Michelle Machacek

Affiliations

Merck & Co., Inc., Kenilworth, NJ, USA.

Publications (26)

Pharmacokinetics-Pharmacodynamics of Enmetazobactam Combined with Cefepime in a Neutropenic Murine Thigh Infection Model.

Antimicrobial agents and chemotherapy

Avec: Fabian Bernhard , Rajesh Odedra , Sylvie Sordello , Rossella Cardin , Samantha Franzoni , Cédric Charrier , Adam Belley , Peter Warn , Matthias Machacek , Philipp Knechtle

Population Pharmacokinetic/Pharmacodynamic Modeling of Glenzocimab (ACT017) a Glycoprotein VI Inhibitor of Collagen-Induced Platelet Aggregation.

Journal of clinical pharmacology

Avec: Lionel Renaud , Kristell Lebozec , Christine Voors-Pette , Peter Dogterom , Philippe Billiald , Martine Jandrot Perrus , Yannick Pletan , Matthias Machacek

Modeling the activation of the alternative complement pathway and its effects on hemolysis in health and disease.

PLoS computational biology

Avec: Antonello Caruso , Jannik Vollmer , Matthias Machacek , Elod Kortvely

Impact of Nutrients on the Hoof Health in Cattle.

Animals : an open access journal from MDPI

Avec: Lucie Langova , Ivana Novotna , Petra Nemcova , Miroslav Machacek , Zdenek Havlicek , Monika Zemanova , Vladimir Chrast

NfL concentration in CSF is a quantitative marker of the rate of neurodegeneration in aging and Huntington's disease: a semi-mechanistic model-based analysis.

Frontiers in neuroscience

Avec: Matthias Machacek , Elena Garcia-Montoya , Peter McColgan , Patricia Sanwald-Ducray , Norman Alan Mazer

A proteolytic method for evaluating O-GlcNAcylation on proteins of similar molecular weight to antibody heavy chain after immunoprecipitation.

Analytical biochemistry

Avec: Miranda Machacek , Patrick E Fields , Chad Slawson

Half-life extension and non-human primate pharmacokinetic safety studies of i-body AD-114 targeting human CXCR4.

mAbs

Avec: Katherine Griffiths , Uli Binder , William McDowell , Rita Tommasi , Mark Frigerio , William G Darby , Chris G Hosking , Lionel Renaud , Matthias Machacek , Peter Lloyd , Arne Skerra , Michael Foley

Regulation and role of endoglin in cholesterol-induced endothelial and vascular dysfunction

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Avec: Matej Vicen , Barbora Vitverova , Radim Havelek , Katerina Blazickova , Miloslav Machacek , Jana Rathouska , Iveta Najmanová , Eva Dolezelova , Alena Prasnicka , Magdalena Sternak , Carmelo Bernabeu , Petr Nachtigal

Dually directional glycosylated phthalocyanines as extracellular red-emitting fluorescent probes.

Dalton transactions (Cambridge, England : 2003)

Avec: Ali Husain , Asaithampi Ganesan , Miloslav Machacek , Lukas Cerveny , Pavel Kubat , Basma Ghazal , Petr Zimcik , Saad Makhseed

Subphthalocyanines as Efficient Photosensitizers with Nanomolar Photodynamic Activity against Cancer Cells.

Journal of medicinal chemistry

Avec: Jiri Demuth , Lucia Gallego , Magdalena Kozlikova , Miloslav Machacek , Radim Kucera , Tomas Torres , M Victoria Martinez-Diaz , Veronika Novakova

Cells

Avec: Ivona Pavkova , Monika Kopeckova , Marek Link , Erik Vlcak , Vlada Filimonenko , Lenka Lecova , Jitka Zakova , Pavlina Laskova , Valeria Sheshko , Miloslav Machacek , Jiri Stulik

Fabrication and characterization of new levan@CBD biocomposite sponges as potential materials in natural, non-toxic wound dressing applications.

International journal of biological macromolecules

Avec: Dorota Chelminiak-Dudkiewicz , Miloslav Machacek , Jolanta Dlugaszewska , Magdalena Wujak , Aleksander Smolarkiewicz-Wyczachowski , Szymon Bocian , Kinga Mylkie , T Goslinski , Michal P Marszall , Marta Ziegler-Borowska

Prediction of Cardiac ATTR Depletion by NI006 (ALXN2220) Using Mechanistic PK/PD Modeling.

