Titre : Thrombospondine-1

Thrombospondine-1 : Questions médicales fréquentes

Termes MeSH sélectionnés :

Pilot Projects
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"Diagnostic sur Thrombospondine-1", "description": "Comment diagnostiquer une anomalie de thrombospondine-1 ?\nQuels examens sont utilisés pour évaluer la thrombospondine-1 ?\nLa biopsie est-elle nécessaire pour le diagnostic ?\nQuels symptômes peuvent indiquer un problème avec la thrombospondine-1 ?\nPeut-on utiliser l'imagerie pour évaluer la thrombospondine-1 ?", "url": "https://questionsmedicales.fr/mesh/D019700?mesh_terms=Pilot+Projects&page=2#section-diagnostic" }, { "@type": "MedicalWebPage", "name": "Symptômes", "headline": "Symptômes sur Thrombospondine-1", "description": "Quels sont les symptômes d'une carence en thrombospondine-1 ?\nLa thrombospondine-1 affecte-t-elle la douleur ?\nY a-t-il des symptômes associés à un excès de thrombospondine-1 ?\nComment la thrombospondine-1 influence-t-elle l'angiogenèse ?\nLes troubles de thrombospondine-1 peuvent-ils causer des symptômes neurologiques ?", "url": "https://questionsmedicales.fr/mesh/D019700?mesh_terms=Pilot+Projects&page=2#section-symptômes" }, { "@type": "MedicalWebPage", "name": "Prévention", "headline": "Prévention sur Thrombospondine-1", "description": "Comment prévenir les troubles liés à la thrombospondine-1 ?\nLes dépistages réguliers sont-ils importants ?\nY a-t-il des vaccins pour prévenir les troubles de thrombospondine-1 ?\nL'évitement de certains aliments peut-il aider ?\nLe stress a-t-il un impact sur la thrombospondine-1 ?", "url": "https://questionsmedicales.fr/mesh/D019700?mesh_terms=Pilot+Projects&page=2#section-prévention" }, { "@type": "MedicalWebPage", "name": "Traitements", "headline": "Traitements sur Thrombospondine-1", "description": "Quels traitements existent pour les anomalies de thrombospondine-1 ?\nLa thérapie génique peut-elle aider avec la thrombospondine-1 ?\nLes médicaments anti-inflammatoires sont-ils efficaces ?\nPeut-on utiliser des suppléments pour la thrombospondine-1 ?\nLa chirurgie est-elle une option pour traiter les problèmes de thrombospondine-1 ?", "url": "https://questionsmedicales.fr/mesh/D019700?mesh_terms=Pilot+Projects&page=2#section-traitements" }, { "@type": "MedicalWebPage", "name": "Complications", "headline": "Complications sur Thrombospondine-1", "description": "Quelles complications peuvent survenir avec des niveaux anormaux de thrombospondine-1 ?\nLes complications neurologiques sont-elles possibles ?\nComment les complications affectent-elles la qualité de vie ?\nLes complications peuvent-elles être réversibles ?\nY a-t-il un risque accru de cancer avec des anomalies de thrombospondine-1 ?", "url": "https://questionsmedicales.fr/mesh/D019700?mesh_terms=Pilot+Projects&page=2#section-complications" }, { "@type": "MedicalWebPage", "name": "Facteurs de risque", "headline": "Facteurs de risque sur Thrombospondine-1", "description": "Quels sont les facteurs de risque pour les troubles de thrombospondine-1 ?\nL'âge influence-t-il les niveaux de thrombospondine-1 ?\nLe mode de vie peut-il affecter la thrombospondine-1 ?\nLes infections peuvent-elles influencer la thrombospondine-1 ?\nLe stress psychologique est-il un facteur de risque ?", "url": "https://questionsmedicales.fr/mesh/D019700?mesh_terms=Pilot+Projects&page=2#section-facteurs de risque" } ] }, { "@type": "FAQPage", "mainEntity": [ { "@type": "Question", "name": "Comment diagnostiquer une anomalie de thrombospondine-1 ?", "position": 1, "acceptedAnswer": { "@type": "Answer", "text": "Des tests sanguins mesurant les niveaux de thrombospondine-1 peuvent être effectués." } }, { "@type": "Question", "name": "Quels examens sont utilisés pour évaluer la thrombospondine-1 ?", "position": 2, "acceptedAnswer": { "@type": "Answer", "text": "L'immunohistochimie et les dosages ELISA sont couramment utilisés." } }, { "@type": "Question", "name": "La biopsie est-elle nécessaire pour le diagnostic ?", "position": 3, "acceptedAnswer": { "@type": "Answer", "text": "Une biopsie peut être nécessaire si des tumeurs sont suspectées." } }, { "@type": "Question", "name": "Quels symptômes peuvent indiquer un problème avec la thrombospondine-1 ?", "position": 4, "acceptedAnswer": { "@type": "Answer", "text": "Des symptômes comme des saignements ou des problèmes de cicatrisation peuvent survenir." } }, { "@type": "Question", "name": "Peut-on utiliser l'imagerie pour évaluer la thrombospondine-1 ?", "position": 5, "acceptedAnswer": { "@type": "Answer", "text": "L'imagerie peut aider à visualiser les effets des anomalies, mais pas directement la protéine." } }, { "@type": "Question", "name": "Quels sont les symptômes d'une carence en thrombospondine-1 ?", "position": 6, "acceptedAnswer": { "@type": "Answer", "text": "Les symptômes incluent des saignements excessifs et des problèmes de cicatrisation." } }, { "@type": "Question", "name": "La thrombospondine-1 affecte-t-elle la douleur ?", "position": 7, "acceptedAnswer": { "@type": "Answer", "text": "Elle peut influencer la douleur en modulant l'inflammation et la réparation tissulaire." } }, { "@type": "Question", "name": "Y a-t-il des symptômes associés à un excès de thrombospondine-1 ?", "position": 8, "acceptedAnswer": { "@type": "Answer", "text": "Un excès peut être lié à des maladies cardiovasculaires et des troubles inflammatoires." } }, { "@type": "Question", "name": "Comment la thrombospondine-1 influence-t-elle l'angiogenèse ?", "position": 9, "acceptedAnswer": { "@type": "Answer", "text": "Elle