Yoshihiko Tomofuji

Affiliations

Department of Immunology, Graduate School of Medicine and Faculty of Medicine, The University of Tokyo, Tokyo, Japan.

Publications (16)

Chd4 choreographs self-antigen expression for central immune tolerance.

Nature immunology

Avec: Yoshihiko Tomofuji , Hiroyuki Takaba , Hiroshi I Suzuki , Rayene Benlaribi , Cristian David Peña Martinez , Yoshihiro Abe , Yasuyuki Morishita , Tadashi Okamura , Akashi Taguchi , Tatsuhiko Kodama , Hiroshi Takayanagi

Whole gut virome analysis of 476 Japanese revealed a link between phage and autoimmune disease.

Annals of the rheumatic diseases

Avec: Yoshihiko Tomofuji , Toshihiro Kishikawa , Yuichi Maeda , Kotaro Ogawa , Takuro Nii , Tatsusada Okuno , Eri Oguro-Igashira , Makoto Kinoshita , Kenichi Yamamoto , Kyuto Sonehara , Mayu Yagita , Akiko Hosokawa , Daisuke Motooka , Yuki Matsumoto , Hidetoshi Matsuoka , Maiko Yoshimura , Shiro Ohshima , Shota Nakamura , Hidenori Inohara , Hideki Mochizuki , Kiyoshi Takeda , Atsushi Kumanogoh , Yukinori Okada

ETS1 governs pathological tissue-remodeling programs in disease-associated fibroblasts.

Nature immunology

Avec: Minglu Yan , Noriko Komatsu , Ryunosuke Muro , Nam Cong-Nhat Huynh , Yoshihiko Tomofuji , Yukinori Okada , Hiroshi I Suzuki , Hiroyuki Takaba , Riko Kitazawa , Sohei Kitazawa , Warunee Pluemsakunthai , Yuichi Mitsui , Takashi Satoh , Tadashi Okamura , Takeshi Nitta , Sin-Hyeog Im , Chan Johng Kim , George Kollias , Sakae Tanaka , Kazuo Okamoto , Masayuki Tsukasaki , Hiroshi Takayanagi

Fibroblasts as a source of self-antigens for central immune tolerance.

Nature immunology

Avec: Takeshi Nitta , Masanori Tsutsumi , Sachiko Nitta , Ryunosuke Muro , Emma C Suzuki , Kenta Nakano , Yoshihiko Tomofuji , Shinichiro Sawa , Tadashi Okamura , Josef M Penninger , Hiroshi Takayanagi

SLE stratification based on BAFF and IFN-I bioactivity for biologics and implications of BAFF produced by glomeruli in lupus nephritis.

Rheumatology (Oxford, England)

Avec: Eri Itotagawa , Yoshihiko Tomofuji , Yasuhiro Kato , Hachiro Konaka , Kohei Tsujimoto , JeongHoon Park , Daiki Nagira , Takehiro Hirayama , Tatsunori Jo , Toru Hirano , Takayoshi Morita , Masayuki Nishide , Sumiyuki Nishida , Yoshihito Shima , Masashi Narazaki , Yukinori Okada , Hyota Takamatsu , Atsushi Kumanogoh

Identification of serum metabolome signatures associated with retinal and renal complications of type 2 diabetes.

Communications medicine

Avec: Yoshihiko Tomofuji , Ken Suzuki , Toshihiro Kishikawa , Nobuhiro Shojima , Jun Hosoe , Kyoko Inagaki , Sunao Matsubayashi , Hisamitsu Ishihara , Hirotaka Watada , Yasushi Ishigaki , Auteur inconnu , Hidenori Inohara , Yoshinori Murakami , Koichi Matsuda , Yukinori Okada , Toshimasa Yamauchi , Takashi Kadowaki

Single-cell analyses and host genetics highlight the role of innate immune cells in COVID-19 severity.

Nature genetics

Avec: Ryuya Edahiro , Yuya Shirai , Yusuke Takeshima , Shuhei Sakakibara , Yuta Yamaguchi , Teruaki Murakami , Takayoshi Morita , Yasuhiro Kato , Yu-Chen Liu , Daisuke Motooka , Yoko Naito , Ayako Takuwa , Fuminori Sugihara , Kentaro Tanaka , James B Wing , Kyuto Sonehara , Yoshihiko Tomofuji , Auteur inconnu , Ho Namkoong , Hiromu Tanaka , Ho Lee , Koichi Fukunaga , Haruhiko Hirata , Yoshito Takeda , Daisuke Okuzaki , Atsushi Kumanogoh , Yukinori Okada

OMARU: a robust and multifaceted pipeline for metagenome-wide association study.

