Roberta Bortolozzi

Affiliations

Istituto di Ricerca Pediatrica (IRP), Corso Stati Uniti 4, 35128, Padova, Italy.

Publications (26)

Developing novel classes of protein kinase CK1δ inhibitors by fusing [1,2,4]triazole with different bicyclic heteroaromatic systems.

European journal of medicinal chemistry

Avec: Ilenia Grieco , Maicol Bissaro , Davide Benedetto Tiz , Daniel I Perez , Conception Perez , Ana Martinez , Sara Redenti , Elena Mariotto , Roberta Bortolozzi , Giampietro Viola , Giorgio Cozza , Giampiero Spalluto , Stefano Moro , Stephanie Federico

Molecular and functional profiling of chemotolerant cells unveils nucleoside metabolism-dependent vulnerabilities in medulloblastoma.

Acta neuropathologica communications

Avec: Elena Mariotto , Elena Rampazzo , Roberta Bortolozzi , Fatlum Rruga , Ilaria Zeni , Lorenzo Manfreda , Chiara Marchioro , Martina Canton , Alice Cani , Ruben Magni , Alessandra Luchini , Silvia Bresolin , Giampietro Viola , Luca Persano

Identification of novel indole derivatives acting as inhibitors of the Keap1-Nrf2 interaction.

Journal of enzyme inhibition and medicinal chemistry

Avec: Barbara Cosimelli , Giovanni Greco , Sonia Laneri , Ettore Novellino , Antonia Sacchi , Giorgio Amendola , Sandro Cosconati , Roberta Bortolozzi , Giampietro Viola

Synthesis, in vitro and in vivo biological evaluation of substituted 3-(5-imidazo[2,1-b]thiazolylmethylene)-2-indolinones as new potent anticancer agents.

European journal of medicinal chemistry

Avec: Rita Morigi , Alessandra Locatelli , Alberto Leoni , Mirella Rambaldi , Roberta Bortolozzi , Elena Mattiuzzo , Roberto Ronca , Federica Maccarinelli , Ernest Hamel , Ruoli Bai , Andrea Brancale , Giampietro Viola

Pyrrolo[2',3':3,4]cyclohepta[1,2-

Journal of medicinal chemistry

Avec: Virginia Spanò , Roberta Rocca , Marilia Barreca , Daniele Giallombardo , Alessandra Montalbano , Anna Carbone , Maria Valeria Raimondi , Eugenio Gaudio , Roberta Bortolozzi , Ruoli Bai , Pierfrancesco Tassone , Stefano Alcaro , Ernest Hamel , Giampietro Viola , Francesco Bertoni , Paola Barraja

Synthesis, DNA-binding and antiproliferative properties of diarylquinolizinium derivatives.

Organic & biomolecular chemistry

Avec: Roberta Bortolozzi , Heiko Ihmels , Robin Schulte , Christopher Stremmel , Giampietro Viola

A facile synthesis of diaryl pyrroles led to the discovery of potent colchicine site antimitotic agents.

European journal of medicinal chemistry

Avec: Romeo Romagnoli , Paola Oliva , Maria Kimatrai Salvador , Stefano Manfredini , Chiara Padroni , Andrea Brancale , Salvatore Ferla , Ernest Hamel , Roberto Ronca , Federica Maccarinelli , Fatlum Rruga , Elena Mariotto , Giampietro Viola , Roberta Bortolozzi

Histone Deacetylase Inhibitors Impair Glioblastoma Cell Motility and Proliferation.

Cancers

Avec: Elena Rampazzo , Lorenzo Manfreda , Silvia Bresolin , Alice Cani , Elena Mariotto , Roberta Bortolozzi , Alessandro Della Puppa , Giampietro Viola , Luca Persano

Design, Synthesis and Biological Investigation of 2-Anilino Triazolopyrimidines as Tubulin Polymerization Inhibitors with Anticancer Activities.

