M Merlos

Affiliations

Dermatology Department, Reference Centre for Rare Skin Diseases, Larrey Hospital, University P Sabatier, Toulouse, France.

Publications (27)

Burden of itch in ichthyosis: a multicentre study in 94 patients.

Journal of the European Academy of Dermatology and Venereology : JEADV

Avec: A M De Palma , J Mazereeuw-Hautier , K Giehl , A Hernández-Martin , M Merlos , P Moons , M A Morren

Development of a Novel σ

ACS chemical neuroscience

Avec: Xavier Morató , Víctor Fernández-Dueñas , Pilar Pérez-Villamor , Marta Valle-León , José Miguel Vela , Manuel Merlos , Javier Burgueño , Francisco Ciruela

Urinary bladder sigma-1 receptors: A new target for cystitis treatment.

Pharmacological research

Avec: Rafael González-Cano , Antonia Artacho-Cordón , Lucía Romero , Miguel A Tejada , Francisco R Nieto , Manuel Merlos , Francisco J Cañizares , Cruz M Cendán , Eduardo Fernández-Segura , José M Baeyens

Supraspinal and Peripheral, but Not Intrathecal, σ

Frontiers in pharmacology

Avec: Alba Vidal-Torres , Begoña Fernández-Pastor , Alicia Carceller , José Miguel Vela , Manuel Merlos , Daniel Zamanillo

Blockade of the Sigma-1 Receptor Relieves Cognitive and Emotional Impairments Associated to Chronic Osteoarthritis Pain.

Frontiers in pharmacology

Avec: Mireia Carcolé , Daniel Zamanillo , Manuel Merlos , Begoña Fernández-Pastor , David Cabañero , Rafael Maldonado

A New Model of Sensorial Neuron-Like Cells for HTS of Novel Analgesics for Neuropathic Pain.

SLAS discovery : advancing life sciences R & D

Avec: Antón L Martínez , José Brea , Xavier Monroy , Manuel Merlos , Javier Burgueño , María Isabel Loza

Development of a novel in vitro assay to screen for neuroprotective drugs against iatrogenic neurite shortening.

PloS one

Avec: Antón L Martínez , José Brea , Mateo Barro , Xavier Monroy , Manuel Merlos , Javier Burgueño , María Isabel Loza

Botulinum toxin injections as an effective treatment for patients with intertriginous Hailey-Hailey or Darier disease: an open-label 6-month pilot interventional study.

Orphanet journal of rare diseases

Avec: Isabelle Dreyfus , Aude Maza , Lauriane Rodriguez , Margot Merlos , Hélène Texier , Vanessa Rousseau , Agnès Sommet , Juliette Mazereeuw-Hautier

Co-crystal of tramadol-celecoxib: preclinical and clinical evaluation of a novel analgesic.

Expert opinion on investigational drugs

Avec: Neus Gascon , Carmen Almansa , Manuel Merlos , José Miguel Vela , Gregorio Encina , Adelaida Morte , Kevin Smith , Carlos Plata-Salamán

May a sigma-1 antagonist improve neuropathic signs induced by cisplatin and vincristine in rats?

European journal of pain (London, England)

Avec: Nancy Paniagua , Carlos Goicoechea , Raquel Abalo , Visitacion López-Miranda , J Miguel Vela , Manuel Merlos , María Isabel Martín Fontelles , Rocio Girón

Identification of Sodium Transients Through Na

Frontiers in cellular neuroscience

Avec: Antón L Martínez , José Brea , Eduardo Domínguez , María J Varela , Catarina Allegue , Raquel Cruz , Xavier Monroy , Manuel Merlos , Javier Burgueño , Ángel Carracedo , María Isabel Loza

Long-Lasting Nociplastic Pain Modulation by Repeated Administration of Sigma-1 Receptor Antagonist BD1063 in Fibromyalgia-like Mouse Models.

International journal of molecular sciences

Avec: Beltrán Álvarez-Pérez , Anna Bagó-Mas , Meritxell Deulofeu , José Miguel Vela , Manuel Merlos , Enrique Verdú , Pere Boadas-Vaello

Long-lasting reflexive and nonreflexive pain responses in two mouse models of fibromyalgia-like condition.

Scientific reports

Avec: Beltrán Álvarez-Pérez , Meritxell Deulofeu , Judit Homs , Manuel Merlos , José Miguel Vela , Enrique Verdú , Pere Boadas-Vaello

Bispecific sigma-1 receptor antagonism and mu-opioid receptor partial agonism: WLB-73502, an analgesic with improved efficacy and safety profile compared to strong opioids.

Acta pharmaceutica Sinica. B

Avec: Alba Vidal-Torres , Begoña Fernández-Pastor , Mónica García , Eva Ayet , Anna Cabot , Javier Burgueño , Xavier Monroy , Bertrand Aubel , Xavier Codony , Luz Romero , Rosalía Pascual , Maria Teresa Serafini , Gregorio Encina , Carmen Almansa , Daniel Zamanillo , Manuel Merlos , José Miguel Vela

Ligands Exert Biased Activity to Regulate Sigma 1 Receptor Interactions With Cationic TRPA1, TRPV1, and TRPM8 Channels.

