Mathias Linnerbauer

Affiliations

Ann Romney Center for Neurologic Diseases, Harvard Medical School, Brigham and Women's Hospital, Boston, MA, USA.

ORCID: http://orcid.org/0000-0002-5528-5141

Publications (22)

Lactate limits CNS autoimmunity by stabilizing HIF-1α in dendritic cells.

Nature

Avec: Liliana M Sanmarco , Joseph M Rone , Carolina M Polonio , Gonzalo Fernandez Lahore , Federico Giovannoni , Kylynne Ferrara , Cristina Gutierrez-Vazquez , Ning Li , Anna Sokolovska , Agustin Plasencia , Camilo Faust Akl , Payal Nanda , Evelin S Heck , Zhaorong Li , Hong-Gyun Lee , Chun-Cheih Chao , Claudia M Rejano-Gordillo , Pedro H Fonseca-Castro , Tomer Illouz , Mathias Linnerbauer , Jessica E Kenison , Rocky M Barilla , Daniel Farrenkopf , Nikolas A Stevens , Gavin Piester , Elizabeth N Chung , Lucas Dailey , Vijay K Kuchroo , David Hava , Michael A Wheeler , Clary Clish , Roni Nowarski , Eduardo Balsa , Jose M Lora , Francisco J Quintana

Droplet-based functional CRISPR screening of cell-cell interactions by SPEAC-seq.

Nature protocols

Avec: Camilo Faust Akl , Mathias Linnerbauer , Zhaorong Li , Hong-Gyun Lee , Iain C Clark , Michael A Wheeler , Francisco J Quintana

IL-22 Binding Protein Promotes the Disease Process in Multiple Sclerosis.

Journal of immunology (Baltimore, Md. : 1950)

Avec: Hannes Lindahl , André O Guerreiro-Cacais , Sahl Khalid Bedri , Mathias Linnerbauer , Magdalena Lindén , Nada Abdelmagid , Karolina Tandre , Claire Hollins , Lorraine Irving , Colin Glover , Clare Jones , Lars Alfredsson , Lars Rönnblom , Ingrid Kockum , Mohsen Khademi , Maja Jagodic , Tomas Olsson

Gut-licensed IFNγ

Nature

Avec: Liliana M Sanmarco , Michael A Wheeler , Cristina Gutiérrez-Vázquez , Carolina Manganeli Polonio , Mathias Linnerbauer , Felipe A Pinho-Ribeiro , Zhaorong Li , Federico Giovannoni , Katelyn V Batterman , Giulia Scalisi , Stephanie E J Zandee , Evelyn S Heck , Moneera Alsuwailm , Douglas L Rosene , Burkhard Becher , Isaac M Chiu , Alexandre Prat , Francisco J Quintana

Protective Functions of Reactive Astrocytes Following Central Nervous System Insult.

Frontiers in immunology

Avec: Mathias Linnerbauer , Veit Rothhammer

Aryl Hydrocarbon Receptor Plasma Agonist Activity Correlates With Disease Activity in Progressive MS.

Neurology(R) neuroimmunology & neuroinflammation

Avec: Thanos Tsaktanis , Tobias Beyer , Lucy Nirschl , Mathias Linnerbauer , Verena Grummel , Mathias Bussas , Emily Tjon , Mark Mühlau , Thomas Korn , Bernhard Hemmer , Francisco J Quintana , Veit Rothhammer

Microglial expression of CD83 governs cellular activation and restrains neuroinflammation in experimental autoimmune encephalomyelitis.

Nature communications

Avec: Pia Sinner , Katrin Peckert-Maier , Hashem Mohammadian , Christine Kuhnt , Christina Draßner , Vasiliki Panagiotakopoulou , Simon Rauber , Mathias Linnerbauer , Zhana Haimon , Dmytro Royzman , Deborah Kronenberg-Versteeg , Andreas Ramming , Alexander Steinkasserer , Andreas B Wild

Cerebrospinal fluid biomarkers for cerebral amyloid angiopathy.

Brain communications

Avec: Jochen A Sembill , Christoph Lusse , Mathias Linnerbauer , Maximilian I Sprügel , Anne Mrochen , Michael Knott , Tobias Engelhorn , Manuel Alexander Schmidt , Arnd Doerfler , Timo Jan Oberstein , Juan Manuel Maler , Johannes Kornhuber , Piotr Lewczuk , Veit Rothhammer , Stefan Schwab , Joji B Kuramatsu

Gut-Brain Interactions and Their Impact on Astrocytes in the Context of Multiple Sclerosis and Beyond.