Clinical pharmacology and therapeutics

Avec: Aubin Michalon , Lionel Renaud , Matthias Machacek , Cédric Cortijo , Chandrasekhar Udata , Michele F Mercuri , Fabian Buller , Christoph Hock , Roger M Nitsch , Peter C Kahr , Jan Grimm

Cationic Versus Anionic Phthalocyanines for Photodynamic Therapy: What a Difference the Charge Makes.

Journal of medicinal chemistry

Avec: Jan Kollar , Miloslav Machacek , Marie Halaskova , Juraj Lenco , Radim Kucera , Jiri Demuth , Monika Rohlickova , Katerina Hasonova , Miroslav Miletin , Veronika Novakova , Petr Zimcik

Identification of free fatty acid receptor 2 agonists using virtual screening.

Bioorganic & medicinal chemistry letters

Avec: James I Fells , Xi Ai , Adam Weinglass , Wen Feng , Ying Lei , Michael Finley , Hamid R Hoveyda , Graeme L Fraser , Michelle Machacek

How to become a breast cancer specialist in 2018: The point of view of the second cohort of the Certificate of Competence in Breast Cancer (CCB2).

Breast (Edinburgh, Scotland)

Avec: Giacomo Montagna , David Anderson , Justyna Bochenek-Cibor , Ivana Bozovic-Spasojevic , Conceicao Campos , Sandro Cavallero , Ivana Durutovic , Manuel Oscar Gomez Cuadra , Tazia Irfan , Laetita Joly , Loay Kassem , Theresa M Kolben , Martina Machacek , Benazir Mir Khan , Mayur Nagvekar , Benedetta Pellegrino , Katarzyna Pogoda , Gabriela Rodrigues Câmara , Pedro Santos Ferreira , Melsi Seferi , Narmin Talibova , Nathalie Van den Rul , Elen Vettus , Nicola Rocco

Elevated

The Journal of biological chemistry

Avec: Miranda Machacek , Harmony Saunders , Zhen Zhang , Ee Phie Tan , Jibiao Li , Tiangang Li , Maria T Villar , Antonio Artigues , Todd Lydic , Gentry Cork , Chad Slawson , Patrick E Fields

Identification of predictive genetic signatures of Cytarabine responsiveness using a 3D acute myeloid leukaemia model.

Journal of cellular and molecular medicine

Avec: Haiyan Xu , Eric S Muise , Sarah Javaid , Lan Chen , Razvan Cristescu , My Sam Mansueto , Nicole Follmer , Jennifer Cho , Kimberley Kerr , Rachel Altura , Michelle Machacek , Benjamin Nicholson , George Addona , Ilona Kariv , Hongmin Chen

Peripherally Crowded Cationic Phthalocyanines as Efficient Photosensitizers for Photodynamic Therapy.

ACS medicinal chemistry letters

Avec: Marie Halaskova , Asma Rahali , Verónica Almeida-Marrero , Miloslav Machacek , Radim Kucera , Bassem Jamoussi , Tomás Torres , Veronika Novakova , Andrés de la Escosura , Petr Zimcik

Amphiphilic Cationic Phthalocyanines for Photodynamic Therapy of Cancer.

ChemPlusChem

Avec: Marie Halaskova , Filip Kostelansky , Jiri Demuth , Ingrid Hlbocanova , Miroslav Miletin , Petr Zimcik , Miloslav Machacek , Veronika Novakova

Characterization of the Pharmacokinetic and Pharmacodynamic Profile of Apraglutide, a Glucagon-Like Peptide-2 Analog, in Healthy Volunteers.

The Journal of pharmacology and experimental therapeutics

Avec: Federico Bolognani , Annelieke C Kruithof , Pascal Schulthess , Matthias Machacek , Marieke L de Kam , Kirsten R Bergmann , Max van Gent , Matthijs Moerland , Pascal Crenn , Gérard Greig , Pim Gal

Safety and Tolerability, Pharmacokinetics, and Pharmacodynamics of ACT017, an Antiplatelet GPVI (Glycoprotein VI) Fab.

Arteriosclerosis, thrombosis, and vascular biology

Avec: Christine Voors-Pette , Kristell Lebozec , Peter Dogterom , Laurie Jullien , Philippe Billiald , Pauline Ferlan , Lionel Renaud , Olivier Favre-Bulle , Gilles Avenard , Matthias Machacek , Yannick Plétan , Martine Jandrot-Perrus

Red-Emitting Fluorescence Sensors for Metal Cations: The Role of Counteranions and Sensing of SCN

ACS sensors

Avec: Lukas Lochman , Miloslav Machacek , Miroslav Miletin , Štěpánka Uhlířová , Kamil Lang , Kaplan Kirakci , Petr Zimcik , Veronika Novakova

Tuning Photodynamic Properties of BODIPY Dyes, Porphyrins' Little Sisters.

