Comment diagnostiquer une hyperuricémie ?

Un test sanguin mesure le taux d'acide urique pour diagnostiquer l'hyperuricémie.

Quels tests pour la goutte ?

L'analyse du liquide synovial et des tests sanguins pour l'acide urique sont utilisés.

Quels symptômes indiquent une crise de goutte ?

Douleur intense, rougeur et gonflement d'une articulation, souvent le gros orteil.

Comment évaluer une maladie liée aux purines ?

Des tests génétiques et des analyses biochimiques peuvent être nécessaires.

Quel rôle des purines dans le diagnostic ?

Les niveaux de purines peuvent indiquer des troubles métaboliques ou des maladies rénales.

Quels sont les symptômes de l'hyperuricémie ?

Souvent asymptomatique, mais peut causer des douleurs articulaires et des calculs rénaux.

Quels signes de goutte aiguë ?

Douleur intense, rougeur, chaleur et gonflement d'une articulation, souvent nocturne.

Comment se manifeste une crise de goutte ?

Une douleur soudaine et sévère dans une articulation, souvent accompagnée d'inflammation.

Quels symptômes des troubles des purines ?

Fatigue, douleurs articulaires, et parfois des problèmes rénaux ou hépatiques.

Quels symptômes d'une maladie de Wilson ?

Accumulation de cuivre, troubles neurologiques, et symptômes hépatiques.

Comment prévenir l'hyperuricémie ?

Adopter un régime pauvre en purines et éviter l'alcool et les boissons sucrées.

Quelles habitudes pour éviter la goutte ?

Maintenir un poids santé, rester hydraté et limiter les aliments riches en purines.

Comment réduire le risque de calculs rénaux ?

Boire beaucoup d'eau et éviter les aliments riches en oxalates et purines.

Quels conseils diététiques pour les purines ?

Limiter les viandes rouges, les fruits de mer et les boissons alcoolisées.

Comment surveiller les niveaux d'acide urique ?

Des tests sanguins réguliers pour surveiller les niveaux d'acide urique et ajuster le régime.

Comment traiter l'hyperuricémie ?

Des médicaments comme les inhibiteurs de la xanthine oxydase et des changements alimentaires.

Quel traitement pour la goutte ?

Anti-inflammatoires non stéroïdiens (AINS) et colchicine pour soulager la douleur.

Comment prévenir les crises de goutte ?

Éviter les aliments riches en purines et maintenir une hydratation adéquate.

Quels médicaments pour les troubles des purines ?

Des médicaments spécifiques selon le trouble, comme les uricosuriques pour l'hyperuricémie.

Comment gérer les calculs rénaux liés aux purines ?

Hydratation, modifications alimentaires et parfois intervention chirurgicale.

Quelles complications de la goutte ?

Arthrite chronique, dépôts de tophus et risque accru de maladies cardiovasculaires.

Quels risques liés à l'hyperuricémie ?

Peut entraîner des calculs rénaux, des maladies rénales et des problèmes cardiovasculaires.

Comment l'hyperuricémie affecte-t-elle les reins ?

Peut provoquer une néphropathie urique, entraînant des lésions rénales.

Quelles complications des troubles des purines ?

Peuvent inclure des problèmes hépatiques, neurologiques et des troubles métaboliques.

Quels effets à long terme de la goutte ?

Peut entraîner des dommages articulaires permanents et des complications systémiques.

Quels facteurs de risque pour l'hyperuricémie ?

Obésité, consommation excessive d'alcool, régime riche en purines et antécédents familiaux.

Qui est à risque de goutte ?

Les hommes, les personnes obèses et celles ayant des antécédents familiaux de goutte.

Quels médicaments augmentent le risque d'hyperuricémie ?

Diurétiques, aspirine à faible dose et certains médicaments immunosuppresseurs.

Quel rôle de l'alimentation dans les purines ?

Une alimentation riche en viandes rouges, fruits de mer et boissons sucrées augmente le risque.

Comment l'âge influence-t-il l'hyperuricémie ?

Le risque d'hyperuricémie augmente avec l'âge, surtout chez les hommes après 40 ans.

Purines - Informations médicales vérifiées

Improving adult pulsatile minimal invasive extracorporeal circulation in a mock circulation.

