R Lappano

Affiliations

Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036, Rende, Italy.

Publications (39)

Newly Synthesized Imino-Derivatives Analogues of Resveratrol Exert Inhibitory Effects in Breast Tumor Cells.

International journal of molecular sciences

Avec: Domenico Iacopetta , Rosamaria Lappano , Annaluisa Mariconda , Jessica Ceramella , Maria Stefania Sinicropi , Carmela Saturnino , Marianna Talia , Francesca Cirillo , Fabio Martinelli , Francesco Puoci , Camillo Rosano , Pasquale Longo , Marcello Maggiolini

Activation of the S100A7/RAGE Pathway by IGF-1 Contributes to Angiogenesis in Breast Cancer.

Cancers

Avec: Maria Grazia Muoio , Marianna Talia , Rosamaria Lappano , Andrew H Sims , Veronica Vella , Francesca Cirillo , Livia Manzella , Marika Giuliano , Marcello Maggiolini , Antonino Belfiore , Ernestina Marianna De Francesco

Focal adhesion kinase (FAK) activation by estrogens involves GPER in triple-negative breast cancer cells.

Journal of experimental & clinical cancer research : CR

Avec: Damiano Cosimo Rigiracciolo , Maria Francesca Santolla , Rosamaria Lappano , Adele Vivacqua , Francesca Cirillo , Giulia Raffaella Galli , Marianna Talia , Lucia Muglia , Michele Pellegrino , Nijiro Nohata , Maria Teresa Di Martino , Marcello Maggiolini

A Biocompatible Aspartic-Decorated Metal-Organic Framework with Tubular Motif Degradable under Physiological Conditions.

Inorganic chemistry

Avec: Marta Mon , Rosaria Bruno , Rosamaria Lappano , Marcello Maggiolini , Leonardo Di Donna , Jesus Ferrando Soria , Donatella Armentano , Emilio Pardo

Estrogen receptor variant ERα46 and insulin receptor drive in primary breast cancer cells growth effects and interleukin 11 induction prompting the motility of cancer-associated fibroblasts.

Clinical and translational medicine

Avec: Francesca Cirillo , Michele Pellegrino , Marianna Talia , Ida Daniela Perrotta , Damiano Cosimo Rigiracciolo , Asia Spinelli , Domenica Scordamaglia , Lucia Muglia , Rita Guzzi , Anna Maria Miglietta , Ernestina Marianna De Francesco , Antonino Belfiore , Marcello Maggiolini , Rosamaria Lappano

Multifaceted Interplay between Hormones, Growth Factors and Hypoxia in the Tumor Microenvironment.

Cancers

Avec: Rosamaria Lappano , Lauren A Todd , Mia Stanic , Qi Cai , Marcello Maggiolini , Francesco Marincola , Violena Pietrobon

RAGE inhibition blunts insulin-induced oncogenic signals in breast cancer.

Breast cancer research : BCR

Avec: M G Muoio , M Pellegrino , V Rapicavoli , M Talia , G Scavo , V Sergi , V Vella , S Pettinato , M G Galasso , R Lappano , D Scordamaglia , F Cirillo , A Pulvirenti , D C Rigiracciolo , M Maggiolini , A Belfiore , E M De Francesco

Mitochondrial transfer from Adipose stem cells to breast cancer cells drives multi-drug resistance.

Journal of experimental & clinical cancer research : CR

Avec: Vitale Del Vecchio , Ayesha Rehman , Sameer Kumar Panda , Martina Torsiello , Martina Marigliano , Maria Maddalena Nicoletti , Giuseppe Andrea Ferraro , Vincenzo De Falco , Rosamaria Lappano , Eva Lieto , Francesca Pagliuca , Carlo Caputo , Marcella La Noce , Gianpaolo Papaccio , Virginia Tirino , Nirmal Robinson , Vincenzo Desiderio , Federica Papaccio

DDR1 regulates thyroid cancer cell differentiation via IGF-2/IR-A autocrine signaling loop.