Frontiers in pharmacology

Avec: Elsa Cortés-Montero , Pilar Sánchez-Blázquez , Yara Onetti , Manuel Merlos , Javier Garzón

Discovery of EST73502, a Dual μ-Opioid Receptor Agonist and σ

Journal of medicinal chemistry

Avec: Mónica García , Marina Virgili , Mònica Alonso , Carles Alegret , Joan Farran , Begoña Fernández , Magda Bordas , Rosalia Pascual , Javier Burgueño , Alba Vidal-Torres , Antonio R Fernández de Henestrosa , Eva Ayet , Manuel Merlos , Jose Miguel Vela , Carlos R Plata-Salamán , Carmen Almansa

Neuroprotective Effects of Sigma 1 Receptor Ligands on Motoneuron Death after Spinal Root Injury in Mice.

International journal of molecular sciences

Avec: Núria Gaja-Capdevila , Neus Hernández , Daniel Zamanillo , Jose Miguel Vela , Manuel Merlos , Xavier Navarro , Mireia Herrando-Grabulosa

Comprehensive Preclinical Assessment of Sensory, Functional, Motivational-Affective, and Neurochemical Outcomes in Neuropathic Pain: The Case of the Sigma-1 Receptor.

ACS pharmacology & translational science

Avec: Beatriz de la Puente , Daniel Zamanillo , Luz Romero , Alicia Carceller , José Miguel Vela , Manuel Merlos , Enrique Portillo-Salido

EST79232 and EST79376, Two Novel Sigma-1 Receptor Ligands, Exert Neuroprotection on Models of Motoneuron Degeneration.

International journal of molecular sciences

Avec: Núria Gaja-Capdevila , Neus Hernández , Sandra Yeste , Raquel F Reinoso , Javier Burgueño , Ana Montero , Manuel Merlos , José M Vela , Mireia Herrando-Grabulosa , Xavier Navarro

Discovery of WLB-89462, a New Drug-like and Highly Selective σ

Journal of medicinal chemistry

Avec: Ute Christmann , José Luis Díaz , Rosalia Pascual , Magda Bordas , Inés Álvarez , Xavier Monroy , Mónica Porras , Sandra Yeste , Raquel F Reinoso , Manuel Merlos , José Miguel Vela , Carmen Almansa

Resilience to Pain-Related Depression in σ

ACS chemical neuroscience

Avec: Beatriz de la Puente , Daniel Zamanillo , Luz Romero , Alicia Carceller , José Miguel Vela , Manuel Merlos , Enrique Portillo-Salido

Outside-in regulation of the readily releasable pool of synaptic vesicles by α2δ-1.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Avec: Pablo Martínez San Segundo , Beatrice Terni , Javier Burgueño , Xavier Monroy , Albert Dordal , Manuel Merlos , Artur Llobet

Sigma-1 receptor modulates neuroinflammation associated with mechanical hypersensitivity and opioid tolerance in a mouse model of osteoarthritis pain.

British journal of pharmacology

Avec: Mireia Carcolé , Sami Kummer , Leonor Gonçalves , Daniel Zamanillo , Manuel Merlos , Anthony H Dickenson , Begoña Fernández-Pastor , David Cabañero , Rafael Maldonado

Repeated Sigma-1 Receptor Antagonist MR309 Administration Modulates Central Neuropathic Pain Development After Spinal Cord Injury in Mice.

Frontiers in pharmacology

Avec: Sílvia Castany , Xavier Codony , Daniel Zamanillo , Manuel Merlos , Enrique Verdú , Pere Boadas-Vaello

The Sigma 2 receptor promotes and the Sigma 1 receptor inhibits mu-opioid receptor-mediated antinociception.

Molecular brain

Avec: Pilar Sánchez-Blázquez , Elsa Cortés-Montero , María Rodríguez-Muñoz , Manuel Merlos , Javier Garzón-Niño

Identification of Novel Regulators of Zalcitabine-Induced Neuropathic Pain.

ACS chemical neuroscience

Avec: Antón L Martínez , José Brea , Eduardo Domínguez , María J Varela , Marta Cimadevila , Catarina Allegue , Raquel Cruz , Xavier Monroy , Manuel Merlos , Javier Burgueño , Ángel Carracedo , María I Loza

In Vitro Models for Neuropathic Pain Phenotypic Screening in Brain Therapeutics.