Molecules (Basel, Switzerland)

Avec: Wojciech Krzemien , Monika Rohlickova , Miloslav Machacek , Veronika Novakova , Jaroslaw Piskorz , Petr Zimcik

Impact of a brochure and empathetic physician communication on patients' perception of breast biopsies.

Archives of gynecology and obstetrics

Avec: Martina Machacek , Corinne Urech , Sibil Tschudin , Laura Werlen , Cora-Ann Schoenenberger , Rosanna Zanetti-Dällenbach

Monomerization of Phthalocyanines in Water via Their Supramolecular Interactions with Cucurbiturils.

The Journal of organic chemistry

Avec: Lucia Kociscakova , Carola Rando , Magdalena Kozlikova , Miloslav Machacek , Veronika Novakova , Vladimír Šindelář , Petr Zimcik

Réseau de co-auteurs

Miloslav Machacek 11 collaborations

Matthias Machacek 8 collaborations

Petr Zimcik 7 collaborations

Veronika Novakova 7 collaborations

Lionel Renaud 4 collaborations

Jiri Demuth 3 collaborations

Radim Kucera 3 collaborations

Marie Halaskova 3 collaborations

Miroslav Miletin 3 collaborations

Kristell Lebozec 2 collaborations

Christine Voors-Pette 2 collaborations

Peter Dogterom 2 collaborations

Philippe Billiald 2 collaborations

Miranda Machacek 2 collaborations

Patrick E Fields 2 collaborations

Chad Slawson 2 collaborations

Magdalena Kozlikova 2 collaborations

Monika Rohlickova 2 collaborations

Martina Machacek 2 collaborations

Fabian Bernhard 1 collaboration

Rajesh Odedra 1 collaboration

Sylvie Sordello 1 collaboration

Rossella Cardin 1 collaboration

Samantha Franzoni 1 collaboration

Cédric Charrier 1 collaboration

Adam Belley 1 collaboration

Peter Warn 1 collaboration

Philipp Knechtle 1 collaboration

Martine Jandrot Perrus 1 collaboration

Yannick Pletan 1 collaboration

Antonello Caruso 1 collaboration

Jannik Vollmer 1 collaboration

Elod Kortvely 1 collaboration

Lucie Langova 1 collaboration

Ivana Novotna 1 collaboration

Petra Nemcova 1 collaboration

Miroslav Machacek 1 collaboration

Zdenek Havlicek 1 collaboration

Monika Zemanova 1 collaboration

Vladimir Chrast 1 collaboration

Elena Garcia-Montoya 1 collaboration

Peter McColgan 1 collaboration

Patricia Sanwald-Ducray 1 collaboration

Norman Alan Mazer 1 collaboration

Katherine Griffiths 1 collaboration

Uli Binder 1 collaboration

William McDowell 1 collaboration

Rita Tommasi 1 collaboration

Mark Frigerio 1 collaboration

William G Darby 1 collaboration

Chris G Hosking 1 collaboration

Peter Lloyd 1 collaboration

Arne Skerra 1 collaboration

Michael Foley 1 collaboration

Matej Vicen 1 collaboration

Barbora Vitverova 1 collaboration

Radim Havelek 1 collaboration

Katerina Blazickova 1 collaboration

Jana Rathouska 1 collaboration

Iveta Najmanová 1 collaboration

Eva Dolezelova 1 collaboration

Alena Prasnicka 1 collaboration

Magdalena Sternak 1 collaboration

Carmelo Bernabeu 1 collaboration

Petr Nachtigal 1 collaboration

Ali Husain 1 collaboration

Asaithampi Ganesan 1 collaboration

Lukas Cerveny 1 collaboration

Pavel Kubat 1 collaboration

Basma Ghazal 1 collaboration

Saad Makhseed 1 collaboration

Lucia Gallego 1 collaboration

Tomas Torres 1 collaboration

M Victoria Martinez-Diaz 1 collaboration

Ivona Pavkova 1 collaboration

Monika Kopeckova 1 collaboration

Marek Link 1 collaboration

Erik Vlcak 1 collaboration

Vlada Filimonenko 1 collaboration

Lenka Lecova 1 collaboration

Jitka Zakova 1 collaboration

Pavlina Laskova 1 collaboration

Valeria Sheshko 1 collaboration

Jiri Stulik 1 collaboration

Dorota Chelminiak-Dudkiewicz 1 collaboration

Jolanta Dlugaszewska 1 collaboration

Magdalena Wujak 1 collaboration

