Laura Seldeslachts

Affiliations

Biomedical MRI Unit/MoSAIC, Department of Imaging and Pathology, KU Leuven, 3000 Leuven, Belgium.

Publications (18)

Overcome Double Trouble: Baloxavir Marboxil Suppresses Influenza Thereby Mitigating Secondary Invasive Pulmonary Aspergillosis.

Journal of fungi (Basel, Switzerland)

Avec: Laura Seldeslachts , Cato Jacobs , Birger Tielemans , Eliane Vanhoffelen , Lauren Van der Sloten , Stephanie Humblet-Baron , Lieve Naesens , Katrien Lagrou , Erik Verbeken , Joost Wauters , Greetje Vande Velde

Comparing infectivity and virulence of emerging SARS-CoV-2 variants in Syrian hamsters.

EBioMedicine

Avec: Rana Abdelnabi , Robbert Boudewijns , Caroline S Foo , Laura Seldeslachts , Lorena Sanchez-Felipe , Xin Zhang , Leen Delang , Piet Maes , Suzanne J F Kaptein , Birgit Weynand , Greetje Vande Velde , Johan Neyts , Kai Dallmeier

Profiling Bacteria in the Lungs of Patients with Severe Influenza Versus COVID-19 with or without Aspergillosis.

American journal of respiratory and critical care medicine

Avec: Simon Feys , Martina Cardinali-Benigni , Hanne Moon Lauwers , Cato Jacobs , Annelies Stevaert , Samuel M Gonçalves , Cristina Cunha , Yves Debaveye , Greet Hermans , Jannes Heylen , Stephanie Humblet-Baron , Katrien Lagrou , Lenn Maessen , Philippe Meersseman , Marijke Peetermans , Alvaro Redondo-Rios , Laura Seldeslachts , Marick R Starick , Karin Thevissen , Greetje Vande Velde , Christophe Vandenbriele , Lore Vanderbeke , Alexander Wilmer , Lieve Naesens , Frank L van de Veerdonk , Johan Van Weyenbergh , Toni Gabaldón , Joost Wauters , Agostinho Carvalho

An affinity-enhanced, broadly neutralizing heavy chain-only antibody protects against SARS-CoV-2 infection in animal models.

Science translational medicine

Avec: Bert Schepens , Loes van Schie , Wim Nerinckx , Kenny Roose , Wander Van Breedam , Daria Fijalkowska , Simon Devos , Wannes Weyts , Sieglinde De Cae , Sandrine Vanmarcke , Chiara Lonigro , Hannah Eeckhaut , Dries Van Herpe , Jimmy Borloo , Ana Filipa Oliveira , João Paulo Portela Catani , Sarah Creytens , Dorien De Vlieger , Gitte Michielsen , Jackeline Cecilia Zavala Marchan , George D Moschonas , Iebe Rossey , Koen Sedeyn , Annelies Van Hecke , Xin Zhang , Lana Langendries , Sofie Jacobs , Sebastiaan Ter Horst , Laura Seldeslachts , Laurens Liesenborghs , Robbert Boudewijns , Hendrik Jan Thibaut , Kai Dallmeier , Greetje Vande Velde , Birgit Weynand , Julius Beer , Daniel Schnepf , Annette Ohnemus , Isabel Remory , Caroline S Foo , Rana Abdelnabi , Piet Maes , Suzanne J F Kaptein , Joana Rocha-Pereira , Dirk Jochmans , Leen Delang , Frank Peelman , Peter Staeheli , Martin Schwemmle , Nick Devoogdt , Dominique Tersago , Massimiliano Germani , James Heads , Alistair Henry , Andrew Popplewell , Mark Ellis , Kevin Brady , Alison Turner , Bruno Dombrecht , Catelijne Stortelers , Johan Neyts , Nico Callewaert , Xavier Saelens

STAT2 signaling restricts viral dissemination but drives severe pneumonia in SARS-CoV-2 infected hamsters.

