Nevin Witman

Affiliations

Department of Cell and Molecular Biology, Karolinska Institutet, Stockholm 171 77, Sweden; Department of Medicine-Cardiology, Karolinska Institutet, Stockholm 141 86, Sweden.

Publications (19)

Population and Single-Cell Analysis of Human Cardiogenesis Reveals Unique LGR5 Ventricular Progenitors in Embryonic Outflow Tract.

Developmental cell

Avec: Makoto Sahara , Federica Santoro , Jesper Sohlmér , Chikai Zhou , Nevin Witman , Chuen Yan Leung , Mimmi Mononen , Kristine Bylund , Peter Gruber , Kenneth R Chien

BMP-2 and VEGF-A modRNAs in collagen scaffold synergistically drive bone repair through osteogenic and angiogenic pathways.

Communications biology

Avec: Yingnan Geng , Huichuan Duan , Liang Xu , Nevin Witman , Bingqian Yan , Zheyuan Yu , Huijing Wang , Yao Tan , Liqin Lin , Dong Li , Shanshan Bai , Regina Fritsche-Danielson , Jie Yuan , Kenneth Chien , Min Wei , Wei Fu

An mRNA assay system demonstrates proteasomal-specific degradation contributes to cardiomyopathic phospholamban null mutation.

Molecular medicine (Cambridge, Mass.)

Avec: Eduarde Rohner , Nevin Witman , Jesper Sohlmer , Erwin De Genst , William E Louch , Makoto Sahara , Kenneth R Chien

Enhanced adipose-derived stem cells with IGF-1-modified mRNA promote wound healing following corneal injury.

Molecular therapy : the journal of the American Society of Gene Therapy

Avec: Fei Yu , Danni Gong , Dan Yan , Huijing Wang , Nevin Witman , Yang Lu , Wei Fu , Yao Fu

Yohimbine Directly Induces Cardiotoxicity on Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes.

Cardiovascular toxicology

Avec: Yiqi Gong , Li Yang , Jun Tang , Jijian Zheng , Nevin Witman , Philipp Jakob , Yao Tan , Minglu Liu , Ying Chen , Huijing Wang , Wei Fu , Wei Wang

Engineering a conduction-consistent cardiac patch with graphene oxide modified butterfly wings and human pluripotent stem cell-derived cardiomyocytes.

Bioengineering & translational medicine

Avec: Yao Tan , Tingting Lu , Ying Chen , Nevin Witman , Bingqian Yan , Li Yang , Minglu Liu , Yiqi Gong , Xuefeng Ai , Runjiao Luo , Huijing Wang , Wei Wang , Wei Fu

Endovascular transplantation of mRNA-enhanced mesenchymal stromal cells results in superior therapeutic protein expression in swine heart.

Molecular therapy. Methods & clinical development

Avec: Jonathan Al-Saadi , Mathias Waldén , Mikael Sandell , Jesper Sohlmér , Rikard Grankvist , Ida Friberger , Agneta Andersson , Mattias Carlsten , Kenneth Chien , Johan Lundberg , Nevin Witman , Staffan Holmin

Cardiac progenitors and paracrine mediators in cardiogenesis and heart regeneration.

Seminars in cell & developmental biology

Avec: Nevin Witman , Chikai Zhou , Niels Grote Beverborg , Makoto Sahara , Kenneth R Chien

Human adipose-derived stem cells enriched with VEGF-modified mRNA promote angiogenesis and long-term graft survival in a fat graft transplantation model.

Stem cell research & therapy

Avec: Fei Yu , Nevin Witman , Dan Yan , Siyi Zhang , Meng Zhou , Yan Yan , Qinke Yao , Feixue Ding , Bingqian Yan , Huijing Wang , Wei Fu , Yang Lu , Yao Fu

Epicardium-derived cells organize through tight junctions to replenish cardiac muscle in salamanders.

Nature cell biology

Avec: Elif Eroglu , Christopher Y T Yen , Yat-Long Tsoi , Nevin Witman , Ahmed Elewa , Alberto Joven Araus , Heng Wang , Tamara Szattler , Chimezie H Umeano , Jesper Sohlmér , Alexander Goedel , András Simon , Kenneth R Chien

Engineering a conduction-consistent cardiac patch with rGO/PLCL electrospun nanofibrous membranes and human iPSC-derived cardiomyocytes.

