Shared decision-making in Argentina in 2022.
Argentina is an upper-middle income country located in South America with an estimated population of 46.2 million inhabitants. There is no unified research agenda or government initiatives encouraging...
Motifs EF Hands : Questions médicales fréquentes
Questions fréquentes et termes MeSH associés
Diagnostic 5
#1
Comment diagnostiquer un motif EF Hand ?
Le diagnostic repose sur des analyses biochimiques et des études de structure protéique.
#2
Quels tests sont utilisés pour les motifs EF Hands ?
Des techniques comme la spectroscopie RMN et la cristallographie aux rayons X sont utilisées.
#3
Les motifs EF Hands sont-ils visibles par imagerie ?
Non, ils nécessitent des méthodes biochimiques pour être étudiés, pas d'imagerie classique.
#4
Peut-on identifier des mutations dans les motifs EF Hands ?
Oui, des techniques de séquençage génétique peuvent révéler des mutations affectant ces motifs.
#5
Quel rôle joue la bioinformatique dans le diagnostic ?
La bioinformatique aide à prédire la structure et la fonction des motifs EF Hands.
Symptômes 5
#1
Quels symptômes sont associés aux motifs EF Hands ?
Les motifs EF Hands ne présentent pas de symptômes directs, mais affectent des fonctions cellulaires.
#2
Les motifs EF Hands sont-ils liés à des maladies ?
Oui, des anomalies dans ces motifs peuvent être associées à des maladies comme l'ataxie.
#3
Comment les motifs EF Hands affectent-ils la signalisation cellulaire ?
Ils régulent la signalisation calcique, influençant divers processus cellulaires.
#4
Y a-t-il des signes cliniques de dysfonction des motifs EF Hands ?
Des signes indirects peuvent apparaître, comme des troubles neurologiques ou musculaires.
#5
Les motifs EF Hands influencent-ils le métabolisme ?
Oui, ils jouent un rôle dans le métabolisme cellulaire en régulant le calcium.
Prévention 5
#1
Peut-on prévenir les anomalies des motifs EF Hands ?
La prévention est difficile, mais un mode de vie sain peut réduire les risques associés.
#2
Y a-t-il des facteurs environnementaux à considérer ?
Oui, l'exposition à des toxines peut affecter la fonction des motifs EF Hands.
#3
Comment le stress influence-t-il les motifs EF Hands ?
Le stress peut perturber la signalisation calcique, affectant indirectement ces motifs.
#4
L'exercice physique a-t-il un impact sur ces motifs ?
L'exercice régule la signalisation calcique, ce qui peut soutenir la fonction des motifs.
#5
Les suppléments de calcium sont-ils bénéfiques ?
Des suppléments peuvent aider à maintenir un bon équilibre calcique, soutenant la fonction.
Traitements 5
#1
Quels traitements ciblent les motifs EF Hands ?
Actuellement, il n'existe pas de traitements spécifiques pour les motifs EF Hands.
#2
Peut-on modifier les motifs EF Hands par thérapie génique ?
La thérapie génique pourrait potentiellement corriger des mutations affectant ces motifs.
#3
Les médicaments peuvent-ils influencer les motifs EF Hands ?
Certains médicaments modulent la signalisation calcique, indirectement affectant ces motifs.
#4
Y a-t-il des approches expérimentales pour traiter les anomalies ?
Des recherches sont en cours sur des peptides et des inhibiteurs ciblant les motifs EF Hands.
#5
Comment la nutrition peut-elle influencer les motifs EF Hands ?
Une nutrition adéquate en calcium et en magnésium peut soutenir leur fonction.
Complications 5
#1
Quelles complications peuvent survenir avec des motifs EF Hands défectueux ?
Des complications peuvent inclure des troubles neurologiques et musculaires.
#2
Les motifs EF Hands sont-ils liés à des cancers ?
Des études suggèrent un lien potentiel entre des anomalies et certains types de cancer.
#3
Comment les complications affectent-elles la qualité de vie ?
Elles peuvent entraîner des limitations fonctionnelles et des douleurs chroniques.
#4
Y a-t-il des risques de maladies cardiovasculaires ?
Des dysfonctionnements calciques peuvent contribuer à des maladies cardiovasculaires.
#5
Les complications sont-elles réversibles ?
Certaines complications peuvent être gérées, mais d'autres peuvent être permanentes.
Facteurs de risque 5
#1
Quels sont les facteurs de risque pour les anomalies des motifs EF Hands ?
