Nicholas Isambert

Affiliations
  • Centre Georges Francois Leclerc, 21000 Dijon, France.

Publications (55)

A phase II of gemcitabine combined with pazopanib followed by pazopanib maintenance, as second-line treatment in patients with advanced leiomyosarcomas: A unicancer French Sarcoma Group study (LMS03 study).

European journal of cancer (Oxford, England : 1990)
Avec: P Pautier , N Penel , I Ray-Coquard , A Italiano , E Bompas , C Delcambre , J-O Bay , F Bertucci , J Delaye , C Chevreau , D Cupissol , L Bozec , J-C Eymard , E Saada , N Isambert , C Guillemet , M Rios , S Piperno-Neumann , G Chenuc , F Duffaud

TAKTIC: A prospective, multicentre, uncontrolled, phase IB/II study of LY2780301, a p70S6K/AKT inhibitor, in combination with weekly paclitaxel in HER2-negative advanced breast cancer patients.

European journal of cancer (Oxford, England : 1990)
Avec: Cecile Vicier , Patrick Sfumato , Nicolas Isambert , Florence Dalenc , Marie Robert , Christelle Levy , Keyvan Rezai , Magali Provansal , José Adélaïde , Séverine Garnier , Arnaud Guille , Nadine Carbuccia , Cornel Popovici , Emmanuelle Charafe-Jauffret , Max Chaffanet , Daniel Birnbaum , Jihane Pakradouni , François Bertucci , Jean M Boher , Renaud Sabatier , Anthony Gonçalves

Two phase I studies of BI 836880, a vascular endothelial growth factor/angiopoietin-2 inhibitor, administered once every 3 weeks or once weekly in patients with advanced solid tumors.

ESMO open
Avec: C Le Tourneau , H Becker , R Claus , E Elez , F Ricci , R Fritsch , Y Silber , A Hennequin , J Tabernero , G Jayadeva , D Luedtke , M He , N Isambert

Effect of capmatinib on the pharmacokinetics of substrates of CYP3A (midazolam) and CYP1A2 (caffeine) in patients with MET-dysregulated solid tumours.

British journal of clinical pharmacology
Avec: Xinhui Chen , Nicolas Isambert , Rafael López-López , Monica Giovannini , Nathalie Pognan , Shruti Kapoor , Michelle Quinlan , Benoit You , Xiaoming Cui , Gholamreza Rahmanzadeh , Morten Mau-Sorensen

ONCOS-102 plus pemetrexed and platinum chemotherapy in malignant pleural mesothelioma: a randomized phase 2 study investigating clinical outcomes and the tumor microenvironment.

Journal for immunotherapy of cancer
Avec: Santiago Ponce , Susana Cedrés , Charles Ricordel , Nicolas Isambert , Santiago Viteri , Mercedes Herrera-Juarez , Alex Martinez-Marti , Alejandro Navarro , Mathieu Lederlin , Xavier Serres , Jon Zugazagoitia , Sylvia Vetrhus , Magnus Jaderberg , Thomas Birkballe Hansen , Victor Levitsky , Luis Paz-Ares

Doxorubicin-Trabectedin with Trabectedin Maintenance in Leiomyosarcoma.

The New England journal of medicine
Avec: Patricia Pautier , Antoine Italiano , Sophie Piperno-Neumann , Christine Chevreau , Nicolas Penel , Nelly Firmin , Pascaline Boudou-Rouquette , François Bertucci , Valérie Lebrun-Ly , Isabelle Ray-Coquard , Elsa Kalbacher , Emmanuelle Bompas , Olivier Collard , Nicolas Isambert , Cécile Guillemet , Maria Rios , Axel Le Cesne , Corinne Balleyguier , Baptiste Archambaud , Florence Duffaud , Auteur inconnu

A randomized double-blind phase II study evaluating the role of maintenance therapy with cabozantinib in high-grade uterine sarcoma after stabilization or response to doxorubicin ± ifosfamide following surgery or in metastatic first line treatment (EORTC62113).

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society
Avec: Isabelle Ray-Coquard , Helen Hatcher , Emmanuelle Bompas , Antonio Casado , Annekke Westermann , Nicolas Isambert , Paolo Giovanni Casali , Sarah Pratap , Daniel Stark , Claudia Valverde , Anjana Anand , Manon Huizing , Anne Floquet , Lars Lindner , Barbara Hermes , Beatrice Seddon , Corneel Coens , Robin Jones , Nick Reed

Pazopanib or methotrexate-vinblastine combination chemotherapy in adult patients with progressive desmoid tumours (DESMOPAZ): a non-comparative, randomised, open-label, multicentre, phase 2 study.

The Lancet. Oncology
Avec: Maud Toulmonde , Marina Pulido , Isabelle Ray-Coquard , Thierry Andre , Nicolas Isambert , Christine Chevreau , Nicolas Penel , Emmanuelle Bompas , Esma Saada , François Bertucci , Celeste Lebbe , Axel Le Cesne , Patrick Soulie , Sophie Piperno-Neumann , Stephen Sweet , Fabiola Cecchi , Todd Hembrough , Carine Bellera , Michèle Kind , Amandine Crombe , Carlo Lucchesi , François Le Loarer , Jean-Yves Blay , Antoine Italiano

Activity and Safety of Palbociclib in Patients with Advanced Gastrointestinal Stromal Tumors Refractory to Imatinib and Sunitinib: A Biomarker-driven Phase II Study.