Frontiers in bioengineering and biotechnology

Avec: Yao Tan , Ying Chen , Tingting Lu , Nevin Witman , Bingqian Yan , Yiqi Gong , Xuefeng Ai , Li Yang , Minglu Liu , Runjiao Luo , Huijing Wang , Stefano Ministrini , Wei Dong , Wei Wang , Wei Fu

Placental growth factor exerts a dual function for cardiomyogenesis and vasculogenesis during heart development.

Nature communications

Avec: Nevin Witman , Chikai Zhou , Timm Häneke , Yao Xiao , Xiaoting Huang , Eduarde Rohner , Jesper Sohlmér , Niels Grote Beverborg , Kenneth R Chien , Makoto Sahara

Cell-mediated delivery of VEGF modified mRNA enhances blood vessel regeneration and ameliorates murine critical limb ischemia.

Journal of controlled release : official journal of the Controlled Release Society

Avec: Ziyou Yu , Nevin Witman , Wenbo Wang , Dong Li , Bingqian Yan , Mingwu Deng , Xiangsheng Wang , Huijing Wang , Guangdong Zhou , Wei Liu , Makoto Sahara , Yilin Cao , Regina Fritsche-Danielson , Wenjie Zhang , Wei Fu , Kenneth R Chien

Tissue-engineered trachea from a 3D-printed scaffold enhances whole-segment tracheal repair in a goat model.

Journal of tissue engineering and regenerative medicine

Avec: Dekai Xia , Dawei Jin , Qian Wang , Manchen Gao , Jialing Zhang , Hengyi Zhang , Jie Bai , Bei Feng , Maolin Chen , Yanhui Huang , Yumin Zhong , Nevin Witman , Wei Wang , Zhiwei Xu , Haibo Zhang , Meng Yin , Wei Fu

Intrinsic Color Sensing System Allows for Real-Time Observable Functional Changes on Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes.

ACS nano

Avec: Yiqi Gong , Zhuoyue Chen , Li Yang , Xuefeng Ai , Bingqian Yan , Huijing Wang , Liya Qiu , Yao Tan , Nevin Witman , Wei Wang , Yuanjin Zhao , Wei Fu

Dexmedetomidine exhibits antiarrhythmic effects on human-induced pluripotent stem cell-derived cardiomyocytes through a Na/Ca channel-mediated mechanism.

Annals of translational medicine

Avec: Li Yang , Yiqi Gong , Yao Tan , Lei Wu , Nevin Witman , Jijian Zheng , Jun Zhang , Wei Fu , Wei Wang

Amnion signals are essential for mesoderm formation in primates.

Nature communications

Avec: Ran Yang , Alexander Goedel , Yu Kang , Chenyang Si , Chu Chu , Yi Zheng , Zhenzhen Chen , Peter J Gruber , Yao Xiao , Chikai Zhou , Nevin Witman , Elif Eroglu , Chuen-Yan Leung , Yongchang Chen , Jianping Fu , Weizhi Ji , Fredrik Lanner , Yuyu Niu , Kenneth R Chien

Blocking phospholamban with VHH intrabodies enhances contractility and relaxation in heart failure.

Nature communications

Avec: Erwin De Genst , Kylie S Foo , Yao Xiao , Eduarde Rohner , Emma de Vries , Jesper Sohlmér , Nevin Witman , Alejandro Hidalgo , Terje R S Kolstad , William E Louch , Susanne Pehrsson , Andrew Park , Yasuhiro Ikeda , Xidan Li , Lorenz M Mayr , Kate Wickson , Karin Jennbacken , Kenny Hansson , Regina Fritsche-Danielson , James Hunt , Kenneth R Chien

Transient secretion of VEGF protein from transplanted hiPSC-CMs enhances engraftment and improves rat heart function post MI.

Molecular therapy : the journal of the American Society of Gene Therapy

Avec: Xuefeng Ai , Bingqian Yan , Nevin Witman , Yiqi Gong , Li Yang , Yao Tan , Ying Chen , Minglu Liu , Tingting Lu , Runjiao Luo , Huijing Wang , Kenneth R Chien , Wei Wang , Wei Fu