Les facteurs incluent des prédispositions génétiques et des expositions environnementales.
#2
L'âge influence-t-il les motifs EF Hands ?
Oui, le vieillissement peut affecter la fonction des motifs EF Hands et la signalisation calcique.
#3
Le mode de vie joue-t-il un rôle dans les risques ?
Un mode de vie sédentaire et une mauvaise alimentation augmentent les risques.
#4
Les antécédents familiaux sont-ils un facteur de risque ?
Oui, des antécédents familiaux de maladies génétiques peuvent augmenter le risque.
#5
Les infections peuvent-elles affecter les motifs EF Hands ?
Certaines infections peuvent perturber la signalisation calcique, affectant ces motifs.
Contenu validé par Dr Olivier Menir
Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 14/03/2025
Contenu vérifié selon les dernières recommandations médicales
Auteurs principaux
Peter B Stathopulos
4 publications dans cette catégorie
Affiliations :
- Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario, Canada.
Publications dans "Motifs EF Hands" :
-
The leucine zipper EF-hand containing transmembrane protein-1 EF-hand is a tripartite calcium, temperature, and pH sensor.
Protein science : a publication of the Protein Society 2021-03-02
-
Molecular Mechanisms of Leucine Zipper EF-Hand Containing Transmembrane Protein-1 Function in Health and Disease.
International journal of molecular sciences 2019-01-12
-
Coordination of a Single Calcium Ion in the EF-hand Maintains the Off State of the Stromal Interaction Molecule Luminal Domain.
Journal of molecular biology 2019-10-15
-
An AI-informed NMR structure reveals an extraordinary LETM1 F-EF-hand domain that functions as a two-way regulator of mitochondrial calcium.
Structure (London, England : 1993) 2024-09-17
Qi-Tong Lin
3 publications dans cette catégorie
Affiliations :
- Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario, Canada.
Publications dans "Motifs EF Hands" :
-
The leucine zipper EF-hand containing transmembrane protein-1 EF-hand is a tripartite calcium, temperature, and pH sensor.
Protein science : a publication of the Protein Society 2021-03-02
-
Molecular Mechanisms of Leucine Zipper EF-Hand Containing Transmembrane Protein-1 Function in Health and Disease.
International journal of molecular sciences 2019-01-12
-
An AI-informed NMR structure reveals an extraordinary LETM1 F-EF-hand domain that functions as a two-way regulator of mitochondrial calcium.
Structure (London, England : 1993) 2024-09-17
Biraj B Kayastha
3 publications dans cette catégorie
Affiliations :
- Department of Microbiology and Molecular Genetics, Oklahoma State University, Stillwater, OK, 74078, USA.
Publications dans "Motifs EF Hands" :
-
EF-hand protein, EfhP, specifically binds Ca
Scientific reports 2022-05-25
-
EF-hand calcium sensor, EfhP, controls transcriptional regulation of iron uptake by calcium in
mBio 2024-10-22
-
EF-Hand Calcium Sensor, EfhP, Controls Transcriptional Regulation of Iron Uptake by Calcium in
bioRxiv : the preprint server for biology 2024-01-10
Aya Kubo
3 publications dans cette catégorie
Affiliations :
- Department of Microbiology and Molecular Genetics, Oklahoma State University, Stillwater, OK, 74078, USA.
Publications dans "Motifs EF Hands" :
-
EF-hand protein, EfhP, specifically binds Ca
Scientific reports 2022-05-25
-
EF-hand calcium sensor, EfhP, controls transcriptional regulation of iron uptake by calcium in
mBio 2024-10-22
-
EF-Hand Calcium Sensor, EfhP, Controls Transcriptional Regulation of Iron Uptake by Calcium in
bioRxiv : the preprint server for biology 2024-01-10
Jacob Burch-Konda
3 publications dans cette catégorie
Affiliations :
- Department of Microbiology and Molecular Genetics, Oklahoma State University, Stillwater, OK, 74078, USA.
Publications dans "Motifs EF Hands" :
-
EF-hand protein, EfhP, specifically binds Ca
Scientific reports 2022-05-25
-
EF-hand calcium sensor, EfhP, controls transcriptional regulation of iron uptake by calcium in
mBio 2024-10-22
-
EF-Hand Calcium Sensor, EfhP, Controls Transcriptional Regulation of Iron Uptake by Calcium in
bioRxiv : the preprint server for biology 2024-01-10
Rendi R Rogers
3 publications dans cette catégorie
Affiliations :
- Department of Microbiology and Molecular Genetics, Oklahoma State University, Stillwater, OK, 74078, USA.
