M Opdam

Affiliations

Department of Molecular Pathology, Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX, Amsterdam, Netherlands.

Publications (20)

Response of metastatic mouse invasive lobular carcinoma to mTOR inhibition is partly mediated by the adaptive immune system.

Oncoimmunology

Avec: Sjoerd Klarenbeek , Chris W Doornebal , Sjors M Kas , Nicola Bonzanni , Jinhyuk Bhin , Tanya M Braumuller , Ingrid van der Heijden , Mark Opdam , Philip C Schouten , Kelly Kersten , Roebi de Bruijn , Daniel Zingg , Julia Yemelyanenko , Lodewyk F A Wessels , Karin E de Visser , Jos Jonkers

Differential Survival and Therapy Benefit of Patients with Breast Cancer Are Characterized by Distinct Epithelial and Immune Cell Microenvironments.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Lennart Kester , Danielle Seinstra , Annelot G J van Rossum , Claire Vennin , Marlous Hoogstraat , Daphne van der Velden , Mark Opdam , Erik van Werkhoven , Kerstin Hahn , Iris Nederlof , Ester H Lips , Ingrid A M Mandjes , A Elise van Leeuwen-Stok , Sander Canisius , Harm van Tinteren , Alex L T Imholz , Johanneke E A Portielje , Monique E M M Bos , Sandra D Bakker , Emiel J Rutgers , Hugo M Horlings , Jelle Wesseling , Emile E Voest , Lodewyk F A Wessels , Marleen Kok , Hendrika M Oosterkamp , Alexander van Oudenaarden , Sabine C Linn , Jacco van Rheenen

Effect of metformin use on clinical outcomes and serum urate in gout patients with diabetes mellitus: a retrospective cohort study.

BMC rheumatology

Avec: Frouwke Veenstra , Lise M Verhoef , Merel Opdam , Alfons A den Broeder , Wing-Yee Kwok , Inger L Meek , Cornelia H M van den Ende , Marcel Flendrie , Noortje van Herwaarden

Dissecting the predictive value of MAPK/AKT/estrogen-receptor phosphorylation axis in primary breast cancer to treatment response for tamoxifen over exemestane: a Translational Report of the Intergroup Exemestane Study (IES)-PathIES.

Breast cancer research and treatment

Avec: Zsolt Szijgyarto , Koen D Flach , Mark Opdam , Carlo Palmieri , Sabine C Linn , Jelle Wesseling , Simak Ali , Judith M Bliss , Maggie Chon U Cheang , Wilbert Zwart , R Charles Coombes

Hierarchical clustering of PI3K and MAPK pathway proteins in breast cancer intrinsic subtypes.

APMIS : acta pathologica, microbiologica, et immunologica Scandinavica

Avec: Dinja T Kruger , Mark Opdam , Joyce Sanders , Vincent van der Noort , Epie Boven , Sabine C Linn

PI3K pathway protein analyses in metastatic breast cancer patients receiving standard everolimus and exemestane.

Journal of cancer research and clinical oncology

Avec: Dinja T Kruger , Mark Opdam , Vincent van der Noort , Joyce Sanders , Michiel Nieuwenhuis , Bart de Valk , Karin J Beelen , Sabine C Linn , Epie Boven

Deep learning-based breast cancer grading and survival analysis on whole-slide histopathology images.

Scientific reports

Avec: Suzanne C Wetstein , Vincent M T de Jong , Nikolas Stathonikos , Mark Opdam , Gwen M H E Dackus , Josien P W Pluim , Paul J van Diest , Mitko Veta

Preferences of Patients With Musculoskeletal Disorders Regarding the Timing and Channel of eHealth and Factors Influencing Its Use: Mixed Methods Study.

JMIR human factors

Avec: Jeffrey van der Ven , Bart J F van den Bemt , Liset van Dijk , Merel Opdam , Lex L Haegens , Johanna E Vriezekolk , Lise M Verhoef

MYC is a clinically significant driver of mTOR inhibitor resistance in breast cancer.

