Mark Pinese

Affiliations

Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Sydney, NSW, Australia.
School of Clinical Medicine, UNSW Medicine & Health, UNSW Sydney, Sydney, NSW, Australia.

Publications (18)

Introme accurately predicts the impact of coding and noncoding variants on gene splicing, with clinical applications.

Genome biology

Avec: Patricia J Sullivan , Velimir Gayevskiy , Ryan L Davis , Marie Wong , Chelsea Mayoh , Amali Mallawaarachchi , Yvonne Hort , Mark J McCabe , Sarah Beecroft , Matilda R Jackson , Peer Arts , Andrew Dubowsky , Nigel Laing , Marcel E Dinger , Hamish S Scott , Emily Oates , Mark Pinese , Mark J Cowley

In vitro and in vivo drug screens of tumor cells identify novel therapies for high-risk child cancer.

EMBO molecular medicine

Avec: Loretta M S Lau , Chelsea Mayoh , Jinhan Xie , Paulette Barahona , Karen L MacKenzie , Marie Wong , Alvin Kamili , Maria Tsoli , Tim W Failes , Amit Kumar , Emily V A Mould , Andrew Gifford , Shu-Oi Chow , Mark Pinese , Jamie I Fletcher , Greg M Arndt , Dong-Anh Khuong-Quang , Carol Wadham , Daniel Batey , Georgina Eden , Peter Trebilcock , Swapna Joshi , Stephanie Alfred , Anjana Gopalakrishnan , Aaminah Khan , Dylan Grebert Wade , Patrick A Strong , Elodie Manouvrier , Lisa T Morgan , Miriam Span , Jin Yi Lim , Roxanne Cadiz , Caitlin Ung , David M Thomas , Katherine M Tucker , Meera Warby , Geoffrey B McCowage , Luciano Dalla-Pozza , Jennifer A Byrne , Federica Saletta , Andrew Fellowes , Stephen B Fox , Murray D Norris , Vanessa Tyrrell , Toby N Trahair , Richard B Lock , Mark J Cowley , Paul G Ekert , Michelle Haber , David S Ziegler , Glenn M Marshall

Recurrent

Cold Spring Harbor molecular case studies

Avec: Dong-Anh Khuong-Quang , Lauren M Brown , Marie Wong , Chelsea Mayoh , Alexandra Sexton-Oates , Amit Kumar , Mark Pinese , Sumanth Nagabushan , Loretta Lau , Louise E Ludlow , Andrew J Gifford , Michael Rodriguez , Jayesh Desai , Stephen B Fox , Michelle Haber , David S Ziegler , Jordan R Hansford , Glenn M Marshall , Mark J Cowley , Paul G Ekert

Whole genome, transcriptome and methylome profiling enhances actionable target discovery in high-risk pediatric cancer.

Nature medicine

Avec: Marie Wong , Chelsea Mayoh , Loretta M S Lau , Dong-Anh Khuong-Quang , Mark Pinese , Amit Kumar , Paulette Barahona , Emilie E Wilkie , Patricia Sullivan , Rachel Bowen-James , Mustafa Syed , Iñigo Martincorena , Federico Abascal , Alexandra Sherstyuk , Noemi A Bolanos , Jonathan Baber , Peter Priestley , M Emmy M Dolman , Emmy D G Fleuren , Marie-Emilie Gauthier , Emily V A Mould , Velimir Gayevskiy , Andrew J Gifford , Dylan Grebert-Wade , Patrick A Strong , Elodie Manouvrier , Meera Warby , David M Thomas , Judy Kirk , Katherine Tucker , Tracey O'Brien , Frank Alvaro , Geoffry B McCowage , Luciano Dalla-Pozza , Nicholas G Gottardo , Heather Tapp , Paul Wood , Seong-Lin Khaw , Jordan R Hansford , Andrew S Moore , Murray D Norris , Toby N Trahair , Richard B Lock , Vanessa Tyrrell , Michelle Haber , Glenn M Marshall , David S Ziegler , Paul G Ekert , Mark J Cowley

SpliceVarDB: A comprehensive database of experimentally validated human splicing variants.