Pharmaceuticals (Basel, Switzerland)

Avec: Romeo Romagnoli , Paola Oliva , Filippo Prencipe , Stefano Manfredini , Federica Budassi , Andrea Brancale , Salvatore Ferla , Ernest Hamel , Diana Corallo , Sanja Aveic , Lorenzo Manfreda , Elena Mariotto , Roberta Bortolozzi , Giampietro Viola

Surviving the hunger games: Metabolic reprogramming in medulloblastoma.

Biochemical pharmacology

Avec: Lorenzo Manfreda , Elena Rampazzo , Luca Persano , Giampietro Viola , Roberta Bortolozzi

Concise synthesis and biological evaluation of 2-Aryl-3-Anilinobenzo[b]thiophene derivatives as potent apoptosis-inducing agents.

Bioorganic chemistry

Avec: Romeo Romagnoli , Delia Preti , Ernest Hamel , Roberta Bortolozzi , Giampietro Viola , Andrea Brancale , Salvatore Ferla , Giampaolo Morciano , Paolo Pinton

Evaluating the effects of fluorine on biological properties and metabolic stability of some antitubulin 3-substituted 7-phenyl-pyrroloquinolinones.

European journal of medicinal chemistry

Avec: Roberta Bortolozzi , Davide Carta , Matteo Dal Prà , Giuseppe Antoniazzi , Elena Mattiuzzo , Mattia Sturlese , Veronica Di Paolo , Laura Calderan , Stefano Moro , Ernest Hamel , Luigi Quintieri , Roberto Ronca , Giampietro Viola , Maria Grazia Ferlin

Design, synthesis and biological evaluation of novel vicinal diaryl-substituted 1H-Pyrazole analogues of combretastatin A-4 as highly potent tubulin polymerization inhibitors.

European journal of medicinal chemistry

Avec: Romeo Romagnoli , Paola Oliva , Maria Kimatrai Salvador , Maria Encarnacion Camacho , Chiara Padroni , Andrea Brancale , Salvatore Ferla , Ernest Hamel , Roberto Ronca , Elisabetta Grillo , Roberta Bortolozzi , Fatlum Rruga , Elena Mariotto , Giampietro Viola

Design, synthesis, in vitro and in vivo biological evaluation of 2-amino-3-aroylbenzo[b]furan derivatives as highly potent tubulin polymerization inhibitors.

European journal of medicinal chemistry

Avec: Paola Oliva , Romeo Romagnoli , Stefano Manfredini , Andrea Brancale , Salvatore Ferla , Ernest Hamel , Roberto Ronca , Federica Maccarinelli , Arianna Giacomini , Fatlum Rruga , Elena Mariotto , Giampietro Viola , Roberta Bortolozzi

Design, synthesis and biological evaluation of 2-alkoxycarbonyl-3-anilinoindoles as a new class of potent inhibitors of tubulin polymerization.

Bioorganic chemistry

Avec: Romeo Romagnoli , Filippo Prencipe , Paola Oliva , Maria Kimatrai Salvador , Andrea Brancale , Salvatore Ferla , Ernest Hamel , Giampietro Viola , Roberta Bortolozzi , Leentje Persoons , Jan Balzarini , Sandra Liekens , Dominique Schols

Synthesis of 2H-Imidazo[2',1':2,3] [1,3]thiazolo[4,5-e]isoindol-8-yl-phenylureas with promising therapeutic features for the treatment of acute myeloid leukemia (AML) with FLT3/ITD mutations.

European journal of medicinal chemistry

Avec: Vincenzo Cilibrasi , Virginia Spanò , Roberta Bortolozzi , Marilia Barreca , Maria Valeria Raimondi , Roberta Rocca , Annalisa Maruca , Alessandra Montalbano , Stefano Alcaro , Roberto Ronca , Giampietro Viola , Paola Barraja

A first-in-class Wiskott-Aldrich syndrome protein activator with anti-tumor activity in hematologic cancers.