The Journal of experimental medicine

Avec: Jinhyuk Bhin , Julia Yemelyanenko , Xue Chao , Sjoerd Klarenbeek , Mark Opdam , Yuval Malka , Liesbeth Hoekman , Dinja Kruger , Onno Bleijerveld , Chiara S Brambillasca , Justin Sprengers , Bjørn Siteur , Stefano Annunziato , Matthijs J van Haren , Nathaniel I Martin , Marieke van de Ven , Dennis Peters , Reuven Agami , Sabine C Linn , Epie Boven , Maarten Altelaar , Jos Jonkers , Daniel Zingg , Lodewyk F A Wessels

Cancer-immune interactions in ER-positive breast cancers: PI3K pathway alterations and tumor-infiltrating lymphocytes.

Breast cancer research : BCR

Avec: Marcelo Sobral-Leite , Izhar Salomon , Mark Opdam , Dinja T Kruger , Karin J Beelen , Vincent van der Noort , Ronald L P van Vlierberghe , Erik J Blok , Daniele Giardiello , Joyce Sanders , Koen Van de Vijver , Hugo M Horlings , Peter J K Kuppen , Sabine C Linn , Marjanka K Schmidt , Marleen Kok

EZH2 Is Overexpressed in

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Julian Puppe , Mark Opdam , Philip C Schouten , Katarzyna Jóźwiak , Esther Lips , Tesa Severson , Marieke van de Ven , Chiara Brambillasca , Peter Bouwman , Olaf van Tellingen , René Bernards , Jelle Wesseling , Christian Eichler , Fabinshy Thangarajah , Wolfram Malter , Gaurav Kumar Pandey , Luka Ozretić , Carlos Caldas , Maarten van Lohuizen , Michael Hauptmann , Kerstin Rhiem , Eric Hahnen , H Christian Reinhardt , Reinhard Büttner , Peter Mallmann , Birgid Schömig-Markiefka , Rita Schmutzler , Sabine Linn , Jos Jonkers

Endonuclease FEN1 Coregulates ERα Activity and Provides a Novel Drug Interface in Tamoxifen-Resistant Breast Cancer.

Cancer research

Avec: Koen D Flach , Manikandan Periyasamy , Ajit Jadhav , Dorjbal Dorjsuren , Joseph C Siefert , Theresa E Hickey , Mark Opdam , Hetal Patel , Sander Canisius , David M Wilson , Maria Donaldson Collier , Stefan Prekovic , Marja Nieuwland , Roelof J C Kluin , Alexey V Zakharov , Jelle Wesseling , Lodewyk F A Wessels , Sabine C Linn , Wayne D Tilley , Anton Simeonov , Simak Ali , Wilbert Zwart

FER regulates endosomal recycling and is a predictor for adjuvant taxane benefit in breast cancer.

Cell reports

Avec: Sandra Tavares , Nalan Liv , Milena Pasolli , Mark Opdam , Max A K Rätze , Manuel Saornil , Lilian M Sluimer , Rutger C C Hengeveld , Robert van Es , Erik van Werkhoven , Harmjan Vos , Holger Rehmann , Boudewijn M T Burgering , Hendrika M Oosterkamp , Susanne M A Lens , Judith Klumperman , Sabine C Linn , Patrick W B Derksen

Limiting systemic endocrine overtreatment in postmenopausal breast cancer patients with an ultralow classification of the 70-gene signature.

Breast cancer research and treatment

Avec: M Opdam , V van der Noort , M Kleijn , A Glas , I Mandjes , S Kleiterp , F S Hilbers , D T Kruger , A D Bins , P C de Jong , P P J B M Schiphorst , T van Dalen , B Flameling , R C Rietbroek , A Beeker , S M van den Heiligenberg , S D Bakker , A N M Wymenga , I M Oving , R M Bijlsma , P J van Diest , J B Vermorken , H van Tinteren , S C Linn

Long-term outcomes of young, node-negative, chemotherapy-naïve, triple-negative breast cancer patients according to BRCA1 status.

