M Pravenec

Affiliations

Institute of Physiology of the Czech Academy of Sciences, Prague, Czech Republic. michal.pravenec@fgu.cas.cz, josef.houstek@fgu.cas.cz.

Publications (33)

Correction: Targeting of the Plzf Gene in the Rat by Transcription Activator-Like Effector Nuclease Results in Caudal Regression Syndrome in Spontaneously Hypertensive Rats.

PloS one

Avec: František Liška , Renata Peterková , Miroslav Peterka , Vladimír Landa , Václav Zídek , Petr Mlejnek , Jan Šilhavý , Miroslava Šimáková , Vladimír Křen , Colby G Starker , Daniel F Voytas , Zsuzsanna Izsvák , Michal Pravenec

Author Correction: WWP2 regulates pathological cardiac fibrosis by modulating SMAD2 signaling.

Nature communications

Avec: Huimei Chen , Aida Moreno-Moral , Francesco Pesce , Nithya Devapragash , Massimiliano Mancini , Ee Ling Heng , Maxime Rotival , Prashant K Srivastava , Nathan Harmston , Kirill Shkura , Owen J L Rackham , Wei-Ping Yu , Xi-Ming Sun , Nicole Gui Zhen Tee , Elisabeth Li Sa Tan , Paul J R Barton , Leanne E Felkin , Enrique Lara-Pezzi , Gianni Angelini , Cristina Beltrami , Michal Pravenec , Sebastian Schafer , Leonardo Bottolo , Norbert Hubner , Costanza Emanueli , Stuart A Cook , Enrico Petretto

Changing views on the common physiologic abnormality that mediates salt sensitivity and initiation of salt-induced hypertension: Japanese research underpinning the vasodysfunction theory of salt sensitivity.

Hypertension research : official journal of the Japanese Society of Hypertension

Avec: Theodore W Kurtz , Stephen E DiCarlo , Michal Pravenec , R Curtis Morris

Systems genetics in the rat HXB/BXH family identifies Tti2 as a pleiotropic quantitative trait gene for adult hippocampal neurogenesis and serum glucose.

PLoS genetics

Avec: Anna N Senko , Rupert W Overall , Jan Silhavy , Petr Mlejnek , Hana Malínská , Martina Hüttl , Irena Marková , Klaus S Fabel , Lu Lu , Ales Stuchlik , Robert W Williams , Michal Pravenec , Gerd Kempermann

Nestin expression in intact and hypertrophic myocardium of spontaneously hypertensive rats during aging.

Journal of muscle research and cell motility

Avec: Dana Cizkova , Jitka M Zurmanova , Lucie Gerykova , Alexandros Kouvelas , Mario Heles , Barbara Elsnicova , Frantisek Galatik , Jan Silhavy , Michal Pravenec , Jaroslav Mokry

Transgenic overexpression of glutathione S-transferase μ-type 1 reduces hypertension and oxidative stress in the stroke-prone spontaneously hypertensive rat.

Journal of hypertension

Avec: Erin Olson , Michal Pravenec , Vladimir Landa , H H Caline Koh-Tan , Anna F Dominiczak , Martin W McBride , Delyth Graham

Downregulation of the

Antioxidants (Basel, Switzerland)

Avec: Jan Šilhavý , Hana Malínská , Martina Hüttl , Irena Marková , Olena Oliyarnyk , Petr Mlejnek , Miroslava Šimáková , František Liška , Ludmila Kazdová , Radka Moravcová , Jiří Novotný , Michal Pravenec

A trans locus causes a ribosomopathy in hypertrophic hearts that affects mRNA translation in a protein length-dependent fashion.

Genome biology

Avec: Franziska Witte , Jorge Ruiz-Orera , Camilla Ciolli Mattioli , Susanne Blachut , Eleonora Adami , Jana Felicitas Schulz , Valentin Schneider-Lunitz , Oliver Hummel , Giannino Patone , Michael Benedikt Mücke , Jan Šilhavý , Matthias Heinig , Leonardo Bottolo , Daniel Sanchis , Martin Vingron , Marina Chekulaeva , Michal Pravenec , Norbert Hubner , Sebastiaan van Heesch

Sodium Accumulation and Blood Capillary Rarefaction in the Skin Predispose Spontaneously Hypertensive Rats to Salt Sensitive Hypertension.