Haematologica

Avec: Filippo Spriano , Giulio Sartori , Jacopo Sgrignani , Laura Barnabei , Alberto J Arribas , Matilde Guala , Ana Maria Carrasco Del Amor , Meagan R Tomasso , Chiara Tarantelli , Luciano Cascione , Gaetanina Golino , Maria E Riveiro , Roberta Bortolozzi , Antonio Lupia , Francesco Paduano , Samuel Huguet , Keyvan Rezai , Andrea Rinaldi , Francesco Margheriti , Pedro Ventura , Greta Guarda , Giosuè Costa , Roberta Rocca , Alberto Furlan , Luuk M Verdonk , Paolo Innocenti , Nathaniel I Martin , Giampietro Viola , Christoph Driessen , Emanuele Zucca , Anastasios Stathis , Digvijay Gahtory , Maurits Van den Nieuwboer , Beat Bornhauser , Stefano Alcaro , Francesco Trapasso , Susana Cristobal , Shae B Padrick , Natalina Pazzi , Franco Cavalli , Andrea Cavalli , Eugenio Gaudio , Francesco Bertoni

Identification of pyrrolo[3',4':3,4]cyclohepta[1,2-d][1,2]oxazoles as promising new candidates for the treatment of lymphomas.

European journal of medicinal chemistry

Avec: Marilia Barreca , Virginia Spanò , Roberta Rocca , Roberta Bivacqua , Gianmarco Gualtieri , Maria Valeria Raimondi , Eugenio Gaudio , Roberta Bortolozzi , Lorenzo Manfreda , Ruoli Bai , Alessandra Montalbano , Stefano Alcaro , Ernest Hamel , Francesco Bertoni , Giampietro Viola , Paola Barraja

Design, synthesis, and biological investigation of selective human carbonic anhydrase II, IX, and XII inhibitors using 7-aryl/heteroaryl triazolopyrimidines bearing a sulfanilamide scaffold.

Journal of enzyme inhibition and medicinal chemistry

Avec: Romeo Romagnoli , Tiziano De Ventura , Stefano Manfredini , Erika Baldini , Claudiu T Supuran , Alessio Nocentini , Andrea Brancale , Roberta Bortolozzi , Lorenzo Manfreda , Giampietro Viola

Ecdysteroid Derivatives that Reverse P-Glycoprotein-Mediated Drug Resistance.

Journal of natural products

Avec: Roberta Bortolozzi , Andrea Luraghi , Elena Mattiuzzo , Alessandro Sacchetti , Alessandra Silvani , Giampietro Viola

Design, Synthesis, and Biological Evaluation of 6-Substituted Thieno[3,2- d]pyrimidine Analogues as Dual Epidermal Growth Factor Receptor Kinase and Microtubule Inhibitors.

Journal of medicinal chemistry

Avec: Romeo Romagnoli , Filippo Prencipe , Paola Oliva , Stefania Baraldi , Pier Giovanni Baraldi , Santiago Schiaffino Ortega , Mariem Chayah , Maria Kimatrai Salvador , Luisa Carlota Lopez-Cara , Andrea Brancale , Salvatore Ferla , Ernest Hamel , Roberto Ronca , Roberta Bortolozzi , Elena Mariotto , Elena Mattiuzzo , Giampietro Viola

Insight on [1,3]thiazolo[4,5-e]isoindoles as tubulin polymerization inhibitors.

European journal of medicinal chemistry

Avec: Virginia Spanò , Marilia Barreca , Roberta Rocca , Roberta Bortolozzi , Ruoli Bai , Anna Carbone , Maria Valeria Raimondi , Antonio Palumbo Piccionello , Alessandra Montalbano , Stefano Alcaro , Ernest Hamel , Giampietro Viola , Paola Barraja

Cinnamic acid derivatives linked to arylpiperazines as novel potent inhibitors of tyrosinase activity and melanin synthesis.

European journal of medicinal chemistry

Avec: Romeo Romagnoli , Paola Oliva , Filippo Prencipe , Stefano Manfredini , Maria Paola Germanò , Laura De Luca , Federico Ricci , Diana Corallo , Sanja Aveic , Elena Mariotto , Giampietro Viola , Roberta Bortolozzi

Synthesis and Biological Evaluation of Highly Active 7-Anilino Triazolopyrimidines as Potent Antimicrotubule Agents.

