questionsmedicales.fr
Phénomènes chimiques
Phénomènes biochimiques
Stabilité de l'ARN
Stabilité de l'ARN : Questions médicales fréquentes
Termes MeSH sélectionnés :
Interprofessional Relations
Diagnostic
5
Dégradation de l'ARN
Expression génique
Électrophorèse
Séquençage
Anomalies génétiques
Séquençage
ARN messager
Maladies génétiques
Symptômes
5
Fatigue
Maladies génétiques
Cancers
Troubles neurodégénératifs
Anomalies de croissance
Troubles métaboliques
Troubles neurologiques
Troubles immunitaires
Dysfonctionnement cellulaire
Expression génique
Prévention
5
Alimentation équilibrée
Mode de vie sain
Exercice physique
Santé cellulaire
Stress
Expression génique
Traitements
5
Thérapie génique
Médicaments stabilisateurs
Inhibiteurs
Dégradation de l'ARN
Antisens oligonucleotides
Médicaments
Thérapie génique
Expression génique
Essais cliniques
Traitements expérimentaux
Complications
5
Maladies génétiques
Cancers
Cancers
Mécanismes tumoraux
Maladies neurodégénératives
Risques neurologiques
Système immunitaire
Infections
Facteurs de risque
5
Mutations
Gènes régulateurs
Vieillissement
Expression génique
Infections virales
Stabilité de l'ARN
Tabagisme
Modifications de l'ARN
Carence nutritionnelle
Nutriments essentiels
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"name": "Comment évaluer la stabilité de l'ARN ?",
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"text": "On utilise des techniques comme le Northern blot et la PCR en temps réel."
}
},
{
"@type": "Question",
"name": "Quels marqueurs indiquent une instabilité de l'ARN ?",
"position": 2,
"acceptedAnswer": {
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"text": "Des niveaux élevés de dégradation et des variations dans l'expression génique peuvent indiquer une instabilité."
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{
"@type": "Question",
"name": "Quels tests sont utilisés pour mesurer l'ARN ?",
"position": 3,
"acceptedAnswer": {
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{
"@type": "Question",
"name": "Peut-on détecter des anomalies d'ARN ?",
"position": 4,
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"text": "Oui, des techniques comme le séquençage de nouvelle génération peuvent détecter des anomalies."
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{
"@type": "Question",
"name": "Quel rôle joue l'ARNm dans le diagnostic ?",
"position": 5,
"acceptedAnswer": {
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"text": "L'ARNm est crucial pour évaluer l'expression des gènes associés à des maladies."
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"@type": "Question",
"name": "Quels symptômes sont liés à l'instabilité de l'ARN ?",
"position": 6,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des symptômes variés peuvent apparaître, selon la maladie sous-jacente, comme la fatigue."
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{
"@type": "Question",
"name": "L'instabilité de l'ARN peut-elle causer des maladies ?",
"position": 7,
"acceptedAnswer": {
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"text": "Oui, elle est liée à des maladies comme certains cancers et des troubles neurodégénératifs."
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"@type": "Question",
"name": "Quels signes cliniques sont observés ?",
"position": 8,
"acceptedAnswer": {
"@type": "Answer",
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"@type": "Question",
"name": "Y a-t-il des symptômes spécifiques aux maladies liées à l'ARN ?",
"position": 9,
"acceptedAnswer": {
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"text": "Oui, des symptômes spécifiques peuvent inclure des troubles neurologiques ou immunitaires."
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"@type": "Question",
"name": "Comment l'instabilité de l'ARN affecte-t-elle la santé ?",
"position": 10,
"acceptedAnswer": {
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"text": "Elle peut perturber l'expression génique, entraînant des dysfonctionnements cellulaires."
}
},
{
"@type": "Question",
"name": "Comment prévenir l'instabilité de l'ARN ?",
"position": 11,
"acceptedAnswer": {
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"text": "Une alimentation équilibrée et un mode de vie sain peuvent aider à maintenir la stabilité de l'ARN."
}
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{
"@type": "Question",
"name": "Y a-t-il des facteurs environnementaux à éviter ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'exposition à des toxines et à des radiations peut affecter la stabilité de l'ARN."
}
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{
"@type": "Question",
"name": "L'exercice physique influence-t-il l'ARN ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'exercice régulier peut améliorer la santé cellulaire et la stabilité de l'ARN."