Cells

Avec: Julia Zißler , Veit Rothhammer , Mathias Linnerbauer

Astrocyte Crosstalk in CNS Inflammation.

Neuron

Avec: Mathias Linnerbauer , Michael A Wheeler , Francisco J Quintana

Barcoded viral tracing of single-cell interactions in central nervous system inflammation.

Science (New York, N.Y.)

Avec: Iain C Clark , Cristina Gutiérrez-Vázquez , Michael A Wheeler , Zhaorong Li , Veit Rothhammer , Mathias Linnerbauer , Liliana M Sanmarco , Lydia Guo , Manon Blain , Stephanie E J Zandee , Chun-Cheih Chao , Katelyn V Batterman , Marius Schwabenland , Peter Lotfy , Amalia Tejeda-Velarde , Patrick Hewson , Carolina Manganeli Polonio , Michael W Shultis , Yasmin Salem , Emily C Tjon , Pedro H Fonseca-Castro , Davis M Borucki , Kalil Alves de Lima , Agustin Plasencia , Adam R Abate , Douglas L Rosene , Kevin J Hodgetts , Marco Prinz , Jack P Antel , Alexandre Prat , Francisco J Quintana

Astrocyte-Derived Pleiotrophin Mitigates Late-Stage Autoimmune CNS Inflammation.

Frontiers in immunology

Avec: Mathias Linnerbauer , Lena Lößlein , Daniel Farrenkopf , Oliver Vandrey , Thanos Tsaktanis , Ulrike Naumann , Veit Rothhammer

Identification of environmental factors that promote intestinal inflammation.

Nature

Avec: Liliana M Sanmarco , Chun-Cheih Chao , Yu-Chao Wang , Jessica E Kenison , Zhaorong Li , Joseph M Rone , Claudia M Rejano-Gordillo , Carolina M Polonio , Cristina Gutierrez-Vazquez , Gavin Piester , Agustin Plasencia , Lucinda Li , Federico Giovannoni , Hong-Gyun Lee , Camilo Faust Akl , Michael A Wheeler , Ivan Mascanfroni , Merja Jaronen , Moneera Alsuwailm , Patrick Hewson , Ada Yeste , Brian M Andersen , Diana G Franks , Chien-Jung Huang , Millicent Ekwudo , Emily C Tjon , Veit Rothhammer , Maisa Takenaka , Kalil Alves de Lima , Mathias Linnerbauer , Lydia Guo , Ruxandra Covacu , Hugo Queva , Pedro Henrique Fonseca-Castro , Maha Al Bladi , Laura M Cox , Kevin J Hodgetts , Mark E Hahn , Alexander Mildner , Joshua Korzenik , Russ Hauser , Scott B Snapper , Francisco J Quintana

PD-L1 positive astrocytes attenuate inflammatory functions of PD-1 positive microglia in models of autoimmune neuroinflammation.

Nature communications

Avec: Mathias Linnerbauer , Tobias Beyer , Lucy Nirschl , Daniel Farrenkopf , Lena Lößlein , Oliver Vandrey , Anne Peter , Thanos Tsaktanis , Hania Kebir , David Laplaud , Rupert Oellinger , Thomas Engleitner , Jorge Ivan Alvarez , Roland Rad , Thomas Korn , Bernhard Hemmer , Francisco J Quintana , Veit Rothhammer

The Aryl Hydrocarbon Receptor-Dependent TGF-α/VEGF-B Ratio Correlates With Disease Subtype and Prognosis in Multiple Sclerosis.

Neurology(R) neuroimmunology & neuroinflammation

Avec: Ana Cirac , Thanos Tsaktanis , Tobias Beyer , Mathias Linnerbauer , Till Andlauer , Verena Grummel , Lucy Nirschl , Lena Loesslein , Francisco J Quintana , Bernhard Hemmer , Veit Rothhammer

Intranasal delivery of a small-molecule ErbB inhibitor promotes recovery from acute and late-stage CNS inflammation.