Biomedicines

Avec: Jan Šilhavý , Petr Mlejnek , Miroslava Šimáková , František Liška , Jan Kubovčiak , Eva Sticová , Michal Pravenec

Conplastic strains for identification of retrograde effects of mitochondrial dna variation on cardiometabolic traits in the spontaneously hypertensive rat.

Physiological research

Avec: M Pravenec , J Šilhavý , P Mlejnek , M Šimáková , T Mráček , A Pecinová , K Tauchmannová , M Hütl , H Malínská , L Kazdová , J Neckář , F Kolář , J Žurmanová , J Novotný , J Houštěk

Hypertension in Primary Aldosteronism Is Initiated by Salt-Induced Increases in Vascular Resistance With Reductions in Cardiac Output.

Hypertension (Dallas, Tex. : 1979)

Avec: Theodore W Kurtz , R Curtis Morris , Michal Pravenec , Heidi L Lujan , Stephen E DiCarlo

WWP2 regulates pathological cardiac fibrosis by modulating SMAD2 signaling.

Nature communications

Spontaneous nonsense mutation in

Physiological genomics

Avec: Jan Silhavy , Petr Mlejnek , Miroslava Simakova , Frantisek Liska , Hana Malinska , Irena Markova , Martina Huttl , Denisa Miklankova , Dita Musalkova , Viktor Stranecky , Stanislav Kmoch , Eva Sticova , Marek Vrbacky , Tomas Mracek , Michal Pravenec

CD36 regulates substrates utilisation in brown adipose tissue of spontaneously hypertensive rats: In vitro study.

PloS one

Avec: Jan Silhavy , Petr Mlejnek , Miroslava Šimáková , Irena Marková , Hana Malínská , Martina Hüttl , Ludmila Kazdová , Dmitry Kazantsev , Massimiliano Mancini , Jiří Novotný , Michal Pravenec

Hypolipidemic Effects of Beetroot Juice in SHR-CRP and HHTg Rat Models of Metabolic Syndrome: Analysis of Hepatic Proteome.

Metabolites

Avec: Jan Šilhavý , Petr Mlejnek , Miroslava Šimáková , Hana Malínská , Irena Marková , Martina Hüttl , Denisa Miklánková , Ludmila Kazdová , Marek Vrbacký , Alena Pecinová , Tomáš Mráček , Michal Pravenec

Pangenome reconstruction in rats enhances genotype-phenotype mapping and novel variant discovery.

bioRxiv : the preprint server for biology

Avec: Flavia Villani , Andrea Guarracino , Rachel R Ward , Tomomi Green , Madeleine Emms , Michal Pravenec , Pjotr Prins , Erik Garrison , Robert W Williams , Hao Chen , Vincenza Colonna

A revamped rat reference genome improves the discovery of genetic diversity in laboratory rats.

Cell genomics

Avec: Tristan V de Jong , Yanchao Pan , Pasi Rastas , Daniel Munro , Monika Tutaj , Huda Akil , Chris Benner , Denghui Chen , Apurva S Chitre , William Chow , Vincenza Colonna , Clifton L Dalgard , Wendy M Demos , Peter A Doris , Erik Garrison , Aron M Geurts , Hakan M Gunturkun , Victor Guryev , Thibaut Hourlier , Kerstin Howe , Jun Huang , Ted Kalbfleisch , Panjun Kim , Ling Li , Spencer Mahaffey , Fergal J Martin , Pejman Mohammadi , Ayse Bilge Ozel , Oksana Polesskaya , Michal Pravenec , Pjotr Prins , Jonathan Sebat , Jennifer R Smith , Leah C Solberg Woods , Boris Tabakoff , Alan Tracey , Marcela Uliano-Silva , Flavia Villani , Hongyang Wang , Burt M Sharp , Francesca Telese , Zhihua Jiang , Laura Saba , Xusheng Wang , Terence D Murphy , Abraham A Palmer , Anne E Kwitek , Melinda R Dwinell , Robert W Williams , Jun Z Li , Hao Chen

Small Amounts of Inorganic Nitrate or Beetroot Provide Substantial Protection From Salt-Induced Increases in Blood Pressure.