American journal of human genetics

Avec: Patricia J Sullivan , Julian M W Quinn , Weilin Wu , Mark Pinese , Mark J Cowley

CAF hierarchy driven by pancreatic cancer cell p53-status creates a pro-metastatic and chemoresistant environment via perlecan.

Nature communications

Avec: Claire Vennin , Pauline Mélénec , Romain Rouet , Max Nobis , Aurélie S Cazet , Kendelle J Murphy , David Herrmann , Daniel A Reed , Morghan C Lucas , Sean C Warren , Zehra Elgundi , Mark Pinese , Gabriella Kalna , Daniel Roden , Monisha Samuel , Anaiis Zaratzian , Shane T Grey , Andrew Da Silva , Wilfred Leung , Auteur inconnu , Suresh Mathivanan , Yingxiao Wang , Anthony W Braithwaite , Daniel Christ , Ales Benda , Ashleigh Parkin , Phoebe A Phillips , John M Whitelock , Anthony J Gill , Owen J Sansom , David R Croucher , Benjamin L Parker , Marina Pajic , Jennifer P Morton , Thomas R Cox , Paul Timpson

Author Correction: Therapeutic implications of germline genetic findings in cancer.

Nature reviews. Clinical oncology

Avec: Subotheni Thavaneswaran , Emma Rath , Kathy Tucker , Anthony M Joshua , Dominique Hess , Mark Pinese , Mandy L Ballinger , David M Thomas

Precision Oncology in Surgery: Patient Selection for Operable Pancreatic Cancer.

Annals of surgery

Avec: Stephan B Dreyer , Mark Pinese , Nigel B Jamieson , Christopher J Scarlett , Emily K Colvin , Marina Pajic , Amber L Johns , Jeremy L Humphris , Jianmin Wu , Mark J Cowley , Angela Chou , Adnan M Nagrial , Lorraine Chantrill , Venessa T Chin , Marc D Jones , Kim Moran-Jones , Christopher Ross Carter , Euan J Dickson , Jaswinder S Samra , Neil D Merrett , Anthony J Gill , James G Kench , Fraser Duthie , David K Miller , Susanna Cooke , Daniela Aust , Thomas Knösel , Petra Rümmele , Robert Grützmann , Christian Pilarsky , Nam Q Nguyen , Elizabeth A Musgrove , Peter J Bailey , Colin J McKay , Andrew V Biankin , David K Chang , Auteur inconnu , Auteur inconnu

Therapeutic implications of germline genetic findings in cancer.

Nature reviews. Clinical oncology

Avec: Subotheni Thavaneswaran , Emma Rath , Kathy Tucker , Anthony M Joshua , Dominique Hess , Mark Pinese , Mandy L Ballinger , David M Thomas

Identification of novel sarcoma risk genes using a two-stage genome wide DNA sequencing strategy in cancer cluster families and population case and control cohorts.

BMC medical genetics

Avec: Rachel M Jones , Phillip E Melton , Mark Pinese , Alexander J Rea , Evan Ingley , Mandy L Ballinger , Auteur inconnu , David J Wood , David M Thomas , Eric K Moses

Parents' expectations, preferences, and recall of germline findings in a childhood cancer precision medicine trial.

Cancer

Avec: Brittany C McGill , Claire E Wakefield , Katherine M Tucker , Rebecca A Daly , Mark W Donoghoe , Janine Vetsch , Meera Warby , Noemi A Fuentes-Bolanos , Kristine Barlow-Stewart , Judy Kirk , Eliza Courtney , Tracey A O'Brien , Glenn M Marshall , Mark Pinese , Mark J Cowley , Vanessa Tyrrell , Rebecca J Deyell , David S Ziegler , Kate Hetherington

The Medical Genome Reference Bank contains whole genome and phenotype data of 2570 healthy elderly.