inhibe l'angiogenèse, ce qui peut entraîner des problèmes de vascularisation." } }, { "@type": "Question", "name": "Les troubles de thrombospondine-1 peuvent-ils causer des symptômes neurologiques ?", "position": 10, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des anomalies peuvent affecter la circulation sanguine cérébrale et provoquer des symptômes." } }, { "@type": "Question", "name": "Comment prévenir les troubles liés à la thrombospondine-1 ?", "position": 11, "acceptedAnswer": { "@type": "Answer", "text": "Un mode de vie sain, incluant une alimentation équilibrée et de l'exercice, est recommandé." } }, { "@type": "Question", "name": "Les dépistages réguliers sont-ils importants ?", "position": 12, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des dépistages peuvent aider à détecter précocement des anomalies liées à la thrombospondine-1." } }, { "@type": "Question", "name": "Y a-t-il des vaccins pour prévenir les troubles de thrombospondine-1 ?", "position": 13, "acceptedAnswer": { "@type": "Answer", "text": "Actuellement, il n'existe pas de vaccins spécifiques pour ces troubles." } }, { "@type": "Question", "name": "L'évitement de certains aliments peut-il aider ?", "position": 14, "acceptedAnswer": { "@type": "Answer", "text": "Éviter les aliments pro-inflammatoires peut contribuer à la gestion des symptômes." } }, { "@type": "Question", "name": "Le stress a-t-il un impact sur la thrombospondine-1 ?", "position": 15, "acceptedAnswer": { "@type": "Answer", "text": "Oui, le stress peut exacerber les symptômes et affecter la régulation de la thrombospondine-1." } }, { "@type": "Question", "name": "Quels traitements existent pour les anomalies de thrombospondine-1 ?", "position": 16, "acceptedAnswer": { "@type": "Answer", "text": "Les traitements incluent des thérapies ciblées et des transfusions sanguines si nécessaire." } }, { "@type": "Question", "name": "La thérapie génique peut-elle aider avec la thrombospondine-1 ?", "position": 17, "acceptedAnswer": { "@type": "Answer", "text": "La thérapie génique est une option prometteuse pour corriger des anomalies génétiques." } }, { "@type": "Question", "name": "Les médicaments anti-inflammatoires sont-ils efficaces ?", "position": 18, "acceptedAnswer": { "@type": "Answer", "text": "Oui, ils peuvent aider à réduire l'inflammation associée aux troubles de thrombospondine-1." } }, { "@type": "Question", "name": "Peut-on utiliser des suppléments pour la thrombospondine-1 ?", "position": 19, "acceptedAnswer": { "@type": "Answer", "text": "Des suppléments peuvent être envisagés, mais leur efficacité n'est pas bien établie." } }, { "@type": "Question", "name": "La chirurgie est-elle une option pour traiter les problèmes de thrombospondine-1 ?", "position": 20, "acceptedAnswer": { "@type": "Answer", "text": "La chirurgie peut être nécessaire pour retirer des tumeurs ou traiter des complications." } }, { "@type": "Question", "name": "Quelles complications peuvent survenir avec des niveaux anormaux de thrombospondine-1 ?", "position": 21, "acceptedAnswer": { "@type": "Answer", "text": "Des complications incluent des troubles de la coagulation et des maladies cardiovasculaires." } }, { "@type": "Question", "name": "Les complications neurologiques sont-elles possibles ?", "position": 22, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des niveaux anormaux peuvent affecter la circulation cérébrale et causer des troubles neurologiques." } }, { "@type": "Question", "name": "Comment les complications affectent-elles la qualité de vie ?", "position": 23, "acceptedAnswer": { "@type": "Answer", "text": "Elles peuvent réduire la qualité de vie en provoquant douleur, fatigue et limitations fonctionnelles." } }, { "@type": "Question", "name": "Les complications peuvent-elles être réversibles ?", "position": 24, "acceptedAnswer": { "@type": "Answer", "text": "Certaines complications peuvent être réversibles avec un traitement approprié et précoce." } }, { "@type": "Question", "name": "Y a-t-il un risque accru de cancer avec des anomalies de thrombospondine-1 ?", "position": 25, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des niveaux élevés de thrombospondine-1 sont associés à un risque accru de certains cancers." } }, { "@type": "Question", "name": "Quels sont les facteurs de risque pour les troubles de thrombospondine-1 ?", "position": 26, "acceptedAnswer": { "@type": "Answer", "text": "Les facteurs incluent des antécédents familiaux, des maladies auto-immunes et le tabagisme." } }, { "@type": "Question", "name": "L'âge influence-t-il les niveaux de thrombospondine-1 ?", "position": 27, "acceptedAnswer": { "@type": "Answer", "text": "Oui, les niveaux peuvent varier avec l'âge, souvent augmentant chez les personnes âgées." } }, { "@type": "Question", "name": "Le mode de vie peut-il affecter la thrombospondine-1 ?", "position": 28, "acceptedAnswer": { "@type": "Answer", "text": "Oui, un mode de vie sédentaire et une mauvaise alimentation peuvent aggraver les niveaux." } }, { "@type": "Question", "name": "Les infections peuvent-elles influencer la thrombospondine-1 ?", "position": 29, "acceptedAnswer": { "@type": "Answer", "text": "Certaines infections peuvent augmenter les niveaux de thrombospondine-1 en réponse à l'inflammation." } }, { "@type": "Question", "name": "Le stress psychologique est-il un facteur de risque ?", "position": 30, "acceptedAnswer": { "@type": "Answer", "text": "Oui, le stress chronique peut affecter la régulation de la thrombospondine-1 et aggraver les symptômes." } } ] } ] }