Clinical cancer research : an official journal of the American Association for Cancer Research
Avec: Maud Toulmonde , Jean-Yves Blay , Olivier Bouche , Olivier Mir , Nicolas Penel , Nicolas Isambert , Florence Duffaud , Emmanuelle Bompas , Thomas Esnaud , Romain Boidot , Damien Geneste , François Ghiringhelli , Carlo Lucchesi , Carine A Bellera , François Le Loarer , Antoine Italiano

Efficacy and safety of regorafenib in adult patients with metastatic osteosarcoma: a non-comparative, randomised, double-blind, placebo-controlled, phase 2 study.

The Lancet. Oncology
Avec: Florence Duffaud , Olivier Mir , Pascaline Boudou-Rouquette , Sophie Piperno-Neumann , Nicolas Penel , Emanuelle Bompas , Corinne Delcambre , Elsa Kalbacher , Antoine Italiano , Olivier Collard , Christine Chevreau , Esma Saada , Nicolas Isambert , Jessy Delaye , Camille Schiffler , Corinne Bouvier , Vincent Vidal , Sylvie Chabaud , Jean-Yves Blay , Auteur inconnu

Therapeutic Challenges in Patients with Gynecologic Carcinosarcomas: Analysis of a Multicenter National Cohort Study from the French Prospective TMRG Network.

Cancers
Avec: Clémence Romeo , Olivia Le Saux , Margaux Jacobs , Florence Joly , Gwenael Ferron , Laure Favier , Jean-David Fumet , Nicolas Isambert , Pierre-Emmanuel Colombo , Renaud Sabatier , Ludovic Bastide , Amandine Charreton , Mojgan Devouassoux-Shisheboran , Witold Gertych , Coraline Dubot , Diana Bello Roufai , Guillaume Bataillon , Dominique Berton , Elsa Kalbacher , Patricia Pautier , Christophe Pomel , Caroline Cornou , Isabelle Treilleux , Audrey Lardy-Cleaud , Isabelle Ray-Coquard

Phase I trial of copanlisib, a selective PI3K inhibitor, in combination with cetuximab in patients with recurrent and/or metastatic head and neck squamous cell carcinoma.

Investigational new drugs
Avec: Grégoire Marret , Nicolas Isambert , Keyvan Rezai , Jocelyn Gal , Esma Saada-Bouzid , Frédéric Rolland , Maggy Chausson , Edith Borcoman , Marie Alt , Jerzy Klijanienko , Damien Vansteene , Joël Guigay , Maud Kamal , Ivan Bièche , Christophe Le Tourneau , Auteur inconnu

Circulating tumor DNA predicts efficacy of a dual AKT/p70S6K inhibitor (LY2780301) plus paclitaxel in metastatic breast cancer: plasma analysis of the TAKTIC phase IB/II study.

Molecular oncology
Avec: Renaud Sabatier , Cécile Vicier , Séverine Garnier , Arnaud Guille , Nadine Carbuccia , Nicolas Isambert , Florence Dalenc , Marie Robert , Christelle Levy , Jihane Pakradouni , José Adelaïde , Max Chaffanet , Patrick Sfumato , Emilie Mamessier , François Bertucci , Anthony Goncalves

Socio-demographic inequalities in stage at diagnosis of lung cancer: A French population-based study.

Cancer epidemiology
Avec: Alexandre Quillet , Nolwenn Le Stang , Nicolas Meriau , Nicolas Isambert , Gautier Defossez

Prognostic factors and outcomes of adult spermatic cord sarcoma. A study from the French Sarcoma Group.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
Avec: Gilles Achard , Céline Charon-Barra , Sebastien Carrere , Sylvie Bonvalot , Pierre Meeus , Magali Fau , Charles Honoré , Jean-Baptiste Delhorme , Dimitri Tzanis , François Le Loarer , Marie Karanian-Philippe , Carine Ngo , Sophie Le Guellec , Aurélie Bertaut , Sylvain Causeret , Nicolas Isambert

A randomized phase III trial comparing trabectedin to best supportive care in patients with pre-treated soft tissue sarcoma: T-SAR, a French Sarcoma Group trial.

Annals of oncology : official journal of the European Society for Medical Oncology
Avec: A Le Cesne , J-Y Blay , D Cupissol , A Italiano , C Delcambre , N Penel , N Isambert , C Chevreau , E Bompas , F Bertucci , L Chaigneau , S Piperno-Neumann , S Salas , M Rios , C Guillemet , J-O Bay , I Ray-Coquard , L Haddag , J Bonastre , R Kapso , A Fraslin , N Bouvet , O Mir , S Foulon

Limbs and trunk soft tissue sarcoma systematic local and remote monitoring by MRI and thoraco-abdomino-pelvic scanner: A single-centre retrospective study.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
Avec: Floriane De Angelis , France Guy , Aurélie Bertaut , Nathalie Méjean , Olivier Varbedian , Alice Hervieu , Gilles Truc , David Thibouw , Céline Charon Barra , Jean Fraisse , Pierre Burnier , Nicolas Isambert , Sylvain Causeret

Pharmacokinetics and Safety of Olaparib in Patients with Advanced Solid Tumours and Renal Impairment.