Nature communications

Avec: Mark Pinese , Paul Lacaze , Emma M Rath , Andrew Stone , Marie-Jo Brion , Adam Ameur , Sini Nagpal , Clare Puttick , Shane Husson , Dmitry Degrave , Tina Navin Cristina , Vivian F S Kahl , Aaron L Statham , Robyn L Woods , John J McNeil , Moeen Riaz , Margo Barr , Mark R Nelson , Christopher M Reid , Anne M Murray , Raj C Shah , Rory Wolfe , Joshua R Atkins , Chantel Fitzsimmons , Heath M Cairns , Melissa J Green , Vaughan J Carr , Mark J Cowley , Hilda A Pickett , Paul A James , Joseph E Powell , Warren Kaplan , Greg Gibson , Ulf Gyllensten , Murray J Cairns , Martin McNamara , Marcel E Dinger , David M Thomas

Translating genomic risk into an early detection strategy for sarcoma.

Genes, chromosomes & cancer

Avec: Mandy L Ballinger , Mark Pinese , David M Thomas

Genomic stratification and liquid biopsy in a rare adrenocortical carcinoma (ACC) case, with dual lung metastases.

Cold Spring Harbor molecular case studies

Avec: Mark J McCabe , Mark Pinese , Chia-Ling Chan , Nisa Sheriff , Tanya J Thompson , John Grady , Marie Wong , Marie-Emilie A Gauthier , Clare Puttick , Velimir Gayevskiy , Elektra Hajdu , Stephen Q Wong , Wade Barrett , Peter Earls , Robyn Lukeis , Yuen Y Cheng , Ruby C Y Lin , David M Thomas , D Neil Watkins , Marcel E Dinger , Ann I McCormack , Mark J Cowley

The Medical Genome Reference Bank: a whole-genome data resource of 4000 healthy elderly individuals. Rationale and cohort design.

European journal of human genetics : EJHG

Avec: Paul Lacaze , Mark Pinese , Warren Kaplan , Andrew Stone , Marie-Jo Brion , Robyn L Woods , Martin McNamara , John J McNeil , Marcel E Dinger , David M Thomas

ClinSV: clinical grade structural and copy number variant detection from whole genome sequencing data.

Genome medicine

Avec: Andre E Minoche , Ben Lundie , Greg B Peters , Thomas Ohnesorg , Mark Pinese , David M Thomas , Andreas Zankl , Tony Roscioli , Nicole Schonrock , Sarah Kummerfeld , Leslie Burnett , Marcel E Dinger , Mark J Cowley

Protocol for a comprehensive prospective cohort study of trio-based whole-genome sequencing for underlying cancer predisposition in paediatric and adolescent patients newly diagnosed with cancer: the PREDICT study.

BMJ open

Avec: Noemi Auxiliadora Fuentes Bolanos , Bhavna Padhye , Macabe Daley , Jacqueline Hunter , Kate Hetherington , Meera Warby , Eliza Courtney , Judy Kirk , Sarah Josephi-Taylor , Yuyan Chen , Frank Alvaro , Kristine Barlow-Stewart , Marie Wong-Erasmus , Paulette Barahona , Pamela Ajuyah , Ann-Kristin Altekoester , Vanessa J Tyrrell , Loretta M S Lau , Claire Wakefield , Dianne Sylvester , Katherine Tucker , Mark Pinese , Luciano Dalla Pozza , Tracey A O'Brien

Precision Medicine Is Changing the Roles of Healthcare Professionals, Scientists, and Research Staff: Learnings from a Childhood Cancer Precision Medicine Trial.