Nature communications

Avec: Robbert Boudewijns , Hendrik Jan Thibaut , Suzanne J F Kaptein , Rong Li , Valentijn Vergote , Laura Seldeslachts , Johan Van Weyenbergh , Carolien De Keyzer , Lindsey Bervoets , Sapna Sharma , Laurens Liesenborghs , Ji Ma , Sander Jansen , Dominique Van Looveren , Thomas Vercruysse , Xinyu Wang , Dirk Jochmans , Erik Martens , Kenny Roose , Dorien De Vlieger , Bert Schepens , Tina Van Buyten , Sofie Jacobs , Yanan Liu , Joan Martí-Carreras , Bert Vanmechelen , Tony Wawina-Bokalanga , Leen Delang , Joana Rocha-Pereira , Lotte Coelmont , Winston Chiu , Pieter Leyssen , Elisabeth Heylen , Dominique Schols , Lanjiao Wang , Lila Close , Jelle Matthijnssens , Marc Van Ranst , Veerle Compernolle , Georg Schramm , Koen Van Laere , Xavier Saelens , Nico Callewaert , Ghislain Opdenakker , Piet Maes , Birgit Weynand , Christopher Cawthorne , Greetje Vande Velde , Zhongde Wang , Johan Neyts , Kai Dallmeier

A single-dose live-attenuated YF17D-vectored SARS-CoV-2 vaccine candidate.

Nature

Avec: Lorena Sanchez-Felipe , Thomas Vercruysse , Sapna Sharma , Ji Ma , Viktor Lemmens , Dominique Van Looveren , Mahadesh Prasad Arkalagud Javarappa , Robbert Boudewijns , Bert Malengier-Devlies , Laurens Liesenborghs , Suzanne J F Kaptein , Carolien De Keyzer , Lindsey Bervoets , Sarah Debaveye , Madina Rasulova , Laura Seldeslachts , Li-Hsin Li , Sander Jansen , Michael Bright Yakass , Babs E Verstrepen , Kinga P Böszörményi , Gwendoline Kiemenyi-Kayere , Nikki van Driel , Osbourne Quaye , Xin Zhang , Sebastiaan Ter Horst , Niraj Mishra , Ward Deboutte , Jelle Matthijnssens , Lotte Coelmont , Corinne Vandermeulen , Elisabeth Heylen , Valentijn Vergote , Dominique Schols , Zhongde Wang , Willy Bogers , Thijs Kuiken , Ernst Verschoor , Christopher Cawthorne , Koen Van Laere , Ghislain Opdenakker , Greetje Vande Velde , Birgit Weynand , Dirk E Teuwen , Patrick Matthys , Johan Neyts , Hendrik Jan Thibaut , Kai Dallmeier

Lung epithelial and myeloid innate immunity in influenza-associated or COVID-19-associated pulmonary aspergillosis: an observational study.

The Lancet. Respiratory medicine

Avec: Simon Feys , Samuel M Gonçalves , Mona Khan , Sumin Choi , Bram Boeckx , Denis Chatelain , Cristina Cunha , Yves Debaveye , Greet Hermans , Marjan Hertoghs , Stephanie Humblet-Baron , Cato Jacobs , Katrien Lagrou , Lukas Marcelis , Julien Maizel , Philippe Meersseman , Rémy Nyga , Laura Seldeslachts , Marick Rodrigues Starick , Karin Thevissen , Christophe Vandenbriele , Lore Vanderbeke , Greetje Vande Velde , Niels Van Regenmortel , Arno Vanstapel , Sam Vanmassenhove , Alexander Wilmer , Frank L Van De Veerdonk , Gert De Hertogh , Peter Mombaerts , Diether Lambrechts , Agostinho Carvalho , Johan Van Weyenbergh , Joost Wauters

A Multimodal Imaging-Supported Down Syndrome Mouse Model of RSV Infection.

Viruses

Avec: Birger Tielemans , Lander De Herdt , Emilie Pollenus , Emiel Vanhulle , Laura Seldeslachts , Fopke Marain , Flore Belmans , Kaveh Ahookhosh , Jeroen Vanoirbeek , Kurt Vermeire , Philippe E Van den Steen , Greetje Vande Velde

Damping excessive viral-induced IFN-γ rescues the impaired anti-Aspergillus host immune response in influenza-associated pulmonary aspergillosis.