Pharmaceutics

Avec: Paola Oliva , Romeo Romagnoli , Barbara Cacciari , Stefano Manfredini , Chiara Padroni , Andrea Brancale , Salvatore Ferla , Ernest Hamel , Diana Corallo , Sanja Aveic , Noemi Milan , Elena Mariotto , Giampietro Viola , Roberta Bortolozzi

Identification of Homoharringtonine as a potent inhibitor of glioblastoma cell proliferation and migration.

Translational research : the journal of laboratory and clinical medicine

Avec: Elena Porcù , Francesca Maule , Lorenzo Manfreda , Elena Mariotto , Silvia Bresolin , Alice Cani , Roberta Bortolozzi , Alessandro Della Puppa , Diana Corallo , Giampietro Viola , Elena Rampazzo , Luca Persano

A Multi-Omics Approach Reveals Enrichment in Metabolites Involved in the Regulation of the Glutathione Pathway in LIN28B-Dependent Cancer Cells.

International journal of molecular sciences

Avec: Matteo Stocchero , Diana Corallo , Silvia Bresolin , Marcella Pantile , Paola Pirillo , Roberta Bortolozzi , Sara Menegazzo , Daniele Boso , Giampietro Viola , Eugenio Baraldi , Alessandra Biffi , Giuseppe Giordano , Sanja Aveic