Publications dans "Motifs EF Hands" :
-
EF-hand protein, EfhP, specifically binds Ca
Scientific reports 2022-05-25
-
EF-hand calcium sensor, EfhP, controls transcriptional regulation of iron uptake by calcium in
mBio 2024-10-22
-
EF-Hand Calcium Sensor, EfhP, Controls Transcriptional Regulation of Iron Uptake by Calcium in
bioRxiv : the preprint server for biology 2024-01-10
Marianna A Patrauchan
3 publications dans cette catégorie
Affiliations :
- Department of Microbiology and Molecular Genetics, Oklahoma State University, Stillwater, OK, 74078, USA. m.patrauchan@okstate.edu.
Publications dans "Motifs EF Hands" :
-
EF-hand protein, EfhP, specifically binds Ca
Scientific reports 2022-05-25
-
EF-hand calcium sensor, EfhP, controls transcriptional regulation of iron uptake by calcium in
mBio 2024-10-22
-
EF-Hand Calcium Sensor, EfhP, Controls Transcriptional Regulation of Iron Uptake by Calcium in
bioRxiv : the preprint server for biology 2024-01-10
Michael R Kreutz
2 publications dans cette catégorie
Affiliations :
- RG Neuroplasticity, Leibniz Institute for Neurobiology, Magdeburg, Germany.
- Leibniz Group 'Dendritic Organelles and Synaptic Function', University Medical Center Hamburg-Eppendorf, Center for Molecular Neurobiology, ZMNH, Hamburg, Germany.
Publications dans "Motifs EF Hands" :
-
Tryptophan Scanning Mutagenesis of EF-Hand Motifs.
Methods in molecular biology (Clifton, N.J.)
-
Caldendrin and Calneurons-EF-Hand CaM-Like Calcium Sensors With Unique Features and Specialized Neuronal Functions.
Frontiers in molecular neuroscience 2019-02-06
Yogendra Sharma
2 publications dans cette catégorie
Affiliations :
- CSIR-Centre for Cellular and Molecular Biology (CCMB), Hyderabad, India. yogendra@ccmb.res.in.
- Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India. yogendra@ccmb.res.in.
Publications dans "Motifs EF Hands" :
-
Tryptophan Scanning Mutagenesis of EF-Hand Motifs.
Methods in molecular biology (Clifton, N.J.)
-
Conformational scanning of individual EF-hand motifs of calcium sensor protein centrin-1.
Biochemical and biophysical research communications 2021-07-14
Eugene A Permyakov
2 publications dans cette catégorie
Affiliations :
- Institute for Biological Instrumentation of the Russian Academy of Sciences, Federal Research Center Pushchino Scientific Center for Biological Research of the Russian Academy of Sciences, 142290 Pushchino, Russia. epermyak@yandex.ru.
- Department of Biomedical Engineering, Pushchino State Institute of Natural Sciences, 142290 Pushchino, Russia. epermyak@yandex.ru.
Publications dans "Motifs EF Hands" :
-
Experimental Insight into the Structural and Functional Roles of the 'Black' and 'Gray' Clusters in Recoverin, a Calcium Binding Protein with Four EF-Hand Motifs.
Molecules (Basel, Switzerland) 2019-07-08
-
Strontium Binding to α-Parvalbumin, a Canonical Calcium-Binding Protein of the "EF-Hand" Family.
Biomolecules 2021-08-05
Myriam Achour
2 publications dans cette catégorie
Affiliations :
- Department of Microbiology and Molecular Genetics, Oklahoma State University, Stillwater, Oklahoma, USA.
Publications dans "Motifs EF Hands" :
-
EF-hand calcium sensor, EfhP, controls transcriptional regulation of iron uptake by calcium in
mBio 2024-10-22
-
EF-Hand Calcium Sensor, EfhP, Controls Transcriptional Regulation of Iron Uptake by Calcium in
bioRxiv : the preprint server for biology 2024-01-10
Mackenzie Hull
2 publications dans cette catégorie
Affiliations :
- Department of Microbiology and Molecular Genetics, Oklahoma State University, Stillwater, Oklahoma, USA.
