S Delignat

Affiliations

Institut National de la Santé et de la Recherche Médicale, Centre de Recherche des Cordeliers, Sorbonne Université, Université de Paris, Paris, France.

Publications (15)

The nitrone spin trap 5,5‑dimethyl‑1‑pyrroline N‑oxide binds to toll-like receptor-2-TIR-BB-loop domain and dampens downstream inflammatory signaling.

Biochimica et biophysica acta. Molecular basis of disease

Avec: Marcos D Muñoz , Lucas J Gutierrez , Sandrine Delignat , Jules Russick , Sandra E Gomez Mejiba , Sebastien Lacroix-Desmazes , Ricardo D Enriz , Dario C Ramirez

Removal of Mannose-Ending Glycan at Asn

Frontiers in immunology

Avec: Sandrine Delignat , Julie Rayes , Suryasarathi Dasgupta , Bagirath Gangadharan , Cécile V Denis , Olivier D Christophe , Jagadeesh Bayry , Srinivas V Kaveri , Sébastien Lacroix-Desmazes

Correction of bleeding in experimental severe hemophilia A by systemic delivery of factor VIII-encoding mRNA.

Haematologica

Avec: Jules Russick , Sandrine Delignat , Peter Milanov , Olivier Christophe , Gábor Boros , Cécile V Denis , Peter J Lenting , Srinivas V Kaveri , Sébastien Lacroix-Desmazes

Prevention of the anti-factor VIII memory B-cell response by inhibition of Bruton tyrosine kinase in experimental hemophilia A.

Haematologica

Avec: Sandrine Delignat , Jules Russick , Bagirath Gangadharan , Julie Rayes , Mathieu Ing , Jan Voorberg , Srinivas V Kaveri , Sébastien Lacroix-Desmazes

IVIg increases interleukin-11 levels, which in turn contribute to increased platelets, VWF and FVIII in mice and humans.

Clinical and experimental immunology

Avec: A Nguyen , Y Repesse , M Ebbo , Y Allenbach , O Benveniste , J M Vallat , L Magy , S Deshayes , G Maigné , H de Boysson , A Karnam , S Delignat , S Lacroix-Desmazes , J Bayry , A Aouba

Relevance of the Materno-Fetal Interface for the Induction of Antigen-Specific Immune Tolerance.

Frontiers in immunology

Avec: Angelina Mimoun , Sandrine Delignat , Ivan Peyron , Victoria Daventure , Maxime Lecerf , Jordan D Dimitrov , Srinivas V Kaveri , Jagadeesh Bayry , Sébastien Lacroix-Desmazes

The IgG-degrading enzyme, Imlifidase, restores the therapeutic activity of FVIII in inhibitor-positive hemophilia A mice.

Haematologica

Avec: Melissa Bou-Jaoudeh , Sandrine Delignat , Victoria Daventure , Jan Astermark , Hervé Lévesque , Jordan D Dimitrov , Claire Deligne , Valérie Proulle , Sébastien Lacroix-Desmazes

Transplacental delivery of therapeutic proteins by engineered immunoglobulin G: a step toward perinatal replacement therapy.

Journal of thrombosis and haemostasis : JTH

Avec: Angelina Mimoun , Melissa Bou-Jaoudeh , Sandrine Delignat , Victoria Daventure , Alejandra Reyes Ruiz , Maxime Lecerf , Aurélien Azam , Remi Noe , Ivan Peyron , Olivier D Christophe , Peter J Lenting , Valérie Proulle , Jenny McIntosh , Amit C Nathwani , Jordan D Dimitrov , Cécile V Denis , Sébastien Lacroix-Desmazes

Imlifidase, a new option to optimize the management of patients with hemophilia A on emicizumab.

Journal of thrombosis and haemostasis : JTH

Avec: Melissa Bou-Jaoudeh , Angelina Mimoun , Sandrine Delignat , Ivan Peyron , Ladislas Capdevila , Victoria Daventure , Claire Deligne , Jordan D Dimitrov , Olivier D Christophe , Cécile V Denis , Peter J Lenting , Valérie Proulle , Sébastien Lacroix-Desmazes

[Origin and nature of the neutralizing immune response against therapeutic factor VIII].

Medecine sciences : M/S

Avec: Mélissa Bou Jaoudeh , Sandrine Delignat , Aditi Varthaman , Sébastien Lacroix-Desmazes

IgG-cleaving endopeptidase enables in vivo gene therapy in the presence of anti-AAV neutralizing antibodies.

Nature medicine

Avec: Christian Leborgne , Elena Barbon , Jeffrey M Alexander , Hayley Hanby , Sandrine Delignat , Daniel M Cohen , Fanny Collaud , Saghana Muraleetharan , Dan Lupo , Joseph Silverberg , Karen Huang , Laetitia van Wittengerghe , Béatrice Marolleau , Adeline Miranda , Anna Fabiano , Victoria Daventure , Heena Beck , Xavier M Anguela , Giuseppe Ronzitti , Sean M Armour , Sebastien Lacroix-Desmazes , Federico Mingozzi

Stimulation with FITC-labeled antigens confers B cells with regulatory properties.

Cellular immunology

Avec: Cyril Planchais , Julie Rayes , Sandrine Delignat , Shina Pashova , Aditi Varthaman , Anastas Pashov , Jagadeesh Bayry , Srinivas V Kaveri , Jordan D Dimitrov , Sebastien Lacroix-Desmazes

Therapeutic normal IgG intravenous immunoglobulin activates Wnt-β-catenin pathway in dendritic cells.