Clinical pharmacokinetics
Avec: Christian Rolfo , Judith de Vos-Geelen , Nicolas Isambert , L Rhoda Molife , Jan H M Schellens , Jacques De Grève , Luc Dirix , Peter Grundtvig-Sørensen , Guy Jerusalem , Karin Leunen , Morten Mau-Sørensen , Ruth Plummer , Maria Learoyd , Wendy Bannister , Anitra Fielding , Alain Ravaud

Pharmacokinetics and safety of olaparib in patients with advanced solid tumours and mild or moderate hepatic impairment.

British journal of clinical pharmacology
Avec: Christian Rolfo , Nicolas Isambert , Antoine Italiano , L Rhoda Molife , Jan H M Schellens , Jean-Yves Blay , Thomas Decaens , Rebecca Kristeleit , Olivier Rosmorduc , Regina Demlova , Myung-Ah Lee , Alain Ravaud , Katerina Kopeckova , Maria Learoyd , Wendy Bannister , Gershon Locker , Judith de Vos-Geelen

Development of a disease-specific graded prognostic assessment index for the management of sarcoma patients with brain metastases (Sarcoma-GPA).

BMC cancer
Avec: Anna Patrikidou , Loic Chaigneau , Nicolas Isambert , Kyriaki Kitikidou , Ryan Shanley , Isabelle Ray-Coquard , Thibaud Valentin , Bettina Malivoir , Maryline Laigre , Jacques-Olivier Bay , Laurence Moureau-Zabotto , Emmanuelle Bompas , Sophie Piperno-Neumann , Nicolas Penel , Thierry Alcindor , Cécile Guillemet , Florence Duffaud , Anne Hügli , Cécile Le Pechoux , Frédéric Dhermain , Jean-Yves Blay , Paul W Sperduto , Axel Le Cesne

Starting Imatinib at 400 mg Daily in Patients with Gastrointestinal Stromal Tumors Harboring KIT Exon 9 Mutations: A Retrospective, Multicenter Study.

Targeted oncology
Avec: Almudena Callejo , Sara Faouzi , Olivier Bouché , François Bertucci , Thomas Chevalier , Nicolas Isambert , Florence Duffaud , Olivier Collard , Nicolas Penel , Philippe Terrier , Olivier Mir , Jean Yves Blay , Axel Le Cesne

Rare bone sarcomas: A retrospective analysis of 145 adult patients from the French Sarcoma Group.

International journal of cancer
Avec: Pascaline Boudou-Rouquette , Elodie Martin , Emmanuelle Kempf , Nicolas Penel , Maud Toulmonde , Emmanuelle Bompas , Florence Duffaud , Nelly Firmin , François Bertucci , Jean-Emmanuel Kurtz , Loïc Chaigneau , Nicolas Isambert , Esma Saada-Bouzid , Pascale Dubray-Longeras , Frédérique Larousserie , Philippe Anract , Christine Chevreau , Jean-Yves Blay , Sophie Piperno-Neumann , Auteur inconnu

Genomics to select treatment for patients with metastatic breast cancer.

Nature
Avec: Fabrice Andre , Thomas Filleron , Maud Kamal , Fernanda Mosele , Monica Arnedos , Florence Dalenc , Marie-Paule Sablin , Mario Campone , Hervé Bonnefoi , Claudia Lefeuvre-Plesse , William Jacot , Florence Coussy , Jean-Marc Ferrero , George Emile , Marie-Ange Mouret-Reynier , Jean-Christophe Thery , Nicolas Isambert , Alice Mege , Philippe Barthelemy , Benoit You , Nawale Hajjaji , Ludovic Lacroix , Etienne Rouleau , Alicia Tran-Dien , Sandrine Boyault , Valery Attignon , Pierre Gestraud , Nicolas Servant , Christophe Le Tourneau , Linda Larbi Cherif , Isabelle Soubeyran , Filippo Montemurro , Alain Morel , Amelie Lusque , Marta Jimenez , Alexandra Jacquet , Anthony Gonçalves , Thomas Bachelot , Ivan Bieche

MOVIE: a phase I, open-label, multicenter study to evaluate the safety and tolerability of metronomic vinorelbine combined with durvalumab plus tremelimumab in patients with advanced solid tumors.

ESMO open
Avec: C Vicier , N Isambert , C Cropet , M Hamimed , L Osanno , F Legrand , T de La Motte Rouge , J Ciccolini , A Gonçalves

Bintrafusp Alfa, a Bifunctional Fusion Protein Targeting TGF-β and PD-L1, in Patients With Non-Small Cell Lung Cancer Resistant or Refractory to Immune Checkpoint Inhibitors.

The oncologist
Avec: Fabrice Barlesi , Nicolas Isambert , Enriqueta Felip , Byoung Chul Cho , Dae Ho Lee , Julio Peguero , Guy Jerusalem , Nicolas Penel , Esma Saada-Bouzid , Pilar Garrido , Christoph Helwig , George Locke , Laureen S Ojalvo , James L Gulley

Inequality factors in access to early-phase clinical trials in oncology in France: results of the EGALICAN-2 study.