NAR genomics and bioinformatics

Avec: Toshihiro Kishikawa , Yoshihiko Tomofuji , Hidenori Inohara , Yukinori Okada

Quantification of escape from X chromosome inactivation with single-cell omics data reveals heterogeneity across cell types and tissues.

Cell genomics

Avec: Yoshihiko Tomofuji , Ryuya Edahiro , Kyuto Sonehara , Yuya Shirai , Kian Hong Kock , Qingbo S Wang , Shinichi Namba , Jonathan Moody , Yoshinari Ando , Akari Suzuki , Tomohiro Yata , Kotaro Ogawa , Tatsuhiko Naito , Ho Namkoong , Quy Xiao Xuan Lin , Eliora Violain Buyamin , Le Min Tan , Radhika Sonthalia , Kyung Yeon Han , Hiromu Tanaka , Ho Lee , Auteur inconnu , Tatsusada Okuno , Boxiang Liu , Koichi Matsuda , Koichi Fukunaga , Hideki Mochizuki , Woong-Yang Park , Kazuhiko Yamamoto , Chung-Chau Hon , Jay W Shin , Shyam Prabhakar , Atsushi Kumanogoh , Yukinori Okada

A case of complete atrioventricular block in secondary hemophagocytic syndrome/hemophagocytic lymphohistiocytosis recovered by plasma exchange and cytokine absorbing therapy with AN69ST continuous hemodiafiltration.

Immunological medicine

Avec: Yoshihiro Harano , Yuichi Ishikawa , Koto Hattori , Mami Ichinose , Yoshihiko Tomofuji , Hiroshi Okano , Gen Owada , Yasuhiro Kimura , Taikan Nanao , Junichi Fujimoto , Hideo Nishizawa , Yuto Iioka , Jun Osada , Michio Fujiwara , Yasuhiko Kita

Successful treatment of refractory acute lupus haemophagocytic syndrome using rituximab: a case report.

Modern rheumatology case reports

Avec: Yoshihiko Tomofuji , Yuichi Ishikawa , Koto Hattori , Michio Fujiwara , Yasuhiko Kita

Analysis of gut microbiome, host genetics, and plasma metabolites reveals gut microbiome-host interactions in the Japanese population.

Cell reports

Avec: Yoshihiko Tomofuji , Toshihiro Kishikawa , Kyuto Sonehara , Yuichi Maeda , Kotaro Ogawa , Shuhei Kawabata , Eri Oguro-Igashira , Tatsusada Okuno , Takuro Nii , Makoto Kinoshita , Masatoshi Takagaki , Kenichi Yamamoto , Noriko Arase , Mayu Yagita-Sakamaki , Akiko Hosokawa , Daisuke Motooka , Yuki Matsumoto , Hidetoshi Matsuoka , Maiko Yoshimura , Shiro Ohshima , Shota Nakamura , Manabu Fujimoto , Hidenori Inohara , Haruhiko Kishima , Hideki Mochizuki , Kiyoshi Takeda , Atsushi Kumanogoh , Yukinori Okada

Reconstruction of the personal information from human genome reads in gut metagenome sequencing data.

Nature microbiology

Avec: Yoshihiko Tomofuji , Kyuto Sonehara , Toshihiro Kishikawa , Yuichi Maeda , Kotaro Ogawa , Shuhei Kawabata , Takuro Nii , Tatsusada Okuno , Eri Oguro-Igashira , Makoto Kinoshita , Masatoshi Takagaki , Kenichi Yamamoto , Takashi Kurakawa , Mayu Yagita-Sakamaki , Akiko Hosokawa , Daisuke Motooka , Yuki Matsumoto , Hidetoshi Matsuoka , Maiko Yoshimura , Shiro Ohshima , Shota Nakamura , Hidenori Inohara , Haruhiko Kishima , Hideki Mochizuki , Kiyoshi Takeda , Atsushi Kumanogoh , Yukinori Okada

Prokaryotic and viral genomes recovered from 787 Japanese gut metagenomes revealed microbial features linked to diets, populations, and diseases.

