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Acides aminés, peptides et protéines
Protéines
Protéines du cytosquelette
Protéines de filaments intermédiaires
Protéines de filaments intermédiaires : Questions médicales fréquentes
Termes MeSH sélectionnés :
Apc1 Subunit, Anaphase-Promoting Complex-Cyclosome
Général
1
Intermediate Filament Proteins
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Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 28/02/2025
Contenu vérifié selon les dernières recommandations médicales
9 publications dans cette catégorie
Affiliations :
Institute for X-Ray Physics, University of Goettingen, Friedrich-Hund-Platz 1, 37077 Göttingen, Germany.
8 publications dans cette catégorie
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Cell Polarity, Migration and Cancer Unit, Institut Pasteur, UMR3691 CNRS, Équipe Labellisée Ligue Contre le Cancer, F-75015 Paris, France. Electronic address: setienne@pasteur.fr.
6 publications dans cette catégorie
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Institute for X-Ray Physics, University of Göttingen, Friedrich-Hund-Platz 1, 37077 Göttingen, Germany.
5 publications dans cette catégorie
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Institute for X-Ray Physics, University of Göttingen, Friedrich-Hund-Platz 1, 37077 Göttingen, Germany.
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4 publications dans cette catégorie
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Institute of Molecular and Cellular Anatomy, RWTH Aachen University, Aachen, Germany.
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Max Delbrück Center for Molecular Medicine, Robert-Rössle-Straße 10, D-13125 Berlin, Germany.
German Centre for Cardiovascular Research (DZHK), Partner Site Berlin, D-10785 Berlin, Germany.
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3 publications dans cette catégorie
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Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, MI 48109, USA; Department of Dermatology, University of Michigan, Ann Arbor, MI 48109, USA; Rogel Cancer Center, University of Michigan, Ann Arbor, MI 48109, USA. Electronic address: coulombe@umich.edu.
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Department of Mathematics, University of Manitoba, Winnipeg, MB, Canada.
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Department of Biochemistry, University of Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland.
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Institute of Neuropathology, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nürnberg, Erlangen, Germany.
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Ken and Ruth Davee Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
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3 publications dans cette catégorie
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Institute for Dynamics of Complex Systems, University of Göttingen, Friedrich-Hund-Platz 1, 37077 Göttingen, Germany.
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2 publications dans cette catégorie
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Institute of Protein Research, Russian Academy of Sciences, Moscow, 119334, Russia.
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Institute of Protein Research, Russian Academy of Sciences, Moscow, 119334, Russia. alexminin@gmail.com.
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Department of Histology and Embryology, Faculty of Veterinary Medicine, Dicle University, Diyarbakır, Turkey.
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Department of Mathematics, Brigham Young University, 344 TMCB, Provo, Utah 84602-6539, USA. Electronic address: dallon@math.byu.edu.
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2 publications dans cette catégorie
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Institut Pasteur Paris CNRS UMR3691, Cell Polarity, Migration and Cancer Unit, Equipe Labellisée Ligue Contre le Cancer, 25 rue du Dr Roux, Paris Cedex 15, 75724, France.
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Turku Bioscience Centre, University of Turku and Åbo Akademi University, 20520 Turku, Finland.
Faculty of Science and Engineering, Cell Biology, Åbo Akademi University, 20520 Turku, Finland.
Euro-Bioimaging ERIC, 20520 Turku, Finland.
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Celica BIOMEDICAL, 1000 Ljubljana, Slovenia.
Department of Biochemistry and Cell Biology, Max F. Perutz Laboratories, University of Vienna, 1030 Vienna, Austria.
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Genome-wide association studies (GWAS) are one of the most common approaches to identify genetic loci that are associated with bone mineral density (BMD). Such novel genetic loci represent new potenti...
The anaphase-promoting complex/cyclosome (APC/C) is a complicated cellular component that plays significant roles in regulating the cell cycle process of eukaryotic organisms. The spatiotemporal regul...
Among various post-translational modifications of histones, ubiquitylation plays a crucial role in transcription regulation. Histone mono-ubiquitylation by RING finger motif-containing ubiquitin ligas...
The anaphase-promoting complex/cyclosome (APC/C) coordinates advancement through mitosis via temporally controlled polyubiquitination events. Despite the long-appreciated spatial organization of key e...
The anaphase promoting complex/cyclosome (APC/C) is a large multi-subunit complex, regulating plant development and cell cycle. In plants, the APC/C gene family has been identified in Arabidopsis, ric...
Improving the chemotherapy sensitivity of bladder cancer is a current clinical challenge. It is critical to seek out effective combination therapies that include low doses of cisplatin due to its dose...
DNA double-strand breaks (DSBs) contribute to genome instability, a key feature of cancer. DSBs are mainly repaired by homologous recombination (HR) and non-homologous end-joining (NHEJ). We investiga...
Deciphering the protein posttranslational modification (PTM) code is one of the greatest biochemical challenges of our time. Phosphorylation and ubiquitylation are key PTMs that dictate protein functi...
Substrate polyubiquitination drives a myriad of cellular processes, including the cell cycle, apoptosis and immune responses. Polyubiquitination is highly dynamic, and obtaining mechanistic insight ha...
Paclitaxel induces multipolar spindles at clinically relevant doses but does not substantially increase mitotic indices. Paclitaxel's anti-cancer effects are hypothesized to occur by promoting chromos...