Journal of personalized medicine

Avec: Rebecca Daly , Kate Hetherington , Emily Hazell , Bethany R Wadling , Vanessa Tyrrell , Katherine M Tucker , Glenn M Marshall , David S Ziegler , Loretta M S Lau , Toby N Trahair , Tracey A O'Brien , Kiri Collins , Andrew J Gifford , Michelle Haber , Mark Pinese , David Malkin , Mark J Cowley , Jonathan Karpelowsky , Donna Drew , Chris Jacobs , Claire E Wakefield

Réseau de co-auteurs

Mark J Cowley 11 collaborations

David M Thomas 10 collaborations

Marie Wong 5 collaborations

Marcel E Dinger 5 collaborations

David S Ziegler 5 collaborations

Glenn M Marshall 5 collaborations

Chelsea Mayoh 4 collaborations

Loretta M S Lau 4 collaborations

Meera Warby 4 collaborations

Vanessa Tyrrell 4 collaborations

Michelle Haber 4 collaborations

None None 4 collaborations

Mandy L Ballinger 4 collaborations

Velimir Gayevskiy 3 collaborations

Paulette Barahona 3 collaborations

Amit Kumar 3 collaborations

Dong-Anh Khuong-Quang 3 collaborations

Katherine M Tucker 3 collaborations

Toby N Trahair 3 collaborations

Paul G Ekert 3 collaborations

Andrew J Gifford 3 collaborations

Judy Kirk 3 collaborations

Tracey A O'Brien 3 collaborations

Kate Hetherington 3 collaborations

Patricia J Sullivan 2 collaborations

Mark J McCabe 2 collaborations

Emily V A Mould 2 collaborations

Patrick A Strong 2 collaborations

Elodie Manouvrier 2 collaborations

Luciano Dalla-Pozza 2 collaborations

Stephen B Fox 2 collaborations

Murray D Norris 2 collaborations

Richard B Lock 2 collaborations

Jordan R Hansford 2 collaborations

Katherine Tucker 2 collaborations

Frank Alvaro 2 collaborations

Anthony J Gill 2 collaborations

Marina Pajic 2 collaborations

Subotheni Thavaneswaran 2 collaborations

Emma Rath 2 collaborations

Kathy Tucker 2 collaborations

Anthony M Joshua 2 collaborations

Dominique Hess 2 collaborations

Claire E Wakefield 2 collaborations

Kristine Barlow-Stewart 2 collaborations

Eliza Courtney 2 collaborations

Paul Lacaze 2 collaborations

Andrew Stone 2 collaborations

Marie-Jo Brion 2 collaborations

Clare Puttick 2 collaborations

Robyn L Woods 2 collaborations

John J McNeil 2 collaborations

Warren Kaplan 2 collaborations

Martin McNamara 2 collaborations

Ryan L Davis 1 collaboration

Amali Mallawaarachchi 1 collaboration

Yvonne Hort 1 collaboration

Sarah Beecroft 1 collaboration

Matilda R Jackson 1 collaboration

Peer Arts 1 collaboration

Andrew Dubowsky 1 collaboration

Nigel Laing 1 collaboration

Hamish S Scott 1 collaboration

Emily Oates 1 collaboration

Jinhan Xie 1 collaboration

Karen L MacKenzie 1 collaboration

Alvin Kamili 1 collaboration

Maria Tsoli 1 collaboration

Tim W Failes 1 collaboration

Andrew Gifford 1 collaboration

Shu-Oi Chow 1 collaboration

Jamie I Fletcher 1 collaboration

Greg M Arndt 1 collaboration

Carol Wadham 1 collaboration

Daniel Batey 1 collaboration

Georgina Eden 1 collaboration

Peter Trebilcock 1 collaboration

Swapna Joshi 1 collaboration

Stephanie Alfred 1 collaboration

Anjana Gopalakrishnan 1 collaboration