BMC medicine

Avec: Yuwei Wang , Gwen M H E Dackus , Efraim H Rosenberg , Sten Cornelissen , Leonora W de Boo , Annegien Broeks , Wim Brugman , Terry W S Chan , Paul J van Diest , Michael Hauptmann , Natalie D Ter Hoeve , Olga I Isaeva , Vincent M T de Jong , Katarzyna Jóźwiak , Roelof J C Kluin , Marleen Kok , Esther Koop , Petra M Nederlof , Mark Opdam , Philip C Schouten , Sabine Siesling , Charlaine van Steenis , Adri C Voogd , Willem Vreuls , Roberto F Salgado , Sabine C Linn , Marjanka K Schmidt

Multiscale deep learning framework captures systemic immune features in lymph nodes predictive of triple negative breast cancer outcome in large-scale studies.

The Journal of pathology

Avec: Gregory Verghese , Mengyuan Li , Fangfang Liu , Amit Lohan , Nikhil Cherian Kurian , Swati Meena , Patrycja Gazinska , Aekta Shah , Aasiyah Oozeer , Terry Chan , Mark Opdam , Sabine Linn , Cheryl Gillett , Elena Alberts , Thomas Hardiman , Samantha Jones , Selvam Thavaraj , J Louise Jones , Roberto Salgado , Sarah E Pinder , Swapnil Rane , Amit Sethi , Anita Grigoriadis

External validation and clinical utility assessment of PREDICT breast cancer prognostic model in young, systemic treatment-naïve women with node-negative breast cancer.

European journal of cancer (Oxford, England : 1990)

Avec: Yuwei Wang , Annegien Broeks , Daniele Giardiello , Michael Hauptmann , Katarzyna Jóźwiak , Esther A Koop , Mark Opdam , Sabine Siesling , Gabe S Sonke , Nikolas Stathonikos , Natalie D Ter Hoeve , Elsken van der Wall , Carolien H M van Deurzen , Paul J van Diest , Adri C Voogd , Willem Vreuls , Sabine C Linn , Gwen M H E Dackus , Marjanka K Schmidt

Adjuvant capecitabine-containing chemotherapy benefit and homologous recombination deficiency in early-stage triple-negative breast cancer patients.

British journal of cancer

Avec: Leonora W de Boo , Katarzyna Jóźwiak , Heikki Joensuu , Henrik Lindman , Susanna Lauttia , Mark Opdam , Charlaine van Steenis , Wim Brugman , Roelof J C Kluin , Philip C Schouten , Marleen Kok , Petra M Nederlof , Michael Hauptmann , Sabine C Linn

Prognostic Value of Stromal Tumor-Infiltrating Lymphocytes in Young, Node-Negative, Triple-Negative Breast Cancer Patients Who Did Not Receive (neo)Adjuvant Systemic Therapy.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Avec: Vincent M T de Jong , Yuwei Wang , Natalie D Ter Hoeve , Mark Opdam , Nikolas Stathonikos , Katarzyna Jóźwiak , Michael Hauptmann , Sten Cornelissen , Willem Vreuls , Efraim H Rosenberg , Esther A Koop , Zsuzsanna Varga , Carolien H M van Deurzen , Antien L Mooyaart , Alicia Córdoba , Emma J Groen , Joost Bart , Stefan M Willems , Vasiliki Zolota , Jelle Wesseling , Anna Sapino , Ewa Chmielik , Ales Ryska , Annegien Broeks , Adri C Voogd , Sherene Loi , Stefan Michiels , Gabe S Sonke , Elsken van der Wall , Sabine Siesling , Paul J van Diest , Marjanka K Schmidt , Marleen Kok , Gwen M H E Dackus , Roberto Salgado , Sabine C Linn

Effect of HIPEC according to HRD/BRCAwt genomic profile in stage III ovarian cancer: Results from the phase III OVHIPEC trial.