}
},
{
"@type": "Question",
"name": "Des suppléments peuvent-ils aider ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certains suppléments, comme les antioxydants, peuvent soutenir la stabilité de l'ARN."
}
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{
"@type": "Question",
"name": "Comment le stress affecte-t-il l'ARN ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le stress chronique peut altérer la stabilité de l'ARN et affecter l'expression génique."
}
},
{
"@type": "Question",
"name": "Quels traitements ciblent l'instabilité de l'ARN ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des thérapies géniques et des médicaments stabilisateurs d'ARN sont en développement."
}
},
{
"@type": "Question",
"name": "Peut-on utiliser des inhibiteurs pour stabiliser l'ARN ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certains inhibiteurs peuvent réduire la dégradation de l'ARN dans les cellules."
}
},
{
"@type": "Question",
"name": "Quels médicaments sont efficaces contre l'instabilité de l'ARN ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des médicaments comme les antisens oligonucleotides sont utilisés pour cibler l'ARN."
}
},
{
"@type": "Question",
"name": "Comment la thérapie génique aide-t-elle ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elle peut corriger les défauts d'ARN, améliorant ainsi l'expression génique."
}
},
{
"@type": "Question",
"name": "Y a-t-il des traitements expérimentaux ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des essais cliniques testent de nouvelles approches pour stabiliser l'ARN."
}
},
{
"@type": "Question",
"name": "Quelles complications peuvent survenir ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des complications incluent des maladies génétiques, des cancers et des troubles métaboliques."
}
},
{
"@type": "Question",
"name": "L'instabilité de l'ARN peut-elle entraîner des cancers ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'instabilité de l'ARN est souvent associée à des mécanismes tumoraux."
}
},
{
"@type": "Question",
"name": "Quels troubles métaboliques sont liés à l'ARN ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des troubles comme le diabète et l'obésité peuvent être influencés par l'instabilité de l'ARN."
}
},
{
"@type": "Question",
"name": "Y a-t-il des risques neurologiques ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des maladies neurodégénératives peuvent être exacerbées par l'instabilité de l'ARN."
}
},
{
"@type": "Question",
"name": "Comment l'instabilité de l'ARN affecte-t-elle le système immunitaire ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elle peut altérer la réponse immunitaire, rendant l'organisme plus vulnérable aux infections."
}
},
{
"@type": "Question",
"name": "Quels facteurs génétiques influencent l'ARN ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des mutations dans des gènes régulateurs peuvent affecter la stabilité de l'ARN."
}
},
{
"@type": "Question",
"name": "L'âge est-il un facteur de risque ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le vieillissement peut affecter la stabilité de l'ARN et l'expression génique."
}
},
{
"@type": "Question",
"name": "Les infections virales impactent-elles l'ARN ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines infections virales peuvent perturber la stabilité de l'ARN dans les cellules hôtes."
}
},
{
"@type": "Question",
"name": "Le tabagisme influence-t-il l'ARN ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le tabagisme peut induire des modifications qui affectent la stabilité de l'ARN."
}
},
{
"@type": "Question",
"name": "Y a-t-il des facteurs nutritionnels à considérer ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, une carence en nutriments essentiels peut compromettre la stabilité de l'ARN."
}
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}
Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 26/04/2025
Contenu vérifié selon les dernières recommandations médicales
3 publications dans cette catégorie
Affiliations :
Department of Chemistry, Stanford University, Stanford, CA 94305, USA.
Eterna Massive Open Laboratory.
Publications dans "Stabilité de l'ARN" :
3 publications dans cette catégorie
Affiliations :
Eterna Massive Open Laboratory.
Department of Chemical and Biological Engineering, Northwestern University, Evanston, IL 60208, USA.
Department of Biochemistry, Stanford University, Stanford, CA 94305, USA.
Publications dans "Stabilité de l'ARN" :
3 publications dans cette catégorie
Affiliations :
Eterna Massive Open Laboratory.
Publications dans "Stabilité de l'ARN" :
3 publications dans cette catégorie
Affiliations :
Eterna Massive Open Laboratory.
Publications dans "Stabilité de l'ARN" :
3 publications dans cette catégorie
Affiliations :
Eterna Massive Open Laboratory.
Department of Biochemistry, Stanford University, Stanford, CA 94305, USA.
Publications dans "Stabilité de l'ARN" :
3 publications dans cette catégorie
Affiliations :
Eterna Massive Open Laboratory.