Publications dans "Motifs EF Hands" :
-
EF-hand calcium sensor, EfhP, controls transcriptional regulation of iron uptake by calcium in
mBio 2024-10-22
-
EF-Hand Calcium Sensor, EfhP, Controls Transcriptional Regulation of Iron Uptake by Calcium in
bioRxiv : the preprint server for biology 2024-01-10
Reygan Braga
2 publications dans cette catégorie
Affiliations :
- Department of Microbiology and Molecular Genetics, Oklahoma State University, Stillwater, Oklahoma, USA.
Publications dans "Motifs EF Hands" :
-
EF-hand calcium sensor, EfhP, controls transcriptional regulation of iron uptake by calcium in
mBio 2024-10-22
-
EF-Hand Calcium Sensor, EfhP, Controls Transcriptional Regulation of Iron Uptake by Calcium in
bioRxiv : the preprint server for biology 2024-01-10
Lorelei Winton
2 publications dans cette catégorie
Affiliations :
- Department of Microbiology and Molecular Genetics, Oklahoma State University, Stillwater, Oklahoma, USA.
Publications dans "Motifs EF Hands" :
-
EF-hand calcium sensor, EfhP, controls transcriptional regulation of iron uptake by calcium in
mBio 2024-10-22
-
EF-Hand Calcium Sensor, EfhP, Controls Transcriptional Regulation of Iron Uptake by Calcium in
bioRxiv : the preprint server for biology 2024-01-10
Erika I Lutter
2 publications dans cette catégorie
Affiliations :
- Department of Microbiology and Molecular Genetics, Oklahoma State University, Stillwater, Oklahoma, USA.
Publications dans "Motifs EF Hands" :
-
EF-hand calcium sensor, EfhP, controls transcriptional regulation of iron uptake by calcium in
mBio 2024-10-22
-
EF-Hand Calcium Sensor, EfhP, Controls Transcriptional Regulation of Iron Uptake by Calcium in
bioRxiv : the preprint server for biology 2024-01-10
Samiol Azam
2 publications dans cette catégorie
Affiliations :
- Department of Chemistry and Biochemistry, Florida International University, Miami, FL 33199, USA.
Publications dans "Motifs EF Hands" :
-
Nanomolar affinity of EF-hands in neuronal calcium sensor 1 for bivalent cations Pb2+, Mn2+, and Hg2.
Metallomics : integrated biometal science
-
EF-hands in Neuronal Calcium Sensor Downstream Regulatory Element Antagonist Modulator Demonstrate Submillimolar Affinity for Li
ACS chemical neuroscience 2020-08-24
Jaroslava Miksovska
2 publications dans cette catégorie
Affiliations :
- Department of Chemistry and Biochemistry, Florida International University, Miami, FL 33199, USA.
- Biomolecular Sciences Institute, Florida International University, Miami 33199, USA.
Publications dans "Motifs EF Hands" :
-
Nanomolar affinity of EF-hands in neuronal calcium sensor 1 for bivalent cations Pb2+, Mn2+, and Hg2.
Metallomics : integrated biometal science
-
EF-hands in Neuronal Calcium Sensor Downstream Regulatory Element Antagonist Modulator Demonstrate Submillimolar Affinity for Li
ACS chemical neuroscience 2020-08-24
Masatoshi Maki
2 publications dans cette catégorie
Affiliations :
- Department of Applied Biosciences, Graduate School of Bioagricultural Sciences, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8601, Japan.
Publications dans "Motifs EF Hands" :
-
The Penta-EF-Hand ALG-2 Protein Interacts with the Cytosolic Domain of the SOCE Regulator SARAF and Interferes with Ubiquitination.
International journal of molecular sciences 2020-08-31
-
Structures and functions of penta-EF-hand calcium-binding proteins and their interacting partners: enigmatic relationships between ALG-2 and calpain-7.
Bioscience, biotechnology, and biochemistry 2019-12-09
Uday Kiran
1 publication dans cette catégorie
Affiliations :
- CSIR-Centre for Cellular and Molecular Biology (CCMB), Hyderabad, India.
- Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.
Publications dans "Motifs EF Hands" :
-
Tryptophan Scanning Mutagenesis of EF-Hand Motifs.
Methods in molecular biology (Clifton, N.J.)
Asima Chakraborty
1 publication dans cette catégorie
Affiliations :
- CSIR-Centre for Cellular and Molecular Biology (CCMB), Hyderabad, India. asimachakraborty@gmail.com.
Publications dans "Motifs EF Hands" :
-
Tryptophan Scanning Mutagenesis of EF-Hand Motifs.
Methods in molecular biology (Clifton, N.J.)
Sources (10000 au total)
Implementing shared decision-making in Australia.