ESMO open
Avec: E Charton , C Baldini , Y Fayet , E Schultz , L Auroy , E Vallier , A Italiano , M Robert , E Coquan , N Isambert , P Moreau , C Touzeau , C Le Tourneau , Z Ghrieb , J-J Kiladjian , J-P Delord , C Gomez Roca , N Vey , F Barlesi , T Lesimple , N Penel , J-C Soria , C Massard , S Besle

Monitoring HSP70 exosomes in cancer patients' follow up: a clinical prospective pilot study.

Journal of extracellular vesicles
Avec: Gaëtan Chanteloup , Marine Cordonnier , Nicolas Isambert , Aurélie Bertaut , Alice Hervieu , Audrey Hennequin , Maxime Luu , Sylvie Zanetta , Bruno Coudert , Leila Bengrine , Isabelle Desmoulins , Laure Favier , Aurélie Lagrange , Pierre-Benoit Pages , Ivan Gutierrez , Jeanine Lherminier , Laure Avoscan , Clémentine Jankowski , Cédric Rébé , Angélique Chevriaux , Marie-Martine Padeano , Charles Coutant , Sylvain Ladoire , Sylvain Causeret , Laurent Arnould , Céline Charon-Barra , Vanessa Cottet , Julie Blanc , Christine Binquet , Marc Bardou , Carmen Garrido , Jessica Gobbo

Bintrafusp alfa, a bifunctional fusion protein targeting TGF-β and PD-L1, in advanced squamous cell carcinoma of the head and neck: results from a phase I cohort.

Journal for immunotherapy of cancer
Avec: Byoung Chul Cho , Amaury Daste , Alain Ravaud , Sébastien Salas , Nicolas Isambert , Edward McClay , Ahmad Awada , Christian Borel , Laureen S Ojalvo , Christoph Helwig , P Alexander Rolfe , James L Gulley , Nicolas Penel

Ramucirumab plus pembrolizumab in patients with previously treated advanced non-small-cell lung cancer, gastro-oesophageal cancer, or urothelial carcinomas (JVDF): a multicohort, non-randomised, open-label, phase 1a/b trial.

The Lancet. Oncology
Avec: Roy S Herbst , Hendrik-Tobias Arkenau , Rafael Santana-Davila , Emiliano Calvo , Luis Paz-Ares , Philippe A Cassier , Johanna Bendell , Nicolas Penel , Matthew G Krebs , Juan Martin-Liberal , Nicolas Isambert , Andres Soriano , Martin Wermke , Jennifer Cultrera , Ling Gao , Ryan C Widau , Gu Mi , Jin Jin , David Ferry , Charles S Fuchs , Daniel P Petrylak , Ian Chau

Low Cross-Reactivity Between Cisplatin and Other Platinum Salts.

The journal of allergy and clinical immunology. In practice
Avec: Justine Pasteur , Laure Favier , Corinne Pernot , Mathieu Guerriaud , Charlotte Bernigaud , Côme Lepage , Jean-Louis Jouve , Nicolas Isambert , Evelyne Collet

Glyceryl trinitrate‑induced cytotoxicity of docetaxel‑resistant prostatic cancer cells is associated with differential regulation of clusterin.

International journal of oncology
Avec: Sarra Bouaouiche , Lea Magadoux , Lucile Dondaine , Sylvie Reveneau , Nicolas Isambert , Ali Bettaieb , Jean-François Jeannin , Veronique Laurens , Stephanie Plenchette

Serum soluble CD26/DPP4 titer variation is a potential prognostic biomarker in cancer therapy with a humanized anti-CD26 antibody.

Biomarker research
Avec: Yutaro Kaneko , Ryo Hatano , Naoto Hirota , Nicolas Isambert , Véronique Trillet-Lenoir , Benoit You , Jérôme Alexandre , Gérard Zalcman , Fanny Valleix , Thomas Podoll , Yoshimi Umezawa , Seiichi Takao , Satoshi Iwata , Osamu Hosono , Tetsuo Taguchi , Taketo Yamada , Nam H Dang , Kei Ohnuma , Eric Angevin , Chikao Morimoto

Pharmacogenetic Study of Trabectedin-Induced Severe Hepatotoxicity in Patients with Advanced Soft Tissue Sarcoma.

Cancers
Avec: Maud Maillard , Christine Chevreau , Félicien Le Louedec , Manon Cassou , Caroline Delmas , Laure Gourdain , Jean-Yves Blay , Didier Cupissol , Emmanuelle Bompas , Antoine Italiano , Nicolas Isambert , Corinne Delcambre-Lair , Nicolas Penel , François Bertucci , Cécile Guillemet , Julien Plenecassagnes , Stéphanie Foulon , Étienne Chatelut , Axel Le Cesne , Fabienne Thomas

Bintrafusp Alfa, a Bifunctional Fusion Protein Targeting TGF-β and PD-L1, in Patients with Esophageal Adenocarcinoma: Results from a Phase 1 Cohort.

