Titre : Protéines de filaments intermédiaires

Protéines de filaments intermédiaires : Questions médicales fréquentes

Termes MeSH sélectionnés :

Drug Development

Questions fréquentes et termes MeSH associés

Général 1

#1

Erreur lors de la génération.

Veuillez réessayer ultérieurement.
Intermediate Filament Proteins
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Dr Olivier Menir

Contenu validé par Dr Olivier Menir

Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale


Validation scientifique effectuée le 28/02/2025

Contenu vérifié selon les dernières recommandations médicales

Auteurs principaux

Sarah Köster

9 publications dans cette catégorie

Affiliations :
  • Institute for X-Ray Physics, University of Goettingen, Friedrich-Hund-Platz 1, 37077 Göttingen, Germany.

Sandrine Etienne-Manneville

8 publications dans cette catégorie

Affiliations :
  • Cell Polarity, Migration and Cancer Unit, Institut Pasteur, UMR3691 CNRS, Équipe Labellisée Ligue Contre le Cancer, F-75015 Paris, France. Electronic address: setienne@pasteur.fr.

Charlotta Lorenz

6 publications dans cette catégorie

Affiliations :
  • Institute for X-Ray Physics, University of Göttingen, Friedrich-Hund-Platz 1, 37077 Göttingen, Germany.

Anna V Schepers

5 publications dans cette catégorie

Affiliations :
  • Institute for X-Ray Physics, University of Göttingen, Friedrich-Hund-Platz 1, 37077 Göttingen, Germany.

Rudolf E Leube

4 publications dans cette catégorie

Affiliations :
  • Institute of Molecular and Cellular Anatomy, RWTH Aachen University, Aachen, Germany.

Julia Kraxner

4 publications dans cette catégorie

Affiliations :
  • Max Delbrück Center for Molecular Medicine, Robert-Rössle-Straße 10, D-13125 Berlin, Germany.
  • German Centre for Cardiovascular Research (DZHK), Partner Site Berlin, D-10785 Berlin, Germany.
Publications dans "Protéines de filaments intermédiaires" :

Pierre A Coulombe

3 publications dans cette catégorie

Affiliations :
  • Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, MI 48109, USA; Department of Dermatology, University of Michigan, Ann Arbor, MI 48109, USA; Rogel Cancer Center, University of Michigan, Ann Arbor, MI 48109, USA. Electronic address: coulombe@umich.edu.
Publications dans "Protéines de filaments intermédiaires" :

Stéphanie Portet

3 publications dans cette catégorie

Affiliations :
  • Department of Mathematics, University of Manitoba, Winnipeg, MB, Canada.

Ohad Medalia

3 publications dans cette catégorie

Affiliations :
  • Department of Biochemistry, University of Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland.
Publications dans "Protéines de filaments intermédiaires" :

Harald Herrmann

3 publications dans cette catégorie

Affiliations :
  • Institute of Neuropathology, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nürnberg, Erlangen, Germany.

Puneet Opal

3 publications dans cette catégorie

Affiliations :
  • Ken and Ruth Davee Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
Publications dans "Protéines de filaments intermédiaires" :

Stefan Klumpp

3 publications dans cette catégorie

Affiliations :
  • Institute for Dynamics of Complex Systems, University of Göttingen, Friedrich-Hund-Platz 1, 37077 Göttingen, Germany.
Publications dans "Protéines de filaments intermédiaires" :

Alexander A Dayal

2 publications dans cette catégorie

Affiliations :
  • Institute of Protein Research, Russian Academy of Sciences, Moscow, 119334, Russia.

Alexander A Minin

2 publications dans cette catégorie

Affiliations :
  • Institute of Protein Research, Russian Academy of Sciences, Moscow, 119334, Russia. alexminin@gmail.com.

Hakan Sağsöz

2 publications dans cette catégorie

Affiliations :
  • Department of Histology and Embryology, Faculty of Veterinary Medicine, Dicle University, Diyarbakır, Turkey.
Publications dans "Protéines de filaments intermédiaires" :

J C Dallon

2 publications dans cette catégorie

Affiliations :
  • Department of Mathematics, Brigham Young University, 344 TMCB, Provo, Utah 84602-6539, USA. Electronic address: dallon@math.byu.edu.
Publications dans "Protéines de filaments intermédiaires" :

Cécile Leduc

2 publications dans cette catégorie

Affiliations :
  • Institut Pasteur Paris CNRS UMR3691, Cell Polarity, Migration and Cancer Unit, Equipe Labellisée Ligue Contre le Cancer, 25 rue du Dr Roux, Paris Cedex 15, 75724, France.
Publications dans "Protéines de filaments intermédiaires" :

John E Eriksson

2 publications dans cette catégorie

Affiliations :
  • Turku Bioscience Centre, University of Turku and Åbo Akademi University, 20520 Turku, Finland.
  • Faculty of Science and Engineering, Cell Biology, Åbo Akademi University, 20520 Turku, Finland.
  • Euro-Bioimaging ERIC, 20520 Turku, Finland.
Publications dans "Protéines de filaments intermédiaires" :

Gerhard Wiche

2 publications dans cette catégorie

Affiliations :
  • Celica BIOMEDICAL, 1000 Ljubljana, Slovenia.
  • Department of Biochemistry and Cell Biology, Max F. Perutz Laboratories, University of Vienna, 1030 Vienna, Austria.
Publications dans "Protéines de filaments intermédiaires" :

Mark Kittisopikul

2 publications dans cette catégorie

Affiliations :
  • Department of Cell and Developmental Biology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
Publications dans "Protéines de filaments intermédiaires" :

Sources (10000 au total)

Costs of Drug Development and Research and Development Intensity in the US, 2000-2018.

Understanding the cost of drug development can help inform the development of policies to reduce costs, encourage innovation, and improve patient access to drugs.... To estimate the cost of drug development by therapeutic class and trends in pharmaceutical research and development (R&D) intensity over time.... In this economic evaluation study, an analytical model of drug development constructed using public and proprietary sources that collectively cover data from 2000 to 2018 was used to estimate the cost... Three measures of development cost from nonclinical through postmarketing stages were estimated: mean out-of-pocket cost or cash outlay, mean expected cost, and mean expected capitalized cost. Pharmac... The estimated mean cost of developing a new drug was approximately $172.7 million (2018 dollars) (range, $72.5 million for genitourinary to $297.2 million for pain and anesthesia), inclusive of postma... In this economic evaluation of new drug development costs, even though the cost of drug development appears to have remained stable, R&D intensity of large pharmaceutical companies remained relatively...