Thomas Spangenberg

Affiliations

Global Health Institute of Merck , Ares Trading S.A., a subsidiary of Merck KGaA, Darmstadt, Germany , 1262 Eysins , Switzerland.

ORCID: 0000-0002-5654-8919

Publications (8)

Flexible 3D Cell-Based Platforms for the Discovery and Profiling of Novel Drugs Targeting

ACS infectious diseases

Avec: Francisca Arez , Sofia P Rebelo , Diana Fontinha , Daniel Simão , Tatiana R Martins , Marta Machado , Christoph Fischli , Claude Oeuvray , Lassina Badolo , Manuel J T Carrondo , Matthias Rottmann , Thomas Spangenberg , Catarina Brito , Beatrice Greco , Miguel Prudêncio , Paula M Alves

Preclinical Antimalarial Combination Study of M5717, a Plasmodium falciparum Elongation Factor 2 Inhibitor, and Pyronaridine, a Hemozoin Formation Inhibitor.

Antimicrobial agents and chemotherapy

Avec: Matthias Rottmann , Brian Jonat , Christin Gumpp , Satish K Dhingra , Marla J Giddins , Xiaoyan Yin , Lassina Badolo , Beatrice Greco , David A Fidock , Claude Oeuvray , Thomas Spangenberg

Setting Our Sights on Infectious Diseases.

ACS infectious diseases

Avec: Manu De Rycker , David Horn , Bree Aldridge , Richard K Amewu , Clifton E Barry , Frederick S Buckner , Sarah Cook , Michael A J Ferguson , Nathalie Gobeau , Jennifer Herrmann , Paul Herrling , William Hope , Jennifer Keiser , Maria Jose Lafuente-Monasterio , Paul D Leeson , Didier Leroy , Ujjini H Manjunatha , James McCarthy , Timothy J Miles , Valerie Mizrahi , Olena Moshynets , Jacquin Niles , John P Overington , John Pottage , Srinivasa P S Rao , Kevin D Read , Isabela Ribeiro , Lynn L Silver , Jen Southern , Thomas Spangenberg , Shyam Sundar , Caitlin Taylor , Wes Van Voorhis , Nicholas J White , Susan Wyllie , Paul G Wyatt , Ian H Gilbert

Efficacy and safety of ECG-synchronized pulsatile extracorporeal membrane oxygenation in the clinical setting: The SynCor Trial.

Artificial organs

Avec: Ingo Voigt , Tobias Spangenberg , Tareq Ibrahim , Christian Bradaric , Achim Viertel , Ezequiel Marcelo Tallone , Carsten Skurk , Peter Abel , Jochen Graf , Torsten Rinne , Jürgen Böhm , Alexander Ghanem , Christoph Liebetrau

Identification of hit compounds with anti-schistosomal activity on in vitro generated juvenile worms in cell-free medium.

PLoS neglected tropical diseases

Avec: Nermina Vejzagić , Ulrich Fabien Prodjinotho , Nagwa El-Khafif , Ruili Huang , Anton Simeonov , Thomas Spangenberg , Clarissa Prazeres da Costa

The Anthelmintic Activity of Praziquantel Analogs Correlates with Structure-Activity Relationships at TRPM

ACS medicinal chemistry letters

Avec: Daniel J Sprague , Marc Kaethner , Sang-Kyu Park , Claudia M Rohr , Jade L Harris , David Maillard , Thomas Spangenberg , Britta Lundström-Stadelmann , Jonathan S Marchant

Praziquantel Reduces Maternal Mortality and Offspring Morbidity by Enhancing Anti-Helminthic Immune Responses.

Frontiers in immunology

Avec: Matthew Lacorcia , Réka Kugyelka , Lorenz Spechtenhauser , Ulrich Fabien Prodjinotho , Youssef Hamway , Thomas Spangenberg , Clarissa Prazeres da Costa

Causal chemoprophylactic activity of cabamiquine against Plasmodium falciparum in a controlled human malaria infection: a randomised, double-blind, placebo-controlled study in the Netherlands.