Endocrine-related cancer

Avec: Veronica Vella , Maria Luisa Nicolosi , Patrizia Cantafio , Michele Massimino , Rosamaria Lappano , Paolo Vigneri , Roberto Ciuni , Pietro Gangemi , Andrea Morrione , Roberta Malaguarnera , Antonino Belfiore

IGF-1/IGF-1R/FAK/YAP Transduction Signaling Prompts Growth Effects in Triple-Negative Breast Cancer (TNBC) Cells.

Cells

Avec: Damiano Cosimo Rigiracciolo , Nijiro Nohata , Rosamaria Lappano , Francesca Cirillo , Marianna Talia , Domenica Scordamaglia , J Silvio Gutkind , Marcello Maggiolini

The Peptide ERα17p Is a GPER Inverse Agonist that Exerts Antiproliferative Effects in Breast Cancer Cells.

Cells

Avec: Rosamaria Lappano , Christophe Mallet , Bruno Rizzuti , Fedora Grande , Giulia Raffaella Galli , Cillian Byrne , Isabelle Broutin , Ludivine Boudieu , Alain Eschalier , Yves Jacquot , Marcello Maggiolini

Focal Adhesion Kinase Fine Tunes Multifaced Signals toward Breast Cancer Progression.

Cancers

Avec: Damiano Cosimo Rigiracciolo , Francesca Cirillo , Marianna Talia , Lucia Muglia , Jorge Silvio Gutkind , Marcello Maggiolini , Rosamaria Lappano

DDR1 Affects Metabolic Reprogramming in Breast Cancer Cells by Cross-Talking to the Insulin/IGF System.

Biomolecules

Avec: Veronica Vella , Marika Giuliano , Maria Luisa Nicolosi , Maria Giovanna Majorana , Małgorzata Anna Marć , Maria Grazia Muoio , Andrea Morrione , Marcello Maggiolini , Rosamaria Lappano , Ernestina Marianna De Francesco , Antonino Belfiore

Metformin counteracts stimulatory effects induced by insulin in primary breast cancer cells.

Journal of translational medicine

Avec: Domenica Scordamaglia , Francesca Cirillo , Marianna Talia , Maria Francesca Santolla , Damiano Cosimo Rigiracciolo , Lucia Muglia , Azzurra Zicarelli , Salvatore De Rosis , Francesca Giordano , Anna Maria Miglietta , Ernestina Marianna De Francesco , Veronica Vella , Antonino Belfiore , Rosamaria Lappano , Marcello Maggiolini

The Ephrin tyrosine kinase a3 (EphA3) is a novel mediator of RAGE-prompted motility of breast cancer cells.

Journal of experimental & clinical cancer research : CR

Avec: Marianna Talia , Francesca Cirillo , Asia Spinelli , Azzurra Zicarelli , Domenica Scordamaglia , Lucia Muglia , Salvatore De Rosis , Damiano Cosimo Rigiracciolo , Gianfranco Filippelli , Ida Daniela Perrotta , Mariano Davoli , Rosanna De Rosa , Rachele Macirella , Elvira Brunelli , Anna Maria Miglietta , Bruno Nardo , Daniela Tosoni , Salvatore Pece , Ernestina Marianna De Francesco , Antonino Belfiore , Marcello Maggiolini , Rosamaria Lappano

The G Protein Estrogen Receptor (GPER) is involved in the resistance to the CDK4/6 inhibitor palbociclib in breast cancer.

Journal of experimental & clinical cancer research : CR

Avec: Marianna Talia , Francesca Cirillo , Domenica Scordamaglia , Marika Di Dio , Azzurra Zicarelli , Salvatore De Rosis , Anna Maria Miglietta , Carlo Capalbo , Ernestina Marianna De Francesco , Antonino Belfiore , Fedora Grande , Bruno Rizzuti , Maria Antonietta Occhiuzzi , Giancarlo Fortino , Antonella Guzzo , Gianluigi Greco , Marcello Maggiolini , Rosamaria Lappano

Microenvironmental Determinants of Breast Cancer Metastasis: Focus on the Crucial Interplay Between Estrogen and Insulin/Insulin-Like Growth Factor Signaling.