EBioMedicine

Avec: Laura Seldeslachts , Frederik Staels , Marina Gkountzinopoulou , Cato Jacobs , Birger Tielemans , Eliane Vanhoffelen , Agustin Reséndiz-Sharpe , Lander De Herdt , Jeason Haughton , Teresa Prezzemolo , Oliver Burton , Simon Feys , Frank L van de Veerdonk , Agostinho Carvalho , Lieve Naesens , Patrick Matthys , Katrien Lagrou , Erik Verbeken , Georgios Chamilos , Joost Wauters , Stephanie Humblet-Baron , Greetje Vande Velde

Defective Sec61α1 underlies a novel cause of autosomal dominant severe congenital neutropenia.

The Journal of allergy and clinical immunology

Avec: Erika Van Nieuwenhove , John S Barber , Julika Neumann , Elien Smeets , Mathijs Willemsen , Emanuela Pasciuto , Teresa Prezzemolo , Vasiliki Lagou , Laura Seldeslachts , Bert Malengier-Devlies , Mieke Metzemaekers , Sarah Haßdenteufel , Axelle Kerstens , Rob van der Kant , Frederic Rousseau , Joost Schymkowitz , Daniele Di Marino , Sven Lang , Richard Zimmermann , Susan Schlenner , Sebastian Munck , Paul Proost , Patrick Matthys , Christine Devalck , Nancy Boeckx , Frank Claessens , Carine Wouters , Stephanie Humblet-Baron , Isabelle Meyts , Adrian Liston

Lung Functioning and Inflammation in a Mouse Model of Systemic Juvenile Idiopathic Arthritis.

Frontiers in immunology

Avec: Bert Malengier-Devlies , Tatjana Decaesteker , Kaat Dekoster , Arno Vanstapel , Kourosh Ahmadzadeh , Fariba Poosti , Tania Mitera , Laura Seldeslachts , Erik Verbeken , Carine Wouters , Greetje Vande Velde , Jeroen Vanoirbeek , Patrick Matthys

Favipiravir at high doses has potent antiviral activity in SARS-CoV-2-infected hamsters, whereas hydroxychloroquine lacks activity.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Suzanne J F Kaptein , Sofie Jacobs , Lana Langendries , Laura Seldeslachts , Sebastiaan Ter Horst , Laurens Liesenborghs , Bart Hens , Valentijn Vergote , Elisabeth Heylen , Karine Barthelemy , Elke Maas , Carolien De Keyzer , Lindsey Bervoets , Jasper Rymenants , Tina Van Buyten , Xin Zhang , Rana Abdelnabi , Juanita Pang , Rachel Williams , Hendrik Jan Thibaut , Kai Dallmeier , Robbert Boudewijns , Jens Wouters , Patrick Augustijns , Nick Verougstraete , Christopher Cawthorne , Judith Breuer , Caroline Solas , Birgit Weynand , Pieter Annaert , Isabel Spriet , Greetje Vande Velde , Johan Neyts , Joana Rocha-Pereira , Leen Delang

Early oseltamivir reduces risk for influenza-associated aspergillosis in a double-hit murine model.

Virulence

Avec: Laura Seldeslachts , Lore Vanderbeke , Astrid Fremau , Agustin Reséndiz-Sharpe , Cato Jacobs , Bo Laeveren , Tessa Ostyn , Lieve Naesens , Matthias Brock , Frank L Van De Veerdonk , Stephanie Humblet-Baron , Erik Verbeken , Katrien Lagrou , Joost Wauters , Greetje Vande Velde

CSF1R inhibition by PLX5622 reduces pulmonary fungal infection by depleting MHCII

Mucosal immunology

Avec: Sally H Mohamed , Eliane Vanhoffelen , Man Shun Fu , Pui Hei Lau , Sofia Hain , Laura Seldeslachts , Emilie Cosway , Graham Anderson , Laura McCulloch , Greetje Vande Velde , Rebecca A Drummond

Use of Micro-Computed Tomography to Visualize and Quantify COVID-19 Vaccine Efficiency in Free-Breathing Hamsters.

Methods in molecular biology (Clifton, N.J.)