Targeted oncology
Avec: Benjamin Tan , Adnan Khattak , Enriqueta Felip , Karen Kelly , Patricia Rich , Ding Wang , Christoph Helwig , Isabelle Dussault , Laureen S Ojalvo , Nicolas Isambert

Durvalumab compared to maintenance chemotherapy in metastatic breast cancer: the randomized phase II SAFIR02-BREAST IMMUNO trial.

Nature medicine
Avec: Thomas Bachelot , Thomas Filleron , Ivan Bieche , Monica Arnedos , Mario Campone , Florence Dalenc , Florence Coussy , Marie-Paule Sablin , Marc Debled , Claudia Lefeuvre-Plesse , Anthony Goncalves , Marie-Ange Mouret Reynier , William Jacot , Benoit You , Philippe Barthelemy , Benjamin Verret , Nicolas Isambert , Xavier Tchiknavorian , Christelle Levy , Jean-Christophe Thery , Tifenn L'Haridon , Jean-Marc Ferrero , Alice Mege , Francesco Del Piano , Etienne Rouleau , Alicia Tran-Dien , Julien Adam , Amelie Lusque , Marta Jimenez , Alexandra Jacquet , Ingrid Garberis , Fabrice Andre

Treatment of 120 adult osteosarcoma patients with metachronous and synchronous metastases: A retrospective series of the French Sarcoma Group.

International journal of cancer
Avec: Elise Lavit , Mihaela Aldea , Sophie Piperno-Neumann , Nelly Firmin , Antoine Italiano , Nicolas Isambert , Jean-Emmanuel Kurtz , Corinne Delcambre , Valérie Lebrun , Pauline Soibinet-Oudot , Christine Chevreau , Emmanuelle Bompas , Christine Le Maignan , Pascaline Boudou-Rouquette , Axel Le Cesne , Julien Mancini , Jean-Yves Blay , Florence Duffaud

A single-arm multicentre phase II trial of doxorubicin in combination with trabectedin in the first-line treatment for leiomyosarcoma with long-term follow-up and impact of cytoreductive surgery.

ESMO open
Avec: P Pautier , A Floquet , C Chevreau , N Penel , C Guillemet , C Delcambre , D Cupissol , F Selle , N Isambert , S Piperno-Neumann , E Saada-Bouzid , F Bertucci , E Bompas , J Alexandre , O Collard , V Lebrun-Ly , P Soulier , M Toulmonde , A Le Cesne , B Lacas , F Duffaud , Auteur inconnu

Heritable defects in telomere and mitotic function selectively predispose to sarcomas.

Science (New York, N.Y.)
Avec: Mandy L Ballinger , Swetansu Pattnaik , Piyushkumar A Mundra , Milita Zaheed , Emma Rath , Peter Priestley , Jonathan Baber , Isabelle Ray-Coquard , Nicholas Isambert , Sylvain Causeret , Winette T A van der Graaf , Ajay Puri , Florence Duffaud , Axel Le Cesne , Beatrice Seddon , Coonoor Chandrasekar , Joshua D Schiffman , Andrew S Brohl , Paul A James , Jean-Emmanuel Kurtz , Nicolas Penel , Ola Myklebost , Leonardo A Meza-Zepeda , Hilda Pickett , Maya Kansara , Nicola Waddell , Olga Kondrashova , John V Pearson , Andrew P Barbour , Shuai Li , Tuong L Nguyen , Diane Fatkin , Robert M Graham , Eleni Giannoulatou , Melissa J Green , Warren Kaplan , Shyamsundar Ravishankar , Joseph Copty , Joseph E Powell , Edwin Cuppen , Kristel van Eijk , Jan Veldink , Jin-Hee Ahn , Jeong Eun Kim , R Lor Randall , Kathy Tucker , Ian Judson , Rajiv Sarin , Thomas Ludwig , Emmanuelle Genin , Jean-Francois Deleuze , Auteur inconnu , Michelle Haber , Glenn Marshall , Murray J Cairns , Jean-Yves Blay , Auteur inconnu , David M Thomas , Martin Tattersall , Susan Neuhaus , Craig Lewis , Kathy Tucker , Richard Carey-Smith , David Wood , Sandro Porceddu , Ian Dickinson , Heather Thorne , Paul James , Isabelle Ray-Coquard , Jean-Yves Blay , Philippe Cassier , Axel Le Cesne , Florence Duffaud , Nicolas Penel , Nicolas Isambert , Jean-Emmanuel Kurtz , Ajay Puri , Rajiv Sarin , Jin-Hee Ahn , Jeong Eun Kim , Iain Ward , Ian Judson , Winette van der Graaf , Beatrice Seddon , Coonoor Chandrasekar , Rory Rickar , Ivo Hennig , Joshua Schiffman , R Lor Randall , Audrey Silvestri , Anaiis Zaratzian , Michael Tayao , Kelly Walwyn , Eveline Niedermayr , Denia Mang , Richard Clark , Tina Thorpe , Jessica MacDonald , Kim Riddell , Jasmine Mar , Vicki Fennelly , Allison Wicht , Belinda Zielony , Emma Galligan , Genna Glavich , Johanna Stoeckert , Lynda Williams , Lana Djandjgava , Iwona Buettner , Carla Osinki , Sonya Stephens , Muriel Rogasik , Laure Bouclier , Magali Girodet , Amandine Charreton , Yohan Fayet , Saniya Crasto , Bhanupriya Sandupatla , Yeon Yoon , Noda Je , Liz Thompson , Trent Fowler , Bella Johnson , Galina Petrikova , Thomas Hambridge , Angela Hutchins , Diego Bottero , Deborah Scanlon , Jo Stokes-Denson , Emmanuelle Génin , Dominique Campion , Jean-François Dartigues , Jean-François Deleuze , Jean-Charles Lambert , Richard Redon , Thomas Ludwig , Benjamin Grenier-Boley , Sébastien Letort , Pierre Lindenbaum , Vincent Meyer , Olivier Quenez , Christian Dina , Céline Bellenguez , Camille Charbonnier Le Clézio , Joanna Giemza , Stéphanie Chatel , Claude Férec , Hervé Le Marec , Luc Letenneur , Gaël Nicolas , Karen Rouault