Cell genomics

Avec: Yoshihiko Tomofuji , Toshihiro Kishikawa , Yuichi Maeda , Kotaro Ogawa , Yuriko Otake-Kasamoto , Shuhei Kawabata , Takuro Nii , Tatsusada Okuno , Eri Oguro-Igashira , Makoto Kinoshita , Masatoshi Takagaki , Naoki Oyama , Kenichi Todo , Kenichi Yamamoto , Kyuto Sonehara , Mayu Yagita , Akiko Hosokawa , Daisuke Motooka , Yuki Matsumoto , Hidetoshi Matsuoka , Maiko Yoshimura , Shiro Ohshima , Shinichiro Shinzaki , Shota Nakamura , Hideki Iijima , Hidenori Inohara , Haruhiko Kishima , Tetsuo Takehara , Hideki Mochizuki , Kiyoshi Takeda , Atsushi Kumanogoh , Yukinori Okada

Metagenome-wide association study revealed disease-specific landscape of the gut microbiome of systemic lupus erythematosus in Japanese.

Annals of the rheumatic diseases

Avec: Yoshihiko Tomofuji , Yuichi Maeda , Eri Oguro-Igashira , Toshihiro Kishikawa , Kenichi Yamamoto , Kyuto Sonehara , Daisuke Motooka , Yuki Matsumoto , Hidetoshi Matsuoka , Maiko Yoshimura , Mayu Yagita , Takuro Nii , Shiro Ohshima , Shota Nakamura , Hidenori Inohara , Kiyoshi Takeda , Atsushi Kumanogoh , Yukinori Okada

Kinetics of denaturation and renaturation processes of double-stranded helical polysaccharide, xanthan in aqueous sodium chloride.