Frontiers in cell and developmental biology

Avec: Veronica Vella , Ernestina Marianna De Francesco , Rosamaria Lappano , Maria Grazia Muoio , Livia Manzella , Marcello Maggiolini , Antonino Belfiore

Correction: Rigiracciolo, D.C., et al., IGF-1/IGF-1R/FAK/YAP Transduction Signaling Prompts Growth Effects in Triple-Negative Breast Cancer (TNBC) Cells.

Cells

Avec: Damiano Cosimo Rigiracciolo , Nijiro Nohata , Rosamaria Lappano , Francesca Cirillo , Marianna Talia , Domenica Scordamaglia , J Silvio Gutkind , Marcello Maggiolini

A Review on the Antimicrobial Activity of Schiff Bases: Data Collection and Recent Studies.

Antibiotics (Basel, Switzerland)

Avec: Jessica Ceramella , Domenico Iacopetta , Alessia Catalano , Francesca Cirillo , Rosamaria Lappano , Maria Stefania Sinicropi

Triple-negative breast cancer drug resistance, durable efficacy, and cure: how advanced biological insights and emerging drug modalities could transform progress.

Expert opinion on therapeutic targets

Avec: Ernestina Marianna De Francesco , Francesca Cirillo , Veronica Vella , Antonino Belfiore , Marcello Maggiolini , Rosamaria Lappano

IFN-I signaling in cancer: the connection with dysregulated Insulin/IGF axis.

Trends in endocrinology and metabolism: TEM

Avec: Veronica Vella , Ernestina Marianna De Francesco , Eduardo Bonavita , Rosamaria Lappano , Antonino Belfiore

Estetrol/GPER/SERPINB2 transduction signaling inhibits the motility of triple-negative breast cancer cells.

Journal of translational medicine

Avec: Francesca Cirillo , Asia Spinelli , Marianna Talia , Domenica Scordamaglia , Maria Francesca Santolla , Fedora Grande , Bruno Rizzuti , Marcello Maggiolini , Céline Gérard , Rosamaria Lappano

The AGEs/RAGE Transduction Signaling Prompts IL-8/CXCR1/2-Mediated Interaction between Cancer-Associated Fibroblasts (CAFs) and Breast Cancer Cells.

Cells

Avec: Maria Francesca Santolla , Marianna Talia , Francesca Cirillo , Domenica Scordamaglia , Salvatore De Rosis , Asia Spinelli , Anna Maria Miglietta , Bruno Nardo , Gianfranco Filippelli , Ernestina Marianna De Francesco , Antonino Belfiore , Rosamaria Lappano , Marcello Maggiolini

Insulin/IGF Axis and the Receptor for Advanced Glycation End Products: Role in Meta-inflammation and Potential in Cancer Therapy.

Endocrine reviews

Avec: Veronica Vella , Rosamaria Lappano , Eduardo Bonavita , Marcello Maggiolini , Robert Bryan Clarke , Antonino Belfiore , Ernestina Marianna De Francesco

Promising Perspectives of the Antiproliferative GPER Inverse Agonist ERα17p in Breast Cancer.

Cells

Avec: Marilena Kampa , Rosamaria Lappano , Fedora Grande , Bruno Rizzuti , Marcello Maggiolini , Elias Castanas , Yves Jacquot

GPER deletion triggers inhibitory effects in triple negative breast cancer (TNBC) cells through the JNK/c-Jun/p53/Noxa transduction pathway.

Cell death discovery

Avec: Francesca Cirillo , Marianna Talia , Maria Francesca Santolla , Michele Pellegrino , Domenica Scordamaglia , Asia Spinelli , Salvatore De Rosis , Francesca Giordano , Lucia Muglia , Azzurra Zicarelli , Marika Di Dio , Damiano Cosimo Rigiracciolo , Anna Maria Miglietta , Gianfranco Filippelli , Ernestina Marianna De Francesco , Antonino Belfiore , Rosamaria Lappano , Marcello Maggiolini

Dissecting CYP1A2 Activation by Arylalkanoic Acid Prodrugs toward the Development of Anti-Inflammatory Agents.