Aaminah Khan 1 collaboration

Dylan Grebert Wade 1 collaboration

Lisa T Morgan 1 collaboration

Miriam Span 1 collaboration

Jin Yi Lim 1 collaboration

Roxanne Cadiz 1 collaboration

Caitlin Ung 1 collaboration

Geoffrey B McCowage 1 collaboration

Jennifer A Byrne 1 collaboration

Federica Saletta 1 collaboration

Andrew Fellowes 1 collaboration

Lauren M Brown 1 collaboration

Alexandra Sexton-Oates 1 collaboration

Sumanth Nagabushan 1 collaboration

Loretta Lau 1 collaboration

Louise E Ludlow 1 collaboration

Michael Rodriguez 1 collaboration

Jayesh Desai 1 collaboration

Emilie E Wilkie 1 collaboration

Patricia Sullivan 1 collaboration

Rachel Bowen-James 1 collaboration

Mustafa Syed 1 collaboration

Iñigo Martincorena 1 collaboration

Federico Abascal 1 collaboration

Alexandra Sherstyuk 1 collaboration

Noemi A Bolanos 1 collaboration

Jonathan Baber 1 collaboration

Peter Priestley 1 collaboration

M Emmy M Dolman 1 collaboration

Emmy D G Fleuren 1 collaboration

Marie-Emilie Gauthier 1 collaboration

Dylan Grebert-Wade 1 collaboration

Tracey O'Brien 1 collaboration

Geoffry B McCowage 1 collaboration

Nicholas G Gottardo 1 collaboration

Heather Tapp 1 collaboration

Paul Wood 1 collaboration

Seong-Lin Khaw 1 collaboration

Andrew S Moore 1 collaboration

Julian M W Quinn 1 collaboration

Weilin Wu 1 collaboration

Claire Vennin 1 collaboration

Pauline Mélénec 1 collaboration

Romain Rouet 1 collaboration

Max Nobis 1 collaboration

Aurélie S Cazet 1 collaboration

Kendelle J Murphy 1 collaboration

David Herrmann 1 collaboration

Daniel A Reed 1 collaboration

Morghan C Lucas 1 collaboration

Sean C Warren 1 collaboration

Zehra Elgundi 1 collaboration

Gabriella Kalna 1 collaboration

Daniel Roden 1 collaboration

Monisha Samuel 1 collaboration

Anaiis Zaratzian 1 collaboration

Shane T Grey 1 collaboration

Andrew Da Silva 1 collaboration

Wilfred Leung 1 collaboration

Suresh Mathivanan 1 collaboration

Yingxiao Wang 1 collaboration

Anthony W Braithwaite 1 collaboration

Daniel Christ 1 collaboration

Ales Benda 1 collaboration

Ashleigh Parkin 1 collaboration

Phoebe A Phillips 1 collaboration

John M Whitelock 1 collaboration

Owen J Sansom 1 collaboration

David R Croucher 1 collaboration

Benjamin L Parker 1 collaboration

Jennifer P Morton 1 collaboration

Thomas R Cox 1 collaboration

Paul Timpson 1 collaboration

Stephan B Dreyer 1 collaboration

Nigel B Jamieson 1 collaboration

Christopher J Scarlett 1 collaboration

Emily K Colvin 1 collaboration

Amber L Johns 1 collaboration

Jeremy L Humphris 1 collaboration

Jianmin Wu 1 collaboration

Angela Chou 1 collaboration

Adnan M Nagrial 1 collaboration

Lorraine Chantrill 1 collaboration

Venessa T Chin 1 collaboration

Marc D Jones 1 collaboration

Kim Moran-Jones 1 collaboration

Christopher Ross Carter 1 collaboration

Euan J Dickson 1 collaboration

Jaswinder S Samra 1 collaboration

Neil D Merrett 1 collaboration

James G Kench 1 collaboration

Fraser Duthie 1 collaboration

David K Miller 1 collaboration

