration

Matthieu Foll 1 collaboration

Lynnette Fernández-Cuesta 1 collaboration

Carla Pou Casellas 1 collaboration

Carola M E Ammerlaan 1 collaboration

Charlotte J A Olde Hanhof 1 collaboration

Emre Dilmen 1 collaboration

Elise M G Meeder 1 collaboration

Joost G Hoenderop 1 collaboration

Stieneke van den Brink 1 collaboration

Xiaojing Chu 1 collaboration

Martin Jaeger 1 collaboration

Olivier B Bakker 1 collaboration

Raul Aguirre-Gamboa 1 collaboration

Marije Oosting 1 collaboration

Sanne P Smeekens 1 collaboration

Simone Moorlag 1 collaboration

Vera P Mourits 1 collaboration

Valerie A C M Koeken 1 collaboration

Charlotte de Bree 1 collaboration

Trees Jansen 1 collaboration

Ian T Mathews 1 collaboration

Khoi Dao 1 collaboration

Mahan Najhawan 1 collaboration

Jeramie D Watrous 1 collaboration

Irma Joosten 1 collaboration

Sonia Sharma 1 collaboration

Hans J P M Koenen 1 collaboration

Sebo Withoff 1 collaboration

Iris H Jonkers 1 collaboration

Romana T Netea-Maier 1 collaboration

Ramnik J Xavier 1 collaboration

Lude Franke 1 collaboration

Cheng-Jian Xu 1 collaboration

Leo A B Joosten 1 collaboration

Serena Sanna 1 collaboration

Mohit Jain 1 collaboration

Vinod Kumar 1 collaboration

Cisca Wijmenga 1 collaboration

Mihai G Netea 1 collaboration

Yang Li 1 collaboration

Adriana Martinez-Silgado 1 collaboration

Ninouk Akkerman 1 collaboration

Amy de Waal 1 collaboration

Devanjali Dutta 1 collaboration

Inha Heo 1 collaboration

Tim S Veth 1 collaboration

Hannah Gilliam-Vigh 1 collaboration

Steen S Poulsen 1 collaboration

Filip K Knop 1 collaboration

Romy van Acker 1 collaboration

Petra B van den Doel 1 collaboration

Martin E van Royen 1 collaboration

Jingshu Zhang 1 collaboration

Marius F Harter 1 collaboration

Timothy Recaldin 1 collaboration

Regine Gerard 1 collaboration

Blandine Avignon 1 collaboration

Yannik Bollen 1 collaboration

Cinzia Esposito 1 collaboration

Karolina Guja-Jarosz 1 collaboration

Kristina Kromer 1 collaboration

Adrian Filip 1 collaboration

Julien Aubert 1 collaboration

Anneliese Schneider 1 collaboration

Marina Bacac 1 collaboration

Michael Bscheider 1 collaboration

Nadine Stokar-Regenscheit 1 collaboration

Salvatore Piscuoglio 1 collaboration

Nikolche Gjorevski 1 collaboration

Sam Willemsen 1 collaboration

Johan van Es 1 collaboration

Helmuth Gehart 1 collaboration

Rutger Kok 1 collaboration

Xuan Zheng 1 collaboration

Indi Joore 1 collaboration

Susana Chuva de Sousa Lopes 1 collaboration

Jeroen van Zon 1 collaboration

Sander Tans 1 collaboration

Jelte van der Vaart 1 collaboration

Kèvin Knoops 1 collaboration

Raimond B G Ravelli 1 collaboration

J Paul van Schayck 1 collaboration

Hans Q Duimel 1 collaboration

Elly van Donselaar 1 collaboration

Samra Riesebosch 1 collaboration

Helma J H Kuijpers 1 collaboration

Miranda de Graaf 1 collaboration

Marion Koopmans 1 collaboration