International journal of molecular sciences

Avec: Maria Antonietta Occhiuzzi , Giuseppina Ioele , Michele De Luca , Bruno Rizzuti , Domenica Scordamaglia , Rosamaria Lappano , Marcello Maggiolini , Antonio Garofalo , Fedora Grande

The IL1β-IL1R signaling is involved in the stimulatory effects triggered by hypoxia in breast cancer cells and cancer-associated fibroblasts (CAFs).

Journal of experimental & clinical cancer research : CR

Avec: Rosamaria Lappano , Marianna Talia , Francesca Cirillo , Damiano Cosimo Rigiracciolo , Domenica Scordamaglia , Rita Guzzi , Anna Maria Miglietta , Ernestina Marianna De Francesco , Antonino Belfiore , Andrew H Sims , Marcello Maggiolini

Computational Approaches for the Discovery of GPER Targeting Compounds.

Frontiers in endocrinology

Avec: Fedora Grande , Maria A Occhiuzzi , Rosamaria Lappano , Francesca Cirillo , Rita Guzzi , Antonio Garofalo , Yves Jacquot , Marcello Maggiolini , Bruno Rizzuti

Interaction of the Anti-Proliferative GPER Inverse Agonist ERα17p with the Breast Cancer Cell Plasma Membrane: From Biophysics to Biology.

Cells

Avec: Michaël Trichet , Rosamaria Lappano , Mathilde Belnou , Lilian Shadai Salazar Vazquez , Isabel Alves , Delphine Ravault , Sandrine Sagan , Lucie Khemtemourian , Marcello Maggiolini , Yves Jacquot

The G Protein-Coupled Estrogen Receptor (GPER) Expression Correlates with Pro-Metastatic Pathways in ER-Negative Breast Cancer: A Bioinformatics Analysis.

Cells

Avec: Marianna Talia , Ernestina Marianna De Francesco , Damiano Cosimo Rigiracciolo , Maria Grazia Muoio , Lucia Muglia , Antonino Belfiore , Marcello Maggiolini , Andrew H Sims , Rosamaria Lappano

GPER Mediates a Feedforward FGF2/FGFR1 Paracrine Activation Coupling CAFs to Cancer Cells toward Breast Tumor Progression.

Cells

Avec: Maria Francesca Santolla , Adele Vivacqua , Rosamaria Lappano , Damiano Cosimo Rigiracciolo , Francesca Cirillo , Giulia Raffaella Galli , Marianna Talia , Giuseppe Brunetti , Anna Maria Miglietta , Antonino Belfiore , Marcello Maggiolini

AHR and GPER mediate the stimulatory effects induced by 3-methylcholanthrene in breast cancer cells and cancer-associated fibroblasts (CAFs).

Journal of experimental & clinical cancer research : CR

Avec: Francesca Cirillo , Rosamaria Lappano , Leonardo Bruno , Bruno Rizzuti , Fedora Grande , Rita Guzzi , Sara Briguori , Anna Maria Miglietta , Miki Nakajima , Maria Teresa Di Martino , Marcello Maggiolini

Novel Mechanisms of Tumor Promotion by the Insulin Receptor Isoform A in Triple-Negative Breast Cancer Cells.

Cells

Avec: Veronica Vella , Marika Giuliano , Alessandro La Ferlita , Michele Pellegrino , Germano Gaudenzi , Salvatore Alaimo , Michele Massimino , Alfredo Pulvirenti , Alessandra Dicitore , Paolo Vigneri , Giovanni Vitale , Roberta Malaguarnera , Andrea Morrione , Andrew H Sims , Alfredo Ferro , Marcello Maggiolini , Rosamaria Lappano , Ernestina Marianna De Francesco , Antonino Belfiore

Focal Adhesion Kinase (FAK)-Hippo/YAP transduction signaling mediates the stimulatory effects exerted by S100A8/A9-RAGE system in triple-negative breast cancer (TNBC).

Journal of experimental & clinical cancer research : CR

Avec: Damiano Cosimo Rigiracciolo , Nijiro Nohata , Rosamaria Lappano , Francesca Cirillo , Marianna Talia , Sendi Rafael Adame-Garcia , Nadia Arang , Simone Lubrano , Ernestina Marianna De Francesco , Antonino Belfiore , J Silvio Gutkind , Marcello Maggiolini

Identification of a human estrogen receptor α tetrapeptidic fragment with dual antiproliferative and anti-nociceptive action.