International journal of cancer

Avec: Simone N Koole , Philip C Schouten , Jan Hauke , Roel J C Kluin , Petra Nederlof , Lisa K Richters , Gabriele Krebsbach , Karolina Sikorska , Maartje Alkemade , Mark Opdam , Jules H Schagen van Leeuwen , Henk W R Schreuder , Ralph H M Hermans , Ignace H J T de Hingh , Constantijne H Mom , Henriette J G Arts , Maaike van Ham , Peter van Dam , Peter Vuylsteke , Joyce Sanders , Hugo M Horlings , Koen K van de Vijver , Eric Hahnen , Willemien J van Driel , Rita Schmutzler , Gabe S Sonke , Sabine C Linn

Réseau de co-auteurs

Mark Opdam 17 collaborations

Sabine C Linn 13 collaborations

Philip C Schouten 5 collaborations

Jelle Wesseling 5 collaborations

Marleen Kok 5 collaborations

Katarzyna Jóźwiak 5 collaborations

Michael Hauptmann 5 collaborations

Lodewyk F A Wessels 4 collaborations

Joyce Sanders 4 collaborations

Gwen M H E Dackus 4 collaborations

Paul J van Diest 4 collaborations

Marjanka K Schmidt 4 collaborations

Jos Jonkers 3 collaborations

Hugo M Horlings 3 collaborations

Dinja T Kruger 3 collaborations

Vincent van der Noort 3 collaborations

Epie Boven 3 collaborations

Vincent M T de Jong 3 collaborations

Nikolas Stathonikos 3 collaborations

Roelof J C Kluin 3 collaborations

Yuwei Wang 3 collaborations

Annegien Broeks 3 collaborations

Natalie D Ter Hoeve 3 collaborations

Sabine Siesling 3 collaborations

Adri C Voogd 3 collaborations

Willem Vreuls 3 collaborations

Gabe S Sonke 3 collaborations

Sjoerd Klarenbeek 2 collaborations

Jinhyuk Bhin 2 collaborations

Daniel Zingg 2 collaborations

Julia Yemelyanenko 2 collaborations

Erik van Werkhoven 2 collaborations

Sander Canisius 2 collaborations

Hendrika M Oosterkamp 2 collaborations

Lise M Verhoef 2 collaborations

Merel Opdam 2 collaborations

Koen D Flach 2 collaborations

Simak Ali 2 collaborations

Wilbert Zwart 2 collaborations

Karin J Beelen 2 collaborations

Marieke van de Ven 2 collaborations

Daniele Giardiello 2 collaborations

Eric Hahnen 2 collaborations

Rita Schmutzler 2 collaborations

Sabine Linn 2 collaborations

Efraim H Rosenberg 2 collaborations

Sten Cornelissen 2 collaborations

Leonora W de Boo 2 collaborations

Wim Brugman 2 collaborations

Petra M Nederlof 2 collaborations

Charlaine van Steenis 2 collaborations

Roberto Salgado 2 collaborations

Esther A Koop 2 collaborations

Elsken van der Wall 2 collaborations

Carolien H M van Deurzen 2 collaborations

Chris W Doornebal 1 collaboration

Sjors M Kas 1 collaboration

Nicola Bonzanni 1 collaboration

Tanya M Braumuller 1 collaboration

Ingrid van der Heijden 1 collaboration

Kelly Kersten 1 collaboration

Roebi de Bruijn 1 collaboration

Karin E de Visser 1 collaboration

Lennart Kester 1 collaboration

Danielle Seinstra 1 collaboration

Annelot G J van Rossum 1 collaboration

Claire Vennin 1 collaboration

Marlous Hoogstraat 1 collaboration

Daphne van der Velden 1 collaboration

Kerstin Hahn 1 collaboration

Iris Nederlof 1 collaboration