Identification of

Frontiers in oncology
Avec: Alexander Spira , Ahmad Awada , Nicolas Isambert , David Lorente , Nicolas Penel , Yue Zhang , Laureen S Ojalvo , Christine Hicking , P Alexander Rolfe , Christian Ihling , Isabelle Dussault , George Locke , Christian Borel

Impact of Metastasis Surgery and Alkylating-Agent-Based Chemotherapy on Outcomes of Metastatic Malignant Phyllodes Tumors: A Multicenter Retrospective Study.

Annals of surgical oncology
Avec: Mathias Neron , Christophe Sajous , Simon Thezenas , Sophie Piperno-Neumann , Fabien Reyal , Marick Laé , Camille Chakiba , Nicolas Penel , Thomas Ryckewaert , Charles Honoré , François Bertucci , Audrey Monneur , Sébastien Salas , Florence Duffaud , Esma Saada-Bouzid , Nicolas Isambert , Mehdi Brahmi , Isabelle Ray-Coquard , Jean-Yves Blay , Nelly Firmin , Auteur inconnu

Health-related quality of life as an endpoint in oncology phase I trials: a systematic review.

BMC cancer
Avec: Frédéric Fiteni , Isabelle Le Ray , Ahmad Ousmen , Nicolas Isambert , Amélie Anota , Franck Bonnetain

Prognostic value of transcriptomic determination of tumour-infiltrating lymphocytes in localised breast cancer.

European journal of cancer (Oxford, England : 1990)
Avec: Caroline Truntzer , Nicolas Isambert , Laurent Arnould , Sylvain Ladoire , Francois Ghiringhelli

Sarcomas in patients over 90: Natural history and treatment-A nationwide study over 6 years.

International journal of cancer
Avec: Clémence Basse , Antoine Italiano , Nicolas Penel , Olivier Mir , Claire Chemin , Maud Toulmonde , Florence Duffaud , Axel Le Cesne , Christine Chevreau , Carlos Maynou , Philippe Anract , François Gouin , Maria Rios , Nelly Firmin , Jean-Emmanuel Kurtz , Pierre Kerbrat , Sophie Piperno-Neumann , François Bertucci , Philippe Rosset , Nicolas Isambert , Emmanuelle Bompas , Pascale Dubray-Longeras , Fabrice Fiorenza , Christine Le Maignan , Loïc Chaigneau , Antoine Thyss , Olivier Bouché , Jean-Christophe Eymard , Corinne Delcambre Lair , Julien Adam , Marie Karanian , Céleste Lebbé , Aurélien Dupré , Pierre Meeus , Mehdi Brahmi , Armelle Dufresne , Françoise Ducimetière , Isabelle Ray-Coquard , Jean-Yves Blay

Membrane-bound exosomal HSP70 as a biomarker for detection and monitoring of malignant solid tumours: a pilot study.

Pilot and feasibility studies
Avec: Gaétan Chanteloup , Marine Cordonnier , Nicolas Isambert , Aurélie Bertaut , Guillaume Marcion , Carmen Garrido , Jessica Gobbo

Long-term efficacy update of crizotinib in patients with advanced, inoperable inflammatory myofibroblastic tumour from EORTC trial 90101 CREATE.

European journal of cancer (Oxford, England : 1990)
Avec: Patrick Schöffski , Michaela Kubickova , Agnieszka Wozniak , Jean-Yves Blay , Sandra J Strauss , Silvia Stacchiotti , Tomasz Switaj , Veit Bücklein , Michael G Leahy , Antoine Italiano , Nicolas Isambert , Maria Debiec-Rychter , Raf Sciot , Che-Jui Lee , Frank M Speetjens , Axelle Nzokirantevye , Anouk Neven , Bernd Kasper

Phase I Study of Lysine-Specific Demethylase 1 Inhibitor, CC-90011, in Patients with Advanced Solid Tumors and Relapsed/Refractory Non-Hodgkin Lymphoma.

Clinical cancer research : an official journal of the American Association for Cancer Research
Avec: Antoine Hollebecque , Stefania Salvagni , Ruth Plummer , Nicolas Isambert , Patricia Niccoli , Jaume Capdevila , Giuseppe Curigliano , Victor Moreno , Patricia Martin-Romano , Eric Baudin , Marina Arias , Sheila Mora , Juan de Alvaro , Jorge Di Martino , Josep L Parra-Palau , Tania Sánchez-Pérez , Ida Aronchik , Ellen H Filvaroff , Manisha Lamba , Zariana Nikolova , Johann S de Bono

Optimization of G-CSF dosing schedule in patients treated with eribulin: a modeling approach.