Avec: Laura Seldeslachts , Christopher Cawthorne , Suzanne F Kaptein , Robbert Boudewijns , Hendrik Jan Thibaut , Lorena Sanchez Felipe , Sapna Sharma , Georg Schramm , Birgit Weynand , Kai Dallmeier , Greetje Vande Velde

Longitudinal multimodal imaging-compatible mouse model of triazole-sensitive and -resistant invasive pulmonary aspergillosis.

Disease models & mechanisms

Avec: Agustin Resendiz-Sharpe , Roberta Peres da Silva , Elena Geib , Lore Vanderbeke , Laura Seldeslachts , Charlien Hupko , Matthias Brock , Katrien Lagrou , Greetje Vande Velde

OTULIN haploinsufficiency predisposes to environmentally directed inflammation.

Frontiers in immunology

Avec: Frederik Staels , Leoni Bücken , Leana De Vuyst , Mathijs Willemsen , Erika Van Nieuwenhove , Margaux Gerbaux , Julika Neumann , Vanshika Malviya , Lize Van Meerbeeck , Jeason Haughton , Laura Seldeslachts , Mieke Gouwy , Kimberly Martinod , Greetje Vande Velde , Paul Proost , Lidia Yshii , Susan Schlenner , Rik Schrijvers , Adrian Liston , Stephanie Humblet-Baron

Influenza-associated and COVID-19-associated pulmonary aspergillosis in critically ill patients.

The Lancet. Respiratory medicine

Avec: Simon Feys , Agostinho Carvalho , Cornelius J Clancy , Jean-Pierre Gangneux , Martin Hoenigl , Katrien Lagrou , Bart J A Rijnders , Laura Seldeslachts , Lore Vanderbeke , Frank L van de Veerdonk , Paul E Verweij , Joost Wauters