Pharmacological research

Avec: A L Martínez , J Brea , D López , N Cosme , M Barro , X Monroy , J Burgueño , M Merlos , M I Loza

Réseau de co-auteurs

Manuel Merlos 24 collaborations

José Miguel Vela 9 collaborations

Javier Burgueño 9 collaborations

Daniel Zamanillo 8 collaborations

Xavier Monroy 7 collaborations

Begoña Fernández-Pastor 4 collaborations

Antón L Martínez 4 collaborations

José Brea 4 collaborations

Carmen Almansa 4 collaborations

Alba Vidal-Torres 3 collaborations

Alicia Carceller 3 collaborations

María Isabel Loza 3 collaborations

Enrique Verdú 3 collaborations

Pere Boadas-Vaello 3 collaborations

Luz Romero 3 collaborations

Mireia Carcolé 2 collaborations

David Cabañero 2 collaborations

Rafael Maldonado 2 collaborations

Gregorio Encina 2 collaborations

Eduardo Domínguez 2 collaborations

María J Varela 2 collaborations

Catarina Allegue 2 collaborations

Raquel Cruz 2 collaborations

Ángel Carracedo 2 collaborations

Beltrán Álvarez-Pérez 2 collaborations

Meritxell Deulofeu 2 collaborations

Mónica García 2 collaborations

Eva Ayet 2 collaborations

Xavier Codony 2 collaborations

Elsa Cortés-Montero 2 collaborations

Pilar Sánchez-Blázquez 2 collaborations

Magda Bordas 2 collaborations

Rosalia Pascual 2 collaborations

Jose Miguel Vela 2 collaborations

Núria Gaja-Capdevila 2 collaborations

Neus Hernández 2 collaborations

Xavier Navarro 2 collaborations

Mireia Herrando-Grabulosa 2 collaborations

Beatriz de la Puente 2 collaborations

Enrique Portillo-Salido 2 collaborations

Sandra Yeste 2 collaborations

Raquel F Reinoso 2 collaborations

A M De Palma 1 collaboration

J Mazereeuw-Hautier 1 collaboration

K Giehl 1 collaboration

A Hernández-Martin 1 collaboration

P Moons 1 collaboration

M A Morren 1 collaboration

Xavier Morató 1 collaboration

Víctor Fernández-Dueñas 1 collaboration

Pilar Pérez-Villamor 1 collaboration

Marta Valle-León 1 collaboration

Francisco Ciruela 1 collaboration

Rafael González-Cano 1 collaboration

Antonia Artacho-Cordón 1 collaboration

Lucía Romero 1 collaboration

Miguel A Tejada 1 collaboration

Francisco R Nieto 1 collaboration

Francisco J Cañizares 1 collaboration

Cruz M Cendán 1 collaboration

Eduardo Fernández-Segura 1 collaboration

José M Baeyens 1 collaboration

Mateo Barro 1 collaboration

Isabelle Dreyfus 1 collaboration

Aude Maza 1 collaboration

Lauriane Rodriguez 1 collaboration

Margot Merlos 1 collaboration

Hélène Texier 1 collaboration

Vanessa Rousseau 1 collaboration

Agnès Sommet 1 collaboration

Juliette Mazereeuw-Hautier 1 collaboration

Neus Gascon 1 collaboration

Adelaida Morte 1 collaboration

Kevin Smith 1 collaboration

Carlos Plata-Salamán 1 collaboration

Nancy Paniagua 1 collaboration

Carlos Goicoechea 1 collaboration

Raquel Abalo 1 collaboration

Visitacion López-Miranda 1 collaboration

J Miguel Vela 1 collaboration

María Isabel Martín Fontelles 1 collaboration

Rocio Girón 1 collaboration

Anna Bagó-Mas 1 collaboration

Judit Homs 1 collaboration

Anna Cabot 1 collaboration

Bertrand Aubel 1 collaboration

Rosalía Pascual 1 collaboration

Maria Teresa Serafini 1 collaboration

Yara Onetti 1 collaboration

Javier Garzón 1 collaboration

Marina Virgili 1 collaboration

Mònica Alonso 1 collaboration

Carles Alegret 1 collaboration

Joan Farran 1 collaboration

Begoña Fernández 1 collaboration

Antonio R Fernández de Henestrosa 1 collaboration

Carlos R Plata-Salamán 1 collaboration

Ana Montero 1 collaboration

José M Vela 1 collaboration

Ute Christmann 1 collaboration

José Luis Díaz 1 collaboration

Inés Álvarez 1 collaboration

Mónica Porras 1 collaboration

Pablo Martínez San Segundo 1 collaboration

Beatrice Terni 1 collaboration

Albert Dordal 1 collaboration

Artur Llobet 1 collaboration

Sami Kummer 1 collaboration

Leonor Gonçalves 1 collaboration

Anthony H Dickenson 1 collaboration

Sílvia Castany 1 collaboration

María Rodríguez-Muñoz 1 collaboration

Javier Garzón-Niño 1 collaboration

Marta Cimadevila 1 collaboration

María I Loza 1 collaboration

A L Martínez 1 collaboration

J Brea 1 collaboration

D López 1 collaboration

N Cosme 1 collaboration

M Barro 1 collaboration

X Monroy 1 collaboration

J Burgueño 1 collaboration

M I Loza 1 collaboration