Publications dans "Stabilité de l'ARN" :
3 publications dans cette catégorie
Affiliations :
Eterna Massive Open Laboratory.
Department of Biochemistry, Stanford University, Stanford, CA 94305, USA.
Department of Physics, Stanford University, Stanford, CA 94305, USA.
Publications dans "Stabilité de l'ARN" :
2 publications dans cette catégorie
Affiliations :
IMBA-Institute of Molecular Biotechnology, Vienna Biocenter (VBC), Vienna, Austria.
Publications dans "Stabilité de l'ARN" :
2 publications dans cette catégorie
Affiliations :
IMBA-Institute of Molecular Biotechnology, Vienna Biocenter (VBC), Vienna, Austria.
Publications dans "Stabilité de l'ARN" :
2 publications dans cette catégorie
Affiliations :
IMBA-Institute of Molecular Biotechnology, Vienna Biocenter (VBC), Vienna, Austria. stefan.ameres@univie.ac.at.
Max Perutz Labs, University of Vienna, Vienna Biocenter (VBC), Vienna, Austria. stefan.ameres@univie.ac.at.
Publications dans "Stabilité de l'ARN" :
2 publications dans cette catégorie
Affiliations :
Department of Chemistry and Biochemistry, The Ohio State University, Columbus, OH 43210, USA.
Center for RNA Biology, The Ohio State University, Columbus, OH 43210, USA.
Institute of Biophysics, Ilia State University, Tbilisi, 0162, Republic of Georgia.
Publications dans "Stabilité de l'ARN" :
2 publications dans cette catégorie
Affiliations :
Department of Chemistry, University of California, Berkeley, Berkeley, California 94720, USA.
Publications dans "Stabilité de l'ARN" :
2 publications dans cette catégorie
Affiliations :
Department of Chemistry, University of California, Berkeley, Berkeley, California 94720, USA j-h-doudna-cate@berkeley.edu.
Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, California 94720, USA.
Molecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, California 94720, USA.
Publications dans "Stabilité de l'ARN" :
2 publications dans cette catégorie
Affiliations :
Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06536.
HHMI, Yale University School of Medicine, New Haven, CT 06536.
Publications dans "Stabilité de l'ARN" :
2 publications dans cette catégorie
Affiliations :
Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06536.
Publications dans "Stabilité de l'ARN" :
2 publications dans cette catégorie
Affiliations :
Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06536.
HHMI, Yale University School of Medicine, New Haven, CT 06536.
Publications dans "Stabilité de l'ARN" :
2 publications dans cette catégorie
Affiliations :
Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06536.
HHMI, Yale University School of Medicine, New Haven, CT 06536.
Tata Institute of Fundamental Research Centre for Interdisciplinary Sciences, Tata Institute of Fundamental Research, 10 500046 Hyderabad, India.
Publications dans "Stabilité de l'ARN" :
2 publications dans cette catégorie
Affiliations :
Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06536; wahc@stanford.edu LP26@cornell.edu joan.steitz@yale.edu.
HHMI, Yale University School of Medicine, New Haven, CT 06536.
Publications dans "Stabilité de l'ARN" :
2 publications dans cette catégorie
Affiliations :
Cavendish Laboratory, Maxwell Centre, Department of Physics, University of Cambridge, Cambridge, United Kingdom. Electronic address: jr752@cam.ac.uk.
Publications dans "Stabilité de l'ARN" :
2 publications dans cette catégorie
Affiliations :
Department of Genetics, Stanford University, Stanford, CA, 94305, USA.
Publications dans "Stabilité de l'ARN" :
Post-partum haemorrhage (PPH) is an obstetric emergency that requires effective teamwork under complex conditions. We explored healthcare team performance for women who suffered a PPH, focusing on rel...
In collaboration with clinical teams, we implemented structural, process and relational interventions to improve teamwork in PPH cases. We were guided by the conceptual framework of Relational Coordin...
Four overarching themes were identified: 1) Teamwork, clear roles and identified leadership are critical. 2) Relational factors powerfully underpin teamwork behaviours-shared goals, shared knowledge, ...
Teamwork, relationships, and the context of care can be actively shaped in partnership with clinicians to support high performance in maternity care. We present our multifaceted approach as a guide fo...
It is unknown whether interprofessional identity is able to explain interprofessional behaviours. Extended professional identity theory provides clues by combining two psychological identity approache...