Carbohydrate polymers

Avec: Yu Tomofuji , Koichi Matsuo , Ken Terao

Réseau de co-auteurs

Yukinori Okada 11 collaborations

Atsushi Kumanogoh 8 collaborations

Toshihiro Kishikawa 7 collaborations

Kyuto Sonehara 7 collaborations

Hidenori Inohara 7 collaborations

Daisuke Motooka 6 collaborations

Yuichi Maeda 5 collaborations

Kotaro Ogawa 5 collaborations

Takuro Nii 5 collaborations

Tatsusada Okuno 5 collaborations

Eri Oguro-Igashira 5 collaborations

Kenichi Yamamoto 5 collaborations

Yuki Matsumoto 5 collaborations

Hidetoshi Matsuoka 5 collaborations

Maiko Yoshimura 5 collaborations

Shiro Ohshima 5 collaborations

Shota Nakamura 5 collaborations

Hideki Mochizuki 5 collaborations

Kiyoshi Takeda 5 collaborations

Makoto Kinoshita 4 collaborations

Akiko Hosokawa 4 collaborations

Tadashi Okamura 3 collaborations

Hiroshi Takayanagi 3 collaborations

Mayu Yagita 3 collaborations

None None 3 collaborations

Shuhei Kawabata 3 collaborations

Masatoshi Takagaki 3 collaborations

Haruhiko Kishima 3 collaborations

Hiroyuki Takaba 2 collaborations

Hiroshi I Suzuki 2 collaborations

Ryunosuke Muro 2 collaborations

Takeshi Nitta 2 collaborations

Yasuhiro Kato 2 collaborations

Takayoshi Morita 2 collaborations

Koichi Matsuda 2 collaborations

Ryuya Edahiro 2 collaborations

Yuya Shirai 2 collaborations

Ho Namkoong 2 collaborations

Hiromu Tanaka 2 collaborations

Ho Lee 2 collaborations

Koichi Fukunaga 2 collaborations

Yuichi Ishikawa 2 collaborations

Koto Hattori 2 collaborations

Michio Fujiwara 2 collaborations

Yasuhiko Kita 2 collaborations

Mayu Yagita-Sakamaki 2 collaborations

Rayene Benlaribi 1 collaboration

Cristian David Peña Martinez 1 collaboration

Yoshihiro Abe 1 collaboration

Yasuyuki Morishita 1 collaboration

Akashi Taguchi 1 collaboration

Tatsuhiko Kodama 1 collaboration

Minglu Yan 1 collaboration

Noriko Komatsu 1 collaboration

Nam Cong-Nhat Huynh 1 collaboration

Riko Kitazawa 1 collaboration

Sohei Kitazawa 1 collaboration

Warunee Pluemsakunthai 1 collaboration

Yuichi Mitsui 1 collaboration

Takashi Satoh 1 collaboration

Sin-Hyeog Im 1 collaboration

Chan Johng Kim 1 collaboration

George Kollias 1 collaboration

Sakae Tanaka 1 collaboration

Kazuo Okamoto 1 collaboration

Masayuki Tsukasaki 1 collaboration

Masanori Tsutsumi 1 collaboration

Sachiko Nitta 1 collaboration

Emma C Suzuki 1 collaboration

Kenta Nakano 1 collaboration

Shinichiro Sawa 1 collaboration

Josef M Penninger 1 collaboration

Eri Itotagawa 1 collaboration

Hachiro Konaka 1 collaboration

Kohei Tsujimoto 1 collaboration

JeongHoon Park 1 collaboration

Daiki Nagira 1 collaboration

Takehiro Hirayama 1 collaboration

Tatsunori Jo 1 collaboration

Toru Hirano 1 collaboration

Masayuki Nishide 1 collaboration

Sumiyuki Nishida 1 collaboration

Yoshihito Shima 1 collaboration

Masashi Narazaki 1 collaboration

Hyota Takamatsu 1 collaboration

Ken Suzuki 1 collaboration

Nobuhiro Shojima 1 collaboration

Jun Hosoe 1 collaboration

Kyoko Inagaki 1 collaboration

Sunao Matsubayashi 1 collaboration

Hisamitsu Ishihara 1 collaboration

Hirotaka Watada 1 collaboration

Yasushi Ishigaki 1 collaboration

Yoshinori Murakami 1 collaboration

Toshimasa Yamauchi 1 collaboration

Takashi Kadowaki 1 collaboration

Yusuke Takeshima 1 collaboration

Shuhei Sakakibara 1 collaboration

Yuta Yamaguchi 1 collaboration

Teruaki Murakami 1 collaboration

Yu-Chen Liu 1 collaboration

Yoko Naito 1 collaboration

Ayako Takuwa 1 collaboration

Fuminori Sugihara 1 collaboration

Kentaro Tanaka 1 collaboration

James B Wing 1 collaboration

Haruhiko Hirata 1 collaboration

Yoshito Takeda 1 collaboration

Daisuke Okuzaki 1 collaboration

Kian Hong Kock 1 collaboration

Qingbo S Wang 1 collaboration

Shinichi Namba 1 collaboration

Jonathan Moody 1 collaboration

Yoshinari Ando 1 collaboration

Akari Suzuki 1 collaboration

Tomohiro Yata 1 collaboration

Tatsuhiko Naito 1 collaboration

Quy Xiao Xuan Lin 1 collaboration

Eliora Violain Buyamin 1 collaboration

Le Min Tan 1 collaboration

Radhika Sonthalia 1 collaboration

Kyung Yeon Han 1 collaboration

Boxiang Liu 1 collaboration

Woong-Yang Park 1 collaboration

Kazuhiko Yamamoto 1 collaboration

Chung-Chau Hon 1 collaboration

Jay W Shin 1 collaboration

Shyam Prabhakar 1 collaboration

Yoshihiro Harano 1 collaboration

Mami Ichinose 1 collaboration

Hiroshi Okano 1 collaboration

Gen Owada 1 collaboration

Yasuhiro Kimura 1 collaboration

Taikan Nanao 1 collaboration

Junichi Fujimoto 1 collaboration

Hideo Nishizawa 1 collaboration

Yuto Iioka 1 collaboration

Jun Osada 1 collaboration

Noriko Arase 1 collaboration

Manabu Fujimoto 1 collaboration

Takashi Kurakawa 1 collaboration

Yuriko Otake-Kasamoto 1 collaboration

Naoki Oyama 1 collaboration

Kenichi Todo 1 collaboration

Shinichiro Shinzaki 1 collaboration

Hideki Iijima 1 collaboration

Tetsuo Takehara 1 collaboration

Yu Tomofuji 1 collaboration

Koichi Matsuo 1 collaboration

Ken Terao 1 collaboration