JCI insight

Avec: Mathias Linnerbauer , Lena Lößlein , Oliver Vandrey , Thanos Tsaktanis , Alexander Beer , Ulrike J Naumann , Franziska Panier , Tobias Beyer , Lucy Nirschl , Joji B Kuramatsu , Jürgen Winkler , Francisco J Quintana , Veit Rothhammer

Identification of four novel T cell autoantigens and personal autoreactive profiles in multiple sclerosis.

Science advances

Avec: Mattias Bronge , Klara Asplund Högelin , Olivia G Thomas , Sabrina Ruhrmann , Claudia Carvalho-Queiroz , Ola B Nilsson , Andreas Kaiser , Manuel Zeitelhofer , Erik Holmgren , Mathias Linnerbauer , Milena Z Adzemovic , Cecilia Hellström , Ivan Jelcic , Hao Liu , Peter Nilsson , Jan Hillert , Lou Brundin , Katharina Fink , Ingrid Kockum , Katarina Tengvall , Roland Martin , Hanna Tegel , Torbjörn Gräslund , Faiez Al Nimer , André Ortlieb Guerreiro-Cacais , Mohsen Khademi , Guro Gafvelin , Tomas Olsson , Hans Grönlund

Engineered probiotics limit CNS autoimmunity by stabilizing HIF-1α in dendritic cells.

bioRxiv : the preprint server for biology

Avec: Liliana M Sanmarco , Joseph M Rone , Carolina M Polonio , Federico Giovannoni , Gonzalo Fernandez Lahore , Kylynne Ferrara , Cristina Gutierrez-Vazquez , Ning Li , Anna Sokolovska , Agustin Plasencia , Camilo Faust Akl , Payal Nanda , Evelin S Heck , Zhaorong Li , Hong-Gyun Lee , Chun-Cheih Chao , Claudia M Rejano-Gordillo , Pedro H Fonseca-Castro , Tomer Illouz , Mathias Linnerbauer , Jessica E Kenison , Rocky M Barilla , Daniel Farrenkopf , Gavin Piester , Lucas Dailey , Vijay K Kuchroo , David Hava , Michael A Wheeler , Clary Clish , Roni Nowarski , Eduardo Balsa , Jose M Lora , Francisco J Quintana

Droplet-based forward genetic screening of astrocyte-microglia cross-talk.

Science (New York, N.Y.)

Avec: Michael A Wheeler , Iain C Clark , Hong-Gyun Lee , Zhaorong Li , Mathias Linnerbauer , Joseph M Rone , Manon Blain , Camilo Faust Akl , Gavin Piester , Federico Giovannoni , Marc Charabati , Joon-Hyuk Lee , Yoon-Chul Kye , Joshua Choi , Liliana M Sanmarco , Lena Srun , Elizabeth N Chung , Lucas E Flausino , Brian M Andersen , Veit Rothhammer , Hiroshi Yano , Tomer Illouz , Stephanie E J Zandee , Carolin Daniel , David Artis , Marco Prinz , Adam R Abate , Vijay K Kuchroo , Jack P Antel , Alexandre Prat , Francisco J Quintana

Regulation of the programmed cell death protein 1/programmed cell death ligand 1 axis in relapsing-remitting multiple sclerosis.

Brain communications

Avec: Thanos Tsaktanis , Mathias Linnerbauer , Lena Lößlein , Daniel Farrenkopf , Oliver Vandrey , Anne Peter , Ana Cirac , Tobias Beyer , Lucy Nirschl , Verena Grummel , Mark Mühlau , Matthias Bussas , Bernhard Hemmer , Francisco J Quintana , Veit Rothhammer

The role of midkine in health and disease.

Frontiers in immunology

Avec: Emely Elisa Neumaier , Veit Rothhammer , Mathias Linnerbauer

The astrocyte-produced growth factor HB-EGF limits autoimmune CNS pathology.

Nature immunology

Avec: Mathias Linnerbauer , Lena Lößlein , Oliver Vandrey , Anne Peter , Yanan Han , Thanos Tsaktanis , Emile Wogram , Maria Needhamsen , Lara Kular , Lisa Nagel , Julia Zissler , Marie Andert , Lisa Meszaros , Jannis Hanspach , Finnja Zuber , Ulrike J Naumann , Martin Diebold , Michael A Wheeler , Tobias Beyer , Lucy Nirschl , Ana Cirac , Frederik B Laun , Claudia Günther , Jürgen Winkler , Tobias Bäuerle , Maja Jagodic , Bernhard Hemmer , Marco Prinz , Francisco J Quintana , Veit Rothhammer