Réseau de co-auteurs

Greetje Vande Velde 16 collaborations

Stephanie Humblet-Baron 7 collaborations

Katrien Lagrou 7 collaborations

Joost Wauters 6 collaborations

Robbert Boudewijns 6 collaborations

Birgit Weynand 6 collaborations

Kai Dallmeier 6 collaborations

Cato Jacobs 5 collaborations

Suzanne J F Kaptein 5 collaborations

Johan Neyts 5 collaborations

Lore Vanderbeke 5 collaborations

Hendrik Jan Thibaut 5 collaborations

Lieve Naesens 4 collaborations

Erik Verbeken 4 collaborations

Xin Zhang 4 collaborations

Leen Delang 4 collaborations

Simon Feys 4 collaborations

Agostinho Carvalho 4 collaborations

Laurens Liesenborghs 4 collaborations

Christopher Cawthorne 4 collaborations

Patrick Matthys 4 collaborations

Birger Tielemans 3 collaborations

Eliane Vanhoffelen 3 collaborations

Rana Abdelnabi 3 collaborations

Piet Maes 3 collaborations

Frank L van de Veerdonk 3 collaborations

Johan Van Weyenbergh 3 collaborations

Sofie Jacobs 3 collaborations

Sebastiaan Ter Horst 3 collaborations

Joana Rocha-Pereira 3 collaborations

Valentijn Vergote 3 collaborations

Carolien De Keyzer 3 collaborations

Lindsey Bervoets 3 collaborations

Sapna Sharma 3 collaborations

Elisabeth Heylen 3 collaborations

Bert Malengier-Devlies 3 collaborations

Caroline S Foo 2 collaborations

Lorena Sanchez-Felipe 2 collaborations

Samuel M Gonçalves 2 collaborations

Cristina Cunha 2 collaborations

Yves Debaveye 2 collaborations

Greet Hermans 2 collaborations

Philippe Meersseman 2 collaborations

Karin Thevissen 2 collaborations

Christophe Vandenbriele 2 collaborations

Alexander Wilmer 2 collaborations

Bert Schepens 2 collaborations

Kenny Roose 2 collaborations

Dorien De Vlieger 2 collaborations

Lana Langendries 2 collaborations

Dirk Jochmans 2 collaborations

Nico Callewaert 2 collaborations

Xavier Saelens 2 collaborations

Ji Ma 2 collaborations

Sander Jansen 2 collaborations

Dominique Van Looveren 2 collaborations

Thomas Vercruysse 2 collaborations

Tina Van Buyten 2 collaborations

Lotte Coelmont 2 collaborations

Dominique Schols 2 collaborations

Jelle Matthijnssens 2 collaborations

Georg Schramm 2 collaborations

Koen Van Laere 2 collaborations

Ghislain Opdenakker 2 collaborations

Zhongde Wang 2 collaborations

Arno Vanstapel 2 collaborations

Frank L Van De Veerdonk 2 collaborations

Lander De Herdt 2 collaborations

Jeroen Vanoirbeek 2 collaborations

Frederik Staels 2 collaborations

Agustin Reséndiz-Sharpe 2 collaborations

Jeason Haughton 2 collaborations

Teresa Prezzemolo 2 collaborations

Erika Van Nieuwenhove 2 collaborations

Julika Neumann 2 collaborations

Mathijs Willemsen 2 collaborations

Susan Schlenner 2 collaborations

Paul Proost 2 collaborations

Carine Wouters 2 collaborations

Adrian Liston 2 collaborations

Matthias Brock 2 collaborations

Lauren Van der Sloten 1 collaboration

Martina Cardinali-Benigni 1 collaboration

Hanne Moon Lauwers 1 collaboration

Annelies Stevaert 1 collaboration

Jannes Heylen 1 collaboration

Lenn Maessen 1 collaboration

Marijke Peetermans 1 collaboration

Alvaro Redondo-Rios 1 collaboration

Marick R Starick 1 collaboration

Toni Gabaldón 1 collaboration

Loes van Schie 1 collaboration

Wim Nerinckx 1 collaboration

Wander Van Breedam 1 collaboration

Daria Fijalkowska 1 collaboration

Simon Devos 1 collaboration

Wannes Weyts 1 collaboration

Sieglinde De Cae 1 collaboration

Sandrine Vanmarcke 1 collaboration

Chiara Lonigro 1 collaboration

Hannah Eeckhaut 1 collaboration

Dries Van Herpe 1 collaboration

Jimmy Borloo 1 collaboration

Ana Filipa Oliveira 1 collaboration

João Paulo Portela Catani 1 collaboration

Sarah Creytens 1 collaboration

Gitte Michielsen 1 collaboration

Jackeline Cecilia Zavala Marchan 1 collaboration

George D Moschonas 1 collaboration

Iebe Rossey 1 collaboration

Koen Sedeyn 1 collaboration

Annelies Van Hecke 1 collaboration

Julius Beer 1 collaboration

Daniel Schnepf 1 collaboration

Annette Ohnemus 1 collaboration

Isabel Remory 1 collaboration

Frank Peelman 1 collaboration

Peter Staeheli 1 collaboration

Martin Schwemmle 1 collaboration

Nick Devoogdt 1 collaboration

Dominique Tersago 1 collaboration

Massimiliano Germani 1 collaboration

James Heads 1 collaboration