May 2023

DOI: 10.1111/aor.14439 PMID: 36310392

Pulsatile extracorporeal circulation (ECC) may improve perfusion of critical organs during cardiac surgery. This study analyzed the influence of the components of a minimal invasive ECC (MiECC) on the... An aortic model with human-like geometry and compliance was perfused by a diagonal pump. Surplus hemodynamic energy (SHE) was determined from flow and pressure data. Five adult-size oxygenator models ... Oxygenator models showed up to twofold differences in pressure gradients and influenced SHE at flow rates up to 2.0 L min... Proper selection of components and optimizations of pump settings significantly improved pulse pressure and SHE of pulsatile MiECC. Surplus hemodynamic energy depended on flow rate with a maximum at 1...

Adult Humans Extracorporeal Membrane Oxygenation Models, Cardiovascular Extracorporeal Circulation +3 autres

Minimal invasive extracorporeal circulation an alternative to ECMO in ventricular tachycardia ablation.

Sep 2023

DOI: 10.1051/ject/2023031 PMID: 37682213

The advantages of mechanical assistance during ventricular tachycardia (VT) ablation have not been clinically demonstrated. We propose and discuss a technique, set up by us, that makes use of minimall... We present a retrospective case series of ten patients with valvular heart disease and unresponsive Ventricular Tachycardia (VT) who underwent VT ablation with MiECC support. The mean age of the patie... A total of 140 min, the following parameters were evaluated and recorded for 140 min. Central venous pressure (CVP) was used to evaluate excess volume. During the first 5 min, the mean was 15 mmHg, wi... In this preliminary retrospective case series, the MiECC type III system may represent the ideal support system during VT ablation, and further studies are needed to support this preliminary report....

Humans Middle Aged Aged Aged, 80 and over Extracorporeal Membrane Oxygenation +4 autres

First worldwide use of the hybrid system for extracorporeal circulation in heart transplant.

27 Aug 2024

DOI: 10.1186/s13019-024-03010-4 PMID: 39192346

This case report documents the first worldwide use of the Hybrid System from Spectrum Medical in a heart transplant procedure, focusing on its safety and efficacy. Traditional cardiopulmonary bypass s... A 41-year-old male managed with a left ventricular assist device because of dilated cardiomyopathy underwent a heart transplant using the Hybrid System. The perioperative and postoperative data provid... The Hybrid System is safe and efficient. The successful implementation in this case highlights its advantages over traditional cardiopulmonary bypass systems, suggesting a promising future in cardiac ...

Humans Male Heart Transplantation Adult Extracorporeal Circulation +2 autres

Three-Dimensional Magnetic Chip with Extracorporeal Circulation for Circulating Tumor Cell In Vivo Detection and Tumor Growth Inhibition.

06 06 2023

DOI: 10.1021/acs.analchem.3c01753 PMID: 37218037

Liquid biopsy technology involves taking samples from body fluids in a minimally invasive way and analyzing tumor markers to achieve early diagnosis and efficacy evaluation of tumors. The development ...

Humans Neoplastic Cells, Circulating Magnetic Phenomena Extracorporeal Circulation Biomarkers, Tumor

Extracorporeal therapy of sepsis by purified granulocyte concentrates: ex vivo circulation model.

Jul 2023

DOI: 10.1111/aor.14507 PMID: 36740583

Immune cell dysfunction is a central part of immune paralysis in sepsis. Granulocyte concentrate (GC) transfusions can induce tissue damage via local effects of neutrophils. The hypothesis of an extra... Purified GC were stored for up to 3 days and compared with standard GC in an immune cell perfusion therapy model. The therapy consists of a plasma separation device and an extracorporeal circuit. Plas... In pGC, the metabolic surrogate parameters of cell functionality showed comparable courses even after a storage period of 72 h. In particular, glucose and oxygen consumption were lower after extended ... The granulocytes demonstrated full functionality in the 6 h extracorporeal circuits after 3 days storage and in septic shock plasma. This is demonstrating the functionality of the system and encourage...

Humans Granulocytes Neutrophils Sepsis Shock, Septic +2 autres

Impact of minimal invasive extracorporeal circulation on systemic inflammatory response - a randomized trial.