Participants of this double-blinded study were 47 dentistry and 41 dental hygiene students (86.3% response) without interprofessional education (IPE) experience. Group productivity was used as indicat...
No interprofessional identity differences were found with regard to gender and profession. The mean difference between groups with low versus high interprofessional identity was 0.5 (M = 3.4; SD = 0.5...
Interprofessional identity has a positive effect on congruent interprofessional behaviours after 10 weeks. More research is required to understand interprofessional identity in relation to performance...
Visual impairment and blindness affect an estimated 2.2 billion people worldwide. Accessible low-cost diagnostic tools and interprofessional education and collaborative practice are part of ongoing st...
An innovative patient-centred interprofessional communication concept with advanced lung cancer patients (Heidelberg Milestone Communication Approach, MCA) has been developed and implemented. Role cha...
In a longitudinal study, 3 of the 4 subscales of the validated German translation of the University of the West of England Interprofessional Questionnaire (UWE-IP-D) were collected prior to implementa...
The survey with 87 staff (44 nurses, 13 physicians, 12 psycho-social staff, 7 therapists, and 11 others) participating at least once found heterogeneous attitudes. 'Communication and Teamwork' and 'In...
Positive experiences and potential shortfalls in the implementation were observed. Future introductions of interprofessional communication concepts require further activities which should address the ...
DRKS00013469 / Date of registration: 22/12/2017....
Interprofessional education (IPE) harnesses the power of teams to facilitate collaborative learning across disciplines. However, prior research has not paid sufficient attention to the role of team-le...
To test whether interprofessional attitudes at the team and student levels predict IPE collaboration outcomes, conducted multilevel modeling. We used the pretest and posttest data from 323 healthcare ...
Among the interprofessional attitudes, "teamwork, roles, and responsibilities" was found to be the best predictor of IPE outcomes, both at the student and team levels. Students who recognized the bene...
Students' attitudes towards teamwork, roles, and responsibilities in interprofessional collaborative practice, both at the student and team levels, are important to attaining positive student- and tea...
Interprofessional education programs in university settings have facilitated the development of student attributes needed to become a team-player, understand roles and responsibilities of other health...
To examine readiness of undergraduate nursing students for interprofessional learning and interprofessional socialisation....
A cross-sectional design was used to examine the correlation between interprofessional learning and socialisation, and group differences between mode of study, year level, and prior healthcare experie...
A large Australian regional university, across two campuses....
A total of 103 undergraduate nursing students across year levels, including 58 enrolled on-campus, and 45 studying externally....
Students completed an online survey using the Readiness for Interprofessional Learning Scale and the Interprofessional Socialisation and Valuing Scale. Data analyses included independent t-tests, and ...
No significant differences in student readiness for interprofessional learning or interprofessional socialisation were found between on-campus and external modes of study and between healthcare experi...
Readiness for interprofessional learning and interprofessional socialisation and were not impacted by the students' mode of study; however, previous experience in the healthcare industry and duration ...
Teamwork and communication are essential tools for doctors, nurses and other team members in the management of critically ill patients. Early interprofessional education during study, using acute care...
A comparative sequential quantitative-qualitative study was used to understand interprofessional learning outcomes in nursing and medical students after simulation of acute care. Students were assigne...
One hundred and ninety-one students participated in this study (131 medical, 60 nursing students). No differences were found between the intervention and control group in overall ICCAS scores for both...
Interprofessional simulation training did show measurable growth of interprofessional competencies, but so did uniprofessional training. Both medical and nursing students reported increased awareness ...
We describe the development and student evaluation of a collaborative health service provider and higher education institution initiative designed to deliver an Interprofessional Education (IPE) pilot...
For future success in the modern health care environment, health professions students require effective interprofessional education experiences to develop their perceptions of other professionals on t...
The ISPE involved collaboration among students to conduct a subjective interview. Students from six health care professions individually interviewed a simulated patient while being observed by student...
Over 4 consecutive academic years, 1,265 students completed the ISPE, and 1,028 completed the pre- and post-ISPE surveys. Analysis of the survey responses indicated that the ISPE enhanced student awar...
A single ISPE had a significant impact on prelicensure students' perceptions. The ISPE is a novel and effective approach to interprofessional education that students appreciate....
It has been difficult to demonstrate that interprofessional education (IPE) and interprofessional collaboration (IPC) have positive effects on patient care quality, cost effectiveness of patient care,...