Hypertension (Dallas, Tex. : 1979)

Avec: R Curtis Morris , Michal Pravenec , Jan Šilhavý , Stephen E DiCarlo , Theodore W Kurtz

Ethnicity-Specific Skeletal Muscle Transcriptional Signatures and Their Relevance to Insulin Resistance in Singapore.

The Journal of clinical endocrinology and metabolism

Avec: Amelia Li Min Tan , Sarah R Langley , Chee Fan Tan , Jin Fang Chai , Chin Meng Khoo , Melvin Khee-Shing Leow , Eric Yin Hao Khoo , Aida Moreno-Moral , Michal Pravenec , Maxime Rotival , Suresh Anand Sadananthan , S Sendhil Velan , Kavita Venkataraman , Yap Seng Chong , Yung Seng Lee , Xueling Sim , Walter Stunkel , Mei Hui Liu , E Shyong Tai , Enrico Petretto

Hepatic Transcriptome Profiling Reveals Lack of

Nutrients

Avec: Kristýna Junková , Lukáš F Mirchi , Blanka Chylíková , Michaela Janků , Jan Šilhavý , Martina Hüttl , Irena Marková , Denisa Miklánková , Josef Včelák , Hana Malínská , Michal Pravenec , Ondřej Šeda , František Liška

Cap analysis of gene expression reveals alternative promoter usage in a rat model of hypertension.

Life science alliance

Avec: Sonal Dahale , Jorge Ruiz-Orera , Jan Silhavy , Norbert Hübner , Sebastiaan van Heesch , Michal Pravenec , Santosh S Atanur

Mechanism-based strategies to prevent salt sensitivity and salt-induced hypertension.

Clinical science (London, England : 1979)

Avec: Theodore W Kurtz , Michal Pravenec , Stephen E DiCarlo

Hemodynamic Mechanisms Initiating Salt-Sensitive Hypertension in Rat Model of Primary Aldosteronism.

Physiological research

Avec: M Pravenec , P Mlejnek , M Šimáková , J Šilhavý

Haplotype variability in mitochondrial rRNA predisposes to metabolic syndrome.

Communications biology

Avec: Petr Pecina , Kristýna Čunátová , Vilma Kaplanová , Guillermo Puertas-Frias , Jan Šilhavý , Kateřina Tauchmannová , Marek Vrbacký , Tomáš Čajka , Ondřej Gahura , Markéta Hlaváčková , Viktor Stránecký , Stanislav Kmoch , Michal Pravenec , Josef Houštěk , Tomáš Mráček , Alena Pecinová

Rat PRDM9 shapes recombination landscapes, duration of meiosis, gametogenesis, and age of fertility.

BMC biology

Avec: Ondrej Mihola , Vladimir Landa , Florencia Pratto , Kevin Brick , Tatyana Kobets , Fitore Kusari , Srdjan Gasic , Fatima Smagulova , Corinne Grey , Petr Flachs , Vaclav Gergelits , Karel Tresnak , Jan Silhavy , Petr Mlejnek , R Daniel Camerini-Otero , Michal Pravenec , Galina V Petukhova , Zdenek Trachtulec

No evidence of racial disparities in blood pressure salt sensitivity when potassium intake exceeds levels recommended in the US dietary guidelines.

American journal of physiology. Heart and circulatory physiology

Avec: Theodore W Kurtz , Stephen E DiCarlo , Michal Pravenec , R Curtis Morris

Excess ischemic tachyarrhythmias trigger protection against myocardial infarction in hypertensive rats.

Clinical science (London, England : 1979)

Avec: Jan Neckář , Petra Alánová , Veronika Olejníčková , František Papoušek , Lucie Hejnová , Jan Šilhavý , Michal Behuliak , Michal Bencze , Jaroslav Hrdlička , Marek Vecka , Dagmar Jarkovská , Jitka Švíglerová , Eliška Mistrová , Milan Štengl , Jiří Novotný , Bohuslav Ošťádal , Michal Pravenec , František Kolář

High cysteine diet reduces insulin resistance in SHR-CRP rats.

Physiological research

Avec: J Krijt , J Sokolová , J Šilhavý , P Mlejnek , J Kubovčiak , F Liška , H Malínská , M Hüttl , I Marková , M Křížková , M H Stipanuk , T Křížek , T Ditroi , P Nagy , V Kožich , M Pravenec

Genetic Complementation of ATP Synthase Deficiency Due to Dysfunction of TMEM70 Assembly Factor in Rat.