Cancer chemotherapy and pharmacology
Avec: Manon Reda , Pauline Macaire , Hélène Bellio , Lionel Uwer , Silvia Ilie , Véronique Lorgis , Audrey Hennequin , Sylvain Ladoire , Emilie Rederstorff , Pierre Fumoleau , Nicolas Isambert , Nathalie Bonnin , Benoit You , Gilles Freyer , Isabelle Desmoulins , Antonin Schmitt

Risk factors for biliary stent infections in malignant biliary obstruction secondary to unresectable malignancies.

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer
Avec: Sébastien Petit , Mathieu Puyade , Maxime Pichon , Marc Wangermez , Stéphane Velasco , France Roblot , Nicolas Isambert , Camille Evrard , Blandine Rammaert

Access to early-phase clinical trials in older patients with cancer in France: the EGALICAN-2 study.

ESMO open
Avec: C Baldini , E Charton , E Schultz , L Auroy , A Italiano , M Robert , E Coquan , N Isambert , P Moreau , S Le Gouill , C Le Tourneau , Z Ghrieb , J J Kiladjian , J P Delord , C Gomez Roca , N Vey , F Barlesi , T Lesimple , N Penel , J C Soria , C Massard , S Besle

Improved nationwide survival of sarcoma patients with a network of reference centers.

Annals of oncology : official journal of the European Society for Medical Oncology
Avec: J Y Blay , N Penel , T Valentin , Ph Anract , F Duffaud , A Dufresne , B Verret , A Cordoba , A Italiano , M Brahmi , C Henon , T Amouyel , I Ray-Coquard , G Ferron , P Boudou-Rouquette , C Tlemsani , S Salas , R Rochwerger , M Faron , E Bompas , A Ducassou , D Gangloff , F Gouin , N Firmin , S Piperno-Neumann , M Rios , M Ropars , J E Kurtz , L R Le Nail , F Bertucci , S Carrere , C Llacer , S Watson , S Bonvalot , A Leroux , C Perrin , J Gantzer , M Pracht , B Narciso , A Monneur , C Lebbe , A Hervieu , E Saada-Bouzid , P Dubray-Longeras , F Fiorenza , L Chaigneau , Z-M Nevieres , P Soibinet , O Bouché , C Guillemet , J P Spano , J C Ruzic , N Isambert , G Vaz , P Meeus , M Karanian , Carine Ngo , J M Coindre , G De Pinieux , F Le Loarer , F Ducimetiere , C Chemin , M Morelle , M Toulmonde , A Le Cesne

Low RNA disruption during neoadjuvant chemotherapy predicts pCR absence in patients with breast cancer.

JNCI cancer spectrum
Avec: Marina Elena Cazzaniga , Foluso Ademuyiwa , Thierry Petit , Joke Tio , Daniele Generali , Eva M Ciruelos , Nadia Califaretti , Brigitte Poirier , Antonio Ardizzoia , Arnd Hoenig , Benno Lex , Marie-Ange Mouret-Reynier , Dagmar Giesecke , Nicolas Isambert , Ricardo Masetti , Lacey Pitre , Denise Wrobel , Paule Augereau , Manuela Milani , Sara Rask , Christine Solbach , Laura Pritzker , Sanaa Noubir , Amadeo Parissenti , Maureen Trudeau

Doxorubicin alone versus doxorubicin with trabectedin followed by trabectedin alone as first-line therapy for metastatic or unresectable leiomyosarcoma (LMS-04): a randomised, multicentre, open-label phase 3 trial.

The Lancet. Oncology
Avec: Patricia Pautier , Antoine Italiano , Sophie Piperno-Neumann , Christine Chevreau , Nicolas Penel , Nelly Firmin , Pascaline Boudou-Rouquette , François Bertucci , Corinne Balleyguier , Valérie Lebrun-Ly , Isabelle Ray-Coquard , Elsa Kalbacher , Aurélie Bardet , Emmanuelle Bompas , Olivier Collard , Nicolas Isambert , Cécile Guillemet , Maria Rios , Baptiste Archambaud , Florence Duffaud , Auteur inconnu

Real-World Experience of Efficacy and Safety of Trabectedin in Patients with Soft Tissue Sarcoma: A Bicentric Retrospective Analysis.

Oncology
Avec: Loïc Chaigneau , Marine Jary , Virginie Nerich , Alice Hervieu , Sébastien Aubry , Céline Charon Barra , Guillaume Meynard , Florent Neumann , Elsa Kalbacher , Nicolas Isambert

Epithelioid hemangio-endothelioma (EHE) in NETSARC: The nationwide series of 267 patients over 12 years.

