Cell Polarity, Migration and Cancer Unit, Institut Pasteur, UMR3691 CNRS, Équipe Labellisée Ligue Contre le Cancer, F-75015 Paris, France. Electronic address: setienne@pasteur.fr.
Publications dans "Protéines de filaments intermédiaires" :
Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, MI 48109, USA; Department of Dermatology, University of Michigan, Ann Arbor, MI 48109, USA; Rogel Cancer Center, University of Michigan, Ann Arbor, MI 48109, USA. Electronic address: coulombe@umich.edu.
Publications dans "Protéines de filaments intermédiaires" :
Institut Pasteur Paris CNRS UMR3691, Cell Polarity, Migration and Cancer Unit, Equipe Labellisée Ligue Contre le Cancer, 25 rue du Dr Roux, Paris Cedex 15, 75724, France.
Publications dans "Protéines de filaments intermédiaires" :
A statistical analysis of maximum temperature from twelve weather stations in parts of Guinea is provided. Using maximum likelihood estimation, maximum temperature data was fitted by the Generalized E...
Vignette methods are widely used in psychology and the social sciences to obtain responses to multi-dimensional scenarios or situations. Where quantitative data are collected this presents challenges ...
Statistical shape models (SSMs) are a popular tool to conduct morphological analysis of anatomical structures which is a crucial step in clinical practices. However, shape representations through SSMs...
The proposed anatomically parameterized SSM (ANAT[Formula: see text]) is based on learning a linear mapping between shape coefficients (latent space) and selected anatomical parameters (anatomical spa...
Anatomical measures of the synthetically generated shapes exhibited realistic statistics. The learned matrices corroborated well with the obtained statistical relationship, while the two SSMs achieved...
This study demonstrates the use of anatomical representation for creating anatomically parameterized SSMs and as a result, removes the limited clinical interpretability of standard SSMs....
The proposed models could help analyze differences in relevant bone morphometry between populations, and be integrated in patient-specific pre-surgery planning or in-surgery assessment....
Congenital heart disease (CHD) is a collection of anatomically and clinically heterogeneous structure anomalies of heart at birth. Finding genetic causes of CHD can not only shed light on developmenta...
A recent surge of patent applications among public hospitals in China has aroused significant research interest. A country's healthcare innovation capacity can be measured by its number of patents. Th...
For the representative problem of prostate cancer grading, we sought to simultaneously model both the continuous nature of the case spectrum and the decision thresholds of individual pathologists, all...
Experts and pathology residents each rated a standardized set of prostate cancer histopathological images on the International Society of Urological Pathologists (ISUP) scale used in clinical practice...
The slides were rated by 36 physicians in total: 23 ISUP pathologists and 13 residents. As anticipated, the cases showed a full continuous range of diagnostic severity. Cases ranged along a logit scal...
We present a method that allows simultaneous quantification of both the confusability of a particular case and the skill with which raters can distinguish the cases....
The technique generalizes beyond the current example to other clinical situations in which a diagnostician must impose an ordinal rating on a biological spectrum....
In health research, several chronic diseases are susceptible to competing risks (CRs). Initially, statistical models (SM) were developed to estimate the cumulative incidence of an event in the presenc...
A dataset with 3826 retrospectively collected patients with extremity soft-tissue sarcoma (eSTS) and nine predictors is used to evaluate model-predictive performance in terms of discrimination and cal...
Based on the original eSTS data, 100 bootstrapped training datasets are drawn. Performance of the final models is assessed on validation data (left out samples) by employing as measures the Brier scor...
Overall, ML techniques are less practical as they require substantial implementation time (data preprocessing, hyperparameter tuning, computational intensity), whereas regression methods can perform w...
The brain is a highly complex system. Most of such complexity stems from the intermingled connections between its parts, which give rise to rich dynamics and to the emergence of high-level cognitive f...
Diabetic neuropathy is a disorder characterized by impaired nerve function and reduction of the number of epidermal nerve fibers per epidermal surface. Additionally, as neuropathy related nerve fiber ...