Susanna Cooke 1 collaboration

Daniela Aust 1 collaboration

Thomas Knösel 1 collaboration

Petra Rümmele 1 collaboration

Robert Grützmann 1 collaboration

Christian Pilarsky 1 collaboration

Nam Q Nguyen 1 collaboration

Elizabeth A Musgrove 1 collaboration

Peter J Bailey 1 collaboration

Colin J McKay 1 collaboration

Andrew V Biankin 1 collaboration

David K Chang 1 collaboration

Rachel M Jones 1 collaboration

Phillip E Melton 1 collaboration

Alexander J Rea 1 collaboration

Evan Ingley 1 collaboration

David J Wood 1 collaboration

Eric K Moses 1 collaboration

Brittany C McGill 1 collaboration

Rebecca A Daly 1 collaboration

Mark W Donoghoe 1 collaboration

Janine Vetsch 1 collaboration

Noemi A Fuentes-Bolanos 1 collaboration

Rebecca J Deyell 1 collaboration

Emma M Rath 1 collaboration

Adam Ameur 1 collaboration

Sini Nagpal 1 collaboration

Shane Husson 1 collaboration

Dmitry Degrave 1 collaboration

Tina Navin Cristina 1 collaboration

Vivian F S Kahl 1 collaboration

Aaron L Statham 1 collaboration

Moeen Riaz 1 collaboration

Margo Barr 1 collaboration

Mark R Nelson 1 collaboration

Christopher M Reid 1 collaboration

Anne M Murray 1 collaboration

Raj C Shah 1 collaboration

Rory Wolfe 1 collaboration

Joshua R Atkins 1 collaboration

Chantel Fitzsimmons 1 collaboration

Heath M Cairns 1 collaboration

Melissa J Green 1 collaboration

Vaughan J Carr 1 collaboration

Hilda A Pickett 1 collaboration

Paul A James 1 collaboration

Joseph E Powell 1 collaboration

Greg Gibson 1 collaboration

Ulf Gyllensten 1 collaboration

Murray J Cairns 1 collaboration

Chia-Ling Chan 1 collaboration

Nisa Sheriff 1 collaboration

Tanya J Thompson 1 collaboration

John Grady 1 collaboration

Marie-Emilie A Gauthier 1 collaboration

Elektra Hajdu 1 collaboration

Stephen Q Wong 1 collaboration

Wade Barrett 1 collaboration

Peter Earls 1 collaboration

Robyn Lukeis 1 collaboration

Yuen Y Cheng 1 collaboration

Ruby C Y Lin 1 collaboration

D Neil Watkins 1 collaboration

Ann I McCormack 1 collaboration

Andre E Minoche 1 collaboration

Ben Lundie 1 collaboration

Greg B Peters 1 collaboration

Thomas Ohnesorg 1 collaboration

Andreas Zankl 1 collaboration

Tony Roscioli 1 collaboration

Nicole Schonrock 1 collaboration

Sarah Kummerfeld 1 collaboration

Leslie Burnett 1 collaboration

Noemi Auxiliadora Fuentes Bolanos 1 collaboration

Bhavna Padhye 1 collaboration

Macabe Daley 1 collaboration

Jacqueline Hunter 1 collaboration

Sarah Josephi-Taylor 1 collaboration

Yuyan Chen 1 collaboration

Marie Wong-Erasmus 1 collaboration

Pamela Ajuyah 1 collaboration

Ann-Kristin Altekoester 1 collaboration

Vanessa J Tyrrell 1 collaboration

Claire Wakefield 1 collaboration

Dianne Sylvester 1 collaboration

Luciano Dalla Pozza 1 collaboration

Rebecca Daly 1 collaboration

Emily Hazell 1 collaboration

Bethany R Wadling 1 collaboration

Kiri Collins 1 collaboration

David Malkin 1 collaboration

Jonathan Karpelowsky 1 collaboration

Donna Drew 1 collaboration

Chris Jacobs 1 collaboration