The Lancet. Infectious diseases

Avec: Johan L van der Plas , Vincent P Kuiper , Wilhelmina M Bagchus , Matthias Bödding , Özkan Yalkinoglu , Aliona Tappert , Andrea Seitzinger , Thomas Spangenberg , Deon Bezuidenhout , Justin Wilkins , Claude Oeuvray , Satish K Dhingra , Vandana Thathy , David A Fidock , Lisanne C A Smidt , Geert V T Roozen , Jan Pieter R Koopman , Olivia A C Lamers , Jeroen Sijtsma , Roos van Schuijlenburg , Els Wessels , Pauline Meij , Ingrid M C Kamerling , Meta Roestenberg , Akash Khandelwal

Réseau de co-auteurs

Claude Oeuvray 3 collaborations

Lassina Badolo 2 collaborations

Matthias Rottmann 2 collaborations

Beatrice Greco 2 collaborations

Satish K Dhingra 2 collaborations

David A Fidock 2 collaborations

Ulrich Fabien Prodjinotho 2 collaborations

Clarissa Prazeres da Costa 2 collaborations

Francisca Arez 1 collaboration

Sofia P Rebelo 1 collaboration

Diana Fontinha 1 collaboration

Daniel Simão 1 collaboration

Tatiana R Martins 1 collaboration

Marta Machado 1 collaboration

Christoph Fischli 1 collaboration

Manuel J T Carrondo 1 collaboration

Catarina Brito 1 collaboration

Miguel Prudêncio 1 collaboration

Paula M Alves 1 collaboration

Brian Jonat 1 collaboration

Christin Gumpp 1 collaboration

Marla J Giddins 1 collaboration

Xiaoyan Yin 1 collaboration

Manu De Rycker 1 collaboration

David Horn 1 collaboration

Bree Aldridge 1 collaboration

Richard K Amewu 1 collaboration

Clifton E Barry 1 collaboration

Frederick S Buckner 1 collaboration

Sarah Cook 1 collaboration

Michael A J Ferguson 1 collaboration

Nathalie Gobeau 1 collaboration

Jennifer Herrmann 1 collaboration

Paul Herrling 1 collaboration

William Hope 1 collaboration

Jennifer Keiser 1 collaboration

Maria Jose Lafuente-Monasterio 1 collaboration

Paul D Leeson 1 collaboration

Didier Leroy 1 collaboration

Ujjini H Manjunatha 1 collaboration

James McCarthy 1 collaboration

Timothy J Miles 1 collaboration

Valerie Mizrahi 1 collaboration

Olena Moshynets 1 collaboration

Jacquin Niles 1 collaboration

John P Overington 1 collaboration

John Pottage 1 collaboration

Srinivasa P S Rao 1 collaboration

Kevin D Read 1 collaboration

Isabela Ribeiro 1 collaboration

Lynn L Silver 1 collaboration

Jen Southern 1 collaboration

Shyam Sundar 1 collaboration

Caitlin Taylor 1 collaboration

Wes Van Voorhis 1 collaboration

Nicholas J White 1 collaboration

Susan Wyllie 1 collaboration

Paul G Wyatt 1 collaboration

Ian H Gilbert 1 collaboration

Ingo Voigt 1 collaboration

Tobias Spangenberg 1 collaboration

Tareq Ibrahim 1 collaboration

Christian Bradaric 1 collaboration

Achim Viertel 1 collaboration

Ezequiel Marcelo Tallone 1 collaboration

Carsten Skurk 1 collaboration

Peter Abel 1 collaboration

Jochen Graf 1 collaboration

Torsten Rinne 1 collaboration

Jürgen Böhm 1 collaboration

Alexander Ghanem 1 collaboration

Christoph Liebetrau 1 collaboration

Nermina Vejzagić 1 collaboration

Nagwa El-Khafif 1 collaboration

Ruili Huang 1 collaboration

Anton Simeonov 1 collaboration

Daniel J Sprague 1 collaboration

Marc Kaethner 1 collaboration

Sang-Kyu Park 1 collaboration

Claudia M Rohr 1 collaboration

Jade L Harris 1 collaboration

David Maillard 1 collaboration

Britta Lundström-Stadelmann 1 collaboration

Jonathan S Marchant 1 collaboration

Matthew Lacorcia 1 collaboration

Réka Kugyelka 1 collaboration

Lorenz Spechtenhauser 1 collaboration

Youssef Hamway 1 collaboration

Johan L van der Plas 1 collaboration

Vincent P Kuiper 1 collaboration

Wilhelmina M Bagchus 1 collaboration

Matthias Bödding 1 collaboration

Özkan Yalkinoglu 1 collaboration

Aliona Tappert 1 collaboration

Andrea Seitzinger 1 collaboration

Deon Bezuidenhout 1 collaboration

Justin Wilkins 1 collaboration

Vandana Thathy 1 collaboration

Lisanne C A Smidt 1 collaboration

Geert V T Roozen 1 collaboration

Jan Pieter R Koopman 1 collaboration

Olivia A C Lamers 1 collaboration

Jeroen Sijtsma 1 collaboration

Roos van Schuijlenburg 1 collaboration

Els Wessels 1 collaboration

Pauline Meij 1 collaboration

Ingrid M C Kamerling 1 collaboration

Meta Roestenberg 1 collaboration

Akash Khandelwal 1 collaboration