Réseau de co-auteurs

Francisco J Quintana 14 collaborations

Veit Rothhammer 14 collaborations

Michael A Wheeler 9 collaborations

Zhaorong Li 7 collaborations

Thanos Tsaktanis 7 collaborations

Liliana M Sanmarco 6 collaborations

Tobias Beyer 6 collaborations

Lucy Nirschl 6 collaborations

Federico Giovannoni 5 collaborations

Camilo Faust Akl 5 collaborations

Hong-Gyun Lee 5 collaborations

Daniel Farrenkopf 5 collaborations

Bernhard Hemmer 5 collaborations

Lena Lößlein 5 collaborations

Oliver Vandrey 5 collaborations

Joseph M Rone 4 collaborations

Agustin Plasencia 4 collaborations

Chun-Cheih Chao 4 collaborations

Gavin Piester 4 collaborations

Carolina M Polonio 3 collaborations

Cristina Gutierrez-Vazquez 3 collaborations

Claudia M Rejano-Gordillo 3 collaborations

Pedro H Fonseca-Castro 3 collaborations

Tomer Illouz 3 collaborations

Jessica E Kenison 3 collaborations

Vijay K Kuchroo 3 collaborations

Iain C Clark 3 collaborations

Stephanie E J Zandee 3 collaborations

Alexandre Prat 3 collaborations

Verena Grummel 3 collaborations

Marco Prinz 3 collaborations

Anne Peter 3 collaborations

Ana Cirac 3 collaborations

Gonzalo Fernandez Lahore 2 collaborations

Kylynne Ferrara 2 collaborations

Ning Li 2 collaborations

Anna Sokolovska 2 collaborations

Payal Nanda 2 collaborations

Evelin S Heck 2 collaborations

Rocky M Barilla 2 collaborations

Elizabeth N Chung 2 collaborations

Lucas Dailey 2 collaborations

David Hava 2 collaborations

Clary Clish 2 collaborations

Roni Nowarski 2 collaborations

Eduardo Balsa 2 collaborations

Jose M Lora 2 collaborations

Ingrid Kockum 2 collaborations

Mohsen Khademi 2 collaborations

Maja Jagodic 2 collaborations

Tomas Olsson 2 collaborations

Cristina Gutiérrez-Vázquez 2 collaborations

Carolina Manganeli Polonio 2 collaborations

Katelyn V Batterman 2 collaborations

Moneera Alsuwailm 2 collaborations

Douglas L Rosene 2 collaborations

Mark Mühlau 2 collaborations

Thomas Korn 2 collaborations

Joji B Kuramatsu 2 collaborations

Lydia Guo 2 collaborations

Manon Blain 2 collaborations

Patrick Hewson 2 collaborations

Emily C Tjon 2 collaborations

Kalil Alves de Lima 2 collaborations

Adam R Abate 2 collaborations

Kevin J Hodgetts 2 collaborations

Jack P Antel 2 collaborations

Brian M Andersen 2 collaborations

Ulrike J Naumann 2 collaborations

Jürgen Winkler 2 collaborations

Nikolas A Stevens 1 collaboration

Hannes Lindahl 1 collaboration

André O Guerreiro-Cacais 1 collaboration

Sahl Khalid Bedri 1 collaboration

Magdalena Lindén 1 collaboration

Nada Abdelmagid 1 collaboration

Karolina Tandre 1 collaboration

Claire Hollins 1 collaboration

Lorraine Irving 1 collaboration

Colin Glover 1 collaboration

Clare Jones 1 collaboration

Lars Alfredsson 1 collaboration

Lars Rönnblom 1 collaboration

Felipe A Pinho-Ribeiro 1 collaboration

Giulia Scalisi 1 collaboration

Evelyn S Heck 1 collaboration

Burkhard Becher 1 collaboration

Isaac M Chiu 1 collaboration

Mathias Bussas 1 collaboration

Emily Tjon 1 collaboration

Pia Sinner 1 collaboration

Katrin Peckert-Maier 1 collaboration

Hashem Mohammadian 1 collaboration

Christine Kuhnt 1 collaboration

Christina Draßner 1 collaboration

Vasiliki Panagiotakopoulou 1 collaboration

Simon Rauber 1 collaboration

Zhana Haimon 1 collaboration

Dmytro Royzman 1 collaboration