Ester H Lips 1 collaboration

Ingrid A M Mandjes 1 collaboration

A Elise van Leeuwen-Stok 1 collaboration

Harm van Tinteren 1 collaboration

Alex L T Imholz 1 collaboration

Johanneke E A Portielje 1 collaboration

Monique E M M Bos 1 collaboration

Sandra D Bakker 1 collaboration

Emiel J Rutgers 1 collaboration

Emile E Voest 1 collaboration

Alexander van Oudenaarden 1 collaboration

Jacco van Rheenen 1 collaboration

Frouwke Veenstra 1 collaboration

Alfons A den Broeder 1 collaboration

Wing-Yee Kwok 1 collaboration

Inger L Meek 1 collaboration

Cornelia H M van den Ende 1 collaboration

Marcel Flendrie 1 collaboration

Noortje van Herwaarden 1 collaboration

Zsolt Szijgyarto 1 collaboration

Carlo Palmieri 1 collaboration

Judith M Bliss 1 collaboration

Maggie Chon U Cheang 1 collaboration

R Charles Coombes 1 collaboration

Michiel Nieuwenhuis 1 collaboration

Bart de Valk 1 collaboration

Suzanne C Wetstein 1 collaboration

Josien P W Pluim 1 collaboration

Mitko Veta 1 collaboration

Jeffrey van der Ven 1 collaboration

Bart J F van den Bemt 1 collaboration

Liset van Dijk 1 collaboration

Lex L Haegens 1 collaboration

Johanna E Vriezekolk 1 collaboration

Xue Chao 1 collaboration

Yuval Malka 1 collaboration

Liesbeth Hoekman 1 collaboration

Dinja Kruger 1 collaboration

Onno Bleijerveld 1 collaboration

Chiara S Brambillasca 1 collaboration

Justin Sprengers 1 collaboration

Bjørn Siteur 1 collaboration

Stefano Annunziato 1 collaboration

Matthijs J van Haren 1 collaboration

Nathaniel I Martin 1 collaboration

Dennis Peters 1 collaboration

Reuven Agami 1 collaboration

Maarten Altelaar 1 collaboration

Marcelo Sobral-Leite 1 collaboration

Izhar Salomon 1 collaboration

Ronald L P van Vlierberghe 1 collaboration

Erik J Blok 1 collaboration

Koen Van de Vijver 1 collaboration

Peter J K Kuppen 1 collaboration

Julian Puppe 1 collaboration

Esther Lips 1 collaboration

Tesa Severson 1 collaboration

Chiara Brambillasca 1 collaboration

Peter Bouwman 1 collaboration

Olaf van Tellingen 1 collaboration

René Bernards 1 collaboration

Christian Eichler 1 collaboration

Fabinshy Thangarajah 1 collaboration

Wolfram Malter 1 collaboration

Gaurav Kumar Pandey 1 collaboration

Luka Ozretić 1 collaboration

Carlos Caldas 1 collaboration

Maarten van Lohuizen 1 collaboration

Kerstin Rhiem 1 collaboration

H Christian Reinhardt 1 collaboration

Reinhard Büttner 1 collaboration

Peter Mallmann 1 collaboration

Birgid Schömig-Markiefka 1 collaboration

Manikandan Periyasamy 1 collaboration

Ajit Jadhav 1 collaboration

Dorjbal Dorjsuren 1 collaboration

Joseph C Siefert 1 collaboration

Theresa E Hickey 1 collaboration

Hetal Patel 1 collaboration

David M Wilson 1 collaboration

Maria Donaldson Collier 1 collaboration

Stefan Prekovic 1 collaboration

Marja Nieuwland 1 collaboration

Alexey V Zakharov 1 collaboration

Wayne D Tilley 1 collaboration

Anton Simeonov 1 collaboration

Sandra Tavares 1 collaboration