Scientific reports

Avec: Baptiste Jouffre , Alexandre Acramel , Mathilde Belnou , Maria Francesca Santolla , Marianna Talia , Rosamaria Lappano , Fariba Nemati , Didier Decaudin , Lucie Khemtemourian , Wang-Qing Liu , Marcello Maggiolini , Alain Eschalier , Christophe Mallet , Yves Jacquot

IGF2: A Role in Metastasis and Tumor Evasion from Immune Surveillance?

Biomedicines

Avec: Antonino Belfiore , Rosaria Valentina Rapicavoli , Rosario Le Moli , Rosamaria Lappano , Andrea Morrione , Ernestina Marianna De Francesco , Veronica Vella

Role of the G Protein-Coupled Receptors in Cancer and Stromal Cells: From Functions to Novel Therapeutic Perspectives.

Cells

Avec: Rosamaria Lappano , Marcello Maggiolini

Cancer-associated fibroblasts (CAFs) gene signatures predict outcomes in breast and prostate tumor patients.

Journal of translational medicine

Avec: Marianna Talia , Eugenio Cesario , Francesca Cirillo , Domenica Scordamaglia , Marika Di Dio , Azzurra Zicarelli , Adelina Assunta Mondino , Maria Antonietta Occhiuzzi , Ernestina Marianna De Francesco , Antonino Belfiore , Anna Maria Miglietta , Michele Di Dio , Carlo Capalbo , Marcello Maggiolini , Rosamaria Lappano