European journal of cancer (Oxford, England : 1990)
Avec: J Y Blay , S Piperno-Neumann , S Watson , A Dufresne , T Valentin , F Duffaud , M Toulmonde , A Italiano , F Bertucci , C Tlemsani , N Firmin , E Bompas , C Perrin , M Ropars , E Saada-Bouzid , P Dubray-Longeras , A Hervieu , C Lebbe , J Gantzer , L Chaigneau , F Fiorenza , M Rios , N Isambert , P Soibinet , P Boudou-Roquette , B Verret , G Ferron , T Ryckewaert , L Lebellec , M Brahmi , F Gouin , P Meeus , G Vaz , F Le Loarer , M Karanian , G De Pinieux , F Ducimetiere , C Chemin , M Morelle , A Le Cesne , N Penel , Auteur inconnu

Paclitaxel plus carboplatin and durvalumab with or without oleclumab for women with previously untreated locally advanced or metastatic triple-negative breast cancer: the randomized SYNERGY phase I/II trial.

Nature communications
Avec: Laurence Buisseret , Delphine Loirat , Philippe Aftimos , Christian Maurer , Kevin Punie , Véronique Debien , Paulus Kristanto , Daniel Eiger , Anthony Goncalves , François Ghiringhelli , Donatienne Taylor , Florent Clatot , Tom Van den Mooter , Jean-Marc Ferrero , Hervé Bonnefoi , Jean-Luc Canon , Francois P Duhoux , Laura Mansi , Renaud Poncin , Philippe Barthélémy , Nicolas Isambert , Zoë Denis , Xavier Catteau , Roberto Salgado , Elisa Agostinetto , Evandro de Azambuja , Françoise Rothé , Ligia Craciun , David Venet , Emanuela Romano , John Stagg , Marianne Paesmans , Denis Larsimont , Christos Sotiriou , Michail Ignatiadis , Martine Piccart-Gebhart

Réseau de co-auteurs

Nicolas Isambert 46 collaborations
Nicolas Penel 17 collaborations
Jean-Yves Blay 13 collaborations
Florence Duffaud 12 collaborations
François Bertucci 10 collaborations
Antoine Italiano 10 collaborations
Isabelle Ray-Coquard 10 collaborations
Emmanuelle Bompas 10 collaborations
None None 10 collaborations
N Isambert 9 collaborations
Sophie Piperno-Neumann 9 collaborations
Axel Le Cesne 9 collaborations
Christine Chevreau 8 collaborations
N Penel 7 collaborations
A Italiano 6 collaborations
Nelly Firmin 6 collaborations
E Bompas 5 collaborations
F Bertucci 5 collaborations
S Piperno-Neumann 5 collaborations
Benoit You 5 collaborations
Pascaline Boudou-Rouquette 5 collaborations
Elsa Kalbacher 5 collaborations
Jean-Emmanuel Kurtz 5 collaborations
C Guillemet 4 collaborations
M Rios 4 collaborations
F Duffaud 4 collaborations
Florence Dalenc 4 collaborations
Olivier Collard 4 collaborations
Cécile Guillemet 4 collaborations
Maud Toulmonde 4 collaborations
Olivier Mir 4 collaborations
Esma Saada-Bouzid 4 collaborations
Aurélie Bertaut 4 collaborations
Sylvain Causeret 4 collaborations
A Le Cesne 4 collaborations
Laureen S Ojalvo 4 collaborations
I Ray-Coquard 3 collaborations
C Delcambre 3 collaborations
C Chevreau 3 collaborations
D Cupissol 3 collaborations
Christelle Levy 3 collaborations
Renaud Sabatier 3 collaborations
C Le Tourneau 3 collaborations
Patricia Pautier 3 collaborations
Maria Rios 3 collaborations
Beatrice Seddon 3 collaborations
François Le Loarer 3 collaborations
Laure Favier 3 collaborations
Anthony Goncalves 3 collaborations
L Chaigneau 3 collaborations
Alice Hervieu 3 collaborations
Alain Ravaud 3 collaborations
Loïc Chaigneau 3 collaborations
Jean-Marc Ferrero 3 collaborations
Christoph Helwig 3 collaborations
Sylvain Ladoire 3 collaborations
E Saada-Bouzid 3 collaborations
M Toulmonde 3 collaborations
P Pautier 2 collaborations
J-O Bay 2 collaborations
Patrick Sfumato 2 collaborations
Marie Robert 2 collaborations
Keyvan Rezai 2 collaborations
Séverine Garnier 2 collaborations
Arnaud Guille 2 collaborations
Nadine Carbuccia 2 collaborations
Max Chaffanet 2 collaborations
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Anthony Gonçalves 2 collaborations
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Carlo Lucchesi 2 collaborations
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Maud Kamal 2 collaborations
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S Salas 2 collaborations
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Christian Rolfo 2 collaborations
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E Charton 2 collaborations
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B Verret 2 collaborations
M Brahmi 2 collaborations
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C Tlemsani 2 collaborations
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M Ropars 2 collaborations
S Watson 2 collaborations
C Perrin 2 collaborations
J Gantzer 2 collaborations
C Lebbe 2 collaborations
A Hervieu 2 collaborations
P Dubray-Longeras 2 collaborations
F Fiorenza 2 collaborations
P Soibinet 2 collaborations
G Vaz 2 collaborations
P Meeus 2 collaborations
M Karanian 2 collaborations
G De Pinieux 2 collaborations
F Le Loarer 2 collaborations
F Ducimetiere 2 collaborations
C Chemin 2 collaborations
M Morelle 2 collaborations
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