Réseau de co-auteurs

Wei Fu 11 collaborations

Kenneth R Chien 9 collaborations

Huijing Wang 9 collaborations

Bingqian Yan 7 collaborations

Yao Tan 7 collaborations

Wei Wang 7 collaborations

Yiqi Gong 6 collaborations

Li Yang 6 collaborations

Makoto Sahara 5 collaborations

Jesper Sohlmér 5 collaborations

Chikai Zhou 4 collaborations

Minglu Liu 4 collaborations

Ying Chen 4 collaborations

Xuefeng Ai 4 collaborations

Regina Fritsche-Danielson 3 collaborations

Eduarde Rohner 3 collaborations

Tingting Lu 3 collaborations

Runjiao Luo 3 collaborations

Yao Xiao 3 collaborations

Dong Li 2 collaborations

Kenneth Chien 2 collaborations

Erwin De Genst 2 collaborations

William E Louch 2 collaborations

Fei Yu 2 collaborations

Dan Yan 2 collaborations

Yang Lu 2 collaborations

Yao Fu 2 collaborations

Jijian Zheng 2 collaborations

Niels Grote Beverborg 2 collaborations

Elif Eroglu 2 collaborations

Alexander Goedel 2 collaborations

Federica Santoro 1 collaboration

Chuen Yan Leung 1 collaboration

Mimmi Mononen 1 collaboration

Kristine Bylund 1 collaboration

Peter Gruber 1 collaboration

Yingnan Geng 1 collaboration

Huichuan Duan 1 collaboration

Liang Xu 1 collaboration

Zheyuan Yu 1 collaboration

Liqin Lin 1 collaboration

Shanshan Bai 1 collaboration

Jie Yuan 1 collaboration

Min Wei 1 collaboration

Jesper Sohlmer 1 collaboration

Danni Gong 1 collaboration

Jun Tang 1 collaboration

Philipp Jakob 1 collaboration

Jonathan Al-Saadi 1 collaboration

Mathias Waldén 1 collaboration

Mikael Sandell 1 collaboration

Rikard Grankvist 1 collaboration

Ida Friberger 1 collaboration

Agneta Andersson 1 collaboration

Mattias Carlsten 1 collaboration

Johan Lundberg 1 collaboration

Staffan Holmin 1 collaboration

Siyi Zhang 1 collaboration

Meng Zhou 1 collaboration

Yan Yan 1 collaboration

Qinke Yao 1 collaboration

Feixue Ding 1 collaboration

Christopher Y T Yen 1 collaboration

Yat-Long Tsoi 1 collaboration

Ahmed Elewa 1 collaboration

Alberto Joven Araus 1 collaboration

Heng Wang 1 collaboration

Tamara Szattler 1 collaboration

Chimezie H Umeano 1 collaboration

András Simon 1 collaboration

Stefano Ministrini 1 collaboration

Wei Dong 1 collaboration

Timm Häneke 1 collaboration

Xiaoting Huang 1 collaboration

Ziyou Yu 1 collaboration

Wenbo Wang 1 collaboration

Mingwu Deng 1 collaboration

Xiangsheng Wang 1 collaboration

Guangdong Zhou 1 collaboration

Wei Liu 1 collaboration

Yilin Cao 1 collaboration

Wenjie Zhang 1 collaboration

Dekai Xia 1 collaboration

Dawei Jin 1 collaboration

Qian Wang 1 collaboration

Manchen Gao 1 collaboration

Jialing Zhang 1 collaboration

Hengyi Zhang 1 collaboration

Jie Bai 1 collaboration

Bei Feng 1 collaboration

Maolin Chen 1 collaboration

Yanhui Huang 1 collaboration

Yumin Zhong 1 collaboration

Zhiwei Xu 1 collaboration

Haibo Zhang 1 collaboration

Meng Yin 1 collaboration

Zhuoyue Chen 1 collaboration

Liya Qiu 1 collaboration

Yuanjin Zhao 1 collaboration

Lei Wu 1 collaboration

Jun Zhang 1 collaboration

Ran Yang 1 collaboration

Yu Kang 1 collaboration

Chenyang Si 1 collaboration

Chu Chu 1 collaboration

Yi Zheng 1 collaboration

Zhenzhen Chen 1 collaboration

Peter J Gruber 1 collaboration

Chuen-Yan Leung 1 collaboration

Yongchang Chen 1 collaboration

Jianping Fu 1 collaboration

Weizhi Ji 1 collaboration

Fredrik Lanner 1 collaboration

Yuyu Niu 1 collaboration

Kylie S Foo 1 collaboration

Emma de Vries 1 collaboration

Alejandro Hidalgo 1 collaboration

Terje R S Kolstad 1 collaboration

Susanne Pehrsson 1 collaboration

Andrew Park 1 collaboration

Yasuhiro Ikeda 1 collaboration

Xidan Li 1 collaboration

Lorenz M Mayr 1 collaboration

Kate Wickson 1 collaboration

Karin Jennbacken 1 collaboration

Kenny Hansson 1 collaboration

James Hunt 1 collaboration