Réseau de co-auteurs

Rosamaria Lappano 38 collaborations

Marcello Maggiolini 33 collaborations

Francesca Cirillo 21 collaborations

Antonino Belfiore 20 collaborations

Marianna Talia 19 collaborations

Ernestina Marianna De Francesco 18 collaborations

Damiano Cosimo Rigiracciolo 12 collaborations

Domenica Scordamaglia 12 collaborations

Veronica Vella 10 collaborations

Anna Maria Miglietta 10 collaborations

Maria Francesca Santolla 7 collaborations

Lucia Muglia 7 collaborations

Bruno Rizzuti 7 collaborations

Fedora Grande 7 collaborations

Asia Spinelli 5 collaborations

Yves Jacquot 5 collaborations

Azzurra Zicarelli 5 collaborations

Salvatore De Rosis 5 collaborations

Maria Grazia Muoio 4 collaborations

Andrew H Sims 4 collaborations

Michele Pellegrino 4 collaborations

Nijiro Nohata 4 collaborations

Rita Guzzi 4 collaborations

Andrea Morrione 4 collaborations

Marika Giuliano 3 collaborations

Giulia Raffaella Galli 3 collaborations

J Silvio Gutkind 3 collaborations

Gianfranco Filippelli 3 collaborations

Marika Di Dio 3 collaborations

Maria Antonietta Occhiuzzi 3 collaborations

Domenico Iacopetta 2 collaborations

Jessica Ceramella 2 collaborations

Maria Stefania Sinicropi 2 collaborations

Livia Manzella 2 collaborations

Adele Vivacqua 2 collaborations

Maria Teresa Di Martino 2 collaborations

Ida Daniela Perrotta 2 collaborations

Maria Luisa Nicolosi 2 collaborations

Michele Massimino 2 collaborations

Paolo Vigneri 2 collaborations

Roberta Malaguarnera 2 collaborations

Christophe Mallet 2 collaborations

Alain Eschalier 2 collaborations

Francesca Giordano 2 collaborations

Bruno Nardo 2 collaborations

Carlo Capalbo 2 collaborations

Eduardo Bonavita 2 collaborations

Antonio Garofalo 2 collaborations

Mathilde Belnou 2 collaborations

Lucie Khemtemourian 2 collaborations

Annaluisa Mariconda 1 collaboration

Carmela Saturnino 1 collaboration

Fabio Martinelli 1 collaboration

Francesco Puoci 1 collaboration

Camillo Rosano 1 collaboration

Pasquale Longo 1 collaboration

Marta Mon 1 collaboration

Rosaria Bruno 1 collaboration

Leonardo Di Donna 1 collaboration

Jesus Ferrando Soria 1 collaboration

Donatella Armentano 1 collaboration

Emilio Pardo 1 collaboration

Lauren A Todd 1 collaboration

Mia Stanic 1 collaboration

Qi Cai 1 collaboration

Francesco Marincola 1 collaboration

Violena Pietrobon 1 collaboration

M G Muoio 1 collaboration

M Pellegrino 1 collaboration

V Rapicavoli 1 collaboration

M Talia 1 collaboration

G Scavo 1 collaboration

V Sergi 1 collaboration

V Vella 1 collaboration

S Pettinato 1 collaboration

M G Galasso 1 collaboration

D Scordamaglia 1 collaboration

F Cirillo 1 collaboration

A Pulvirenti 1 collaboration

D C Rigiracciolo 1 collaboration

M Maggiolini 1 collaboration

A Belfiore 1 collaboration

E M De Francesco 1 collaboration

Vitale Del Vecchio 1 collaboration

Ayesha Rehman 1 collaboration

Sameer Kumar Panda 1 collaboration

Martina Torsiello 1 collaboration

Martina Marigliano 1 collaboration

Maria Maddalena Nicoletti 1 collaboration

Giuseppe Andrea Ferraro 1 collaboration

Vincenzo De Falco 1 collaboration

Eva Lieto 1 collaboration

Francesca Pagliuca 1 collaboration

Carlo Caputo 1 collaboration

Marcella La Noce 1 collaboration

Gianpaolo Papaccio 1 collaboration

Virginia Tirino 1 collaboration

Nirmal Robinson 1 collaboration

Vincenzo Desiderio 1 collaboration

Federica Papaccio 1 collaboration

Patrizia Cantafio 1 collaboration

Roberto Ciuni 1 collaboration

Pietro Gangemi 1 collaboration

Cillian Byrne 1 collaboration

Isabelle Broutin 1 collaboration

Ludivine Boudieu 1 collaboration

Jorge Silvio Gutkind 1 collaboration

Maria Giovanna Majorana 1 collaboration

Małgorzata Anna Marć 1 collaboration

Mariano Davoli 1 collaboration

Rosanna De Rosa 1 collaboration

Rachele Macirella 1 collaboration

Elvira Brunelli 1 collaboration

Daniela Tosoni 1 collaboration

Salvatore Pece 1 collaboration

Giancarlo Fortino 1 collaboration

Antonella Guzzo 1 collaboration

Gianluigi Greco 1 collaboration

Alessia Catalano 1 collaboration

Céline Gérard 1 collaboration

Robert Bryan Clarke 1 collaboration

Marilena Kampa 1 collaboration

Elias Castanas 1 collaboration

Giuseppina Ioele 1 collaboration

Michele De Luca 1 collaboration

Maria A Occhiuzzi 1 collaboration

Michaël Trichet 1 collaboration

Lilian Shadai Salazar Vazquez 1 collaboration

Isabel Alves 1 collaboration

Delphine Ravault 1 collaboration

Sandrine Sagan 1 collaboration

Giuseppe Brunetti 1 collaboration

Leonardo Bruno 1 collaboration

Sara Briguori 1 collaboration

Miki Nakajima 1 collaboration

Alessandro La Ferlita 1 collaboration

Germano Gaudenzi 1 collaboration

Salvatore Alaimo 1 collaboration

Alfredo Pulvirenti 1 collaboration

Alessandra Dicitore 1 collaboration

Giovanni Vitale 1 collaboration

Alfredo Ferro 1 collaboration

Sendi Rafael Adame-Garcia 1 collaboration

Nadia Arang 1 collaboration

Simone Lubrano 1 collaboration

Baptiste Jouffre 1 collaboration

Alexandre Acramel 1 collaboration

Fariba Nemati 1 collaboration

Didier Decaudin 1 collaboration

Wang-Qing Liu 1 collaboration

Rosaria Valentina Rapicavoli 1 collaboration

Rosario Le Moli 1 collaboration

Eugenio Cesario 1 collaboration

Adelina Assunta Mondino 1 collaboration

Michele Di Dio 1 collaboration