Sources (10000 au total)

Service Demand for and Awareness of a Primary Healthcare Pilot Project for People With Disabilities.

This study investigated the demand for and awareness of a primary healthcare pilot project for people with disabilities; it also sought to identify relevant determinants for demand and awareness using... This study is a secondary analysis of data from the population-based survey conducted in Gyeonggi Regional Health & Medical Center for People with Disabilities. The data was designed with quota ra... Awareness of the service (12.1%) was remarkably low, while the demand (80.5%) was high. The gap between respondents who needed the service but were unaware of it differed according to age, education, ... Chronic disease and an unmet need for medical care were key determinants of service demand, while the severity of disability was not. Thus, there is a need to review the initiative that defines servic...

[The KomMent study: a pilot project on structured interprofessional communication in uro-oncology].

Communication and interprofessional collaboration with patients diagnosed with cancer is challenging. Structured communication training has not yet been integrated into postgraduate medical education.... A needs assessment was conducted using focus groups and individual interviews. Learning objectives were aligned with (inter)national learning objective catalogs. The ICT was developed using the six-st... Physician participation rates in the workshops were 83.0% and nursing participation rates were 58.3%. Utilization of the workplace-based training was 97%. The physicians evaluated the ICT very positiv... The implementation of an ICT with 80 teaching units is successfully feasible in a urological clinic and leads to a sustainable improvement of the communication culture, among other things through ment...

[Psychiatric-Psychotherapeutic Care in Crisis: Results of the LeiP#Netz Pilot Project].

Analysis of psychiatric-psychotherapeutic crisis services in the Leipzig Psychiatry Network (LeiP#netz), assigning the services to the functional areas of the FBM according to Steinhart and Wienberg.... A standardized survey of crisis care was conducted using the functions "complex outpatient treatment", "access to acute psychotherapy in crisis", and "24 h complex, intensive treatment" by means of fa... A total of 31 measures were recorded for the three functions. All crisis care services were highly utilized; in up to one-third of cases, no services could be provided when demand was requested. Servi... Crisis care services for severely mentally ill people are available in various constellations in the study region. Low-threshold 24/7 crisis services need to be expanded....