Deborah Kronenberg-Versteeg 1 collaboration

Andreas Ramming 1 collaboration

Alexander Steinkasserer 1 collaboration

Andreas B Wild 1 collaboration

Jochen A Sembill 1 collaboration

Christoph Lusse 1 collaboration

Maximilian I Sprügel 1 collaboration

Anne Mrochen 1 collaboration

Michael Knott 1 collaboration

Tobias Engelhorn 1 collaboration

Manuel Alexander Schmidt 1 collaboration

Arnd Doerfler 1 collaboration

Timo Jan Oberstein 1 collaboration

Juan Manuel Maler 1 collaboration

Johannes Kornhuber 1 collaboration

Piotr Lewczuk 1 collaboration

Stefan Schwab 1 collaboration

Julia Zißler 1 collaboration

Marius Schwabenland 1 collaboration

Peter Lotfy 1 collaboration

Amalia Tejeda-Velarde 1 collaboration

Michael W Shultis 1 collaboration

Yasmin Salem 1 collaboration

Davis M Borucki 1 collaboration

Ulrike Naumann 1 collaboration

Yu-Chao Wang 1 collaboration

Lucinda Li 1 collaboration

Ivan Mascanfroni 1 collaboration

Merja Jaronen 1 collaboration

Ada Yeste 1 collaboration

Diana G Franks 1 collaboration

Chien-Jung Huang 1 collaboration

Millicent Ekwudo 1 collaboration

Maisa Takenaka 1 collaboration

Ruxandra Covacu 1 collaboration

Hugo Queva 1 collaboration

Pedro Henrique Fonseca-Castro 1 collaboration

Maha Al Bladi 1 collaboration

Laura M Cox 1 collaboration

Mark E Hahn 1 collaboration

Alexander Mildner 1 collaboration

Joshua Korzenik 1 collaboration

Russ Hauser 1 collaboration

Scott B Snapper 1 collaboration

Hania Kebir 1 collaboration

David Laplaud 1 collaboration

Rupert Oellinger 1 collaboration

Thomas Engleitner 1 collaboration

Jorge Ivan Alvarez 1 collaboration

Roland Rad 1 collaboration

Till Andlauer 1 collaboration

Lena Loesslein 1 collaboration

Alexander Beer 1 collaboration

Franziska Panier 1 collaboration

Mattias Bronge 1 collaboration

Klara Asplund Högelin 1 collaboration

Olivia G Thomas 1 collaboration

Sabrina Ruhrmann 1 collaboration

Claudia Carvalho-Queiroz 1 collaboration

Ola B Nilsson 1 collaboration

Andreas Kaiser 1 collaboration

Manuel Zeitelhofer 1 collaboration

Erik Holmgren 1 collaboration

Milena Z Adzemovic 1 collaboration

Cecilia Hellström 1 collaboration

Ivan Jelcic 1 collaboration

Hao Liu 1 collaboration

Peter Nilsson 1 collaboration

Jan Hillert 1 collaboration

Lou Brundin 1 collaboration

Katharina Fink 1 collaboration

Katarina Tengvall 1 collaboration

Roland Martin 1 collaboration

Hanna Tegel 1 collaboration

Torbjörn Gräslund 1 collaboration

Faiez Al Nimer 1 collaboration

André Ortlieb Guerreiro-Cacais 1 collaboration

Guro Gafvelin 1 collaboration

Hans Grönlund 1 collaboration

Marc Charabati 1 collaboration

Joon-Hyuk Lee 1 collaboration

Yoon-Chul Kye 1 collaboration

Joshua Choi 1 collaboration

Lena Srun 1 collaboration

Lucas E Flausino 1 collaboration

Hiroshi Yano 1 collaboration

Carolin Daniel 1 collaboration

David Artis 1 collaboration

Matthias Bussas 1 collaboration

Emely Elisa Neumaier 1 collaboration

Yanan Han 1 collaboration

Emile Wogram 1 collaboration

Maria Needhamsen 1 collaboration

Lara Kular 1 collaboration

Lisa Nagel 1 collaboration

Julia Zissler 1 collaboration

Marie Andert 1 collaboration

Lisa Meszaros 1 collaboration

Jannis Hanspach 1 collaboration

Finnja Zuber 1 collaboration

Martin Diebold 1 collaboration

Frederik B Laun 1 collaboration

Claudia Günther 1 collaboration

Tobias Bäuerle 1 collaboration