Aleksander Smolarkiewicz-Wyczachowski 1 collaboration

Szymon Bocian 1 collaboration

Kinga Mylkie 1 collaboration

T Goslinski 1 collaboration

Michal P Marszall 1 collaboration

Marta Ziegler-Borowska 1 collaboration

Aubin Michalon 1 collaboration

Cédric Cortijo 1 collaboration

Chandrasekhar Udata 1 collaboration

Michele F Mercuri 1 collaboration

Fabian Buller 1 collaboration

Christoph Hock 1 collaboration

Roger M Nitsch 1 collaboration

Peter C Kahr 1 collaboration

Jan Grimm 1 collaboration

Jan Kollar 1 collaboration

Juraj Lenco 1 collaboration

Katerina Hasonova 1 collaboration

James I Fells 1 collaboration

Xi Ai 1 collaboration

Adam Weinglass 1 collaboration

Wen Feng 1 collaboration

Ying Lei 1 collaboration

Michael Finley 1 collaboration

Hamid R Hoveyda 1 collaboration

Graeme L Fraser 1 collaboration

Giacomo Montagna 1 collaboration

David Anderson 1 collaboration

Justyna Bochenek-Cibor 1 collaboration

Ivana Bozovic-Spasojevic 1 collaboration

Conceicao Campos 1 collaboration

Sandro Cavallero 1 collaboration

Ivana Durutovic 1 collaboration

Manuel Oscar Gomez Cuadra 1 collaboration

Tazia Irfan 1 collaboration

Laetita Joly 1 collaboration

Loay Kassem 1 collaboration

Theresa M Kolben 1 collaboration

Benazir Mir Khan 1 collaboration

Mayur Nagvekar 1 collaboration

Benedetta Pellegrino 1 collaboration

Katarzyna Pogoda 1 collaboration

Gabriela Rodrigues Câmara 1 collaboration

Pedro Santos Ferreira 1 collaboration

Melsi Seferi 1 collaboration

Narmin Talibova 1 collaboration

Nathalie Van den Rul 1 collaboration

Elen Vettus 1 collaboration

Nicola Rocco 1 collaboration

Harmony Saunders 1 collaboration

Zhen Zhang 1 collaboration

Ee Phie Tan 1 collaboration

Jibiao Li 1 collaboration

Tiangang Li 1 collaboration

Maria T Villar 1 collaboration

Antonio Artigues 1 collaboration

Todd Lydic 1 collaboration

Gentry Cork 1 collaboration

Haiyan Xu 1 collaboration

Eric S Muise 1 collaboration

Sarah Javaid 1 collaboration

Lan Chen 1 collaboration

Razvan Cristescu 1 collaboration

My Sam Mansueto 1 collaboration

Nicole Follmer 1 collaboration

Jennifer Cho 1 collaboration

Kimberley Kerr 1 collaboration

Rachel Altura 1 collaboration

Benjamin Nicholson 1 collaboration

George Addona 1 collaboration

Ilona Kariv 1 collaboration

Hongmin Chen 1 collaboration

Asma Rahali 1 collaboration

Verónica Almeida-Marrero 1 collaboration

Bassem Jamoussi 1 collaboration

Tomás Torres 1 collaboration

Andrés de la Escosura 1 collaboration

Filip Kostelansky 1 collaboration

Ingrid Hlbocanova 1 collaboration

Federico Bolognani 1 collaboration

Annelieke C Kruithof 1 collaboration

Pascal Schulthess 1 collaboration

Marieke L de Kam 1 collaboration

Kirsten R Bergmann 1 collaboration

Max van Gent 1 collaboration

Matthijs Moerland 1 collaboration

Pascal Crenn 1 collaboration

Gérard Greig 1 collaboration

Pim Gal 1 collaboration

Laurie Jullien 1 collaboration

Pauline Ferlan 1 collaboration

Olivier Favre-Bulle 1 collaboration

Gilles Avenard 1 collaboration

Yannick Plétan 1 collaboration

Martine Jandrot-Perrus 1 collaboration

Lukas Lochman 1 collaboration

Štěpánka Uhlířová 1 collaboration

Kamil Lang 1 collaboration

Kaplan Kirakci 1 collaboration

Wojciech Krzemien 1 collaboration

Jaroslaw Piskorz 1 collaboration

Corinne Urech 1 collaboration

Sibil Tschudin 1 collaboration

Laura Werlen 1 collaboration

Cora-Ann Schoenenberger 1 collaboration

Rosanna Zanetti-Dällenbach 1 collaboration

Lucia Kociscakova 1 collaboration

Carola Rando 1 collaboration

Vladimír Šindelář 1 collaboration