Adaptation of Screening Tools for Social Determinants of Health in Pregnancy: A Pilot Project.

Social determinants of health (SDOH) and stress during pregnancy may contribute to adverse pregnancy outcomes. The objective of this in the field pilot project was to develop a comprehensive screening... Pregnant patients accessing prenatal care at a single site of an urban Federally Qualified Health Center were recruited during prenatal visits to complete a Social Determinants of Health in Pregnancy ... Between April 2018 and March 2019, 135 pregnant participants completed SIPT. Ninety-one percent of patients scored positive on at least one screener, 54% to three or more screeners.... Despite guidelines to screen for SDOH during pregnancy there is no universal tool. Our pilot project demonstrated the concurrent use of adapted screening tools where participants reported at least one...

Colorectal Cancer Screening Pilot Project in Tehran-Iran, a Feasibility Study.

Colorectal cancer (CRC) is the third most common cancer in Iran, where there is no organised CRC-screening programme. This study aimed to evaluate feasibility of CRC screening using a qualitative feca... In this feasibility study, 7039 individuals aged 50-75 years were invited by community health workers (CHWs) in southern Tehran and its suburban districts between April 2018 and November 2019. The CHW... Acceptance rate at initial invitation was 71.7%. From 4974 average-risk adults (1600 males and 3374 females) who were offered FIT, 96.8% (n=4813) provided valid samples, of whom 471 (9.8%) tested posi... Our results partially support the feasibility of scaling up organized CRC-screening through the existing healthcare system in Iran; it remains to be discussed carefully to ensure the capacity of healt...

Conducting two evidence syntheses in six weeks - experiences with and evaluation of a pilot project.

Evidence synthesis organisations are trying to meet commissioners' needs for rapid responses to their evidence synthesis commissions. In this project we piloted an intensive process, working to comple... In a pre-planning phase, an intensive work group was established, and two commissions were selected for this pilot project. The evidence synthesis process was divided into two phases: planning and int... During the planning phase, teams identified significant uncertainties regarding scopes, research questions, and inclusion criteria. To address this, they engaged with commissioners earlier than origin... Overall, the intensive process fostered focus and productivity, allowing teams to manage short-term deliverables effectively. The researchers preferred working intensively with one evidence synthesis ...

[Implementation of a Pilot Project Supporting Parents Suffering from Cancer with Underage Children].

Families with one parent suffering from cancer are exposed to extraordinary emotional and organizational burdens, affecting underaged children. To help coordinated access to social and logistic suppor... A cross-sectional observational study was conducted using a mixed-method approach. Semi-structured written expert surveys (n=10) and secondary analysis of routine data of the care model (n=171 familie... Quantitative secondary analysis: The participating families had 1-7 children (median (m) 2, range (s) 6). In 66% of the cases, the mother was affected by cancer, in 20% the diseased parent was in a si... The data collected indicate that in families, matching the German average in their socio-demographic characteristics, a great need for organizational support develops as soon as one parent becomes sic...

A pilot project of expert nurses for the follow-up of complex intravenous antimicrobial treatment.

To report a pilot project of expert nurses for outpatient parenteral antimicrobial treatment (OPAT) follow-up.... Three nurses with specific training on antibiotics started a state-funded programme including: i) consultations for OPAT follow-up; ii) hotline for satellite hospitals; iii) peer training. Patients' d... From December 2020 to December 2021, 118 patients (median age 66.5 years [52-75], male-to-female ratio 2.5) were enrolled, for a total of 621 consultations. Patients were mostly on OPAT for bone and j... Nurses may be important actors for OPAT follow-up....

Implementation of entrustable professional activities into fellowship council accredited programs: a pilot project.

The Fellowship Council (FC) is transitioning to a competency-based medical education (CBME) model, including the introduction of Entrustable Professional Activities (EPAs) for training and assessment ... The FC coordinated the development of EPAs in collaboration with the sponsoring societies for Advanced GI/MIS, Bariatrics, Foregut, Endoscopy and Hepatopancreaticobiliary (HPB) fellowships encompassin... The 15 participating programs included 18 fellows and 106 faculty. A total of 655 assessments were initiated with 429 (65%) completed. The average (SD) number of EPAs completed for each fellow was 24(... A competency-based assessment framework was developed by the FC and piloted in several programs. Participation was variable and required ongoing strategies to address barriers. The pilot project has p...