Nalan Liv 1 collaboration

Milena Pasolli 1 collaboration

Max A K Rätze 1 collaboration

Manuel Saornil 1 collaboration

Lilian M Sluimer 1 collaboration

Rutger C C Hengeveld 1 collaboration

Robert van Es 1 collaboration

Harmjan Vos 1 collaboration

Holger Rehmann 1 collaboration

Boudewijn M T Burgering 1 collaboration

Susanne M A Lens 1 collaboration

Judith Klumperman 1 collaboration

Patrick W B Derksen 1 collaboration

V van der Noort 1 collaboration

M Kleijn 1 collaboration

A Glas 1 collaboration

I Mandjes 1 collaboration

S Kleiterp 1 collaboration

F S Hilbers 1 collaboration

D T Kruger 1 collaboration

A D Bins 1 collaboration

P C de Jong 1 collaboration

P P J B M Schiphorst 1 collaboration

T van Dalen 1 collaboration

B Flameling 1 collaboration

R C Rietbroek 1 collaboration

A Beeker 1 collaboration

S M van den Heiligenberg 1 collaboration

S D Bakker 1 collaboration

A N M Wymenga 1 collaboration

I M Oving 1 collaboration

R M Bijlsma 1 collaboration

P J van Diest 1 collaboration

J B Vermorken 1 collaboration

H van Tinteren 1 collaboration

S C Linn 1 collaboration

Terry W S Chan 1 collaboration

Olga I Isaeva 1 collaboration

Esther Koop 1 collaboration

Roberto F Salgado 1 collaboration

Gregory Verghese 1 collaboration

Mengyuan Li 1 collaboration

Fangfang Liu 1 collaboration

Amit Lohan 1 collaboration

Nikhil Cherian Kurian 1 collaboration

Swati Meena 1 collaboration

Patrycja Gazinska 1 collaboration

Aekta Shah 1 collaboration

Aasiyah Oozeer 1 collaboration

Terry Chan 1 collaboration

Cheryl Gillett 1 collaboration

Elena Alberts 1 collaboration

Thomas Hardiman 1 collaboration

Samantha Jones 1 collaboration

Selvam Thavaraj 1 collaboration

J Louise Jones 1 collaboration

Sarah E Pinder 1 collaboration

Swapnil Rane 1 collaboration

Amit Sethi 1 collaboration

Anita Grigoriadis 1 collaboration

Heikki Joensuu 1 collaboration

Henrik Lindman 1 collaboration

Susanna Lauttia 1 collaboration

Zsuzsanna Varga 1 collaboration

Antien L Mooyaart 1 collaboration

Alicia Córdoba 1 collaboration

Emma J Groen 1 collaboration

Joost Bart 1 collaboration

Stefan M Willems 1 collaboration

Vasiliki Zolota 1 collaboration

Anna Sapino 1 collaboration

Ewa Chmielik 1 collaboration

Ales Ryska 1 collaboration

Sherene Loi 1 collaboration

Stefan Michiels 1 collaboration

Simone N Koole 1 collaboration

Jan Hauke 1 collaboration

Roel J C Kluin 1 collaboration

Petra Nederlof 1 collaboration

Lisa K Richters 1 collaboration

Gabriele Krebsbach 1 collaboration

Karolina Sikorska 1 collaboration

Maartje Alkemade 1 collaboration

Jules H Schagen van Leeuwen 1 collaboration

Henk W R Schreuder 1 collaboration

Ralph H M Hermans 1 collaboration

Ignace H J T de Hingh 1 collaboration

Constantijne H Mom 1 collaboration

Henriette J G Arts 1 collaboration

Maaike van Ham 1 collaboration

Peter van Dam 1 collaboration

Peter Vuylsteke 1 collaboration

Koen K van de Vijver 1 collaboration

Willemien J van Driel 1 collaboration