Biomedicines

Avec: Aleksandra Marković , Kateřina Tauchmannová , Miroslava Šimáková , Petr Mlejnek , Vilma Kaplanová , Petr Pecina , Alena Pecinová , František Papoušek , František Liška , Jan Šilhavý , Jana Mikešová , Jan Neckář , Josef Houštěk , Michal Pravenec , Tomáš Mráček

Beyond Genes: Inclusion of Alternative Splicing and Alternative Polyadenylation to Assess the Genetic Architecture of Predisposition to Voluntary Alcohol Consumption in Brain of the HXB/BXH Recombinant Inbred Rat Panel.

Frontiers in genetics

Avec: Ryan Lusk , Paula L Hoffman , Spencer Mahaffey , Samuel Rosean , Harry Smith , Jan Silhavy , Michal Pravenec , Boris Tabakoff , Laura M Saba

Beneficial Effects of Empagliflozin Are Mediated by Reduced Renal Inflammation and Oxidative Stress in Spontaneously Hypertensive Rats Expressing Human C-Reactive Protein.

Biomedicines

Avec: Hana Malínská , Martina Hüttl , Irena Marková , Denisa Miklánková , Silvie Hojná , František Papoušek , Jan Šilhavý , Petr Mlejnek , Josef Zicha , Jaroslav Hrdlička , Michal Pravenec , Ivana Vaněčková

A revamped rat reference genome improves the discovery of genetic diversity in laboratory rats.

bioRxiv : the preprint server for biology

Transgenic human C-reactive protein affects oxidative stress but not inflammation biomarkers in the aorta of spontaneously hypertensive rats.

BMC cardiovascular disorders

Avec: Ivana Nemeckova , Samira Eissazadeh , Jana Urbankova Rathouska , Jan Silhavy , Hana Malinska , Michal Pravenec , Petr Nachtigal