03 Jul 2024

DOI: 10.1186/s13019-024-02903-8 PMID: 38961388

Extracorporeal circulation causes a systemic inflammatory response, that may cause postoperative haemodynamic instability and end-organ dysfunction. This study aimed to investigate the impact of minim... Patients undergoing coronary artery bypass grafting were randomized to MiECC (n = 30) and CECC (n = 30). Primary endpoint was tumor necrosis factor-α. Secondary endpoints were other biochemical marker... Patients treated with MiECC showed significantly lower levels of tumor necrosis factor-α than CECC during and early after extracorporeal circulation (median: MiECC 3.4 pg/mL; CI 2.2-4.5 vs. CECC 4.6 p... Lower levels of TNF-α after MiECC compared with CECC may reflect reduced inflammatory response, although other biochemical markers of inflammation were comparable. Our results suggest better end-organ... NCT03216720....

Humans Male Female Extracorporeal Circulation Middle Aged +6 autres

Population pharmacokinetics of three alternative prophylactic antibiotics during cardiac surgery with extracorporeal circulation.

Jun 2023

DOI: 10.5507/bp.2022.033 PMID: 35775358

The aim of this pharmacokinetic study was to describe and quantify population pharmacokinetics of three antibiotics, cefazolin, ampicillin, and ciprofloxacin, used as antibacterial prophylaxis during ... Adult patients undergoing cardiac surgery with ECC were enrolled to this prospective, pharmacokinetic study. An intravenous bolus of 2 g of ampicillin, 2 g of cefazolin or 400 mg of ciprofloxacin was ... A total of 54 patients were enrolled into the study, 20 with ampicillin, 25 cefazolin and 9 ciprofloxacin. For all antibiotics, population pharmacokinetic models have been successfully developed.... We identified estimated glomerular filtration rate (eGFR) as the main factor determining the achievement of the pharmacokinetic/pharmacodynamic (PK/PD) target in ampicillin or cefazolin and body weigh...

Adult Humans Cefazolin Prospective Studies Antibiotic Prophylaxis +5 autres

Circulating Levels of Ferritin, RDW, PTLs as Predictive Biomarkers of Postoperative Atrial Fibrillation Risk after Cardiac Surgery in Extracorporeal Circulation.

26 Nov 2022

DOI: 10.3390/ijms232314800 PMID: 36499124

Postoperative atrial fibrillation (POAF) is the most common arrhythmia after cardiac surgery in conventional extracorporeal circulation (CECC), with an incidence of 15-50%. The POAF pathophysiology is...

Male Female Humans Middle Aged Aged +8 autres

[Thrombotic occlusion of the extracorporeal circulation during hepatic chemosaturation despite targeted anticoagulation : A case report].

11 2022

DOI: 10.1007/s00101-022-01175-y PMID: 35925192

Percutaneous hepatic chemosaturation is a treatment option for unresectable primary or secondary liver tumors. In this procedure the part of the inferior vena cava (VCI) that collects blood from the h...

Humans Liver Neoplasms Melphalan Extracorporeal Circulation Anticoagulants

Extracorporeal Rewarming Is Associated With Increased Survival Rate in Severely Hypothermic Patients With Preserved Spontaneous Circulation.

01 08 2023

DOI: 10.1097/MAT.0000000000001935 PMID: 37039862

Treatment recommendations for rewarming patients in severe accidental hypothermia with preserved spontaneous circulation have a weak evidence due to the absence of randomized clinical trials. We aimed...

Adult Humans Hypothermia Rewarming Retrospective Studies +4 autres

Purines : Questions médicales fréquentes

Termes MeSH sélectionnés :

Questions fréquentes et termes MeSH associés

Diagnostic 5

Symptômes 5

Prévention 5

Traitements 5

Complications 5

Facteurs de risque 5

Contenu validé par Dr Olivier Menir

Sous-catégories

Adénine

Allopurinol

Mercaptopurine

Purinones

Roscovitine

Citrate de sildénafil

Tioguanine

Amino-2 purine

Cytokinine

Famciclovir

Ténofovir

Hypoxanthines

Xanthines

Kinétine

Zéatine

Guanine

Hypoxanthine

Caféine

Théobromine

Théophylline

Acide urique

Xanthine

Aciclovir

8-Azaguanine

Pentoxifylline

Diphylline

Xanthine(isobutyl-3 methyl-1)

Nicotinate de xanthinol

Ganciclovir

Valaciclovir

Valganciclovir

Auteurs principaux

Sources (9962 au total)