Alistair Henry 1 collaboration

Andrew Popplewell 1 collaboration

Mark Ellis 1 collaboration

Kevin Brady 1 collaboration

Alison Turner 1 collaboration

Bruno Dombrecht 1 collaboration

Catelijne Stortelers 1 collaboration

Rong Li 1 collaboration

Xinyu Wang 1 collaboration

Erik Martens 1 collaboration

Yanan Liu 1 collaboration

Joan Martí-Carreras 1 collaboration

Bert Vanmechelen 1 collaboration

Tony Wawina-Bokalanga 1 collaboration

Winston Chiu 1 collaboration

Pieter Leyssen 1 collaboration

Lanjiao Wang 1 collaboration

Lila Close 1 collaboration

Marc Van Ranst 1 collaboration

Veerle Compernolle 1 collaboration

Viktor Lemmens 1 collaboration

Mahadesh Prasad Arkalagud Javarappa 1 collaboration

Sarah Debaveye 1 collaboration

Madina Rasulova 1 collaboration

Li-Hsin Li 1 collaboration

Michael Bright Yakass 1 collaboration

Babs E Verstrepen 1 collaboration

Kinga P Böszörményi 1 collaboration

Gwendoline Kiemenyi-Kayere 1 collaboration

Nikki van Driel 1 collaboration

Osbourne Quaye 1 collaboration

Niraj Mishra 1 collaboration

Ward Deboutte 1 collaboration

Corinne Vandermeulen 1 collaboration

Willy Bogers 1 collaboration

Thijs Kuiken 1 collaboration

Ernst Verschoor 1 collaboration

Dirk E Teuwen 1 collaboration

Mona Khan 1 collaboration

Sumin Choi 1 collaboration

Bram Boeckx 1 collaboration

Denis Chatelain 1 collaboration

Marjan Hertoghs 1 collaboration

Lukas Marcelis 1 collaboration

Julien Maizel 1 collaboration

Rémy Nyga 1 collaboration

Marick Rodrigues Starick 1 collaboration

Niels Van Regenmortel 1 collaboration

Sam Vanmassenhove 1 collaboration

Gert De Hertogh 1 collaboration

Peter Mombaerts 1 collaboration

Diether Lambrechts 1 collaboration

Emilie Pollenus 1 collaboration

Emiel Vanhulle 1 collaboration

Fopke Marain 1 collaboration

Flore Belmans 1 collaboration

Kaveh Ahookhosh 1 collaboration

Kurt Vermeire 1 collaboration

Philippe E Van den Steen 1 collaboration

Marina Gkountzinopoulou 1 collaboration

Oliver Burton 1 collaboration

Georgios Chamilos 1 collaboration

John S Barber 1 collaboration

Elien Smeets 1 collaboration

Emanuela Pasciuto 1 collaboration

Vasiliki Lagou 1 collaboration

Mieke Metzemaekers 1 collaboration

Sarah Haßdenteufel 1 collaboration

Axelle Kerstens 1 collaboration

Rob van der Kant 1 collaboration

Frederic Rousseau 1 collaboration

Joost Schymkowitz 1 collaboration

Daniele Di Marino 1 collaboration

Sven Lang 1 collaboration

Richard Zimmermann 1 collaboration

Sebastian Munck 1 collaboration

Christine Devalck 1 collaboration

Nancy Boeckx 1 collaboration

Frank Claessens 1 collaboration

Isabelle Meyts 1 collaboration

Tatjana Decaesteker 1 collaboration

Kaat Dekoster 1 collaboration

Kourosh Ahmadzadeh 1 collaboration

Fariba Poosti 1 collaboration

Tania Mitera 1 collaboration

Bart Hens 1 collaboration

Karine Barthelemy 1 collaboration

Elke Maas 1 collaboration

Jasper Rymenants 1 collaboration

Juanita Pang 1 collaboration

Rachel Williams 1 collaboration

Jens Wouters 1 collaboration

Patrick Augustijns 1 collaboration

Nick Verougstraete 1 collaboration

Judith Breuer 1 collaboration

Caroline Solas 1 collaboration

Pieter Annaert 1 collaboration

Isabel Spriet 1 collaboration

Astrid Fremau 1 collaboration

Bo Laeveren 1 collaboration

Tessa Ostyn 1 collaboration

Sally H Mohamed 1 collaboration

Man Shun Fu 1 collaboration

Pui Hei Lau 1 collaboration

Sofia Hain 1 collaboration

Emilie Cosway 1 collaboration

Graham Anderson 1 collaboration

Laura McCulloch 1 collaboration

Rebecca A Drummond 1 collaboration

Suzanne F Kaptein 1 collaboration

Lorena Sanchez Felipe 1 collaboration

Agustin Resendiz-Sharpe 1 collaboration

Roberta Peres da Silva 1 collaboration

Elena Geib 1 collaboration

Charlien Hupko 1 collaboration

Leoni Bücken 1 collaboration

Leana De Vuyst 1 collaboration

Margaux Gerbaux 1 collaboration

Vanshika Malviya 1 collaboration

Lize Van Meerbeeck 1 collaboration

Mieke Gouwy 1 collaboration

Kimberly Martinod 1 collaboration

Lidia Yshii 1 collaboration

Rik Schrijvers 1 collaboration

Cornelius J Clancy 1 collaboration

Jean-Pierre Gangneux 1 collaboration

Martin Hoenigl 1 collaboration

Bart J A Rijnders 1 collaboration

Paul E Verweij 1 collaboration