Réseau de co-auteurs

Michal Pravenec 30 collaborations

Jan Šilhavý 11 collaborations

Petr Mlejnek 10 collaborations

Jan Silhavy 8 collaborations

Miroslava Šimáková 6 collaborations

Hana Malínská 6 collaborations

Martina Hüttl 6 collaborations

Irena Marková 6 collaborations

František Liška 5 collaborations

Theodore W Kurtz 5 collaborations

Stephen E DiCarlo 5 collaborations

R Curtis Morris 4 collaborations

Robert W Williams 4 collaborations

Aida Moreno-Moral 3 collaborations

Massimiliano Mancini 3 collaborations

Maxime Rotival 3 collaborations

Leonardo Bottolo 3 collaborations

Norbert Hubner 3 collaborations

Enrico Petretto 3 collaborations

Ludmila Kazdová 3 collaborations

Jiří Novotný 3 collaborations

J Šilhavý 3 collaborations

P Mlejnek 3 collaborations

Denisa Miklánková 3 collaborations

Alena Pecinová 3 collaborations

Tomáš Mráček 3 collaborations

Flavia Villani 3 collaborations

Pjotr Prins 3 collaborations

Erik Garrison 3 collaborations

Hao Chen 3 collaborations

Vincenza Colonna 3 collaborations

Spencer Mahaffey 3 collaborations

Boris Tabakoff 3 collaborations

František Papoušek 3 collaborations

Huimei Chen 2 collaborations

Francesco Pesce 2 collaborations

Nithya Devapragash 2 collaborations

Ee Ling Heng 2 collaborations

Prashant K Srivastava 2 collaborations

Nathan Harmston 2 collaborations

Kirill Shkura 2 collaborations

Owen J L Rackham 2 collaborations

Wei-Ping Yu 2 collaborations

Xi-Ming Sun 2 collaborations

Nicole Gui Zhen Tee 2 collaborations

Elisabeth Li Sa Tan 2 collaborations

Paul J R Barton 2 collaborations

Leanne E Felkin 2 collaborations

Enrique Lara-Pezzi 2 collaborations

Gianni Angelini 2 collaborations

Cristina Beltrami 2 collaborations

Sebastian Schafer 2 collaborations

Costanza Emanueli 2 collaborations

Stuart A Cook 2 collaborations

Vladimir Landa 2 collaborations

Jorge Ruiz-Orera 2 collaborations

Sebastiaan van Heesch 2 collaborations

M Šimáková 2 collaborations

H Malínská 2 collaborations

Hana Malinska 2 collaborations

Stanislav Kmoch 2 collaborations

Marek Vrbacký 2 collaborations

Tristan V de Jong 2 collaborations

Yanchao Pan 2 collaborations

Pasi Rastas 2 collaborations

Daniel Munro 2 collaborations

Monika Tutaj 2 collaborations

Huda Akil 2 collaborations

Chris Benner 2 collaborations

Denghui Chen 2 collaborations

Apurva S Chitre 2 collaborations

William Chow 2 collaborations

Clifton L Dalgard 2 collaborations

Wendy M Demos 2 collaborations

Peter A Doris 2 collaborations

Aron M Geurts 2 collaborations

Hakan M Gunturkun 2 collaborations

Victor Guryev 2 collaborations

Thibaut Hourlier 2 collaborations

Kerstin Howe 2 collaborations

Jun Huang 2 collaborations

Ted Kalbfleisch 2 collaborations

Panjun Kim 2 collaborations

Ling Li 2 collaborations

Fergal J Martin 2 collaborations

Pejman Mohammadi 2 collaborations

Ayse Bilge Ozel 2 collaborations

Oksana Polesskaya 2 collaborations

Jonathan Sebat 2 collaborations

Jennifer R Smith 2 collaborations

Leah C Solberg Woods 2 collaborations

Alan Tracey 2 collaborations

Marcela Uliano-Silva 2 collaborations

Hongyang Wang 2 collaborations

Burt M Sharp 2 collaborations

Francesca Telese 2 collaborations

Zhihua Jiang 2 collaborations

Laura Saba 2 collaborations

Xusheng Wang 2 collaborations

Terence D Murphy 2 collaborations

Abraham A Palmer 2 collaborations

Anne E Kwitek 2 collaborations

Melinda R Dwinell 2 collaborations

Jun Z Li 2 collaborations

Petr Pecina 2 collaborations

Vilma Kaplanová 2 collaborations

Kateřina Tauchmannová 2 collaborations

Josef Houštěk 2 collaborations

Jan Neckář 2 collaborations

Jaroslav Hrdlička 2 collaborations

Renata Peterková 1 collaboration

Miroslav Peterka 1 collaboration

Vladimír Landa 1 collaboration

Václav Zídek 1 collaboration

Vladimír Křen 1 collaboration

Colby G Starker 1 collaboration

Daniel F Voytas 1 collaboration

Zsuzsanna Izsvák 1 collaboration

Anna N Senko 1 collaboration

Rupert W Overall 1 collaboration

Klaus S Fabel 1 collaboration

Lu Lu 1 collaboration

Ales Stuchlik 1 collaboration

Gerd Kempermann 1 collaboration

Dana Cizkova 1 collaboration

Jitka M Zurmanova 1 collaboration

Lucie Gerykova 1 collaboration

Alexandros Kouvelas 1 collaboration

Mario Heles 1 collaboration