Communications biology

Avec: Anupama Karnam , Naresh Rambabu , Mrinmoy Das , Melissa Bou-Jaoudeh , Sandrine Delignat , Fabian Käsermann , Sébastien Lacroix-Desmazes , Srini V Kaveri , Jagadeesh Bayry

Acquired Hemophilia A in IgG4-Related Disease: Case Report, Immunopathogenic Study, and Review of the Literature.

Frontiers in immunology

Avec: Sébastien Sanges , Emmanuelle Jeanpierre , Benjamin Lopez , Jules Russick , Sandrine Delignat , Benjamin Carpentier , Romain Dubois , Sylvain Dubucquoi , Thomas Guerrier , Éric Hachulla , Pierre-Yves Hatron , Camille Paris , Sophie Susen , David Launay , Sébastien Lacroix-Desmazes , Louis Terriou

High FVIII concentrations interfere with GPVI-mediated platelet activation in vitro.

Journal of thrombosis and haemostasis : JTH

Avec: Rohini Sekar , Angelina Mimoun , Melissa Bou-Jaoudeh , Stéphane Loyau , Sandrine Delignat , Victoria Daventure , Perrine Bonilla , Aishwarya Sudam Bahle , Krishnan Venkataraman , Julie Rayes , Yacine Boulaftali , Martine Jandrot-Perrus , Valérie Proulle , Sébastien Lacroix-Desmazes

Réseau de co-auteurs

Sandrine Delignat 14 collaborations

Sébastien Lacroix-Desmazes 11 collaborations

Victoria Daventure 6 collaborations

Srinivas V Kaveri 5 collaborations

Jordan D Dimitrov 5 collaborations

Melissa Bou-Jaoudeh 5 collaborations

Jules Russick 4 collaborations

Julie Rayes 4 collaborations

Cécile V Denis 4 collaborations

Jagadeesh Bayry 4 collaborations

Angelina Mimoun 4 collaborations

Valérie Proulle 4 collaborations

Sebastien Lacroix-Desmazes 3 collaborations

Olivier D Christophe 3 collaborations

Peter J Lenting 3 collaborations

Ivan Peyron 3 collaborations

Bagirath Gangadharan 2 collaborations

Maxime Lecerf 2 collaborations

Claire Deligne 2 collaborations

Aditi Varthaman 2 collaborations

Marcos D Muñoz 1 collaboration

Lucas J Gutierrez 1 collaboration

Sandra E Gomez Mejiba 1 collaboration

Ricardo D Enriz 1 collaboration

Dario C Ramirez 1 collaboration

Suryasarathi Dasgupta 1 collaboration

Peter Milanov 1 collaboration

Olivier Christophe 1 collaboration

Gábor Boros 1 collaboration

Mathieu Ing 1 collaboration

Jan Voorberg 1 collaboration

A Nguyen 1 collaboration

Y Repesse 1 collaboration

M Ebbo 1 collaboration

Y Allenbach 1 collaboration

O Benveniste 1 collaboration

J M Vallat 1 collaboration

L Magy 1 collaboration

S Deshayes 1 collaboration

G Maigné 1 collaboration

H de Boysson 1 collaboration

A Karnam 1 collaboration

S Lacroix-Desmazes 1 collaboration

J Bayry 1 collaboration

A Aouba 1 collaboration

Jan Astermark 1 collaboration

Hervé Lévesque 1 collaboration

Alejandra Reyes Ruiz 1 collaboration

Aurélien Azam 1 collaboration

Remi Noe 1 collaboration

Jenny McIntosh 1 collaboration

Amit C Nathwani 1 collaboration

Ladislas Capdevila 1 collaboration

Mélissa Bou Jaoudeh 1 collaboration

Christian Leborgne 1 collaboration

Elena Barbon 1 collaboration

Jeffrey M Alexander 1 collaboration

Hayley Hanby 1 collaboration

Daniel M Cohen 1 collaboration

Fanny Collaud 1 collaboration

Saghana Muraleetharan 1 collaboration

Dan Lupo 1 collaboration

Joseph Silverberg 1 collaboration

Karen Huang 1 collaboration

Laetitia van Wittengerghe 1 collaboration

Béatrice Marolleau 1 collaboration

Adeline Miranda 1 collaboration

Anna Fabiano 1 collaboration

Heena Beck 1 collaboration

Xavier M Anguela 1 collaboration

Giuseppe Ronzitti 1 collaboration

Sean M Armour 1 collaboration

Federico Mingozzi 1 collaboration

Cyril Planchais 1 collaboration

Shina Pashova 1 collaboration

Anastas Pashov 1 collaboration

Anupama Karnam 1 collaboration

Naresh Rambabu 1 collaboration

Mrinmoy Das 1 collaboration

Fabian Käsermann 1 collaboration

Srini V Kaveri 1 collaboration

Sébastien Sanges 1 collaboration

Emmanuelle Jeanpierre 1 collaboration

Benjamin Lopez 1 collaboration

Benjamin Carpentier 1 collaboration

Romain Dubois 1 collaboration

Sylvain Dubucquoi 1 collaboration

Thomas Guerrier 1 collaboration

Éric Hachulla 1 collaboration

Pierre-Yves Hatron 1 collaboration

Camille Paris 1 collaboration

Sophie Susen 1 collaboration

David Launay 1 collaboration

Louis Terriou 1 collaboration

Rohini Sekar 1 collaboration

Stéphane Loyau 1 collaboration

Perrine Bonilla 1 collaboration

Aishwarya Sudam Bahle 1 collaboration

Krishnan Venkataraman 1 collaboration

Yacine Boulaftali 1 collaboration

Martine Jandrot-Perrus 1 collaboration