Person-centred care (PCC) and shared decision-making (SDM) are part of national clinical standards for an increasing number of areas of health care delivery. In addition to existing standards for accr...
Epistemic justice is the basis of shared decision making.
There is little evidence that share decision-making (SDM) is being successfully implemented, with a significant gap between theory and clinical practice. In this article we look at SDM explicitly ackn... We propose to see conditions for shared decision-making in terms of epistemic justice, an explicit acknowledgment and acceptance of the legitimacy of healthcare users and their accounts and knowledges... The epistemic-justice perspective we adopt leads to at least three implications for clinical practices. First, clinical training must go beyond the development of communication skills and focus more o...
Shared decision making in the treatment of pediatric strabismus.
To quantify the results of shared decision making in pediatric strabismus surgery from the parent perspective using the nine-item Shared Decision Making (SDM) Questionnaire and the associations of SDM... Consecutive parents of children 2-14 years of age with concomitant manifest strabismus that consented to strabismus surgery were surveyed using the SDM Questionnaire. A four-point Likert scale was use... A total of 100 parents (86 women) completed the survey and were included. Significant differences for SDM score were found between individuals with university-level versus the other three educational ... In our study cohort, SDM score was correlated with educational level. Satisfaction was greater among responders with higher SDM scores, indicating that SDM may help improve parent-reported satisfactio...
Moving shared decision-making forward in Iran.
Although there have been breakthroughs in patients' rights and informed consent legislation in Iran during the last few years, there is still no policy regarding shared decision-making (SDM). Besides,...
Shared decision making in rheumatology: A scoping review.
Shared decision making is a collaborative process where patients and clinicians work together to understand the patient's situation and to determine how best to address it. While shared decision makin... To perform a scoping review of research on shared decision making in rheumatology METHODS: We analyzed literature on shared decision making in rheumatology from Ovid MEDLINE, PsycINFO, Sciverse Scopus... Of 3191 articles screened, 63 studies were included for analysis. Shared decision making in rheumatology improves patient satisfaction and adherence to treatment plans. We identified 13 patient decisi... Our review identified 63 studies of shared decision making in rheumatology, including 13 studies of patient decision aids. Future areas of research include identifying tools for shared decision making...
For which decisions is Shared Decision Making considered appropriate? - A systematic review.
To identify decision characteristics for which SDM authors deem SDM appropriate or not, and what arguments are used.... We applied two search strategies: we included SDM models from an earlier review (strategy 1) and conducted a new search in eight databases to include papers other than describing an SDM model, such as... From the 92 included papers, we identified 18 decision characteristics for which authors deemed SDM appropriate, including preference-sensitive, equipoise and decisions where patient commitment is nee... The findings of this review show the broad range of decision characteristics for which authors deem SDM appropriate, the ambiguity of some, and potential limits of SDM.... The findings can stimulate clinicians to (re)consider pursuing SDM in situations in which they did not before. Additionally, it can inform SDM campaigns and educational programs as it shows for which ...
Shared decision making with black patients: A scoping review.
The purpose of this review is to explore the breadth of research conducted on SDM in the care of Black patients.... We conducted a scoping review following the methodological framework outlined by the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) checklist. We searched articles related... After removal of duplicates and screening, 30 articles were included in the final analysis. Black patients and clinician were found to not share the same understanding of SDM, and patients highly valu... SDM has the potential to improve health outcomes in Black patients when implemented contextually within Black patients' experiences and concerns. Significant barriers such as clinician mistrust exist,...
Shared decision making and advance care planning: a systematic literature review and novel decision-making model.
Shared decision making (SDM) and advance care planning (ACP) are important evidence and ethics based concepts that can be translated in communication tools to aid the treatment decision-making process... In order to assess how SDM and ACP is applied in usual care, we have performed a systematic literature review. The included studies have been analysed by means of thematic analysis as well as abductiv... The search in Medline, Cinahl, Embase, Scopus, Web of science, Psychinfo and Cochrane revealed 15 studies. Eleven describe various steps of SDM while four studies discuss the documentation of goals of... To be able to make informed choices about immediate and future care, patients should be engaged in both SDM and ACP decision-making processes. This allows for an iterative process in which each import...
Shared Decision Making in Psychiatry: Dissolving the Responsibility Problem.
Person centered care (PCC) invites ideas of shared responsibility as a direct result of its shared decision making (SDM) process. The intersection of PCC and psychiatric contexts brings about what I r...