Réseau de co-auteurs

Giampietro Viola 26 collaborations

Ernest Hamel 13 collaborations

Elena Mariotto 11 collaborations

Andrea Brancale 10 collaborations

Romeo Romagnoli 10 collaborations

Paola Oliva 8 collaborations

Salvatore Ferla 8 collaborations

Lorenzo Manfreda 7 collaborations

Roberto Ronca 7 collaborations

Stefano Manfredini 6 collaborations

Roberta Rocca 5 collaborations

Stefano Alcaro 5 collaborations

Diana Corallo 5 collaborations

Elena Rampazzo 4 collaborations

Fatlum Rruga 4 collaborations

Silvia Bresolin 4 collaborations

Luca Persano 4 collaborations

Elena Mattiuzzo 4 collaborations

Ruoli Bai 4 collaborations

Virginia Spanò 4 collaborations

Marilia Barreca 4 collaborations

Alessandra Montalbano 4 collaborations

Maria Valeria Raimondi 4 collaborations

Paola Barraja 4 collaborations

Maria Kimatrai Salvador 4 collaborations

Filippo Prencipe 4 collaborations

Sanja Aveic 4 collaborations

Alice Cani 3 collaborations

Federica Maccarinelli 3 collaborations

Eugenio Gaudio 3 collaborations

Francesco Bertoni 3 collaborations

Chiara Padroni 3 collaborations

Stefano Moro 2 collaborations

Anna Carbone 2 collaborations

Alessandro Della Puppa 2 collaborations

Ilenia Grieco 1 collaboration

Maicol Bissaro 1 collaboration

Davide Benedetto Tiz 1 collaboration

Daniel I Perez 1 collaboration

Conception Perez 1 collaboration

Ana Martinez 1 collaboration

Sara Redenti 1 collaboration

Giorgio Cozza 1 collaboration

Giampiero Spalluto 1 collaboration

Stephanie Federico 1 collaboration

Ilaria Zeni 1 collaboration

Chiara Marchioro 1 collaboration

Martina Canton 1 collaboration

Ruben Magni 1 collaboration

Alessandra Luchini 1 collaboration

Barbara Cosimelli 1 collaboration

Giovanni Greco 1 collaboration

Sonia Laneri 1 collaboration

Ettore Novellino 1 collaboration

Antonia Sacchi 1 collaboration

Giorgio Amendola 1 collaboration

Sandro Cosconati 1 collaboration

Rita Morigi 1 collaboration

Alessandra Locatelli 1 collaboration

Alberto Leoni 1 collaboration

Mirella Rambaldi 1 collaboration

Daniele Giallombardo 1 collaboration

Pierfrancesco Tassone 1 collaboration

Heiko Ihmels 1 collaboration

Robin Schulte 1 collaboration

Christopher Stremmel 1 collaboration

Federica Budassi 1 collaboration

Delia Preti 1 collaboration

Giampaolo Morciano 1 collaboration

Paolo Pinton 1 collaboration

Davide Carta 1 collaboration

Matteo Dal Prà 1 collaboration

Giuseppe Antoniazzi 1 collaboration

Mattia Sturlese 1 collaboration

Veronica Di Paolo 1 collaboration

Laura Calderan 1 collaboration

Luigi Quintieri 1 collaboration

Maria Grazia Ferlin 1 collaboration

Maria Encarnacion Camacho 1 collaboration

Elisabetta Grillo 1 collaboration

Arianna Giacomini 1 collaboration

Leentje Persoons 1 collaboration

Jan Balzarini 1 collaboration

Sandra Liekens 1 collaboration

Dominique Schols 1 collaboration

Vincenzo Cilibrasi 1 collaboration

Annalisa Maruca 1 collaboration

Filippo Spriano 1 collaboration

Giulio Sartori 1 collaboration

Jacopo Sgrignani 1 collaboration

Laura Barnabei 1 collaboration

Alberto J Arribas 1 collaboration

Matilde Guala 1 collaboration

Ana Maria Carrasco Del Amor 1 collaboration

Meagan R Tomasso 1 collaboration

Chiara Tarantelli 1 collaboration

Luciano Cascione 1 collaboration

Gaetanina Golino 1 collaboration

Maria E Riveiro 1 collaboration

Antonio Lupia 1 collaboration

Francesco Paduano 1 collaboration

Samuel Huguet 1 collaboration

Keyvan Rezai 1 collaboration

Andrea Rinaldi 1 collaboration

Francesco Margheriti 1 collaboration

Pedro Ventura 1 collaboration

Greta Guarda 1 collaboration

Giosuè Costa 1 collaboration

Alberto Furlan 1 collaboration

Luuk M Verdonk 1 collaboration

Paolo Innocenti 1 collaboration

Nathaniel I Martin 1 collaboration

Christoph Driessen 1 collaboration

Emanuele Zucca 1 collaboration

Anastasios Stathis 1 collaboration

Digvijay Gahtory 1 collaboration

Maurits Van den Nieuwboer 1 collaboration

Beat Bornhauser 1 collaboration

Francesco Trapasso 1 collaboration

Susana Cristobal 1 collaboration

Shae B Padrick 1 collaboration

Natalina Pazzi 1 collaboration

Franco Cavalli 1 collaboration

Andrea Cavalli 1 collaboration

Roberta Bivacqua 1 collaboration

Gianmarco Gualtieri 1 collaboration

Tiziano De Ventura 1 collaboration

Erika Baldini 1 collaboration

Claudiu T Supuran 1 collaboration

Alessio Nocentini 1 collaboration

Andrea Luraghi 1 collaboration

Alessandro Sacchetti 1 collaboration

Alessandra Silvani 1 collaboration

Stefania Baraldi 1 collaboration

Pier Giovanni Baraldi 1 collaboration

Santiago Schiaffino Ortega 1 collaboration

Mariem Chayah 1 collaboration

Luisa Carlota Lopez-Cara 1 collaboration

Antonio Palumbo Piccionello 1 collaboration

Maria Paola Germanò 1 collaboration

Laura De Luca 1 collaboration

Federico Ricci 1 collaboration

Barbara Cacciari 1 collaboration

Noemi Milan 1 collaboration

Elena Porcù 1 collaboration

Francesca Maule 1 collaboration

Matteo Stocchero 1 collaboration

Marcella Pantile 1 collaboration

Paola Pirillo 1 collaboration

Sara Menegazzo 1 collaboration

Daniele Boso 1 collaboration

Eugenio Baraldi 1 collaboration

Alessandra Biffi 1 collaboration

Giuseppe Giordano 1 collaboration