Barbara Elsnicova 1 collaboration

Frantisek Galatik 1 collaboration

Jaroslav Mokry 1 collaboration

Erin Olson 1 collaboration

H H Caline Koh-Tan 1 collaboration

Anna F Dominiczak 1 collaboration

Martin W McBride 1 collaboration

Delyth Graham 1 collaboration

Olena Oliyarnyk 1 collaboration

Radka Moravcová 1 collaboration

Franziska Witte 1 collaboration

Camilla Ciolli Mattioli 1 collaboration

Susanne Blachut 1 collaboration

Eleonora Adami 1 collaboration

Jana Felicitas Schulz 1 collaboration

Valentin Schneider-Lunitz 1 collaboration

Oliver Hummel 1 collaboration

Giannino Patone 1 collaboration

Michael Benedikt Mücke 1 collaboration

Matthias Heinig 1 collaboration

Daniel Sanchis 1 collaboration

Martin Vingron 1 collaboration

Marina Chekulaeva 1 collaboration

Jan Kubovčiak 1 collaboration

Eva Sticová 1 collaboration

T Mráček 1 collaboration

A Pecinová 1 collaboration

K Tauchmannová 1 collaboration

M Hütl 1 collaboration

L Kazdová 1 collaboration

J Neckář 1 collaboration

F Kolář 1 collaboration

J Žurmanová 1 collaboration

J Novotný 1 collaboration

J Houštěk 1 collaboration

Heidi L Lujan 1 collaboration

Miroslava Simakova 1 collaboration

Frantisek Liska 1 collaboration

Irena Markova 1 collaboration

Martina Huttl 1 collaboration

Denisa Miklankova 1 collaboration

Dita Musalkova 1 collaboration

Viktor Stranecky 1 collaboration

Eva Sticova 1 collaboration

Marek Vrbacky 1 collaboration

Tomas Mracek 1 collaboration

Dmitry Kazantsev 1 collaboration

Andrea Guarracino 1 collaboration

Rachel R Ward 1 collaboration

Tomomi Green 1 collaboration

Madeleine Emms 1 collaboration

Amelia Li Min Tan 1 collaboration

Sarah R Langley 1 collaboration

Chee Fan Tan 1 collaboration

Jin Fang Chai 1 collaboration

Chin Meng Khoo 1 collaboration

Melvin Khee-Shing Leow 1 collaboration

Eric Yin Hao Khoo 1 collaboration

Suresh Anand Sadananthan 1 collaboration

S Sendhil Velan 1 collaboration

Kavita Venkataraman 1 collaboration

Yap Seng Chong 1 collaboration

Yung Seng Lee 1 collaboration

Xueling Sim 1 collaboration

Walter Stunkel 1 collaboration

Mei Hui Liu 1 collaboration

E Shyong Tai 1 collaboration

Kristýna Junková 1 collaboration

Lukáš F Mirchi 1 collaboration

Blanka Chylíková 1 collaboration

Michaela Janků 1 collaboration

Josef Včelák 1 collaboration

Ondřej Šeda 1 collaboration

Sonal Dahale 1 collaboration

Norbert Hübner 1 collaboration

Santosh S Atanur 1 collaboration

Kristýna Čunátová 1 collaboration

Guillermo Puertas-Frias 1 collaboration

Tomáš Čajka 1 collaboration

Ondřej Gahura 1 collaboration

Markéta Hlaváčková 1 collaboration

Viktor Stránecký 1 collaboration

Ondrej Mihola 1 collaboration

Florencia Pratto 1 collaboration

Kevin Brick 1 collaboration

Tatyana Kobets 1 collaboration

Fitore Kusari 1 collaboration

Srdjan Gasic 1 collaboration

Fatima Smagulova 1 collaboration

Corinne Grey 1 collaboration

Petr Flachs 1 collaboration

Vaclav Gergelits 1 collaboration

Karel Tresnak 1 collaboration

R Daniel Camerini-Otero 1 collaboration

Galina V Petukhova 1 collaboration

Zdenek Trachtulec 1 collaboration

Petra Alánová 1 collaboration

Veronika Olejníčková 1 collaboration

Lucie Hejnová 1 collaboration

Michal Behuliak 1 collaboration

Michal Bencze 1 collaboration

Marek Vecka 1 collaboration

Dagmar Jarkovská 1 collaboration

Jitka Švíglerová 1 collaboration

Eliška Mistrová 1 collaboration

Milan Štengl 1 collaboration

Bohuslav Ošťádal 1 collaboration

František Kolář 1 collaboration

J Krijt 1 collaboration

J Sokolová 1 collaboration

J Kubovčiak 1 collaboration

F Liška 1 collaboration

M Hüttl 1 collaboration

I Marková 1 collaboration

M Křížková 1 collaboration

M H Stipanuk 1 collaboration

T Křížek 1 collaboration

T Ditroi 1 collaboration

P Nagy 1 collaboration

V Kožich 1 collaboration

Aleksandra Marković 1 collaboration

Jana Mikešová 1 collaboration

Ryan Lusk 1 collaboration

Paula L Hoffman 1 collaboration

Samuel Rosean 1 collaboration

Harry Smith 1 collaboration

Laura M Saba 1 collaboration

Silvie Hojná 1 collaboration

Josef Zicha 1 collaboration

Ivana Vaněčková 1 collaboration

Ivana Nemeckova 1 collaboration

Samira Eissazadeh 1 collaboration

Jana Urbankova Rathouska 1 collaboration

Petr Nachtigal 1 collaboration